Helge B Bode

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 79

Top Venues

Angewandte Chemie (International ed. in English)

ACS synthetic biology

Nature chemistry

Nature microbiology

Goethe Universität Frankfurt

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Goethe Universität Frankfurt

Germany

Molekulare Biotechnologie :: Fachbereich Biowissenschaften

Publications

Leopoldo Palma, Laureano Frizzo, Sebastian Kaiser, Colin Berry, Primitivo Caballero, Helge B Bode, Eleodoro Eduardo Del Valle
Genome Sequence Analysis of Native Xenorhabdus Strains Isolated from Entomopathogenic Nematodes in Argentina. Toxins 16 (2) (2024)
Leonard Präve, Carsten E Seyfert, Kenan A J Bozhüyük, Emilie Racine, Rolf Müller, Helge B Bode
Investigation of the Odilorhabdin Biosynthetic Gene Cluster Using NRPS Engineering. Angewandte Chemie (International ed. in English) 63 (33) (2024)
Leopoldo Palma, Laureano Frizzo, Sebastian Kaiser, Colin Berry, Primitivo Caballero, Helge B Bode, Eleodoro Eduardo Del Valle
Genome Sequence Analysis of Native Xenorhabdus Strains Isolated from Entomopathogenic Nematodes in Argentina. Toxins 16 (2) (2024)
Alexander Rill, Lei Zhao, Helge B Bode
Genetic toolbox for Photorhabdus and Xenorhabdus: pSEVA based heterologous expression systems and CRISPR/Cpf1 based genome editing for rapid natural product profiling. Microbial cell factories 23 (1) (2024)
Kenan A J Bozhüyük, Leonard Präve, Carsten Kegler, Leonie Schenk, Sebastian Kaiser, Christian Schelhas, Yan-Ni Shi, Wolfgang Kuttenlochner, Max Schreiber, Joshua Kandler, Mohammad Alanjary, T M Mohiuddin, Michael Groll, Georg K A Hochberg, Helge B Bode
Evolution-inspired engineering of nonribosomal peptide synthetases. Science (New York, N.Y.) 383 (6689) (2024)
Kenan A J Bozhüyük, Leonard Präve, Carsten Kegler, Leonie Schenk, Sebastian Kaiser, Christian Schelhas, Yan-Ni Shi, Wolfgang Kuttenlochner, Max Schreiber, Joshua Kandler, Mohammad Alanjary, T M Mohiuddin, Michael Groll, Georg K A Hochberg, Helge B Bode
Evolution-inspired engineering of nonribosomal peptide synthetases. Science (New York, N.Y.) 383 (6689) (2024)
Leonard Präve, Carsten E Seyfert, Kenan A J Bozhüyük, Emilie Racine, Rolf Müller, Helge B Bode
Investigation of the Odilorhabdin Biosynthetic Gene Cluster Using NRPS Engineering. Angewandte Chemie (International ed. in English) (2024)
Kenan A J Bozhüyük, Leonard Präve, Carsten Kegler, Leonie Schenk, Sebastian Kaiser, Christian Schelhas, Yan-Ni Shi, Wolfgang Kuttenlochner, Max Schreiber, Joshua Kandler, Mohammad Alanjary, T M Mohiuddin, Michael Groll, Georg K A Hochberg, Helge B Bode
Evolution-inspired engineering of nonribosomal peptide synthetases. Science (New York, N.Y.) 383 (6689) (2024)
Leopoldo Palma, Laureano Frizzo, Sebastian Kaiser, Colin Berry, Primitivo Caballero, Helge B Bode, Eleodoro Eduardo Del Valle
Genome Sequence Analysis of Native Xenorhabdus Strains Isolated from Entomopathogenic Nematodes in Argentina. Toxins 16 (2) (2024)
Alexander Rill, Lei Zhao, Helge B Bode
Genetic toolbox for Photorhabdus and Xenorhabdus: pSEVA based heterologous expression systems and CRISPR/Cpf1 based genome editing for rapid natural product profiling. Microbial cell factories 23 (1) (2024)
Leopoldo Palma, Laureano Frizzo, Sebastian Kaiser, Colin Berry, Primitivo Caballero, Helge B Bode, Eleodoro Eduardo Del Valle
Genome Sequence Analysis of Native Xenorhabdus Strains Isolated from Entomopathogenic Nematodes in Argentina. Toxins 16 (2) (2024)
Alexander Rill, Lei Zhao, Helge B Bode
