Purvesh Khatri

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 67

Top Topics

Immune Response

Top Venues

Nature immunology

Science translational medicine

Nature communications

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Christian A Choe, Johan O L Andreasson, Feriel Melaine, Wipapat Kladwang, Michelle J Wu, Fernando Portela, Roger Wellington-Oguri, John J Nicol, Hannah K Wayment-Steele, Michael Gotrik, Eterna Participants, Purvesh Khatri, William J Greenleaf, Rachel J Hagey
Compact RNA sensors for increasingly complex functions of multiple inputs. bioRxiv : the preprint server for biology (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology 25 (8) (2024)
Jason Nideffer, Maureen Ty, Michele Donato, John Rek, Richard Kajubi, Xuhuai Ji, Felistas Nankya, Kenneth Musinguzi, Kathleen Dantzler Press, Nora Yang, Kylie Camanag, Bryan Greenhouse, Moses R Kamya, Margaret E Feeney, Grant Dorsey, Paul J Utz, Bali Pulendran, Purvesh Khatri, Prasanna Jagannathan
Clinical immunity to malaria involves epigenetic reprogramming of innate immune cells. PNAS nexus 3 (8) (2024)
Jason Nideffer, Maureen Ty, Michele Donato, John Rek, Richard Kajubi, Xuhuai Ji, Felistas Nankya, Kenneth Musinguzi, Kathleen Dantzler Press, Nora Yang, Kylie Camanag, Bryan Greenhouse, Moses R Kamya, Margaret E Feeney, Grant Dorsey, Paul J Utz, Bali Pulendran, Purvesh Khatri, Prasanna Jagannathan
Clinical immunity to malaria involves epigenetic reprogramming of innate immune cells. PNAS nexus 3 (8) (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology 25 (8) (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology 25 (8) (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology 25 (8) (2024)
Christian A Choe, Johan O L Andreasson, Feriel Melaine, Wipapat Kladwang, Michelle J Wu, Fernando Portela, Roger Wellington-Oguri, John J Nicol, Hannah K Wayment-Steele, Michael Gotrik, Eterna Participants, Purvesh Khatri, William J Greenleaf, Rachel J Hagey
Compact RNA sensors for increasingly complex functions of multiple inputs. bioRxiv : the preprint server for biology (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology 25 (8) (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology 25 (8) (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Author Correction: Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology (2024)
Christian A Choe, Johan O L Andreasson, Feriel Melaine, Wipapat Kladwang, Michelle J Wu, Fernando Portela, Roger Wellington-Oguri, John J Nicol, Hannah K Wayment-Steele, Michael Gotrik, Eterna Participants, Purvesh Khatri, William J Greenleaf, Rachel J Hagey
Compact RNA sensors for increasingly complex functions of multiple inputs. bioRxiv : the preprint server for biology (2024)
Meng Sun, Jolie M Phan, Nathan S Kieswetter, Huang Huang, Krystle K Q Yu, Malisa T Smith, Yiran E Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W Henry Boom, Thomas R Hawn, Catherine M Stein, Harriet Mayanja-Kizza, Mark M Davis, Chetan Seshadri
Specific CD4 + T cell phenotypes associate with bacterial control in people who 'resist' infection with Mycobacterium tuberculosis. Nature immunology (2024)
