Teppei Kawahara (Kazuo Shin-Ya)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 47

Top Topics

Structural Basis

Gas Chromatography Mass Spectrometry

Top Venues

The Journal of antibiotics

Angewandte Chemie (International ed. in English)

Chembiochem : a European journal of chemical biology

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Teppei Kawahara
Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds. The Journal of antibiotics 77 (5) (2024)
Takuya Hashimoto, Hikaru Suenaga, Keita Amagai, Junko Hashimoto, Ikuko Kozone, Shunji Takahashi, Teppei Kawahara
In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G q -Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont. Angewandte Chemie (International ed. in English) (2024)
Shunki Sakata, Jiafeng Li, Yoko Yasuno, Tetsuro Shinada, Teppei Kawahara, Yohei Katsuyama, Yasuo Ohnishi
Identification of the Cirratiomycin Biosynthesis Gene Cluster in Streptomyces Cirratus: Elucidation of the Biosynthetic Pathways for 2,3-Diaminobutyric Acid and Hydroxymethylserine. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (28) (2024)
Xiaoyu Song, Yuma Nihashi, Yukiko Imai, Nobuhito Mori, Noritaka Kagaya, Hikaru Suenaga, Teppei Kawahara, Masamichi Yamamoto, Daiki Setoyama, Yuya Kunisaki, Yasuyuki S Kida
Collagen Lattice Model, Populated with Heterogeneous Cancer-Associated Fibroblasts, Facilitates Advanced Reconstruction of Pancreatic Cancer Microenvironment. International journal of molecular sciences 25 (7) (2024)
Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Teppei Kawahara
Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds. The Journal of antibiotics (2024)
Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Teppei Kawahara
Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds. The Journal of antibiotics (2024)
Takuya Hashimoto, Hikaru Suenaga, Keita Amagai, Junko Hashimoto, Ikuko Kozone, Shunji Takahashi, Teppei Kawahara
In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G q -Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont. Angewandte Chemie (International ed. in English) 63 (10) (2024)
Xiaoyu Song, Yuma Nihashi, Yukiko Imai, Nobuhito Mori, Noritaka Kagaya, Hikaru Suenaga, Teppei Kawahara, Masamichi Yamamoto, Daiki Setoyama, Yuya Kunisaki, Yasuyuki S Kida
Collagen Lattice Model, Populated with Heterogeneous Cancer-Associated Fibroblasts, Facilitates Advanced Reconstruction of Pancreatic Cancer Microenvironment. International journal of molecular sciences 25 (7) (2024)
Shunki Sakata, Jiafeng Li, Yoko Yasuno, Tetsuro Shinada, Teppei Kawahara, Yohei Katsuyama, Yasuo Ohnishi
Identification of the Cirratiomycin Biosynthesis Gene Cluster in Streptomyces Cirratus: Elucidation of the Biosynthetic Pathways for 2,3-Diaminobutyric Acid and Hydroxymethylserine. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Takuya Hashimoto, Hikaru Suenaga, Keita Amagai, Junko Hashimoto, Ikuko Kozone, Shunji Takahashi, Teppei Kawahara
In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G q -Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont. Angewandte Chemie (International ed. in English) 63 (10) (2024)
Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Teppei Kawahara
Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds. The Journal of antibiotics 77 (5) (2024)
