Lars M Steinmetz (Lars Steinmetz)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 45

Top Topics

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Cellular and molecular life sciences : CMLS

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Christopher Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. Nature communications 15 (1) (2024)
Gernot Neumayer, Jessica L Torkelson, Shengdi Li, Kelly McCarthy, Hanson H Zhen, Madhuri Vangipuram, Marius Marc-Daniel Mader, Gulilat Gebeyehu, Taysir M Jaouni, Joanna Jackow-Malinowska, Avina Rami, Corey Hansen, Zongyou Guo, Sadhana Gaddam, Keri M Tate, Alberto Pappalardo, Lingjie Li, Grace M Chow, Kevin R Roy, Thuylinh Michelle Nguyen, Koji Tanabe, Patrick S McGrath, Amber Cramer, Anna Bruckner, Ganna Bilousova, Dennis R Roop, Jean Y Tang, Angela Christiano, Lars M Steinmetz, Marius Wernig, Anthony E Oro
A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. Nature communications 15 (1) (2024)
Benjamin A Story, Lars Velten, Gregor Mönke, Ahrmad Annan, Lars M Steinmetz
Mitoclone2: an R package for elucidating clonal structure in single-cell RNA-sequencing data using mitochondrial variants. NAR genomics and bioinformatics 6 (3) (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Chris Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. bioRxiv : the preprint server for biology (2024)
Evelyn Lattmann, Luca Räss, Marco Tognetti, Julia M Martínez Gómez, Valérie Lapaire, Roland Bruderer, Lukas Reiter, Yuehan Feng, Lars M Steinmetz, Mitchell Paul Levesque
Size-exclusion chromatography combined with DIA-MS enables deep proteome profiling of extracellular vesicles from melanoma plasma and serum. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Gernot Neumayer, Jessica L Torkelson, Shengdi Li, Kelly McCarthy, Hanson H Zhen, Madhuri Vangipuram, Marius Marc-Daniel Mader, Gulilat Gebeyehu, Taysir M Jaouni, Joanna Jackow-Malinowska, Avina Rami, Corey Hansen, Zongyou Guo, Sadhana Gaddam, Keri M Tate, Alberto Pappalardo, Lingjie Li, Grace M Chow, Kevin R Roy, Thuylinh Michelle Nguyen, Koji Tanabe, Patrick S McGrath, Amber Cramer, Anna Bruckner, Ganna Bilousova, Dennis R Roop, Jean Y Tang, Angela Christiano, Lars M Steinmetz, Marius Wernig, Anthony E Oro
A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. Nature communications 15 (1) (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Chris Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. bioRxiv : the preprint server for biology (2024)
Evelyn Lattmann, Luca Räss, Marco Tognetti, Julia M Martínez Gómez, Valérie Lapaire, Roland Bruderer, Lukas Reiter, Yuehan Feng, Lars M Steinmetz, Mitchell Paul Levesque
Size-exclusion chromatography combined with DIA-MS enables deep proteome profiling of extracellular vesicles from melanoma plasma and serum. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Kevin R Roy, Justin D Smith, Shengdi Li, Sibylle C Vonesch, Michelle Nguyen, Wallace T Burnett, Kevin M Orsley, Cheng-Sheng Lee, James E Haber, Robert P St Onge, Lars M Steinmetz
Dissecting quantitative trait nucleotides by saturation genome editing. bioRxiv : the preprint server for biology (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Christopher Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. Nature communications 15 (1) (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Christopher Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. Nature communications 15 (1) (2024)