Jason Nideffer, Maureen Ty, Michele Donato, John Rek, Richard Kajubi, Xuhuai Ji, Felistas Nankya, Kenneth Musinguzi, Kathleen Dantzler Press, Nora Yang, Kylie Camanag, Bryan Greenhouse, Moses R Kamya, Margaret E Feeney, Grant Dorsey, Paul J Utz, Bali Pulendran, Purvesh Khatri, Prasanna Jagannathan
Clinical immunity to malaria involves epigenetic reprogramming of innate immune cells. PNAS nexus 3 (8) (2024)
Roshani Sinha, Mai Dvorak, Ananthakrishnan Ganesan, Larry Kalesinskas, Charlotte M Niemeyer, Christian Flotho, Kathleen M Sakamoto, Norman Lacayo, Rachana Vinay Patil, Rhonda Perriman, Alma-Martina Cepika, Yunying Lucy Liu, Alex Kuo, Paul J Utz, Purvesh Khatri, Alice Bertaina
Epigenetic Profiling of PTPN11 Mutant JMML Hematopoietic Stem and Progenitor Cells Reveals an Aberrant Histone Landscape. Cancers 15 (21) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Oihane Erice, Shruthi Narayanan, Iker Feliu, Rodrigo Entrialgo-Cadierno, Antonia Malinova, Caterina Vicentini, Elisabeth Guruceaga, Pietro Delfino, Marija Trajkovic-Arsic, Haritz Moreno, Karmele Valencia, Ester Blanco, Irati Macaya, Daniel Öhlund, Purvesh Khatri, Fernando Lecanda, Aldo Scarpa, Jens Thomas Siveke, Vincenzo Corbo, Mariano Ponz-Sarvisé, Silvestre Vincent
Lamc2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Maryam Shojaei, Uan-I Chen, Uros Midic, Simone Thair, Sally Teoh, Anthony McLean, Timothy E Sweeney, Matthew Thompson, Oliver Liesenfeld, Purvesh Khatri, Benjamin Tang
Multi-site validation of a host response signature for predicting likelihood of bacterial and viral infections in patients with suspected influenza. European journal of clinical investigation (2023)
Rushika Pandya, Yudong D He, Timothy E Sweeney, Yehudit Hasin-Brumshtein, Purvesh Khatri
A machine learning classifier using 33 host immune response mRNAs accurately distinguishes viral and non-viral acute respiratory illnesses in nasal swab samples. Genome medicine 15 (1) (2023)
Oihane Erice, Shruthi Narayanan, Iker Feliu, Rodrigo Entrialgo-Cadierno, Antonia Malinova, Caterina Vicentini, Elisabeth Guruceaga, Pietro Delfino, Marija Trajkovic-Arsic, Haritz Moreno, Karmele Valencia, Ester Blanco, Irati Macaya, Daniel Öhlund, Purvesh Khatri, Fernando Lecanda, Aldo Scarpa, Jens Thomas Siveke, Vincenzo Corbo, Mariano Ponz-Sarvisé, Silvestre Vincent
LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (6) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
James R Heath, Daniel G Chen, Jingyi Xie, Jongchan Choi, Rachel H Ng, Rongyu Zhang, Sarah Li, Rick Edmark, Hong Zheng, Benjamin D Solomon, Katie M Campbell, Egmidio Medina, Antoni Ribas, Purvesh Khatri, Lewis L Lanier, Philip Mease, Jason D Goldman, Yapeng Su
An NKG2A biased immune response confers protection for infection, autoimmune disease, and cancer. Research square (2023)
Irati Macaya, Marta Roman, Connor Welch, Rodrigo Entrialgo-Cadierno, Marina Salmon, Alba Santos, Iker Feliu, Joanna R Kovalski, Ines Lopez, Maria Rodriguez-Remirez, Sara Palomino-Echeverria, Shane M Lonfgren, Macarena Ferrero, Silvia Calabuig, Iziar A Ludwig, David Lara-Astiaso, Eloísa Jantus-Lewintre, Elisabeth Guruceaga, Shruthi Narayanan, Mariano Ponz-Sarvisé, Antonio Pineda-Lucena, Fernando Lecanda, Davide Ruggero, Purvesh Khatri, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Irene Ferrer, Luis Paz-Ares, Matthias Drosten, Mariano Barbacid, Ignacio Gil-Bazo, Silvestre Vincent