Takuya Hashimoto, Hikaru Suenaga, Keita Amagai, Junko Hashimoto, Ikuko Kozone, Shunji Takahashi, Teppei Kawahara
In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G q -Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont. Angewandte Chemie (International ed. in English) 63 (10) (2024)
Shiina Suzuki, Shun Saito, Yuki Narushima, Shunta Kodani, Noritaka Kagaya, Hikaru Suenaga, Teppei Kawahara, Midori A Arai
Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation. The Journal of antibiotics (2023)
Fumitaka Kudo, Kosuke Kishikawa, Kazuma Tsuboi, Takafusa Kido, Takeo Usui, Junko Hashimoto, Teppei Kawahara, Akimasa Miyanaga, Tadashi Eguchi
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics. Chembiochem : a European journal of chemical biology 24 (6) (2023)
Fumitaka Kudo, Kosuke Kishikawa, Kazuma Tsuboi, Takafusa Kido, Takeo Usui, Junko Hashimoto, Teppei Kawahara, Akimasa Miyanaga, Tadashi Eguchi
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics. Chembiochem : a European journal of chemical biology 24 (6) (2023)
Fumitaka Kudo, Kosuke Kishikawa, Kazuma Tsuboi, Takafusa Kido, Takeo Usui, Junko Hashimoto, Teppei Kawahara, Akimasa Miyanaga, Tadashi Eguchi
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics. Chembiochem : a European journal of chemical biology 24 (6) (2023)
Fumitaka Kudo, Kosuke Kishikawa, Kazuma Tsuboi, Takafusa Kido, Takeo Usui, Junko Hashimoto, Teppei Kawahara, Akimasa Miyanaga, Tadashi Eguchi
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics. Chembiochem : a European journal of chemical biology (2023)
Fumitaka Kudo, Kosuke Kishikawa, Kazuma Tsuboi, Takafusa Kido, Takeo Usui, Junko Hashimoto, Teppei Kawahara, Akimasa Miyanaga, Tadashi Eguchi
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics. Chembiochem : a European journal of chemical biology 24 (6) (2023)
Ayumu Demachi, Satoshi Ohte, Ryuji Uchida, Teppei Kawahara, Taichi Ohshiro, Hiroshi Tomoda, Haruo Ikeda
Discovery of prescopranone, a key intermediate in scopranone biosynthesis. The Journal of antibiotics 75 (6) (2022)
Fumitaka Kudo, Atsushi Minato, Shusuke Sato, Nayuta Nagano, Chitose Maruyama, Yoshimitsu Hamano, Junko Hashimoto, Ikuko Kozone, Teppei Kawahara, Tadashi Eguchi
Mechanism of S -Adenosyl-l-methionine C -Methylation by Cobalamin-dependent Radical S -Adenosyl-l-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis. Organic letters (2022)
Ryuhei Nagata, Hironori Suemune, Masaya Kobayashi, Tetsuro Shinada, Teppei Kawahara, Makoto Nishiyama, Tomoya Hino, Yusuke Sato, Tomohisa Kuzuyama, Shingo Nagano
Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-Like Enzymes. Angewandte Chemie (International ed. in English) 61 (20) (2022)
Seiji Kawai, Ryota Hagihara, Teppei Kawahara, Yohei Katsuyama, Yasuo Ohnishi
Bacterial Avenalumic Acid Biosynthesis Includes Substitution of an Aromatic Amino Group for Hydride by Nitrous Acid Dependent Diazotization. Angewandte Chemie (International ed. in English) 61 (45) (2022)
Kenichi Matsuda, Kuga Arima, Satoko Akiyama, Yuito Yamada, Yo Abe, Hikaru Suenaga, Junko Hashimoto, Teppei Kawahara, Makoto Nishiyama, Toshiyuki Wakimoto
A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme. Journal of the American Chemical Society 144 (28) (2022)
Yohei Katsuyama, Kaoru Sone, Ayaka Harada, Seiji Kawai, Naoki Urano, Naruhiko Adachi, Toshio Moriya, Masato Kawasaki, Teppei Kawahara, Toshiya Senda, Yasuo Ohnishi
