Karen Blyth

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 67

Top Venues

Nature communications

Nature cancer

Science advances

The EMBO journal

CRUK Beatson Institute

University of Glasgow (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

CRUK Beatson Institute

United Kingdom

Senior Staff Scientist

University of Glasgow

United Kingdom

Honorary Senior Lecturer

CRUK Beatson Institute

United Kingdom

Head :: Transgenic Models Laboratory

University of Glasgow

United Kingdom

Post-doctoral research fellow

University of Glasgow

United Kingdom

Post-doctoral research assistant

University of Glasgow

United Kingdom

Research Assistant

Education History

University of Glasgow

United Kingdom

PHD

University of Glasgow

United Kingdom

BSC :: Biochemistry

Publications

Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer 5 (4) (2024)
Robert Wiesheu, Sarah C Edwards, Ann Hedley, Holly Hall, Marie Tosolini, Marcelo Gregorio Filho Fares da Silva, Nital Sumaria, Suzanne M Castenmiller, Leyma Wardak, Yasmin Optaczy, Amy Lynn, David G Hill, Alan J Hayes, Jodie Hay, Anna Kilbey, Robin Shaw, Declan Whyte, Peter J Walsh, Alison M Michie, Gerard J Graham, Anand Manoharan, Christina Halsey, Karen Blyth, Monika C Wolkers, Crispin Miller, Daniel J Pennington, Gareth W Jones, Jean-Jacques Fournie, Vasileios Bekiaris, Seth B Coffelt
IL-27 maintains cytotoxic Ly6C + γδ T cells that arise from immature precursors. The EMBO journal 43 (14) (2024)
Alice Santi, Emily J Kay, Lisa J Neilson, Lynn McGarry, Sergio Lilla, Margaret Mullin, Nikki R Paul, Frédéric Fercoq, Grigorios Koulouras, Giovanny Rodriguez Blanco, Dimitris Athineos, Susan Mason, Mark Hughes, Gemma Thomson, Yann Kieffer, Colin Nixon, Karen Blyth, Fatima Mechta-Grigoriou, Leo M Carlin, Sara R Zanivan
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science signaling 17 (827) (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer 5 (4) (2024)
Piotr Dzien, Ximena Raffo Iraolagoitia, Stephanie May, David Stevenson, Lynn McGarry, Dmitry Soloviev, Gavin Brown, Colin Nixon, Chrysa Kapeni, Maike De La Roche, Karen Blyth, Scott Lyons, Thomas Bird, Douglas Strathdee, Gilbert O Fruhwirth, Leo Carlin, David Y Lewis
Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system. Research square (2024)
Florian J Bock, Egor Sedov, Elle Koren, Anna L Koessinger, Catherine Cloix, Désirée Zerbst, Dimitris Athineos, Jayanthi Anand, Kirsteen J Campbell, Karen Blyth, Yaron Fuchs, Stephen W G Tait
Author Correction: Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature communications 15 (1) (2024)
Robert Wiesheu, Sarah C Edwards, Ann Hedley, Holly Hall, Marie Tosolini, Marcelo Gregorio Filho Fares da Silva, Nital Sumaria, Suzanne M Castenmiller, Leyma Wardak, Yasmin Optaczy, Amy Lynn, David G Hill, Alan J Hayes, Jodie Hay, Anna Kilbey, Robin Shaw, Declan Whyte, Peter J Walsh, Alison M Michie, Gerard J Graham, Anand Manoharan, Christina Halsey, Karen Blyth, Monika C Wolkers, Crispin Miller, Daniel J Pennington, Gareth W Jones, Jean-Jacques Fournie, Vasileios Bekiaris, Seth B Coffelt
IL-27 maintains cytotoxic Ly6C + γδ T cells that arise from immature precursors. The EMBO journal (2024)
