Andrew H Sims

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 30

Top Venues

Oncogene

Cancers

Nature communications

Breast cancer research : BCR

University of Edinburgh

University of Manchester (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Edinburgh Jun 01 2008

United Kingdom

Senior Research Fellow :: Edinburgh Cancer Research Centre

Education History

University of Manchester

United Kingdom

PHD :: Life Sciences

Publications

Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene 42 (9) (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene 42 (9) (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene 42 (9) (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene 42 (9) (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene 42 (9) (2023)
Fuhui Chen, Sevim B Gurler, David Novo, Cigdem Selli, Denis G Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H Sims, Neil E Humphreys, Antony Adamson, Andrew D Campbell, Owen James Sansom, Cathy Tournier, Robert B Clarke, Keith Brennan, Charles H Streuli, Ahmet Ucar
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells. Oncogene 42 (9) (2023)
Joy Edwards-Hicks, Huizhong Su, Maurizio Mangolini, Kubra K Yoneten, Jimi C Wills, Giovanny Rodriguez-Blanco, Christine Young, Kevin Cho, Heather Barker, Morwenna Muir, Ania Naila Guerrieri, Xue-Feng Li, Rachel White, Piotr Manasterski, Elena Mandrou, Karen Wills, Jingyu Chen, Emily Abraham, Kianoosh Sateri, Bin-Zhi Qian, Peter Bankhead, Mark J Arends, Noor Gammoh, Alexander von Kriegsheim, Gary J Patti, Andrew H Sims, Juan Carlos Acosta, Valerie Brunton, Kamil R Kranc, Maria A Christophorou, Erika L Pearce, Ingo Ringshausen, Andrew J Finch
MYC sensitises cells to apoptosis by driving energetic demand. Nature communications 13 (1) (2022)
Laura Gómez-Cuadrado, Esme Bullock, Zeanap Mabruk, Hong Zhao, Margarita Souleimanova, Pernille Rimmer Noer, Arran K Turnbull, Claus Oxvig, Nicholas Bertos, Adam Byron, J Michael Dixon, Morag Park, Syed Haider, Rachael Natrajan, Andrew H Sims, Valerie G Brunton
Characterisation of the Stromal Microenvironment in Lobular Breast Cancer. Cancers 14 (4) (2022)
Henry Beetham, Billie G C Griffith, Olga Murina, Alexander E P Loftus, David A Parry, Carolin Temps, Jayne Culley, Morwenna T Muir, Asier Unciti-Broceta, Andrew H Sims, Adam Byron, Valerie G Brunton
Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors. Cancer research 82 (4) (2022)
Rebecca Williams, Stephanie Jobling, Andrew H Sims, Chunyan Mou, Lorna Wilkinson, Giovanna M Collu, Charles H Streuli, Andrew P Gilmore, Denis J Headon, Keith Brennan
Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia. Oncogene 41 (7) (2021)
Kirsteen J Campbell, Susan M Mason, Matthew L Winder, Rosalie B E Willemsen, Catherine Cloix, Hannah Lawson, Nicholas Rooney, Sandeep Dhayade, Andrew H Sims, Karen Blyth, Stephen W G Tait
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell death and differentiation 28 (9) (2021)
Rachel Bleach, Stephen F Madden, James Hawley, Sara Charmsaz, Cigdem Selli, Katherine M Sheehan, Leonie S Young, Andrew H Sims, Pavel Souček, Arnold D Hill, Marie McIlroy
Steroid Ligands, the Forgotten Triggers of Nuclear Receptor Action; Implications for Acquired Resistance to Endocrine Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (14) (2021)
Damir Varešlija, Elspeth Ward, Siobhan P Purcell, Nicola S Cosgrove, Sinéad Cocchiglia, Philip J O'Halloran, Sara Charmsaz, Fiona T Bane, Francesca M Brett, Michael Farrell, Jane Cryan, Alan Beausang, Lance Hudson, Arran K Turnbul, J Michael Dixon, Arnold D K Hill, Nolan Priedigkeit, Steffi Oesterreich, Adrian V Lee, Andrew H Sims, Aisling M Redmond, Jason S Carroll, Leonie S Young
Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype. Oncogene 40 (7) (2021)
Maria Grazia Muoio, Marianna Talia, Rosamaria Lappano, Andrew H Sims, Veronica Vella, Francesca Cirillo, Livia Manzella, Marika Giuliano, Marcello Maggiolini, Ernestina Marianna De Francesco, Ernestina Marianna De Francesco
Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer. Cancers 13 (4) (2021)
