Kyriakos P Papadopoulos

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Topics

Advanced Cancer

Monoclonal Antibody

Top Venues

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical cancer research : an official journal of the American Association for Cancer Research

Cancer discovery

Journal for immunotherapy of cancer

This page only lists publications with an associated author ORCID identifier.

Publications

Omid Hamid, Karl D Lewis, Amy Weise, Meredith A McKean, Kyriakos P Papadopoulos, John Crown, Tae Min Kim, Dae Ho Lee, Sajeve S Thomas, Janice Mehnert, John Kaczmar, Nehal J Lakhani, Kevin B Kim, Mark Ross Middleton, Guilherme Rabinowits, Alexander I Spira, Melinda Yushak, Inderjit Mehmi, Fang Fang, Shuquan Chen, Jayakumar Mani, Vladimir Jankovic, Fang Wang, Nathalie Fiaschi, Laura Brennan, Anne J Paccaly, Sheila Masinde, Mark Salvati, Matthew G Fury, Glenn S Kroog, Israel Lowy, Giuseppe Gullo
Phase I Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced Melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Aditya Bardia, Ian E Krop, Takahiro Kogawa, Dejan Juric, Anthony W Tolcher, Erika Paige Hamilton, Toru Mukohara, Aaron E Lisberg, Toshio Shimizu, Alexander I Spira, Junji Tsurutani, Senthil Damodaran, Kyriakos P Papadopoulos, Jonathan Greenberg, Fumiaki Kobayashi, Hong Zebger-Gong, Rie Wong, Yui Kawasaki, Tadakatsu Nakamura, Funda Meric-Bernstam
Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (19) (2024)
Aditya Bardia, Ian E Krop, Takahiro Kogawa, Dejan Juric, Anthony W Tolcher, Erika Paige Hamilton, Toru Mukohara, Aaron E Lisberg, Toshio Shimizu, Alexander I Spira, Junji Tsurutani, Senthil Damodaran, Kyriakos P Papadopoulos, Jonathan Greenberg, Fumiaki Kobayashi, Hong Zebger-Gong, Rie Wong, Yui Kawasaki, Tadakatsu Nakamura, Funda Meric-Bernstam
Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Aditya Bardia, Ian E Krop, Takahiro Kogawa, Dejan Juric, Anthony W Tolcher, Erika Paige Hamilton, Toru Mukohara, Aaron E Lisberg, Toshio Shimizu, Alexander I Spira, Junji Tsurutani, Senthil Damodaran, Kyriakos P Papadopoulos, Jonathan Greenberg, Fumiaki Kobayashi, Hong Zebger-Gong, Rie Wong, Yui Kawasaki, Tadakatsu Nakamura, Funda Meric-Bernstam
Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (19) (2024)
Rona Yaeger, Meredith A McKean, Rizwan Haq, J Thaddeus Beck, Matthew H Taylor, Jonathan Eliezer Cohen, Daniel W Bowles, Shirish M Gadgeel, Catalin Mihalcioiu, Kyriakos P Papadopoulos, Eli L Diamond, Keren B Sturtz, Gang Feng, Stefanie K Drescher, Micaela B Reddy, Bhaswati Sengupta, Arnab Kumar Maity, Suzy A Brown, Anurag Singh, Eric N Brown, Brian R Baer, Jim Wong, Tung-Chung Mou, Wen-I Wu, Dean R Kahn, Sunyana Gadal, Neal X Rosen, John J Gaudino, Patrice A Lee, Dylan P Hartley, S Michael Rothenberg
A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation. Cancer discovery (2024)
Aditya Bardia, Ian E Krop, Takahiro Kogawa, Dejan Juric, Anthony W Tolcher, Erika Paige Hamilton, Toru Mukohara, Aaron E Lisberg, Toshio Shimizu, Alexander I Spira, Junji Tsurutani, Senthil Damodaran, Kyriakos P Papadopoulos, Jonathan Greenberg, Fumiaki Kobayashi, Hong Zebger-Gong, Rie Wong, Yui Kawasaki, Tadakatsu Nakamura, Funda Meric-Bernstam
Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (19) (2024)