Robert Wiesheu, Sarah C Edwards, Ann Hedley, Holly Hall, Marie Tosolini, Marcelo Gregorio Filho Fares da Silva, Nital Sumaria, Suzanne M Castenmiller, Leyma Wardak, Yasmin Optaczy, Amy Lynn, David G Hill, Alan J Hayes, Jodie Hay, Anna Kilbey, Robin Shaw, Declan Whyte, Peter J Walsh, Alison M Michie, Gerard J Graham, Anand Manoharan, Christina Halsey, Karen Blyth, Monika C Wolkers, Crispin Miller, Daniel J Pennington, Gareth W Jones, Jean-Jacques Fournie, Vasileios Bekiaris, Seth B Coffelt
IL-27 maintains cytotoxic Ly6C + γδ T cells that arise from immature precursors. The EMBO journal 43 (14) (2024)
Alice Santi, Emily J Kay, Lisa J Neilson, Lynn McGarry, Sergio Lilla, Margaret Mullin, Nikki R Paul, Frédéric Fercoq, Grigorios Koulouras, Giovanny Rodriguez Blanco, Dimitris Athineos, Susan Mason, Mark Hughes, Gemma Thomson, Yann Kieffer, Colin Nixon, Karen Blyth, Fatima Mechta-Grigoriou, Leo M Carlin, Sara R Zanivan
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science signaling 17 (827) (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer 5 (4) (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer 5 (4) (2024)
Piotr Dzien, Ximena Raffo Iraolagoitia, Stephanie May, David Stevenson, Lynn McGarry, Dmitry Soloviev, Gavin Brown, Colin Nixon, Chrysa Kapeni, Maike De La Roche, Karen Blyth, Scott Lyons, Thomas Bird, Douglas Strathdee, Gilbert O Fruhwirth, Leo Carlin, David Y Lewis
Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system. Research square (2024)
Alice Santi, Emily J Kay, Lisa J Neilson, Lynn McGarry, Sergio Lilla, Margaret Mullin, Nikki R Paul, Frédéric Fercoq, Grigorios Koulouras, Giovanny Rodriguez Blanco, Dimitris Athineos, Susan Mason, Mark Hughes, Gemma Thomson, Yann Kieffer, Colin Nixon, Karen Blyth, Fatima Mechta-Grigoriou, Leo M Carlin, Sara R Zanivan
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science signaling 17 (827) (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer (2024)
Florian J Bock, Egor Sedov, Elle Koren, Anna L Koessinger, Catherine Cloix, Désirée Zerbst, Dimitris Athineos, Jayanthi Anand, Kirsteen J Campbell, Karen Blyth, Yaron Fuchs, Stephen W G Tait
Author Correction: Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature communications 15 (1) (2024)
Dritan Liko, Louise Mitchell, Kirsteen J Campbell, Rachel A Ridgway, Carolyn Jones, Kate Dudek, Ayala King, Sheila Bryson, David Stevenson, Karen Blyth, Douglas Strathdee, Jennifer P Morton, Thomas G Bird, John R P Knight, Anne E Willis, Owen James Sansom
Correction to: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas. Cell death and differentiation (2024)
Robert Wiesheu, Sarah C Edwards, Ann Hedley, Holly Hall, Marie Tosolini, Marcelo Gregorio Filho Fares da Silva, Nital Sumaria, Suzanne M Castenmiller, Leyma Wardak, Yasmin Optaczy, Amy Lynn, David G Hill, Alan J Hayes, Jodie Hay, Anna Kilbey, Robin Shaw, Declan Whyte, Peter J Walsh, Alison M Michie, Gerard J Graham, Anand Manoharan, Christina Halsey, Karen Blyth, Monika C Wolkers, Crispin Miller, Daniel J Pennington, Gareth W Jones, Jean-Jacques Fournie, Vasileios Bekiaris, Seth B Coffelt