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer. Nature communications 14 (1) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Oihane Erice, Shruthi Narayanan, Iker Feliu, Rodrigo Entrialgo-Cadierno, Antonia Malinova, Caterina Vicentini, Elisabeth Guruceaga, Pietro Delfino, Marija Trajkovic-Arsic, Haritz Moreno, Karmele Valencia, Ester Blanco, Irati Macaya, Daniel Öhlund, Purvesh Khatri, Fernando Lecanda, Aldo Scarpa, Jens Thomas Siveke, Vincenzo Corbo, Mariano Ponz-Sarvisé, Silvestre Vincent
LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (6) (2023)
Burcu Ayoglu, Michele Donato, Daniel E Furst, Leslie J Crofford, Ellen Goldmuntz, Lynette Keyes-Elstein, Judith A James, Susan Macwana, Maureen D Mayes, Peter McSweeney, Richard A Nash, Keith M Sullivan, Beverly Welch, Ashley Pinckney, Rong Mao, Lorinda Chung, Purvesh Khatri, Paul J Utz
Characterising the autoantibody repertoire in systemic sclerosis following myeloablative haematopoietic stem cell transplantation. Annals of the rheumatic diseases (2023)
Maryam Shojaei, Uan-I Chen, Uros Midic, Simone Thair, Sally Teoh, Anthony McLean, Timothy E Sweeney, Matthew Thompson, Oliver Liesenfeld, Purvesh Khatri, Benjamin Tang
Multisite validation of a host response signature for predicting likelihood of bacterial and viral infections in patients with suspected influenza. European journal of clinical investigation (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Maureen Ty, Shenghuan Sun, Perri C Callaway, John Rek, Kathleen Dantzler Press, Kattria van der Ploeg, Jason Nideffer, Zicheng Hu, Sandy Klemm, William J Greenleaf, Michele Donato, Stephen Tukwasibwe, Emmanuel Arinaitwe, Felistas Nankya, Kenneth Musinguzi, Dean Andrew, Lauren de la Parte, Diego Martinez Mori, Savannah Nicole Lewis, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Catherine A Blish, Paul J Utz, Purvesh Khatri, Grant Dorsey, Moses Kamya, Michelle J Boyle, Margaret E Feeney, Isaac Ssewanyana, Prasanna Jagannathan
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria. Science translational medicine 15 (680) (2023)
Prabhu S Arunachalam, Madeleine K D Scott, Thomas Hagan, Chunfeng Li, Yupeng Feng, Florian Wimmers, Lilit Grigoryan, Meera Trisal, Venkata-Viswanadh Edara, Lilin Lai, Sarah Esther Chang, Allan Feng, Shaurya Dhingra, Mihir Shah, Alexandra S Lee, Sharon Chinthrajah, Sayantani B Sindher, Venkata Vamsee Aditya Mallajosyula, Fei Gao, Natalia Sigal, Sangeeta Kowli, Sheena Gupta, Kathryn Pellegrini, Gregory K Tharp, Sofia Maysel-Auslender, Sydney Hamilton, Hadj Aoued, Kevin Hrusovsky, Mark Roskey, Steven E Bosinger, Holden T Maecker, Scott D Boyd, Mark M Davis, Paul J Utz, Mehul S Suthar, Purvesh Khatri, Kari Christine Nadeau, Bali Pulendran
Addendum: Systems vaccinology of the BNT162b2 mRNA vaccine in humans. Nature (2023)
Melodi Anahtar, Leslie W Chan, Henry Ko, Aditya Rao, Ava P Soleimany, Purvesh Khatri, Sangeeta N Bhatia