Omid Hamid, Karl D Lewis, Amy Weise, Meredith A McKean, Kyriakos P Papadopoulos, John Crown, Tae Min Kim, Dae Ho Lee, Sajeve S Thomas, Janice Mehnert, John Kaczmar, Nehal J Lakhani, Kevin B Kim, Mark Ross Middleton, Guilherme Rabinowits, Alexander I Spira, Melinda Yushak, Inderjit Mehmi, Fang Fang, Shuquan Chen, Jayakumar Mani, Vladimir Jankovic, Fang Wang, Nathalie Fiaschi, Laura Brennan, Anne J Paccaly, Sheila Masinde, Mark Salvati, Matthew G Fury, Glenn S Kroog, Israel Lowy, Giuseppe Gullo
Phase I Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced Melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (24) (2024)
Omid Hamid, Karl D Lewis, Amy Weise, Meredith A McKean, Kyriakos P Papadopoulos, John Crown, Tae Min Kim, Dae Ho Lee, Sajeve S Thomas, Janice Mehnert, John Kaczmar, Nehal J Lakhani, Kevin B Kim, Mark Ross Middleton, Guilherme Rabinowits, Alexander I Spira, Melinda Yushak, Inderjit Mehmi, Fang Fang, Shuquan Chen, Jayakumar Mani, Vladimir Jankovic, Fang Wang, Nathalie Fiaschi, Laura Brennan, Anne J Paccaly, Sheila Masinde, Mark Salvati, Matthew G Fury, Glenn S Kroog, Israel Lowy, Giuseppe Gullo
Phase I Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced Melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (24) (2024)
Aditya Bardia, Ian E Krop, Takahiro Kogawa, Dejan Juric, Anthony W Tolcher, Erika Paige Hamilton, Toru Mukohara, Aaron E Lisberg, Toshio Shimizu, Alexander I Spira, Junji Tsurutani, Senthil Damodaran, Kyriakos P Papadopoulos, Jonathan Greenberg, Fumiaki Kobayashi, Hong Zebger-Gong, Rie Wong, Yui Kawasaki, Tadakatsu Nakamura, Funda Meric-Bernstam
Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2- and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (19) (2024)
Omid Hamid, Karl D Lewis, Amy Weise, Meredith A McKean, Kyriakos P Papadopoulos, John Crown, Tae Min Kim, Dae Ho Lee, Sajeve S Thomas, Janice Mehnert, John Kaczmar, Nehal J Lakhani, Kevin B Kim, Mark Ross Middleton, Guilherme Rabinowits, Alexander I Spira, Melinda Yushak, Inderjit Mehmi, Fang Fang, Shuquan Chen, Jayakumar Mani, Vladimir Jankovic, Fang Wang, Nathalie Fiaschi, Laura Brennan, Anne J Paccaly, Sheila Masinde, Mark Salvati, Matthew G Fury, Glenn S Kroog, Israel Lowy, Giuseppe Gullo
Phase I Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced Melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (24) (2024)
Lars D Engstrom, Ruth Aranda, Laura Waters, Krystal Moya, Vickie Bowcut, Laura Vegar, David Trinh, Allan Hebbert, Christopher R Smith, Svitlana Kulyk, J David Lawson, Quanyuan He, Laura D Hover, Julio Fernandez-Banet, Jill Hallin, Darin Vanderpool, David M Briere, Alice Blaj, Matthew A Marx, Jordi Rodon Ahnert, Michael D Offin, Kathryn C Arbour, Melissa Lynne Johnson, David J Kwiatkowski, Pasi A Janne, Candace L Haddox, Kyriakos P Papadopoulos, Jason T Henry, Konstantinos Leventakos, James G Christensen, Ronald Shazer, Peter Olson
MRTX1719 is an MTA-cooperative PRMT5 inhibitor that exhibits synthetic lethality in preclinical models and patients with MTAP deleted cancer. Cancer discovery (2023)
Timothy Anthony Yap, Justin F Gainor, Margaret K Callahan, Gerald S Falchook, Russell K Pachynski, Patricia LoRusso, Shivaani Kummar, Geoffrey T Gibney, Howard A Burris, Scott S Tykodi, Osama E Rahma, Tanguy Y Seiwert, Kyriakos P Papadopoulos, Mariela Blum Murphy, Haeseong Park, Amanda Hanson, Yasmin Hashambhoy-Ramsay, Lara McGrath, Ellen Hooper, Xiaoying Xiao, Heather Cohen, Martin Fan, Daniel Felitsky, Courtney Hart, Rachel McComb, Karen Brown, Ali Sepahi, Judith Jimenez, Weidong Zhang, Johan Baeck, Haley Laken, Richard Murray, Elizabeth Trehu, Christopher J Harvey