IL-27 maintains cytotoxic Ly6C + γδ T cells that arise from immature precursors. The EMBO journal 43 (14) (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer (2024)
Robert Wiesheu, Sarah C Edwards, Ann Hedley, Holly Hall, Marie Tosolini, Marcelo Gregorio Filho Fares da Silva, Nital Sumaria, Suzanne M Castenmiller, Leyma Wardak, Yasmin Optaczy, Amy Lynn, David G Hill, Alan J Hayes, Jodie Hay, Anna Kilbey, Robin Shaw, Declan Whyte, Peter J Walsh, Alison M Michie, Gerard J Graham, Anand Manoharan, Christina Halsey, Karen Blyth, Monika C Wolkers, Crispin Miller, Daniel J Pennington, Gareth W Jones, Jean-Jacques Fournie, Vasileios Bekiaris, Seth B Coffelt
IL-27 maintains cytotoxic Ly6C + γδ T cells that arise from immature precursors. The EMBO journal 43 (14) (2024)
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta-Uribe, Engy Shokry, Alex L Young, Sergio Lilla, Minsoo Kim, Tricia Park, Sonia Boscenco, Javier L Manchon, Crístina Rodríguez-Antona, Rowan C Walters, Roger J Springett, James N Blaza, Louise Mitchell, Karen Blyth, Sara Zanivan, David Sumpton, Edward W Roberts, Ed Reznik, Payam A Gammage
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature cancer (2024)
Piotr Dzien, Ximena Raffo Iraolagoitia, Stephanie May, David Stevenson, Lynn McGarry, Dmitry Soloviev, Gavin Brown, Colin Nixon, Chrysa Kapeni, Maike De La Roche, Karen Blyth, Scott Lyons, Thomas Bird, Douglas Strathdee, Gilbert O Fruhwirth, Leo Carlin, David Y Lewis
Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system. Research square (2024)
Adiba S Khan, Kirsteen J Campbell, Ewan R Cameron, Karen Blyth
The RUNX/CFBβ Complex in Breast Cancer: A Conundrum of Context. Cells 12 (4) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Adiba S Khan, Kirsteen J Campbell, Ewan R Cameron, Karen Blyth
The RUNX/CFBβ Complex in Breast Cancer: A Conundrum of Context. Cells 12 (4) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Vasileios Papalazarou, Alice C Newman, Alejandro Huerta-Uribe, Nathalie M Legrave, Mattia Falcone, Tong Zhang, Lynn McGarry, Dimitris Athineos, Emma Shanks, Karen Blyth, Karen H Vousden, Oliver D K Maddocks
Phenotypic profiling of solute carriers characterizes serine transport in cancer. Nature metabolism (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Peter Bailey, Rachel A Ridgway, Patrizia Cammareri, Mairi Treanor-Taylor, Ulla-Maja Bailey, Christina Schoenherr, Max Bone, Daniel Schreyer, Karin Purdie, Jason Thomson, William Rickaby, Rene Jackstadt, Andrew D Campbell, Emmanouil Dimonitsas, Alexander J Stratigos, Sarah T Arron, Jun Wang, Karen Blyth, Charlotte M Proby, Catherine A Harwood, Owen James Sansom, Irene M Leigh, Gareth J Inman
Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression. Nature communications 14 (1) (2023)
Adiba S Khan, Kirsteen J Campbell, Ewan R Cameron, Karen Blyth
The RUNX/CFBβ Complex in Breast Cancer: A Conundrum of Context. Cells 12 (4) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Toshiyasu Suzuki, Anna Kilbey, Nuria Casa-Rodríguez, Amy Lawlor, Anastasia Georgakopoulou, Hannah Hayman, Kyi Lai Yin Swe, Anna Nordin, Claudio Cantú, Pierre Vantourout, Rachel A Ridgway, Ryan M Byrne, Lei Chen, Michael P Verzi, David M Gay, Ester Gil Vazquez, Hayley L Belnoue-Davis, Kathryn L Gilroy, Anne Helene Kostner, Christian Kersten, Chanitra Thuwajit, Ditte K Andersen, Robert Wiesheu, Anett Jandke, Karen Blyth, Antonia K Roseweir, Simon J Leedham, Philip David Dunne, Joanne Edwards, Adrian C Hayday, Owen James Sansom, Seth B Coffelt