Genetic toolbox for Photorhabdus and Xenorhabdus: pSEVA based heterologous expression systems and CRISPR/Cpf1 based genome editing for rapid natural product profiling. Microbial cell factories 23 (1) (2024)
Nadya Abbood, Juliana Effert, Kenan A J Bozhüyük, Helge B Bode
Guidelines for Optimizing Type S Nonribosomal Peptide Synthetases. ACS synthetic biology (2023)
Nadya Abbood, Tien Duy Vo, Jonas Watzel, Kenan A J Bozhueyuek, Helge B Bode
Type S Non-Ribosomal Peptide Synthetases for the Rapid Generation of Tailormade Peptide Libraries. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (26) (2022)
Xiaofeng Cai, Alexander Rill, Helge B Bode
Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides. ACS synthetic biology 12 (1) (2022)
Desalegne Abebew, Fatemeh S Sayedain, Edna Bode, Helge B Bode
Uncovering Nematicidal Natural Products from Xenorhabdus Bacteria. Journal of agricultural and food chemistry 70 (2) (2022)
Xiaofeng Cai, Alexander Rill, Helge B Bode
Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides. ACS synthetic biology 12 (1) (2022)
Xiaofeng Cai, Alexander Rill, Helge B Bode
Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides. ACS synthetic biology (2022)
Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Helge B Bode
Cleavage Off-Loading and Post-assembly-Line Conversions Yield Products with Unusual Termini during Biosynthesis. ACS chemical biology 17 (8) (2022)
Xiaofeng Cai, Alexander Rill, Helge B Bode
Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides. ACS synthetic biology 12 (1) (2022)
Yi-Ming Shi, Jan J Crames, Laura Czech, Kenan A J Bozhüyük, Yan-Ni Shi, Merle Hirschmann, Stefanie Lamberth, Peter Claus, Nicole Paczia, Christian Rückert, Jörn Kalinowski, Gert Bange, Helge B Bode
Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate-Containing Natural Products in Diverse Bacteria. Angewandte Chemie (International ed. in English) (2022)
Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Shabbir Ahmed, Desalegne Abebew, Nicholas J Tobias, Peter Grün, Jan J Crames, Laura Pöschel, Wolfgang Kuttenlochner, Christian Richter, Jennifer Herrmann, Daniel Krug, Aunchalee Thanwisai, Sacha J Pidot, Timothy P Stinear, Michael Groll, Yong-Gyun Kim, Helge B Bode
Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria. Nature chemistry 14 (6) (2022)
Xiaofeng Cai, Alexander Rill, Helge B Bode
Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides. ACS synthetic biology 12 (1) (2022)
Xiaofeng Cai, Alexander Rill, Helge B Bode
Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides. ACS synthetic biology 12 (1) (2022)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry 5 (10) (2021)
Sebastian L Wenski, Natalie Berghaus, Nadine Keller, Helge B Bode
Structure and biosynthesis of deoxy-polyamine in Xenorhabdus bovienii. Journal of industrial microbiology & biotechnology 48 (3-4) (2021)
Garima Singh, Anjuli Calchera, Meike Schulz, Moritz Drechsler, Helge B Bode, Imke Schmitt, Francesco Dal Grande
Climate-specific biosynthetic gene clusters in populations of a lichen-forming fungus. Environmental microbiology 23 (8) (2021)
Lei Zhao, Camille Le Chapelain, Alexander O Brachmann, Marcel Kaiser, Michael Groll, Helge B Bode
Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii. Chembiochem : a European journal of chemical biology 22 (9) (2021)
Tien Duy Vo, Christoph Spahn, Mike Heilemann, Helge B Bode