Evelyn Lattmann, Luca Räss, Marco Tognetti, Julia M Martínez Gómez, Valérie Lapaire, Roland Bruderer, Lukas Reiter, Yuehan Feng, Lars M Steinmetz, Mitchell Paul Levesque
Size-exclusion chromatography combined with DIA-MS enables deep proteome profiling of extracellular vesicles from melanoma plasma and serum. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Chris Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. bioRxiv : the preprint server for biology (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Christopher Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. Nature communications 15 (1) (2024)
Kevin R Roy, Justin D Smith, Shengdi Li, Sibylle C Vonesch, Michelle Nguyen, Wallace T Burnett, Kevin M Orsley, Cheng-Sheng Lee, James E Haber, Robert P St Onge, Lars M Steinmetz
Dissecting quantitative trait nucleotides by saturation genome editing. bioRxiv : the preprint server for biology (2024)
Joseph J Hale, Takeshi Matsui, Ilan Goldstein, Martin N Mullis, Kevin R Roy, Chris Ne Ville, Darach Miller, Charley Wang, Trevor Reynolds, Lars M Steinmetz, Sasha F Levy, Ian M Ehrenreich
Genome-scale analysis of interactions between genetic perturbations and natural variation. bioRxiv : the preprint server for biology (2024)
Evelyn Lattmann, Luca Räss, Marco Tognetti, Julia M Martínez Gómez, Valérie Lapaire, Roland Bruderer, Lukas Reiter, Yuehan Feng, Lars M Steinmetz, Mitchell Paul Levesque
Size-exclusion chromatography combined with DIA-MS enables deep proteome profiling of extracellular vesicles from melanoma plasma and serum. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Benjamin A Story, Lars Velten, Gregor Mönke, Ahrmad Annan, Lars M Steinmetz
Mitoclone2: an R package for elucidating clonal structure in single-cell RNA-sequencing data using mitochondrial variants. NAR genomics and bioinformatics 6 (3) (2024)
Gernot Neumayer, Jessica L Torkelson, Shengdi Li, Kelly McCarthy, Hanson H Zhen, Madhuri Vangipuram, Marius Marc-Daniel Mader, Gulilat Gebeyehu, Taysir M Jaouni, Joanna Jackow-Malinowska, Avina Rami, Corey Hansen, Zongyou Guo, Sadhana Gaddam, Keri M Tate, Alberto Pappalardo, Lingjie Li, Grace M Chow, Kevin R Roy, Thuylinh Michelle Nguyen, Koji Tanabe, Patrick S McGrath, Amber Cramer, Anna Bruckner, Ganna Bilousova, Dennis R Roop, Jean Y Tang, Angela Christiano, Lars M Steinmetz, Marius Wernig, Anthony E Oro
A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. Nature communications 15 (1) (2024)
Andreas R Gschwind, Kristy S Mualim, Alireza Karbalayghareh, Maya U Sheth, Kushal K Dey, Evelyn Jagoda, Ramil N Nurtdinov, Wang Xi, Anthony S Tan, Hank Jones, X Rosa Ma, David Yao, Joseph Nasser, Žiga Avsec, Benjamin T James, Muhammad Saad Shamim, Neva C Durand, Suhas S P Rao, Ragini Mahajan, Benjamin R Doughty, Kalina Andreeva, Jacob C Ulirsch, Kaili Fan, Elizabeth M Perez, Tri C Nguyen, David R Kelley, Hilary K Finucane, Jill E Moore, Nishigandha Phalke, Manolis Kellis, Michael C Bassik, Alkes L Price, Michael A Beer, Roderic Guigo, John A Stamatoyannopoulos, Erez Lieberman Aiden, William J Greenleaf, Christina S Leslie, Lars M Steinmetz, Anshul Kundaje, Jesse M Engreitz