β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer. Cancer immunology research (2023)
Adiba S Khan, Kirsteen J Campbell, Ewan R Cameron, Karen Blyth
The RUNX/CFBβ Complex in Breast Cancer: A Conundrum of Context. Cells 12 (4) (2023)
Adiba S Khan, Kirsteen J Campbell, Ewan R Cameron, Karen Blyth
The RUNX/CBFβ Complex in Breast Cancer: A Conundrum of Context. Cells 12 (4) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Pavlina Spiliopoulou, Sarah Spear, Hasan B Mirza, Ian Garner, Lynn McGarry, Fabio Grundland-Freile, Zhao Cheng, Darren P Ennis, Nayana Iyer, Sophie McNamara, Marina Natoli, Susan Mason, Karen Blyth, Peter D Adams, Patricia Roxburgh, Matthew John Fuchter, Robert Brown, Iain A McNeish
Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma. Molecular cancer therapeutics 21 (4) (2022)
Anna L Koessinger, Catherine Cloix, Dominik Koessinger, Dieter Henrik Heiland, Florian J Bock, Karen Strathdee, Kevin Kinch, Laura Martínez-Escardó, Nikki R Paul, Colin Nixon, Gaurav Malviya, Mark R Jackson, Kirsteen J Campbell, Katrina Stevenson, Sandeep Davis, Yassmin Elmasry, Asma Ahmed, Jim O'Prey, Gabriel Ichim, Oliver Schnell, William Stewart, Karen Blyth, Kevin M Ryan, Anthony J Chalmers, James C Norman, Stephen W G Tait
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell death and differentiation 29 (10) (2022)
Timothy J Humpton, Andreas K Hock, Christos Kiourtis, Marco De Donatis, Frédéric Fercoq, Colin Nixon, Sheila Bryson, Douglas Strathdee, Leo M Carlin, Thomas G Bird, Karen Blyth, Karen H Vousden
A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo. Science signaling 15 (720) (2022)
Victor H Villar, Maria Francesca Allega, Ruhi S Deshmukh, Tobias Ackermann, Mark A Nakasone, Johan Vande Voorde, Thomas M Drake, Janina Oetjen, Algernon Bloom, Colin Nixon, Miryam Müller, Stephanie May, Ee Hong Tan, Lars Vereecke, Maude Jans, Gillian Blancke, Daniel J Murphy, Danny T Huang, David Y Lewis, Thomas G Bird, Owen James Sansom, Karen Blyth, David Sumpton, Saverio Tardito
Hepatic glutamine synthetase controls N 5 -methylglutamine in homeostasis and cancer. Nature chemical biology (2022)
Sarah C Edwards, Ann Hedley, Wilma H M Hoevenaar, Robert Wiesheu, Teresa Glauner, Anna Kilbey, Robin Shaw, Katerina Boufea, Nizar N Batada, Shinya Hatano, Yasunobu Yoshikai, Karen Blyth, Crispin J Miller, Kristina Kirschner, Seth B Coffelt
PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing γδ T cells. The Journal of experimental medicine 220 (2) (2022)
Mattia Falcone, Alejandro Huerta Uribe, Vasileios Papalazarou, Alice C Newman, Dimitris Athineos, Katrina Stevenson, Charles-Etienne Gabriel Sauvé, Yajing Gao, Jin K Kim, Michael Del Latto, Maria Kierstead, Chao Wu, J Joshua Smith, Paul B Romesser, Anthony J Chalmers, Karen Blyth, Oliver D K Maddocks
Sensitisation of cancer cells to radiotherapy by serine and glycine starvation. British journal of cancer 127 (10) (2022)