Microbial Cationic Peptides as a Natural Defense Mechanism against Insect Antimicrobial Peptides. ACS chemical biology 16 (3) (2021)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry 5 (10) (2021)
Bahar Behsaz, Edna Bode, Alexey Gurevich, Yan-Ni Shi, Florian Grundmann, Deepa Acharya, Andrés Mauricio Caraballo-Rodriguez, Amina Bouslimani, Morgan Panitchpakdi, Annabell Linck, Changhui Guan, Julia Oh, Pieter C Dorrestein, Helge B Bode, Pavel A Pevzner, Hosein Mohimani
Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery. Nature communications 12 (1) (2021)
Kenan A J Bozhueyuek, Jonas Watzel, Nadya Abbood, Helge B Bode
Synthetic Zippers as an Enabling Tool for Engineering of Non-Ribosomal Peptide Synthetases*. Angewandte Chemie (International ed. in English) 60 (32) (2021)
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth M Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Daniel Krug
Towards the sustainable discovery and development of new antibiotics. Nature reviews. Chemistry (2021)
Jonas Watzel, Sepas Sarawi, Elke Duchardt-Ferner, Helge B Bode, Jens Wöhnert
NMR resonance assignments for a docking domain pair with an attached thiolation domain from the PAX peptide-producing NRPS from Xenorhabdus cabanillasii. Biomolecular NMR assignments 15 (1) (2021)
Jonas Watzel, Elke Duchardt-Ferner, Sepas Sarawi, Helge B Bode, Jens Wöhnert
Cooperation between a T Domain and a Minimal C-Terminal Docking Domain to Enable Specific Assembly in a Multiprotein NRPS. Angewandte Chemie (International ed. in English) 60 (25) (2021)
Bahar Behsaz, Edna Bode, Alexey Gurevich, Yan-Ni Shi, Florian Grundmann, Deepa Acharya, Andrés Mauricio Caraballo-Rodriguez, Amina Bouslimani, Morgan Panitchpakdi, Annabell Linck, Changhui Guan, Julia Oh, Pieter C Dorrestein, Helge B Bode, Pavel A Pevzner, Hosein Mohimani
Publisher Correction: Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery. Nature communications 12 (1) (2021)
Ilka Siebels, Sarah Nowak, Christina S Heil, Peter Tufar, Niña S Cortina, Helge B Bode, Martin Grininger
Cell-Free Synthesis of Natural Compounds from Genomic DNA of Biosynthetic Gene Clusters. ACS synthetic biology 9 (9) (2020)
Carsten Kegler, Helge B Bode
Artificial Splitting of a Non-Ribosomal Peptide Synthetase by Inserting Natural Docking Domains. Angewandte Chemie (International ed. in English) 59 (32) (2020)
Nick Neubacher, Nicholas J Tobias, Michaela Huber, Xiaofeng Cai, Timo Glatter, Sacha J Pidot, Timothy P Stinear, Anna Lena Lütticke, Kai Pappenfort, Helge B Bode
Symbiosis, virulence and natural-product biosynthesis in entomopathogenic bacteria are regulated by a small RNA. Nature microbiology 5 (12) (2020)
Andreas Tietze, Yan-Ni Shi, Max Kronenwerth, Helge B Bode
Nonribosomal Peptides Produced by Minimal and Engineered Synthetases with Terminal Reductase Domains. Chembiochem : a European journal of chemical biology 21 (19) (2020)
Sebastian L Wenski, Harun Cimen, Natalie Berghaus, Sebastian W Fuchs, Selcuk Hazir, Helge B Bode
Fabclavine diversity in Xenorhabdus bacteria. Beilstein journal of organic chemistry 16 (2020)
Alois Bräuer, Qiuqin Zhou, Gina L C Grammbitter, Maximilian Schmalhofer, Michael Rühl, Ville R I Kaila, Helge B Bode, Michael Groll
Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis. Nature chemistry 12 (8) (2020)
Jonas Watzel, Carolin Hacker, Elke Duchardt-Ferner, Helge B Bode, Jens Wöhnert
A New Docking Domain Type in the Peptide-Antimicrobial-Xenorhabdus Peptide Producing Nonribosomal Peptide Synthetase from Xenorhabdus bovienii. ACS chemical biology 15 (4) (2020)
Lei Zhao, Tien Duy Vo, Marcel Kaiser, Helge B Bode