First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab: ICOS-High CD4 T-Cell Populations and Predictors of Response. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Sai-Hong Ignatius Ou, Pasi A Janne, Ticiana A Leal, Igor I Rybkin, Joshua K Sabari, Minal A Barve, Lyudmila Bazhenova, Melissa Lynne Johnson, Karen L Velastegui, Cornelius Cilliers, James G Christensen, Xiaohong Yan, Richard C Chao, Kyriakos P Papadopoulos
First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRAS G12C Solid Tumors (KRYSTAL-1). Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (23) (2022)
Timothy Anthony Yap, Patricia M LoRusso, Deborah J Wong, Siwen Hu-Lieskovan, Kyriakos P Papadopoulos, Josefin-Beate Holz, Urszula Grabowska, Cristian Gradinaru, Kin-Mei Leung, Sylwia Marshall, Claire S Reader, Roslin Russell, Richard C A Sainson, Claire J Seal, Christopher J Shepherd, Fiona Germaschewski, Daniel R Gliddon, Omer Stern, Lesley Young, Neil Brewis, Louis Kayitalire, Michelle Morrow
A Phase 1 first-in-human study of FS118, a tetravalent bispecific antibody targeting LAG-3 and PD-L1 in patients with advanced cancer and PD-L1 resistance. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Aung Naing, Joseph P Eder, Sarina A Piha-Paul, Claude Gimmi, Elizabeth Hussey, Sen Zhang, Vera Hildebrand, Vinayak Hosagrahara, Christina Habermehl, Jacques Moisan, Kyriakos P Papadopoulos
Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase 2, in patients with advanced solid tumors. Journal for immunotherapy of cancer 8 (2) (2021)
Albiruni Ra Razak, James M Cleary, Victor Moreno, Michael Boyer, Emiliano Calvo Aller, William Edenfield, Jeanne Tie, R Donald Harvey, Annemie Rutten, Manish A Shah, Anthony J Olszanski, Dirk Jäger, Nehal Lakhani, David P Ryan, Erik Rasmussen, Gloria Juan, Hansen Wong, Neelesh Soman, Marie-Anne Damiette Smit, Dirk Nagorsen, Kyriakos P Papadopoulos
Safety and efficacy of AMG 820, an anti-colony-stimulating factor 1 receptor antibody, in combination with pembrolizumab in adults with advanced solid tumors. Journal for immunotherapy of cancer 8 (2) (2021)
Kyriakos P Papadopoulos, Karen Autio, Talia Golan, Konstantin Dobrenkov, Elliot Chartash, Qiusheng Chen, Richard Wnek, Georgina V Long
Phase I Study of MK-4166, an Anti-human Glucocorticoid-Induced TNF Receptor Antibody, Alone or with Pembrolizumab in Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (7) (2020)
Kyriakos P Papadopoulos, Erkut Hasan Borazanci, Alice T Shaw, Ryohei Katayama, Yuki Shimizu, Viola W Zhu, Thomas Yang Sun, Heather A Wakelee, Russell W Madison, Alexa B Schrock, Giorgio Senaldi, Naoki Nakao, Hiroyuki Hanzawa, Masaya Tachibana, Takeshi Isoyama, Kenji Nakamaru, Chenhui Deng, Meijing Li, Frank Fan, Qinying Zhao, Yanfei Gao, Takashi Seto, Pasi A Jänne, Sai-Hong Ignatius Ou
U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (18) (2020)
Monica M Mita, Patricia M LoRusso, Kyriakos P Papadopoulos, Michael S Gordon, Alain C Mita, Roberta Ferraldeschi, Harold Keer, Aram Oganesian, Xiang Yao Su, Simone Jueliger, Anthony W Tolcher