Anne-Louise Latif, Ashley Newcombe, Sha Li, Kathryn Gilroy, Neil Alistair Robertson, Xue Lei, Helen J S Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-Ichi Sakamaki, Jennifer P Morton, Kevin M Ryan, Stephen W G Tait, Sheela A Abraham, Tessa Holyoake, Brian Higgins, Xu Huang, Karen Blyth, Mhairi Copland, Timothy J T Chevassut, Karen Keeshan, Peter D Adams
BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature communications 12 (1) (2021)
Florian J Bock, Egor Sedov, Elle Koren, Anna L Koessinger, Catherine Cloix, Désirée Zerbst, Dimitris Athineos, Jayanthi Anand, Kirsteen J Campbell, Karen Blyth, Yaron Fuchs, Stephen W G Tait
Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature communications 12 (1) (2021)
Kirsteen J Campbell, Susan M Mason, Matthew L Winder, Rosalie B E Willemsen, Catherine Cloix, Hannah Lawson, Nicholas Rooney, Sandeep Dhayade, Andrew H Sims, Karen Blyth, Stephen W G Tait
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell death and differentiation 28 (9) (2021)
Mylène Tajan, Marc Hennequart, Eric C Cheung, Fabio Zani, Andreas K Hock, Nathalie Legrave, Oliver D K Maddocks, Rachel A Ridgway, Dimitris Athineos, Alejandro Suarez-Bonnet, Robert L Ludwig, Laura Novellasdemunt, Nikolaos Angelis, Vivian Sze Wing Li, Georgios Vlachogiannis, Nicola Valeri, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, Karen Blyth, Owen James Sansom, Karen H Vousden
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy. Nature communications 12 (1) (2021)
Marisa Nacke, Emma Sandilands, Konstantina Nikolatou, Álvaro Román-Fernández, Susan Mason, Rachana Patel, Sergio Lilla, Tamas Yelland, Laura C A Galbraith, Eva C Freckmann, Lynn McGarry, Jennifer P Morton, Emma Shanks, Hing Y Leung, Elke Markert, Shehab Ismail, Sara R Zanivan, Karen Blyth, David M Bryant Editor
An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism. Nature communications 12 (1) (2021)
Nicholas Rooney, Susan M Mason, Laura McDonald, J Henry M Däbritz, Kirsteen J Campbell, Ann Hedley, Steven Howard, Dimitris Athineos, Colin Nixon, William Clark, Joshua D G Leach, Owen J Sansom, Joanne Edwards, Ewan R Cameron, Karen Blyth
RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome. Cancer research 80 (11) (2020)
Rhona Millar, Anna Kilbey, Sarah-Jane Remak, Tesa M Severson, Sandeep Dhayade, Emma Sandilands, Kyla Foster, David M Bryant Editor, Karen Blyth, Seth B Coffelt
The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer. Molecular oncology 14 (8) (2020)
Kirsteen J Campbell, Karen Blyth
Somatic base editing to model oncogenic drivers in breast cancer. Lab animal 49 (4) (2020)
Sandeep Dhayade, Matthias Pietzke, Robert Wiesheu, Jacqueline Tait-Mulder, Dimitris Athineos, David Sumpton, Seth B Coffelt, Karen Blyth, Alexei Vazquez
Impact of Formate Supplementation on Body Weight and Plasma Amino Acids. Nutrients 12 (8) (2020)
Tong Zhang, Christin Bauer, Alice C Newman, Alejandro Huerta Uribe, Dimitris Athineos, Karen Blyth, Oliver D K Maddocks
Polyamine pathway activity promotes cysteine essentiality in cancer cells. Nature metabolism 2 (10) (2020)