Host protease activity classifies pneumonia etiology. Proceedings of the National Academy of Sciences of the United States of America 119 (25) (2022)
Rachel J Hagey, Menashe Elazar, Edward A Pham, Siqi Tian, Lily Ben-Avi, Claire Bernardin-Souibgui, Matthew F Yee, Fernando R Moreira, Meirav Vilan Rabinovitch, Rita M Meganck, Benjamin Fram, Aimee Beck, Scott A Gibson, Grace Lam, Josephine Devera, Wipapat Kladwang, Khanh Nguyen, Anming Xiong, Steven Schaffert, Talia Avisar, Ping Liu, Arjun Rustagi, Carl J Fichtenbaum, Phillip S Pang, Purvesh Khatri, Chien-Te Kent Tseng, Jeffery K Taubenberger, Catherine A Blish, Brett L Hurst, Timothy P Sheahan, Rachel J Hagey, Jeffrey S Glenn
Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2. Nature medicine 28 (9) (2022)
Lawrence Bai, Denis Dermadi, Laurynas Kalesinskas, Mai Dvorak, Sarah E Chang, Ananthakrishnan Ganesan, Samuel J S Rubin, Alex Kuo, Peggie Cheung, Michele Donato, Paul J Utz, Aida Habtezion, Purvesh Khatri
Mass-cytometry-based quantitation of global histone post-translational modifications at single-cell resolution across peripheral immune cells in IBD. Journal of Crohn's & colitis (2022)
Lawrence Bai, Denis Dermadi, Laurynas Kalesinskas, Mai Dvorak, Sarah E Chang, Ananthakrishnan Ganesan, Samuel J S Rubin, Alex Kuo, Peggie Cheung, Michele Donato, Paul J Utz, Aida Habtezion, Purvesh Khatri
Mass-cytometry-based quantitation of global histone post-translational modifications at single-cell resolution across peripheral immune cells in IBD. Journal of Crohn's & colitis (2022)
Afroza Akter, Tasnuva Ahmed, Imam Tauheed, Marjahan Akhtar, Sadia Isfat Ara Rahman, Fatema Khaton, Faisal Ahmmed, Jannatul Ferdous, Mokibul Hassan Afrad, Zannat Kawser, Mohabbat Hossain, Rabeya Khondaker, Mohammad Abul Hasnat, Mostafa Aziz Sumon, Asif Rashed, Shuvro Ghosh, Stephen B Calderwood, Richelle C Charles, Edward T Ryan, Purvesh Khatri, Holden Terry Maecker, Gerlinde Obermoser, Bali Pulendran, John D Clemens, Sayera Banu, Tahmina Shirin, Regina C LaRocque, Jason B Harris, Taufiqur Rahman Bhuiyan, Fahima Chowdhury, Firdausi Qadri
Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, Bangladesh. PLoS neglected tropical diseases 16 (1) (2022)
Guangbo Chen, Gail H Deutsch, Grant S Schulert, Hong Zheng, SoRi Jang, Bruce C Trapnell, Pui Y Lee, Claudia Macaubas, Katherine Ho, Corinne Schneider, Vivian E Saper, Adriana Almeida de Jesus, Mark A Krasnow, Alexei Grom, Raphaela Goldbach Mansky, Purvesh Khatri, Elizabeth D Mellins, Scott W Canna
Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis. Arthritis & rheumatology (Hoboken, N.J.) 74 (7) (2022)
Erin F McCaffrey, Michele Donato, Leeat Keren, Zhenghao Chen, Alea Delmastro, Megan Burke Fitzpatrick, Sanjana Gupta, Noah F Greenwald, Alex Baranski, William Graf, Rashmi Kumar, Marc Bosse, Christine Camacho Fullaway, Pratista K Ramdial, Erna Forgó, Vladimir Jojic, David Van Valen, Smriti Mehra, Shabaana Abdul Khader, Sean C Bendall, Matt van de Rijn, Daniel Kalman, Deepak Kaushal, Robert L Hunter, Niaz Banaei, Adrie J C Steyn, Purvesh Khatri, R Michael Angelo
The immunoregulatory landscape of human tuberculosis granulomas. Nature immunology 23 (2) (2022)