A Phase I Study of ASTX660, an Antagonist of Inhibitors of Apoptosis Proteins, in Adults with Advanced Cancers or Lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (12) (2020)
Kyriakos P Papadopoulos, Nehal Lakhani, Gerald S Falchook, Gosia Riley, Johan Baeck, Karen S Brown, Gilad Gordon, Lidya Le, Judy S Wang
Phase I, first-in-human trial of programmed cell death receptor-1 (PD-1) inhibitor, JTX-4014, in adult patients with advanced, refractory, solid tumors. Cancer immunology, immunotherapy : CII 70 (3) (2020)
Jill Hallin, Lars D Engstrom, Lauren Hargis, Andrew Calinisan, Ruth Aranda, David M Briere, Niranjan Sudhakar, Vickie Bowcut, Brian R Baer, Joshua A Ballard, Michael R Burkard, Jay B Fell, John P Fischer, Guy P Vigers, Jenny Y Xue, Sole Gatto, Julio Fernandez-Banet, Adam Pavlicek, Karen Velastagui, Richard C Chao, Jeremy Barton, Mariaelena Pierobon, Elisa Baldelli, Emanuel F Patricoin, Douglas P Cassidy, Matthew A Marx, Igor I Rybkin, Melissa L Johnson, Sai-Hong Ignatius Ou, Piro Lito, Kyriakos P Papadopoulos, Pasi A Jänne, Peter Olson, James G Christensen
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients. Cancer discovery 10 (1) (2019)
Kyriakos P Papadopoulos, Melissa L Johnson, Albert C Lockhart, Kathleen Moore, Gerald S Falchook, Silvia C Formenti, Aung Naing, Richard D Carvajal, Lee S Rosen, Glen J Weiss, Rom S Leidner, Jingjin Li, Anne Paccaly, Minjie Feng, Elizabeth Stankevich, Israel Lowy, Matthew G Fury, Marka R Crittenden
First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low-dose Cyclophosphamide in Patients with Advanced Malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (5) (2019)
Drew W Rasco, Kyriakos P Papadopoulos, Michael Pourdehnad, Anita K Gandhi, Patrick R Hagner, Yan Li, Xin Wei, Rajesh Chopra, Kristen Hege, Jorge DiMartino, Kent Shih
A First-in-Human Study of Novel Cereblon Modulator Avadomide (CC-122) in Advanced Malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (1) (2018)
Emiliano Cocco, F Javier Carmona, Pedram Razavi, Helen H Won, Yanyan Cai, Valentina Rossi, Carmen Chan, James Cownie, Joanne Soong, Eneda Toska, Sophie G Shifman, Ivana Sarotto, Peter Savas, Michael J Wick, Kyriakos P Papadopoulos, Alyssa Moriarty, Richard E Cutler, Francesca Avogadri-Connors, Alshad S Lalani, Richard P Bryce, Sarat Chandarlapaty, David M Hyman, David B Solit, Valentina Boni, Sherene Loi, Jose Baselga, Michael F Berger, Filippo Montemurro, Maurizio Scaltriti
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2). Science signaling 11 (551) (2018)
Krista Kinneer, John Meekin, Arnaud C Tiberghien, Yu-Tzu Tai, Sandrina Phipps, Christine Mione Kiefer, Marlon C Rebelatto, Nazzareno Dimasi, Alyssa Moriarty, Kyriakos P Papadopoulos, Sriram Sridhar, Stephen J Gregson, Michael J Wick, Luke Masterson, Kenneth C Anderson, Ronald Herbst, Philip W Howard, David A Tice
SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked Maytansinoid and Pyrrolobenzodiazepine Warheads. Clinical cancer research : an official journal of the American Association for Cancer Research 24 (24) (2018)
Amita Patnaik, Michael Gordon, Frank Tsai, Kyriakos P Papadopoulos, Drew Rasco, Muralidhar Beeram, Siqing Fu, Filip Janku, Scott M Hynes, Sushma R Gundala, Melinda D Willard, Wei Zhang, Aimee Bence Lin, David S Hong
A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer. Cancer chemotherapy and pharmacology 82 (3) (2018)