Konstantinos Tzelepis

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 11

Top Topics

Saccharomyces Cerevisiae

Top Venues

Nature communications

Science advances

Nature genetics

This page only lists publications with an associated author ORCID identifier.

Publications

James Russell, Konstantinos Tzelepis
A non-coding m 6 A reader promotes leukaemia. Nature cell biology (2023)
Katherine Sturgess, Eliza Yankova, M S Vijayabaskar, Tomoya Isobe, Justyna Rak, Iwo Kucinski, Melania Barile, Natalie A Webster, Maria Eleftheriou, Rebecca Hannah, Malgorzata Gozdecka, George S Vassiliou, Oliver Rausch, Nicola K Wilson, Berthold Göttgens, Konstantinos Tzelepis
Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages. Leukemia (2023)
Sigitas Mikutis, Maria Rebelo, Eliza Yankova, Muxin Gu, Cong Tang, Ana R Coelho, Mo Yang, Madoka E Hazemi, Marta Pires de Miranda, Maria Eleftheriou, Max Robertson, George S Vassiliou, David J Adams, J Pedro Simas, Francisco Corzana, John S Schneekloth, Konstantinos Tzelepis, Gonçalo J L Bernardes
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules. ACS central science 9 (5) (2023)
Keith Woodley, Laura S Dillingh, George Giotopoulos, Pedro Madrigal, Kevin M Rattigan, Céline Philippe, Vilma Dembitz, Aoife M S Magee, Ryan Asby, Louie N van de Lagemaat, Christopher Mapperley, Sophie C James, Jochen H M Prehn, Konstantinos Tzelepis, Kevin Rouault-Pierre, George S Vassiliou, Kamil R Kranc, G Vignir Helgason, Brian James Patrick Huntly, Paolo Gallipoli
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nature communications 14 (1) (2023)
Namshik Han, Woochang Hwang, Konstantinos Tzelepis, Patrick Schmerer, Eliza Yankova, Méabh MacMahon, Winnie Lei, Nicholas M Katritsis, Anika Liu, Ulrike Felgenhauer, Alison Schuldt, Rebecca Harris, Kathryn Chapman, Frank McCaughan, Friedemann Weber, Tony Kouzarides
Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies. Science advances 7 (27) (2021)
Adrien Leger, Paulo P Amaral, Luca Pandolfini, Charlotte Capitanchik, Federica Capraro, Valentina Miano, Valentina Migliori, Patrick Toolan-Kerr, Theodora Sideri, Anton J Enright, Konstantinos Tzelepis, Folkert Jacobus van Werven, Nicholas M Luscombe, Isaia Barbieri, Jernej Ule, Tomas W Fitzgerald, Ewan Birney, Tommaso Leonardi, Tony Kouzarides
RNA modifications detection by comparative Nanopore direct RNA sequencing. Nature communications 12 (1) (2021)
Eliza Yankova, Wesley Blackaby, Mark Albertella, Justyna Rak, Etienne De Braekeleer, Georgia Tsagkogeorga, Ewa S Pilka, Demetrios Aspris, Dan Leggate, Alan G Hendrick, Natalie A Webster, Byron Andrews, Richard Fosbeary, Patrick Guest, Nerea Irigoyen, Maria Eleftheriou, Malgorzata Gozdecka, Joao M L Dias, Andrew J Bannister, Binje Vick, Irmela Jeremias, George S Vassiliou, Oliver Rausch, Konstantinos Tzelepis, Tony Kouzarides
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature 593 (7860) (2021)
Suruchi Pacharne, Oliver M Dovey, Jonathan L Cooper, Muxin Gu, Mathias J Friedrich, Sandeep S Rajan, Maxim Barenboim, Grace Collord, M S Vijayabaskar, Hannes Ponstingl, Etienne D Braekeleer, Ruben Bautista, Milena Mazan, Roland Rad, Konstantinos Tzelepis, Penny Wright, Malgorzata Gozdecka, George S Vassiliou
SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML. Blood advances 5 (9) (2021)
Silvia Basilico, Xiaonan Wang, Alison Kennedy, Konstantinos Tzelepis, George Giotopoulos, Sarah J Kinston, Pedro M Quiros, Kim Wong, David J Adams, Larissa S Carnevalli, Brian James Patrick Huntly, George S Vassiliou, Fernando J Calero-Nieto, Berthold Göttgens
Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML. Nature communications 11 (1) (2020)
Yan Zi Au, Muxin Gu, Etienne De Braekeleer, Malgorzata Gozdecka, Demetrios Aspris, Yusuke Tarumoto, Jonathan Cooper, Jason S L Yu, Swee Hoe Ong, Xi Chen, Konstantinos Tzelepis, Brian James Patrick Huntly, George S Vassiliou, Kosuke Yusa
KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements. Leukemia 35 (4) (2020)
Malgorzata Gozdecka, Eshwar Meduri, Milena Mazan, Konstantinos Tzelepis, Monika Dudek, Andrew J Knights, Mercedes Calvo Pardo, Lu Yu, Jyoti S Choudhary, Emmanouil Metzakopian, Vivek Iyer, Haiyang Yun, Naomi Park, Ignacio Varela, Ruben Bautista, Grace Collord, Oliver Dovey, Dimitrios A Garyfallos, Etienne De Braekeleer, Saki Kondo, Jonathan Cooper, Berthold Göttgens, Lars Bullinger, Paul A Northcott, David Adams, George S Vassiliou, Brian James Patrick Huntly
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nature genetics 50 (6) (2018)