Yiran E Liu, Sirle Saul, Aditya Manohar Rao, Makeda Lucretia Robinson, Olga Lucia Agudelo Rojas, Ana Maria Sanz, Michelle Verghese, Daniel Solis, Mamdouh Sibai, Chun Hong Huang, Malaya Kumar Sahoo, Rosa Margarita Gelvez, Nathalia Bueno, Maria Isabel Estupiñan Cardenas, Luis Angel Villar Centeno, Elsa Marina Rojas Garrido, Fernando Rosso, Michele Donato, Benjamin A Pinsky, Shirit Einav, Purvesh Khatri
An 8-gene machine learning model improves clinical prediction of severe dengue progression. Genome medicine 14 (1) (2022)
Kalani Ratnasiri, Aaron J Wilk, Madeline J Lee, Purvesh Khatri, Catherine A Blish
Single-cell RNA-seq methods to interrogate virus-host interactions. Seminars in immunopathology (2022)
Laurynas Kalesinskas, Sanjana Gupta, Purvesh Khatri
Increasing reproducibility, robustness, and generalizability of biomarker selection from meta-analysis using Bayesian methodology. PLoS computational biology 18 (6) (2022)
Chunfeng Li, Audrey Lee, Lilit Grigoryan, Prabhu S Arunachalam, Madeleine K D Scott, Meera Trisal, Florian Wimmers, Mrinmoy Sanyal, Payton A Weidenbacher, Yupeng Feng, Julia Z Adamska, Erika Valore, Yanli Wang, Rohit Verma, Noah Reis, Diane Dunham, Ruth O'Hara, Helen Park, Wei Luo, Alexander D Gitlin, Peter Kim, Purvesh Khatri, Kari Christine Nadeau, Bali Pulendran
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine. Nature immunology 23 (4) (2022)
Prabhu S Arunachalam, Madeleine K D Scott, Thomas Hagan, Chunfeng Li, Yupeng Feng, Florian Wimmers, Lilit Grigoryan, Meera Trisal, Venkata-Viswanadh Edara, Lilin Lai, Sarah Esther Chang, Allan Feng, Shaurya Dhingra, Mihir Shah, Alexandra S Lee, Sharon Chinthrajah, Sayantani B Sindher, Venkata Vamsee Aditya Mallajosyula, Fei Gao, Natalia Sigal, Sangeeta Kowli, Sheena Gupta, Kathryn Pellegrini, Gregory K Tharp, Sofia Maysel-Auslender, Sydney Hamilton, Hadj Aoued, Kevin Hrusovsky, Mark Roskey, Steven E Bosinger, Holden T Maecker, Scott D Boyd, Mark M Davis, Paul J Utz, Mehul S Suthar, Purvesh Khatri, Kari Christine Nadeau, Bali Pulendran
Systems vaccinology of the BNT162b2 mRNA vaccine in humans. Nature 596 (7872) (2021)
Diederik E van der Feen, Guido P L Bossers, Quint A J Hagdorn, Jan Renier Moonen, Kondababu Kurakula, Robert Szulcek, James Chappell, Francesco Vallania, Michele Donato, Klaas Kok, Jaskaren S Kohli, Arjen H Petersen, Tom van Leusden, Marco Demaria, Marie-José T H Goumans, Rudolf A de Boer, Purvesh Khatri, Marlene Rabinovitch, Rolf M F Berger, Beatrijs Bartelds
Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Science translational medicine 12 (554) (2021)
Lauren E Higdon, Steven Schaffert, Rachel H Cohen, Maria E Montez-Rath, Marc Lucia, Naresha Saligrama, Kenneth B Margulies, Olivia M Martinez, Jane C Tan, Mark M Davis, Purvesh Khatri, Jonathan S Maltzman
Functional Consequences of Memory Inflation after Solid Organ Transplantation. Journal of immunology (Baltimore, Md. : 1950) 207 (8) (2021)
Cesar J Lopez Angel, Edward A Pham, Huixun Du, Francesco Vallania, Benjamin J Fram, Kevin Perez, Thai Nguyen, Yael Rosenberg-Hasson, Aijaz Ahmed, Cornelia L Dekker, Philip M Grant, Purvesh Khatri, Holden T Maecker, Jeffrey S Glenn, Mark M Davis, David Furman
