James S O McCullagh (James McCullagh, James S O Mccullagh)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 35

Top Topics

Knee Osteoarthritis

Mass Spectrometry

Machine Learning

Histone Deacetylase

Top Venues

Science translational medicine

Nature cardiovascular research

Analytical chemistry

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Rebecca Clarke, Tehmina Bharucha, Benediktus Yohan Arman, Bevin Gangadharan, Laura Gomez Fernandez, Sara Mosca, Qianqi Lin, Kerlijn Van Assche, Robert Stokes, Susanna J Dunachie, Michael Deats, Hamid A Merchant, Céline Caillet, John Walsby-Tickle, Fay Probert, Pavel Matousek, Paul N Newton, Nicole Zitzmann, James S O McCullagh
Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening. NPJ vaccines 9 (1) (2024)
Chee Kin Then, Salome Paillas, Aliu Moomin, Mariya D Misheva, Rachel A Moir, Susan M Hay, David Bremner, Kristine S Roberts Nee Nellany, Ellen E Smith, Zeynab Heidari, Daniel Sescu, Xuedan Wang, Alejandro Suarez-Bonnet, Nadine Hay, Sarah L Murdoch, Ryoichi Saito, Elaina S R Collie-Duguid, Shirley Richardson, Simon Lawrence Priestnall, Joan M Wilson, Mahalakshmi Gurumurthy, Justine S Royle, Leslie M Samuel, George Ramsay, Katherine A Vallis, Kevin R Foster, James S O McCullagh, Anne E Kiltie
Dietary fibre supplementation enhances radiotherapy tumour control and alleviates intestinal radiation toxicity. Microbiome 12 (1) (2024)
Rebecca Clarke, Tehmina Bharucha, Benediktus Yohan Arman, Bevin Gangadharan, Laura Gomez Fernandez, Sara Mosca, Qianqi Lin, Kerlijn Van Assche, Robert Stokes, Susanna J Dunachie, Michael Deats, Hamid A Merchant, Céline Caillet, John Walsby-Tickle, Fay Probert, Pavel Matousek, Paul N Newton, Nicole Zitzmann, James S O McCullagh
Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening. NPJ vaccines 9 (1) (2024)
Chee Kin Then, Salome Paillas, Aliu Moomin, Mariya D Misheva, Rachel A Moir, Susan M Hay, David Bremner, Kristine S Roberts Nee Nellany, Ellen E Smith, Zeynab Heidari, Daniel Sescu, Xuedan Wang, Alejandro Suarez-Bonnet, Nadine Hay, Sarah L Murdoch, Ryoichi Saito, Elaina S R Collie-Duguid, Shirley Richardson, Simon Lawrence Priestnall, Joan M Wilson, Mahalakshmi Gurumurthy, Justine S Royle, Leslie M Samuel, George Ramsay, Katherine A Vallis, Kevin R Foster, James S O McCullagh, Anne E Kiltie
Dietary fibre supplementation enhances radiotherapy tumour control and alleviates intestinal radiation toxicity. Microbiome 12 (1) (2024)
Rebecca Clarke, Tehmina Bharucha, Benediktus Yohan Arman, Bevin Gangadharan, Laura Gomez Fernandez, Sara Mosca, Qianqi Lin, Kerlijn Van Assche, Robert Stokes, Susanna J Dunachie, Michael Deats, Hamid A Merchant, Céline Caillet, John Walsby-Tickle, Fay Probert, Pavel Matousek, Paul N Newton, Nicole Zitzmann, James S O McCullagh
Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening. NPJ vaccines 9 (1) (2024)
Kyung Chan Park, Nicholas T Crump, Niamh Louwman, Steve Krywawych, Yuen Jian Cheong, Iolanda Vendrell, Eleanor K Gill, Mala Gunadasa-Rohling, Kerrie L Ford, David Hauton, Marjorie Fournier, Elisabete Pires, Lydia Watson, Gerald Roseman, James Holder, Andreas Koschinski, Ricardo Carnicer, M Kate Curtis, Manuela Zaccolo, Alzbeta Hulikova, Roman Fischer, Holger B Kramer, James S O McCullagh, Sophie Trefely, Thomas A Milne, Pawel Swietach
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation. Nature cardiovascular research 2 (2023)