Veronica Vella, Marika Giuliano, Alessandro La Ferlita, Michele Pellegrino, Germano Gaudenzi, Salvatore Alaimo, Michele Massimino, Alfredo Pulvirenti, Alessandra Dicitore, Paolo Vigneri, Giovanna Mantovani, Roberta Malaguarnera, Andrea Morrione, Andrew H Sims, Alfredo Ferro, Marcello Maggiolini, Rosamaria Lappano, Ernestina Marianna De Francesco, Ernestina Marianna De Francesco
Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells. Cells 10 (11) (2021)
Marta Canel, David Taggart, Andrew H Sims, David W Lonergan, Irene C Waizenegger, Alan Serrels
T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. eLife 9 (2020)
Arran K Turnbull, Cigdem Selli, Carlos Martinez-Perez, Anu Fernando, Lorna Renshaw, Jane Keys, Jonine D Figueroa, Xiaping He, Maki Tanioka, Alison F Munro, Lee Murphy, Angie Fawkes, Richard Clark, Audrey Coutts, Charles M Perou, Lisa A Carey, J Michael Dixon, Andrew H Sims
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: comparison of gene expression profiling approaches. BMC bioinformatics 21 (1) (2020)
Marianna Talia, Ernestina Marianna De Francesco, Damiano Cosimo Rigiracciolo, Maria Grazia Muoio, Lucia Muglia, Antonino Belfiore, Marcello Maggiolini, Andrew H Sims, Rosamaria Lappano
The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis. Cells 9 (3) (2020)
Ian M Overton, Andrew H Sims, Jeremy A Owen, Bret S E Heale, Matthew J Ford, Alexander L R Lubbock, Erola Pairo-Castineira, Abdelkader Essafi
Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling. Cancers 12 (10) (2020)
Yanping Xie, Brittny C Davis Lynn, Nicholas Moir, David A Cameron, Jonine D Figueroa, Andrew H Sims
Breast cancer gene expression datasets do not reflect the disease at the population level. NPJ breast cancer 6 (2020)
Akanksha Mishra, Maria Bonello, Adam Byron, Simon P Langdon, Andrew H Sims
Evaluation of Gene Expression Data From Cybrids and Tumours Highlights Elevated NDRG1-Driven Proliferation in Triple-Negative Breast Cancer. Breast cancer : basic and clinical research 14 (2020)
Bruno M Simões, Angélica Santiago-Gómez, Chiara Chiodo, Tiago Moreira, Daniel Conole, Scott Lovell, Denis Alferez, Rachel Eyre, Katherine Spence, Aida Sarmiento-Castro, Bertram Kohler, Ludivine Morisset, Marilena Lanzino, Sebastiano Andò, Elisabetta Marangoni, Andrew H Sims, Edward William Tate, Sacha J Howell, Robert B Clarke
Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer. Oncogene 39 (25) (2020)
Andrew H Sims, Melanie Leggate, Anna Campbell
Exercise Window Trial in Newly Diagnosed Breast Cancer-Letter. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (24) (2020)
Rachel Eyre, Denis G Alférez, Angélica Santiago-Gómez, Kath Spence, James C McConnell, Claire Hart, Bruno M Simões, Diane Lefley, Claudia Tulotta, Joanna Storer, Austin Gurney, Noel Clarke, Michael D Brown, Sacha J Howell, Andrew H Sims, Gillian Farnie, Penelope D Ottewell, Robert B Clarke
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nature communications 10 (1) (2019)
Márcia A Inda, Erik J Blok, Peter J K Kuppen, Ayoub Charehbili, Eveline C den Biezen-Timmermans, Anne van Brussel, Sevgi E Fruytier, Elma Meershoek-Klein Kranenbarg, Susan L Kloet, Bart van der Burg, John W M Martens, Andrew H Sims, Arran K Turnbull, J Michael Dixon, Wim F J Verhaegh, Judith R Kroep, Cornelis J H van de Velde, Anja van de Stolpe
Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer. Molecular cancer therapeutics 19 (2) (2019)
Richard J Bownes, Arran K Turnbull, Carlos Martinez-Perez, David A Cameron, Andrew H Sims, Olga Oikonomidou
On-treatment biomarkers can improve prediction of response to neoadjuvant chemotherapy in breast cancer. Breast cancer research : BCR 21 (1) (2019)
Cigdem Selli, Arran K Turnbull, Dominic A Pearce, Ang Li, Anu Fernando, Jimi Wills, Lorna Renshaw, Jeremy S Thomas, J Michael Dixon, Andrew H Sims
Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours. Breast cancer research : BCR 21 (1) (2019)
Ajit J Nirmal, Tim Regan, Barbara B Shih, David A Hume, Andrew H Sims, Tom C Freeman
Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors. Cancer immunology research 6 (11) (2018)

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Publication Activity (10 Years)

Top Topics

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Andrew H Sims