An encyclopedia of enhancer-gene regulatory interactions in the human genome. bioRxiv : the preprint server for biology (2023)
Muhammad Tayyab, Donal Barrett, Gijs van Riel, Shujing Liu, Björn Reinius, Curt Scharfe, Peter Griffin, Lars M Steinmetz, Mehdi Javanmard, Vicent Pelechano
Digital assay for rapid electronic quantification of clinical pathogens using DNA nanoballs. Science advances 9 (36) (2023)
Markus Grosch, Laura Schraft, Adrian Chan, Leonie Küchenhoff, Kleopatra Rapti, Anne-Maud Ferreira, Julia Kornienko, Shengdi Li, Michael H Radke, Chiara Krämer, Sandra Clauder-Münster, Emerald Perlas, Johannes Backs, Michael Gotthardt, Christoph Dieterich, Maarten M G van den Hoogenhof, Dirk Grimm, Lars M Steinmetz
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy. Nature communications 14 (1) (2023)
S Andreas Johansson, Thierry Dulermo, Cosimo Jann, Justin D Smith, Anna Pryszlak, Georges Pignede, Daniel Schraivogel, Didier Colavizza, Thomas Desfougères, Christophe Rave, Alexander Farwick, Christoph A Merten, Kevin R Roy, Wu Wei, Lars M Steinmetz
Large scale microfluidic CRISPR screening for increased amylase secretion in yeast. Lab on a chip (2023)
Jonathan Bieler, Christian Pozzorini, Jessica Garcia, Alex Charles Tuck, Morgane Macheret, Adrian Willig, Sébastien Couraud, Xiaobin Xing, Philippe Menu, Lars M Steinmetz, Léa Payen, Zhenyu Xu
High-Throughput Nucleotide Resolution Predictions of Assay Limitations Increase the Reliability and Concordance of Clinical Tests. JCO clinical cancer informatics 5 (2022)
Marion Müller, Rose Eghbalian, Jes-Niels Boeckel, Karen S Frese, Jan Haas, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Maximilian K Lackner, Oguz F Tugrul, Thomas Ruppert, Rewati Tappu, Diana Martins Bordalo, Jasmin Marga Kneuer, Annika Piekarek, Sabine Herch, Sarah Schudy, Andreas Keller, Nadja Grammes, Cornelius Bischof, Anna Klinke, Margarida Cardoso-Moreira, Henrick Kaessmann, Hugo A Katus, Norbert Frey, Lars M Steinmetz, Benjamin Meder
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart. Nature communications 13 (1) (2022)
Aaron N Brooks, Amanda L Hughes, Sandra Clauder-Münster, Leslie A Mitchell, Jef D Boeke, Lars M Steinmetz
Transcriptional neighborhoods regulate transcript isoform lengths and expression levels. Science (New York, N.Y.) 375 (6584) (2022)
Jing Li, Maxim E Zaslavsky, Yapeng Su, Jing Guo, Michael J Sikora, Vincent van Unen, Asbjørn O Christophersen, Shin-Heng Chiou, Liang Chen, Jiefu Li, Xuhuai Ji, Julie Wilhelmy, Alana M McSween, Brad A Palanski, Venkata Vamsee Aditya Mallajosyula, Nathan A Bracey, Gopal Krishna R Dhondalay, Kartik Bhamidipati, Joy Pai, Lucas B Kipp, Jeffrey E Dunn, Stephen L Hauser, Jorge R Oksenberg, Ansuman T Satpathy, William H Robinson, Cornelia L Dekker, Lars M Steinmetz, Chaitan Khosla, Paul J Utz, Ludvig M Sollid, Yueh-Hsiu Chien, James R Heath, Nielsen Q Fernandez-Becker, Kari Christine Nadeau, Naresha Saligrama, Mark M Davis
KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science (New York, N.Y.) 376 (6590) (2022)