Kyung Chan Park, Nicholas T Crump, Niamh Louwman, Steve Krywawych, Yuen Jian Cheong, Iolanda Vendrell, Eleanor K Gill, Mala Gunadasa-Rohling, Kerrie L Ford, David Hauton, Marjorie Fournier, Elisabete Pires, Lydia Watson, Gerald Roseman, James Holder, Andreas Koschinski, Ricardo Carnicer, M Kate Curtis, Manuela Zaccolo, Alzbeta Hulikova, Roman Fischer, Holger B Kramer, James S O McCullagh, Sophie Trefely, Thomas A Milne, Pawel Swietach
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation. Nature cardiovascular research 2 (2023)
Vicki L Emms, Liam A Lewis, Lilla Beja, Natasha F A Bulman, Elisabete Pires, Frederick W Muskett, James S O McCullagh, Lonnie P Swift, Peter J McHugh, Richard J Hopkinson
N -Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells. Chemical science 14 (44) (2023)
Kyung Chan Park, Nicholas T Crump, Niamh Louwman, Steve Krywawych, Yuen Jian Cheong, Iolanda Vendrell, Eleanor K Gill, Mala Gunadasa-Rohling, Kerrie L Ford, David Hauton, Marjorie Fournier, Elisabete Pires, Lydia Watson, Gerald Roseman, James Holder, Andreas Koschinski, Ricardo Carnicer, M Kate Curtis, Manuela Zaccolo, Alzbeta Hulikova, Roman Fischer, Holger B Kramer, James S O McCullagh, Sophie Trefely, Thomas A Milne, Pawel Swietach
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation. Nature cardiovascular research 2 (2023)
Judith B Ngere, Kourosh H Ebrahimi, Rachel Williams, Elisabete Pires, John Walsby-Tickle, James S O McCullagh
Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. Analytical chemistry 95 (1) (2023)
Azrul Abdul Kadir, Brianna J Stubbs, Cher-Rin Chong, Henry Lee, Mark A Cole, Carolyn A Carr, David Hauton, James S O McCullagh, Rhys D Evans, Kieran Clarke
On the interdependence of ketone body oxidation, glycogen content, glycolysis and energy metabolism in the heart. The Journal of physiology (2023)
Stefania Morales-Herrera, Joris Jourquin, Frederic Coppé, Lorena Lopez-Galvis, Tom De Smet, Alaeddine Safi, Maria F Njo, Cara A Griffiths, John D Sidda, James S O McCullagh, Xiaochao Xue, Benjamin G Davis, Johan Van der Eycken, Matthew J Paul, Patrick Van Dijck, Tom Beeckman
Trehalose-6-phosphate signaling regulates lateral root formation in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America 120 (40) (2023)
Judith B Ngere, Kourosh H Ebrahimi, Rachel Williams, Elisabete Pires, John Walsby-Tickle, James S O McCullagh
Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. Analytical chemistry 95 (1) (2023)
Kyung Chan Park, Nicholas T Crump, Niamh Louwman, Steve Krywawych, Yuen Jian Cheong, Iolanda Vendrell, Eleanor K Gill, Mala Gunadasa-Rohling, Kerrie L Ford, David Hauton, Marjorie Fournier, Elisabete Pires, Lydia Watson, Gerald Roseman, James Holder, Andreas Koschinski, Ricardo Carnicer, M Kate Curtis, Manuela Zaccolo, Alzbeta Hulikova, Roman Fischer, Holger B Kramer, James S O McCullagh, Sophie Trefely, Thomas A Milne, Pawel Swietach
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation. Nature cardiovascular research 2 (2023)
Azrul Abdul Kadir, Brianna J Stubbs, Cher-Rin Chong, Henry Lee, Mark A Cole, Carolyn A Carr, David Hauton, James S O McCullagh, Rhys D Evans, Kieran Clarke
On the interdependence of ketone body oxidation,glycogen content, glycolysis and energy metabolism in the heart. The Journal of physiology (2023)
Judith B Ngere, Kourosh H Ebrahimi, Rachel Williams, Elisabete Pires, John Walsby-Tickle, James S O McCullagh
Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. Analytical chemistry 95 (1) (2023)