Structural and Functional Analyses of the Tridomain-Nonribosomal Peptide Synthetase FmoA3 for 4-Methyloxazoline Ring Formation. Angewandte Chemie (International ed. in English) 60 (26) (2021)
Yasuko Yoneda, Kyosuke Yamamoto, Ayaka Makino, Yasuhiro Tanaka, Xian-Ying Meng, Junko Hashimoto, Teppei Kawahara, Noriyuki Satoh, Manabu Fujie, Tadashi Toyama, Kazuhiro Mori, Michihiko Ike, Masaaki Morikawa, Yoichi Kamagata, Hideyuki Tamaki
Novel Plant-Associated Acidobacteria Promotes Growth of Common Floating Aquatic Plants, Duckweeds. Microorganisms 9 (6) (2021)
Hikaru Suenaga, Noritaka Kagaya, Manabu Kawada, Daisuke Tatsuda, Toshiro Sato, Teppei Kawahara
Phenotypic screening system using three-dimensional (3D) culture models for natural product screening. The Journal of antibiotics 74 (10) (2021)
Hiroyuki Seimiya, Kazuo Nagasawa, Teppei Kawahara
Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics. The Journal of antibiotics 74 (10) (2021)
Takehiro Nishimura, Teppei Kawahara, Noritaka Kagaya, Yusuke Ogura, Hirosato Takikawa, Hikaru Suenaga, Masaatsu Adachi, Takatsugu Hirokawa, Takayuki Doi, Teppei Kawahara
JBIR-155, a Specific Class D β-Lactamase Inhibitor of Microbial Origin. Organic letters 23 (11) (2021)
Hayama Tsutsumi, Yoshitaka Moriwaki, Tohru Terada, Kentaro Shimizu, Teppei Kawahara, Yohei Katsuyama, Yasuo Ohnishi
Structural and Molecular Basis of the Catalytic Mechanism of Geranyl Pyrophosphate C6-Methyltransferase: Creation of an Unprecedented Farnesyl Pyrophosphate C6-Methyltransferase. Angewandte Chemie (International ed. in English) (2021)
Takuya Hashimoto, Junko Hashimoto, Noritaka Kagaya, Takehiro Nishimura, Hikaru Suenaga, Makoto Nishiyama, Tomohisa Kuzuyama, Teppei Kawahara
A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster. The Journal of antibiotics 74 (5) (2021)
Soniya Bastola, Marat S Pavlyukov, Daisuke Yamashita, Sadashib Ghosh, Heejin Cho, Noritaka Kagaya, Zhuo Zhang, Mutsuko Minata, Yeri Lee, Hirokazu Sadahiro, Shinobu Yamaguchi, Svetlana Komarova, Eddy Shih-Hsin Yang, James Markert, Louis Burt Nabors, Krishna Bhat, James Lee, Qin Chen, David K Crossman, Teppei Kawahara, Do-Hyun Nam, Ichiro Nakano
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy. Nature communications 11 (1) (2020)
Yoichi Hayakawa, Ryodai Yaguchi, Minami Akimoto, Shoko Kimata, Teppei Kawahara
Neocurromycin A, a new GRP78 downregulator from Streptomyces sp. RAI364. The Journal of antibiotics 73 (11) (2020)
Toshihiko Nogawa, Atsutaka Terai, Keita Amagai, Junko Hashimoto, Yushi Futamura, Akiko Okano, Manabu Fujie, Noriyuki Satoh, Haruo Ikeda, Teppei Kawahara, Hiroyuki Osada, Shunji Takahashi
Heterologous Expression of the Biosynthetic Gene Cluster for Verticilactam and Identification of Analogues. Journal of natural products 83 (12) (2020)
Yoichi Hayakawa, Tomohiro Yoshida, Shoko Kimata, Teppei Kawahara
Dunaimycin C3, a new GRP78 downregulator from Streptomyces sp. RAN389. The Journal of antibiotics 74 (1) (2020)
Chitose Maruyama, Yukiko Chinone, Shusuke Sato, Fumitaka Kudo, Kosuke Ohsawa, Junya Kubota, Junko Hashimoto, Ikuko Kozone, Takayuki Doi, Teppei Kawahara, Tadashi Eguchi, Yoshimitsu Hamano
C-Methylation of S-adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium. Biomolecules 10 (5) (2020)
Teppei Kawahara, Masashi Itoh, Miho Izumikawa, Noritaka Kagaya, Noriaki Sakata, Toshio Tsuchida, Kazuo Shin-Ya