Signatures of immune dysfunction in HIV and HCV infection share features with chronic inflammation in aging and persist after viral reduction or elimination. Proceedings of the National Academy of Sciences of the United States of America 118 (14) (2021)
Lauren E Higdon, Steven Schaffert, Huang Huang, Maria E Montez-Rath, Marc Lucia, Alokkumar Jha, Naresha Saligrama, Kenneth B Margulies, Olivia M Martinez, Mark M Davis, Purvesh Khatri, Jonathan S Maltzman
Evolution of Cytomegalovirus-Responsive T Cell Clonality following Solid Organ Transplantation. Journal of immunology (Baltimore, Md. : 1950) 207 (8) (2021)
Suraj Sakaram, Yehudit Hasin-Brumshtein, Purvesh Khatri, Yudong D He, Timothy E Sweeney
A Multi-mRNA Prognostic Signature for Anti-TNFα Therapy Response in Patients with Inflammatory Bowel Disease. Diagnostics (Basel, Switzerland) 11 (10) (2021)
Mingxia Gu, Michele Donato, Minzhe Guo, Neil Wary, Yifei Miao, Shuai Mao, Toshie Saito, Shoichiro Otsuki, Lingli Wang, Rebecca L Harper, Silin Sa, Purvesh Khatri, Marlene Rabinovitch
iPSC-endothelial cell phenotypic drug screening and in silico analyses identify tyrphostin-AG1296 for pulmonary arterial hypertension. Science translational medicine 13 (592) (2021)
Peggie Cheung, Steven Schaffert, Sarah E Chang, Mai Dvorak, Michele Donato, Claudia Macaubas, Mariko H Foecke, Tie-Mei Li, Lichao Zhang, John P Coan, Grant S Schulert, Alexei A Grom, Lauren A Henderson, Peter A Nigrovic, Joshua E Elias, Or Gozani, Elizabeth D Mellins, Purvesh Khatri, Paul J Utz, Alex J Kuo
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. Nature immunology 22 (6) (2021)
Kerui Peng, Yana Safonova, Mikhail Shugay, Alice B Popejoy, Oscar L Rodriguez, Felix Breden, Petter Brodin, Amanda M Burkhardt, Carlos Bustamante, Van-Mai Cao-Lormeau, Martin M Corcoran, Darragh Duffy, Macarena Fuentes-Guajardo, Ricardo Fujita, Victor Greiff, Vanessa D Jönsson, Xiao Liu, Lluis Quintana-Murci, Maura Rossetti, Jianming Xie, Gur Yaari, Wei Zhang, Khalid Olajide Adekoya, Khalid O Adekoya, Rahaman A Ahmed, Wei-Chiao Chang, Clive Gray, Yusuke Nakamura, William D Lees, Purvesh Khatri, Houda Alachkar, Cathrine Scheepers, Corey T Watson, Gunilla B Karlsson Hedestam, Serghei Mangul
Diversity in immunogenomics: the value and the challenge. Nature methods 18 (6) (2021)
Lawrence Bai, Madeleine K D Scott, Ethan Steinberg, Laurynas Kalesinskas, Aida Habtezion, Nigam Haresh Shah, Purvesh Khatri
Computational drug repositioning of atorvastatin for ulcerative colitis. Journal of the American Medical Informatics Association : JAMIA 28 (11) (2021)
Prabhu S Arunachalam, Florian Wimmers, Chris Ka Pun Mok, Ranawaka A P M Perera, Madeleine Scott, Thomas Hagan, Natalia Sigal, Yupeng Feng, Laurel Bristow, Owen Tak-Yin Tsang, Dhananjay Wagh, John Coller, Kathryn L Pellegrini, Dmitri Kazmin, Ghina Alaaeddine, Wai Shing Leung, Jacky Man Chun Chan, Thomas Shiu Hong Chik, Chris Yau Chung Choi, Christopher Huerta, Michele Paine McCullough, Huibin Lv, Larry J Anderson, Srilatha Edupuganti, Amit A Upadhyay, Steven E Bosinger, Holden Terry Maecker, Purvesh Khatri, Nadine Rouphael, Joseph S Malik Peiris, Bali Pulendran
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans. Science (New York, N.Y.) 369 (6508) (2020)