Kyung Chan Park, Nicholas T Crump, Niamh Louwman, Steve Krywawych, Yuen Jian Cheong, Iolanda Vendrell, Eleanor K Gill, Mala Gunadasa-Rohling, Kerrie L Ford, David Hauton, Marjorie Fournier, Elisabete Pires, Lydia Watson, Gerald Roseman, James Holder, Andreas Koschinski, Ricardo Carnicer, M Kate Curtis, Manuela Zaccolo, Alzbeta Hulikova, Roman Fischer, Holger B Kramer, James S O McCullagh, Sophie Trefely, Thomas A Milne, Pawel Swietach
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation. Nature cardiovascular research 2 (2023)
Judith B Ngere, Kourosh H Ebrahimi, Rachel Williams, Elisabete Pires, John Walsby-Tickle, James S O McCullagh
Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research. Analytical chemistry 95 (1) (2023)
Linyi Zhu, Pragash Kamalathevan, Lada A Koneva, Jadwiga Miotla Zarebska, Anastasios Chanalaris, Heba Ismail, Akira Wiberg, Michael T H Ng, Hayat Muhammad, John Walsby-Tickle, James S O McCullagh, Fiona E Watt, null null, Stephen N Sansom, Dominic Furniss, Matthew D Gardiner, Tonia L Vincent, Nick Riley, Michelle Spiteri, Ian McNab, Christopher Little, Lucy Cogswell, Paul Critchley, Henk Giele, Rebecca Shirley
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine 14 (676) (2022)
Linyi Zhu, Pragash Kamalathevan, Lada A Koneva, Jadwiga Miotla Zarebska, Anastasios Chanalaris, Heba Ismail, Akira Wiberg, Michael T H Ng, Hayat Muhammad, John Walsby-Tickle, James S O McCullagh, Fiona E Watt, null null, Stephen N Sansom, Dominic Furniss, Matthew D Gardiner, Tonia L Vincent, Nick Riley, Michelle Spiteri, Ian McNab, Christopher Little, Lucy Cogswell, Paul Critchley, Henk Giele, Rebecca Shirley
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine 14 (676) (2022)
Elizabeth Haythorne, Matthew Lloyd, John Walsby-Tickle, Andrei I Tarasov, Jonas Sandbrink, Idoia Portillo, Raul Terron Exposito, Gregor Sachse, Malgorzata Cyranka, Maria Rohm, Patrik Rorsman, James S O McCullagh, Frances M Ashcroft
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells. Nature communications 13 (1) (2022)
Linyi Zhu, Pragash Kamalathevan, Lada A Koneva, Jadwiga Miotla Zarebska, Anastasios Chanalaris, Heba Ismail, Akira Wiberg, Michael T H Ng, Hayat Muhammad, John Walsby-Tickle, James S O McCullagh, Fiona E Watt, null null, Stephen N Sansom, Dominic Furniss, Matthew D Gardiner, Tonia L Vincent, Nick Riley, Michelle Spiteri, Ian McNab, Christopher Little, Lucy Cogswell, Paul Critchley, Henk Giele, Rebecca Shirley
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine 14 (676) (2022)
Raphael Reinbold, Ingvild C Hvinden, Patrick Rabe, Ryan A Herold, Alina Finch, James Wood, Melissa Morgan, Maximillian Staudt, Ian J Clifton, Fraser A Armstrong, James S O McCullagh, Jo Redmond, Chiara Bardella, Martine I Abboud, Christopher J Schofield
Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nature communications 13 (1) (2022)
Linyi Zhu, Pragash Kamalathevan, Lada A Koneva, Jadwiga Miotla Zarebska, Anastasios Chanalaris, Heba Ismail, Akira Wiberg, Michael T H Ng, Hayat Muhammad, John Walsby-Tickle, James S O McCullagh, Fiona E Watt, null null, Stephen N Sansom, Dominic Furniss, Matthew D Gardiner, Tonia L Vincent, Nick Riley, Michelle Spiteri, Ian McNab, Christopher Little, Lucy Cogswell, Paul Critchley, Henk Giele, Rebecca Shirley
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine 14 (676) (2022)
