Thomas Spangenberg

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 29

Top Topics

Toxoplasma Gondii

Top Venues

ACS infectious diseases

Nature communications

ACS medicinal chemistry letters

PLoS neglected tropical diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Diego González Cabrera, Jennifer Keiser, Thomas Spangenberg
Analysis of the Physicochemical Properties of Anti-Schistosomal Compounds to Identify Next-Generation Leads. ACS medicinal chemistry letters 15 (5) (2024)
Diego González Cabrera, Jennifer Keiser, Thomas Spangenberg
Analysis of the Physicochemical Properties of Anti-Schistosomal Compounds to Identify Next-Generation Leads. ACS medicinal chemistry letters 15 (5) (2024)
Mohamed Maiga, Laurent Dembele, Perrine Courlet, Akash Khandelwal, Antoine Dara, Fanta Sogore, Ousmaila Diakité, Fatoumata O Maiga, Francois Dao, Sekou Sissoko, Yacouba Barre, Siaka Goita, Mahamadou Diakité, Seidina A S Diakite, Abdoulaye A Djimde, Claude Oeuvray, Thomas Spangenberg, Sebastian Georg Wicha, Claudia Demarta-Gatsi
Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data. Nature communications 15 (1) (2024)
Mohamed Maiga, Laurent Dembele, Perrine Courlet, Akash Khandelwal, Antoine Dara, Fanta Sogore, Ousmaila Diakité, Fatoumata O Maiga, Francois Dao, Sekou Sissoko, Yacouba Barre, Siaka Goita, Mahamadou Diakité, Seidina A S Diakite, Abdoulaye A Djimde, Claude Oeuvray, Thomas Spangenberg, Sebastian Georg Wicha, Claudia Demarta-Gatsi
Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data. Nature communications 15 (1) (2024)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Eva Stadler, Mohamed Maiga, Lukas Friedrich, Vandana Thathy, Claudia Demarta-Gatsi, Antoine Dara, Fanta Sogore, Josefine Striepen, Claude Oeuvray, Abdoulaye A Djimde, Marcus Chee San Lee, Laurent Dembélé, David A Fidock, David S Khoury, Thomas Spangenberg
Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine. Nature communications 14 (1) (2023)
Eva Stadler, Mohamed Maiga, Lukas Friedrich, Vandana Thathy, Claudia Demarta-Gatsi, Antoine Dara, Fanta Sogore, Josefine Striepen, Claude Oeuvray, Abdoulaye A Djimde, Marcus Chee San Lee, Laurent Dembélé, David A Fidock, David S Khoury, Thomas Spangenberg
Propensity of selecting mutant parasites for the antimalarial drug cabamiquine. Nature communications 14 (1) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases 9 (5) (2023)
Diego González Cabrera, Dennis A Smith, Gregory S Basarab, James Duffy, Thomas Spangenberg, Kelly Chibale
Anti-infectives Developed as Racemic Drugs in the 21st Century: Norm or Exception? ACS medicinal chemistry letters 14 (7) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Daniel J Sprague, Marc Kaethner, Sang-Kyu Park, Claudia M Rohr, Jade L Harris, David Maillard, Thomas Spangenberg, Britta Lundström-Stadelmann, Jonathan S Marchant
The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM PZQ Orthologs. ACS medicinal chemistry letters 14 (11) (2023)
Nicola Caldwell, Rana Afshar, Beatriz Baragaña, Amaya L Bustinduy, Conor R Caffrey, James J Collins, Daniela Fusco, Amadou Garba, Mark Gardner, Mireille Gomes, Karl F Hoffmann, Michael Hsieh, Nathan C Lo, Case W MacNamara, Justin Komguep Nono, Gilda Padalino, Kevin D Read, Meta Roestenberg, Thomas Spangenberg, Sabine Specht, Ian H Gilbert
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. ACS infectious diseases (2023)
Akash Khandelwal, Francisca Arez, Paula M Alves, Lassina Badolo, Catarina Brito, Christoph Fischli, Diana Fontinha, Claude Oeuvray, Miguel Prudêncio, Matthias Rottmann, Justin Wilkins, Özkan Yalkinoglu, Wilhelmina M Bagchus, Thomas Spangenberg
Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside. Malaria journal 21 (1) (2022)
Diana Fontinha, Francisca Arez, Isabella Ramella Gal, Gonçalo Nogueira, Diana Moita, Tobias Hyun Ho Baeurle, Catarina Brito, Thomas Spangenberg, Paula M Alves, Miguel Prudncio
Pre-erythrocytic Activity of M5717 in Monotherapy and Combination in Preclinical Plasmodium Infection Models. ACS infectious diseases 8 (4) (2022)
Youssef Hamway, Kaspar Zimmermann, Marcel J J Blommers, Mariana V Sousa, Cécile Häberli, Shashank Kulkarni, Susanna Skalicky, Matthias Hackl, Marjo Götte, Jennifer Keiser, Clarissa Prazeres da Costa, Thomas Spangenberg, Kamal Azzaoui
Modulation of Host-Parasite Interactions with Small Molecules Targeting Schistosoma mansoni microRNAs. ACS infectious diseases 8 (10) (2022)
Sang-Kyu Park, Lukas Friedrich, Nawal A Yahya, Claudia M Rohr, Evgeny G Chulkov, David Maillard, Friedrich Rippmann, Thomas Spangenberg, Jonathan S Marchant
Mechanism of praziquantel action at a parasitic flatworm ion channel. Science translational medicine 13 (625) (2021)
Nermina Vejzagić, Ulrich Fabien Prodjinotho, Nagwa El-Khafif, Ruili Huang, Anton Simeonov, Thomas Spangenberg, Clarissa Prazeres da Costa
Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium. PLoS neglected tropical diseases 15 (5) (2021)
Matthias Rottmann, Brian Jonat, Christin Gumpp, Satish K Dhingra, Marla J Giddins, Xiaoyan Yin, Lassina Badolo, Beatrice Greco, David A Fidock, Claude Oeuvray, Thomas Spangenberg
Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor. Antimicrobial agents and chemotherapy 64 (4) (2020)
Thomas Spangenberg
Alternatives to Praziquantel for the Prevention and Control of Schistosomiasis. ACS infectious diseases 7 (5) (2020)
Shashank Kulkarni, Klaus Urbahns, Thomas Spangenberg
Targeted Covalent Inhibitors for the Treatment of Malaria? ACS infectious diseases 6 (11) (2020)
Manu De Rycker, David Horn, Bree Aldridge, Richard K Amewu, Clifton E Barry, Frederick S Buckner, Sarah Cook, Michael A J Ferguson, Nathalie Gobeau, Jennifer Herrmann, Paul Herrling, William Hope, Jennifer Keiser, Maria Jose Lafuente-Monasterio, Paul D Leeson, Didier Leroy, Ujjini H Manjunatha, James McCarthy, Timothy J Miles, Valerie Mizrahi, Olena Moshynets, Jacquin Niles, John P Overington, John Pottage, Srinivasa P S Rao, Kevin D Read, Isabela Ribeiro, Lynn L Silver, Jen Southern, Thomas Spangenberg, Shyam Sundar, Caitlin Taylor, Wes Van Voorhis, Nicholas J White, Susan Wyllie, Paul G Wyatt, Ian H Gilbert
Setting Our Sights on Infectious Diseases. ACS infectious diseases 6 (1) (2019)
Francisca Arez, Sofia P Rebelo, Diana Fontinha, Daniel Simão, Tatiana R Martins, Marta Machado, Christoph Fischli, Claude Oeuvray, Lassina Badolo, Manuel J T Carrondo, Matthias Rottmann, Thomas Spangenberg, Catarina Brito, Beatrice Greco, Miguel Prudêncio, Paula M Alves
Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection. ACS infectious diseases 5 (11) (2019)
Nishanth Kandepedu, Diego Gonzàlez Cabrera, Srinivas Eedubilli, Dale Taylor, Christel Brunschwig, Liezl Gibhard, Mathew Njoroge, Nina Lawrence, Tanya Paquet, Charles J Eyermann, Thomas Spangenberg, Gregory S Basarab, Leslie J Street, Kelly Chibale
Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria. Journal of medicinal chemistry 61 (13) (2018)
Nada Abla, Jennifer Keiser, Mireille Vargas, Natalie Reimers, Helmut Haas, Thomas Spangenberg
Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model. PLoS neglected tropical diseases 11 (9) (2017)