Michael B Mayhew, Ljubomir Buturovic, Roland Luethy, Uros Midic, Andrew R Moore, Jonasel A Roque, Brian D Shaller, Tola Asuni, David Rawling, Melissa Remmel, Kirindi Choi, James Wacker, Purvesh Khatri, Angela J Rogers, Timothy E Sweeney
A generalizable 29-mRNA neural-network classifier for acute bacterial and viral infections. Nature communications 11 (1) (2020)
Eli M Cahan, Purvesh Khatri
Data Heterogeneity: The Enzyme to Catalyze Translational Bioinformatics? Journal of medical Internet research 22 (8) (2020)
Peggie Cheung, Purvesh Khatri, Paul J Utz, Alex J Kuo
Single-cell technologies - studying rheumatic diseases one cell at a time. Nature reviews. Rheumatology 15 (6) (2020)
Lauren E Higdon, Steven Schaffert, Purvesh Khatri, Jonathan S Maltzman
Single cell immune profiling in transplantation research. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 19 (5) (2019)
Francesco Vallania, Andrew Tam, Shane Lofgren, Steven Schaffert, Tej D Azad, Erika Bongen, Winston A Haynes, Meia Alsup, Michael Alonso, Mark Davis, Edgar Engleman, Purvesh Khatri
Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases. Nature communications 9 (1) (2018)
Aurelie Tomczak, Jonathan M Mortensen, Rainer Winnenburg, Charles Liu, Dominique T Alessi, Varsha Swamy, Francesco Vallania, Shane Lofgren, Winston A Haynes, Nigam Haresh Shah, Mark A Musen, Purvesh Khatri
Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations. Scientific reports 8 (1) (2018)
Winston A Haynes, Aurelie Tomczak, Purvesh Khatri
Gene annotation bias impedes biomedical research. Scientific reports 8 (1) (2018)
Timothy E Sweeney, Thanneer M Perumal, Ricardo Henao, Marshall Nichols, Judith A Howrylak, Augustine M Choi, Jesús F Bermejo-Martin, Raquel Almansa, Eduardo Tamayo, Emma E Davenport, Katie L Burnham, Charles J Hinds, Julian C Knight, Christopher W Woods, Stephen F Kingsmore, Geoffrey S Ginsburg, Hector R Wong, Grant P Parnell, Benjamin Tang, Lyle L Moldawer, Frederick E Moore, Larsson Omberg, Purvesh Khatri, Ephraim L Tsalik, Lara M Mangravite, Raymond J Langley
A community approach to mortality prediction in sepsis via gene expression analysis. Nature communications 9 (1) (2018)
Adrian Vallejo, Naiara Perurena, Elisabet Guruceaga, Pawel K Mazur, Susana Martinez-Canarias, Carolina Zandueta, Karmele Valencia, Andrea Arricibita, Dana Gwinn, Leanne C Sayles, Chen-Hua Chuang, Laura Guembe, Peter Bailey, David K Chang, Andrew Biankin, Mariano Ponz-Sarvise, Jesper B Andersen, Purvesh Khatri, Aline Bozec, E Alejandro Sweet-Cordero, Julien Sage, Fernando Lecanda, Silve Vicent
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nature communications 8 (2017)
Brooke A Napier, Sky W Brubaker, Timothy E Sweeney, Patrick James Monette, Greggory H Rothmeier, Nina A Gertsvolf, Andreas Puschnik, Jan E Carette, Purvesh Khatri, Denise M Monack
Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity. The Journal of experimental medicine 213 (11) (2016)
Timothy E Sweeney, Purvesh Khatri
Comprehensive Validation of the FAIM3:PLAC8 Ratio in Time-matched Public Gene Expression Data. American journal of respiratory and critical care medicine 192 (10) (2016)