Carolyn J Loveridge, Sarah Slater, Kirsteen J Campbell, Noor A Nam, John Knight, Owen J Sansom, Ann Hedley, Sergio Lilla, Peter Repiscak, Rachana Patel, Mark Salji, Janis Fleming, Louise Mitchell, Colin Nixon, Douglas Strathdee, Matthew Neilson, Chara Ntala, Sheila Bryson, Sara R Zanivan, Joanne Edwards, Craig N Robson, Carl S Goodyear, Karen Blyth, Hing Y Leung
BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene 39 (8) (2019)
Dritan Liko, Louise Mitchell, Kirsteen J Campbell, Rachel A Ridgway, Carolyn Jones, Kate Dudek, Ayala King, Sheila Bryson, David Stevenson, Karen Blyth, Douglas Strathdee, Jennifer P Morton, Thomas G Bird, John R P Knight, Anne E Willis, Owen James Sansom
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas. Cell death and differentiation 26 (12) (2019)
David Novo, Nikki Heath, Louise Mitchell, Giuseppina Caligiuri, Amanda MacFarlane, Dide Reijmer, Laura Charlton, John Knight, Monika Calka, Ewan McGhee, Emmanuel Dornier, David Sumpton, Susan Mason, Arnaud Echard, Kerstin Klinkert, Judith Secklehner, Flore Kruiswijk, Karen Vousden, Iain R J Macpherson, Karen Blyth, Peter Bailey, Huabing Yin, Leo M Carlin, Jennifer Morton, Sara R Zanivan, Jim C Norman
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nature communications 9 (1) (2018)
Kirsteen J Campbell, Sandeep Dhayade, Nicola Ferrari, Andrew H Sims, Emma Johnson, Susan M Mason, Ashley Dickson, Kevin M Ryan, Gabriela Kalna, Joanne Edwards, Stephen W G Tait, Karen Blyth
MCL-1 is a prognostic indicator and drug target in breast cancer. Cell death & disease 9 (2) (2018)
Johannes Meiser, Anne Schuster, Matthias Pietzke, Johan Vande Voorde, Dimitris Athineos, Kristell Oizel, Guillermo Burgos-Barragan, Niek Wit, Sandeep Dhayade, Jennifer P Morton, Emmanuel Dornier, David Sumpton, Gillian M Mackay, Karen Blyth, Ketan J Patel, Simone P Niclou, Alexei Vazquez
Increased formate overflow is a hallmark of oxidative cancer. Nature communications 9 (1) (2018)
Ingunn Holen, Valerie Speirs, Bethny Morrissey, Karen Blyth
In vivo models in breast cancer research: progress, challenges and future directions. Disease models & mechanisms 10 (4) (2017)
Melanie Weigert, Alex Binks, Suzanne Dowson, Elaine Y L Leung, Dimitris Athineos, Xinzi Yu, Margaret Mullin, Josephine B Walton, Clare Orange, Darren Ennis, Karen Blyth, Stephen W G Tait, Iain A McNeish
RIPK3 promotes adenovirus type 5 activity. Cell death & disease 8 (12) (2017)
Evangelos Giampazolias, Barbara Zunino, Sandeep Dhayade, Florian Bock, Catherine Cloix, Kai Cao, Alba Roca, Jonathan Lopez, Gabriel Ichim, Emma Proïcs, Camila Rubio-Patiño, Loic Fort, Nader Yatim, Emma Woodham, Susana Orozco, Lucia Taraborrelli, Nieves Peltzer, Daniele Lecis, Laura Machesky, Henning Walczak, Matthew L Albert, Simon Milling, Andrew Oberst, Jean-Ehrland Ricci, Kevin M Ryan, Karen Blyth, Stephen W G Tait
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nature cell biology 19 (9) (2017)
Emmanuel Dornier, Nicolas Rabas, Louise Mitchell, David Novo, Sandeep Dhayade, Sergi Marco, Gillian Mackay, David Sumpton, Maria Pallares, Colin Nixon, Karen Blyth, Iain R J Macpherson, Elena Rainero, Jim C Norman
Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells. Nature communications 8 (1) (2017)

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Karen Blyth