New phenylspirodrimane metabolites MBJ-0030, MBJ-0031, and MBJ-0032 isolated from the soil fungal strain Stachybotrys sp. f23793. Bioscience, biotechnology, and biochemistry 84 (8) (2020)
Reiko Ueoka, Naoya Shinzato, Noritaka Kagaya, Hikaru Suenaga, Teppei Kawahara
Pseudoalteropeptide A, a novel lipopeptide from the marine bacterium Pseudoalteromonas piscicida SWA4_PA4 isolated from marine seaweed. The Journal of antibiotics 74 (2) (2020)
Tetsushi Kataura, Etsu Tashiro, Shota Nishikawa, Kensuke Shibahara, Yoshihito Muraoka, Masahiro Miura, Shun Sakai, Naohiro Katoh, Misato Totsuka, Masafumi Onodera, Teppei Kawahara, Kengo Miyamoto, Yukiko Sasazawa, Nobutaka Hattori, Shinji Saiki, Masaya Imoto
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers. Autophagy 17 (8) (2020)
Kei Kudo, Takuya Hashimoto, Junko Hashimoto, Ikuko Kozone, Noritaka Kagaya, Reiko Ueoka, Takehiro Nishimura, Mamoru Komatsu, Hikaru Suenaga, Haruo Ikeda, Teppei Kawahara
In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives. Nature communications 11 (1) (2020)
Takuya Hashimoto, Ikuko Kozone, Junko Hashimoto, Reiko Ueoka, Noritaka Kagaya, Manabu Fujie, Noriyuki Sato, Haruo Ikeda, Teppei Kawahara
Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908. The Journal of antibiotics 73 (3) (2019)
Ayumu Demachi, Ryuji Uchida, Shiho Arima, Tohru Nagamitsu, Junko Hashimoto, Mamoru Komatsu, Ikuko Kozone, Teppei Kawahara, Hiroshi Tomoda, Haruo Ikeda
An Unusual Extender Unit Is Incorporated into the Modular Polyketide Synthase of Scopranones Biosynthesis. Biochemistry 58 (50) (2019)
Masaya Kobayashi, Takeo Tomita, Teppei Kawahara, Makoto Nishiyama, Tomohisa Kuzuyama
An Unprecedented Cyclization Mechanism in the Biosynthesis of Carbazole Alkaloids in Streptomyces. Angewandte Chemie (International ed. in English) 58 (38) (2019)
Shohei Takase, Rumi Kurokawa, Yasumitsu Kondoh, Kaori Honda, Takehiro Suzuki, Teppei Kawahara, Haruo Ikeda, Naoshi Dohmae, Hiroyuki Osada, Teppei Kawahara, Tetsuo Kushiro, Minoru Yoshida, Ken Matsumoto
Mechanism of Action of Prethioviridamide, an Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptide with a Polythioamide Structure. ACS chemical biology 14 (8) (2019)
Anthony J Romo, Taro Shiraishi, Hideo Ikeuchi, Geng-Min Lin, Yujie Geng, Yu-Hsuan Lee, Priscilla H Liem, Tianlu Ma, Yasushi Ogasawara, Teppei Kawahara, Makoto Nishiyama, Tomohisa Kuzuyama, Hung-Wen Liu
The Amipurimycin and Miharamycin Biosynthetic Gene Clusters: Unraveling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics. Journal of the American Chemical Society 141 (36) (2019)
Kei Kudo, Hanae Koiwai, Noritaka Kagaya, Makoto Nishiyama, Tomohisa Kuzuyama, Teppei Kawahara, Haruo Ikeda
Comprehensive Derivatization of Thioviridamides by Heterologous Expression. ACS chemical biology 14 (6) (2019)
Danyao Du, Yohei Katsuyama, Teppei Kawahara, Yasuo Ohnishi
Reconstitution of a Type II Polyketide Synthase that Catalyzes Polyene Formation. Angewandte Chemie (International ed. in English) 57 (7) (2018)
Takuya Hashimoto, Junko Hashimoto, Ikuko Kozone, Keita Amagai, Teppei Kawahara, Shunji Takahashi, Haruo Ikeda, Teppei Kawahara
Biosynthesis of Quinolidomicin, the Largest Known Macrolide of Terrestrial Origin: Identification and Heterologous Expression of a Biosynthetic Gene Cluster over 200 kb. Organic letters 20 (24) (2018)