Linyi Zhu, Pragash Kamalathevan, Lada A Koneva, Jadwiga Miotla Zarebska, Anastasios Chanalaris, Heba Ismail, Akira Wiberg, Michael T H Ng, Hayat Muhammad, John Walsby-Tickle, James S O McCullagh, Fiona E Watt, null null, Stephen N Sansom, Dominic Furniss, Matthew D Gardiner, Tonia L Vincent, Nick Riley, Michelle Spiteri, Ian McNab, Christopher Little, Lucy Cogswell, Paul Critchley, Henk Giele, Rebecca Shirley
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine 14 (676) (2022)
Linyi Zhu, Pragash Kamalathevan, Lada A Koneva, Jadwiga Miotla Zarebska, Anastasios Chanalaris, Heba Ismail, Akira Wiberg, Michael T H Ng, Hayat Muhammad, John Walsby-Tickle, James S O McCullagh, Fiona E Watt, null null, Stephen N Sansom, Dominic Furniss, Matthew D Gardiner, Tonia L Vincent, Nick Riley, Michelle Spiteri, Ian McNab, Christopher Little, Lucy Cogswell, Paul Critchley, Henk Giele, Rebecca Shirley
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science translational medicine 14 (676) (2022)
Shuang Liu, Martine I Abboud, Tobias John, Victor Mikhailov, Ingvild C Hvinden, John Walsby-Tickle, Xiao Liu, Ilaria Pettinati, Tom Cadoux-Hudson, James S O McCullagh, Christopher J Schofield
Roles of metal ions in the selective inhibition of oncogenic variants of isocitrate dehydrogenase 1. Communications biology 4 (1) (2021)
Johannes Gregor Matthias Rack, Qiang Liu, Valentina Zorzini, Jim Voorneveld, Antonio Ariza, Kourosh Honarmand Ebrahimi, Julia M Reber, Sarah C Krassnig, Dragana Ahel, Gijsbert A van der Marel, Aswin Mangerich, James S O McCullagh, Dmitri V Filippov, Ivan Ahel
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal. Nature communications 12 (1) (2021)
Thomas Cadoux-Hudson, Christopher J Schofield, James S O McCullagh
Isocitrate dehydrogenase gene variants in cancer and their clinical significance. Biochemical Society transactions (2021)
Kourosh Honarmand Ebrahimi, Jane Vowles, Cathy Browne, James S O McCullagh, William S James
ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD+ -dependent activity of enzymes to modulate metabolism. FEBS letters 594 (10) (2020)
John Walsby-Tickle, Joan Gannon, Ingvild C Hvinden, Chiara Bardella, Martine I Abboud, Areesha Nazeer, David Hauton, Elisabete Pires, Tom Cadoux-Hudson, Christopher J Schofield, James S O McCullagh
Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells. Communications biology 3 (1) (2020)
Daisheng Song, Bradleigh E Navalsky, Wei Guan, Cassandra Ingersoll, Tao Wang, Emanuele Loro, Lydia Eeles, Kyle B Matchett, Melanie J Percy, John Walsby-Tickle, James S O McCullagh, Reinhold J Medina, Tejvir S Khurana, Abigail W Bigham, Terence R Lappin, Frank S Lee
Tibetan PHD2, an allele with loss-of-function properties. Proceedings of the National Academy of Sciences of the United States of America 117 (22) (2020)
Kuo-Feng Hsu, Sarah E Wilkins, Richard J Hopkinson, Rok Sekirnik, Emily Flashman, Akane Kawamura, James S O McCullagh, Louise J Walport, Christopher J Schofield
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications. Epigenetics 16 (1) (2020)
Kourosh Honarmand Ebrahimi, Javier Gilbert Jaramillo, William S James, James S O McCullagh
Interferon-stimulated gene products as regulators of central carbon metabolism. The FEBS journal 288 (12) (2020)
Thibaut Deviese, Daniel Comeskey, James S O McCullagh, Christopher Bronk Ramsey, Thomas Higham
New protocol for compound-specific radiocarbon analysis of archaeological bones. Rapid communications in mass spectrometry : RCM 32 (5) (2018)