David C Lennermann, Mark E Pepin, Markus Grosch, Laura Konrad, Elena Kemmling, Joshua Hartmann, Janica L Nolte, Sandra Clauder-Münster, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Jan Haas, Benjamin Meder, Malou van den Boogaard, Ahmad S Amin, Matthias Dewenter, Marcus Krüger, Lars M Steinmetz, Johannes Backs, Maarten M G van den Hoogenhof
Deep phenotyping of two preclinical mouse models and a cohort of RBM20 mutation carriers reveals no sex-dependent disease severity in RBM20 cardiomyopathy. American journal of physiology. Heart and circulatory physiology 323 (6) (2022)
Krishnaprasad G Nandanan, Sagar Salim, Ajith V Pankajam, Miki Shinohara, Gen Lin, Parijat Chakraborty, Amamah Farnaz, Lars M Steinmetz, Akira Shinohara, Koodali T Nishant
Regulation of Msh4-Msh5 association with meiotic chromosomes in budding yeast. Genetics 219 (2) (2022)
Jason A Carter, Léonie Strömich, Matthew Peacey, Sarah R Chapin, Lars Velten, Lars M Steinmetz, Benedikt Brors, Sheena Pinto, Hannah V Meyer
Transcriptomic diversity in human medullary thymic epithelial cells. Nature communications 13 (1) (2022)
Daniel Schraivogel, Terra M Kuhn, Benedikt Rauscher, Marta Rodríguez-Martínez, Malte Paulsen, Keegan Owsley, Aaron Middlebrook, Christian Tischer, Beáta Ramasz, Diana Ordoñez-Rueda, Martina Dees, Sara Cuylen-Haering, Eric Diebold, Lars M Steinmetz
High-speed fluorescence image-enabled cell sorting. Science (New York, N.Y.) 375 (6578) (2022)
Hamish W King, Kristen L Wells, Zohar Shipony, Arwa S Kathiria, Lisa E Wagar, Caleb A Lareau, Nara Orban, Robson Capasso, Mark M Davis, Lars M Steinmetz, Louisa Katherine James, William J Greenleaf
Integrated single-cell transcriptomics and epigenomics reveals strong germinal center-associated etiology of autoimmune risk loci. Science immunology 6 (64) (2021)
Chenchen Zhu, Jingyan Wu, Han Sun, Francesca Briganti, Benjamin Meder, Wu Wei, Lars M Steinmetz
Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes. Nature communications 12 (1) (2021)
Jing Li, Maxim E Zaslavsky, Yapeng Su, Michael J Sikora, Vincent van Unen, Asbjørn O Christophersen, Shin-Heng Chiou, Liang Chen, Jiefu Li, Xuhuai Ji, Julie Wilhelmy, Alana M McSween, Brad A Palanski, Venkata Vamsee Aditya Mallajosyula, Gopal Krishna R Dhondalay, Kartik Bhamidipati, Joy Pai, Lucas B Kipp, Jeffrey E Dunn, Stephen L Hauser, Jorge R Oksenberg, Ansuman T Satpathy, William H Robinson, Lars M Steinmetz, Chaitan Khosla, Paul J Utz, Ludvig M Sollid, James R Heath, Nielsen Q Fernandez-Becker, Kari Christine Nadeau, Naresha Saligrama, Mark M Davis
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19. bioRxiv : the preprint server for biology (2021)
Erwei Zuo, Yi-Di Sun, Wu Wei, Tanglong Yuan, Wenqin Ying, Hao Sun, Liyun Yuan, Lars M Steinmetz, Yixue Li, Hui Yang
GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos. Nature protocols 15 (9) (2020)
Jay W Schneider, Saji Oommen, Muhammad Yasir Qureshi, Sean C Goetsch, David Randall Pease, Rhianna S Sundsbak, Wei Guo, Mingming Sun, Hanice Sun, Hidehito Kuroyanagi, Dennis A Webster, Alexander W Coutts, Kimberly A Holst, Brooks S Edwards, Nikolas Newville, Matthew A Hathcock, Tamene Melkamu, Francesca Briganti, Wu Wei, Maria Grazia Romanelli, Scott C Fahrenkrug, Jonathan R Nitschke, Timothy M Olson, Lars M Steinmetz, Daniel F Carlson, Timothy J Nelson, null null
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs. Nature medicine 26 (11) (2020)
Daniel Schraivogel, Andreas R Gschwind, Jennifer H Milbank, Daniel R Leonce, Petra Jakob, Lukas Mathur, Jan O Korbel, Christoph A Merten, Lars Velten, Lars M Steinmetz
Targeted Perturb-seq enables genome-scale genetic screens in single cells. Nature methods 17 (6) (2020)
Kristen L Wells, Corey N Miller, Andreas R Gschwind, Wu Wei, Jonah D Phipps, Mark S Anderson, Lars M Steinmetz
Combined transient ablation and single-cell RNA-sequencing reveals the development of medullary thymic epithelial cells. eLife 9 (2020)
Erwei Zuo, Yi-Di Sun, Wu Wei, Tanglong Yuan, Wenqin Ying, Hao Sun, Liyun Yuan, Lars M Steinmetz, Yi-Xue Li, Hui Yang
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos. Science (New York, N.Y.) 364 (6437) (2019)
Mariona Nadal-Ribelles, Saiful Islam, Wu Wei, Pablo Latorre, Michelle Nguyen, Eulalia de Nadal, Francesc Posas, Lars M Steinmetz
Sensitive high-throughput single-cell RNA-seq reveals within-clonal transcript correlations in yeast populations. Nature microbiology 4 (4) (2019)
Chiara Baccin, Jude Al-Sabah, Lars Velten, Patrick Michael Helbling, Florian Grünschläger, Pablo Hernández-Malmierca, Cesar Nombela-Arrieta, Lars M Steinmetz, Flavia Carla Meotti, Simon Haas
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization. Nature cell biology 22 (1) (2019)
Sivan Kaminski Strauss, Dvir Schirman, Ghil Jona, Aaron N Brooks, Aditya M Kunjapur, Alex N Nguyen Ba, Alice Flint, Andras Solt, Andreas Mershin, Atray Dixit, Avihu H Yona, Bálint Csörgő, Bede Phillip Busby, Bianca P Hennig, Csaba Pál, Daniel Schraivogel, Daniel Schultz, David G Wernick, Deepa Agashe, Dikla Levi, Dmitry Zabezhinsky, Dor Russ, Ehud Sass, Einat Tamar, Elad Herz, Emmanuel D Levy, George M Church, Idan Yelin, Iftach Nachmann, Jeffrey E Gerst, Joseph M Georgeson, Katarzyna P Adamala, Lars M Steinmetz, Marc Rübsam, Markus Ralser, Michael Klutstein, Michael M Desai, Nilima Walunjkar, Ning Yin, Noa Aharon Hefetz, Noah Jakimo, Olga Snitser, Omri Adini, Prashant Kumar, Rachel Soo Hoo Smith, Razi Zeidan, Ronen Hazan, Roni Rak, Roy Kishony, Shannon Johnson, Shira Nouriel, Sibylle C Vonesch, Simmie Foster, Tal Dagan, Tanita Wein, Thrasyvoulos Karydis, Timothy M Wannier, Timothy Stiles, Viridiana Olin-Sandoval, William F Mueller, Yinon M Bar-On, Orna Dahan, Yitzhak Pilpel
Evolthon: A community endeavor to evolve lab evolution. PLoS biology 17 (3) (2019)
Wu Wei, Bianca P Hennig, Jingwen Wang, Yujie Zhang, Ilaria Piazza, Yerma P Sanchez, Christophe D Chabbert, Sophie H Adjalley, Lars M Steinmetz, Vicent Pelechano
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast. Genome research 29 (12) (2019)
Zhicong Huang, Erman Ayday, Huang Lin, Raeka S Aiyar, Adam Molyneaux, Zhenyu Xu, Jacques Fellay, Lars M Steinmetz, Jean-Pierre Hubaux
A privacy-preserving solution for compressed storage and selective retrieval of genomic data. Genome research 26 (12) (2016)
Saumya Gupta, Aparna Radhakrishnan, Rachana Nitin, Pandu Raharja-Liu, Gen Lin, Lars M Steinmetz, Julien Gagneur, Himanshu Sinha
Meiotic Interactors of a Mitotic Gene TAO3 Revealed by Functional Analysis of its Rare Variant. G3 (Bethesda, Md.) 6 (8) (2016)