Phototemtide A, a Cyclic Lipopeptide Heterologously Expressed from Photorhabdus temperata Meg1, Shows Selective Antiprotozoal Activity. Chembiochem : a European journal of chemical biology 21 (9) (2020)
Alison E Murray, John Freudenstein, Simonetta Gribaldo, Roland Hatzenpichler, Philip Hugenholtz, Peter Kämpfer, Konstantinos T Konstantinidis, Christopher E Lane, R Thane Papke, Donovan H Parks, Ramon Rossello-Mora, Matthew B Stott, Iain C Sutcliffe, J Cameron Thrash, Stephanus N Venter, William B Whitman, Silvia G Acinas, Rudolf I Amann, Karthik Anantharaman, Jean Armengaud, Brett J Baker, Roman A Barco, Helge B Bode, Eric S Boyd, Carrie L Brady, Paul Carini, Patrick S G Chain, Daniel R Colman, Kristen M DeAngelis, Maria Asuncion de Los Rios, Paulina Estrada-de Los Santos, Christopher A Dunlap, Jonathan A Eisen, David Emerson, Thijs J G Ettema, Damien Eveillard, Peter R Girguis, Ute Hentschel, James T Hollibaugh, Laura A Hug, William P Inskeep, Elena P Ivanova, Hans-Peter Klenk, Wen-Jun Li, Karen G Lloyd, Frank E Löffler, Thulani Peter Makhalanyane, Duane P Moser, Takuro Nunoura, Marike Palmer, Victor Parro, Carlos Pedrós-Alió, Alexander J Probst, Theo H M Smits, Andrew D Steen, Emma T Steenkamp, Anja Spang, Frank J Stewart, James M Tiedje, Peter Vandamme, Michael Wagner, Feng-Ping Wang, Pablo Yarza, Brian P Hedlund, Anna-Louise Reysenbach
Author Correction: Roadmap for naming uncultivated Archaea and Bacteria. Nature microbiology (2020)
Ricardo Alberto Ruiz Machado, Lisa Thönen, Carla C M Arce, Vanitha Theepan, Fausto Prada, Daniel Wüthrich, Christelle Aurélie Maud Robert, Evangelia Vogiatzaki, Yi-Ming Shi, Olivier P Schaeren, Matheus Notter, Rémy Bruggmann, Siegfried Hapfelmeier, Helge B Bode, Matthias Erb
Engineering bacterial symbionts of nematodes improves their biocontrol potential to counter the western corn rootworm. Nature biotechnology 38 (5) (2020)
Alison E Murray, John Freudenstein, Simonetta Gribaldo, Roland Hatzenpichler, Philip Hugenholtz, Peter Kämpfer, Konstantinos T Konstantinidis, Christopher E Lane, R Thane Papke, Donovan H Parks, Ramon Rossello-Mora, Matthew B Stott, Iain C Sutcliffe, J Cameron Thrash, Stephanus N Venter, William B Whitman, Silvia G Acinas, Rudolf I Amann, Karthik Anantharaman, Jean Armengaud, Brett J Baker, Roman A Barco, Helge B Bode, Eric S Boyd, Carrie L Brady, Paul Carini, Patrick S G Chain, Daniel R Colman, Kristen M DeAngelis, Maria Asuncion de Los Rios, Paulina Estrada-de Los Santos, Christopher A Dunlap, Jonathan A Eisen, David Emerson, Thijs J G Ettema, Damien Eveillard, Peter R Girguis, Ute Hentschel, James T Hollibaugh, Laura A Hug, William P Inskeep, Elena P Ivanova, Hans-Peter Klenk, Wen-Jun Li, Karen G Lloyd, Frank E Löffler, Thulani Peter Makhalanyane, Duane P Moser, Takuro Nunoura, Marike Palmer, Victor Parro, Carlos Pedrós-Alió, Alexander J Probst, Theo H M Smits, Andrew D Steen, Emma T Steenkamp, Anja Spang, Frank J Stewart, James M Tiedje, Peter Vandamme, Michael Wagner, Feng-Ping Wang, Pablo Yarza, Brian P Hedlund, Anna-Louise Reysenbach
Roadmap for naming uncultivated Archaea and Bacteria. Nature microbiology 5 (8) (2020)
Jana K Sonner, Melanie Keil, Maren Falk-Paulsen, Neha Mishra, Ateequr Rehman, Magdalena Kramer, Katrin Deumelandt, Julian Röwe, Khwab Sanghvi, Lara Wolf, Anna von Landenberg, Hendrik Wolff, Richa Bharti, Iris Oezen, Tobias V Lanz, Florian Wanke, Yilang Tang, Ines Brandao, Soumya R Mohapatra, Lisa Epping, Alexandra Grill, Ralph Röth, Beate Niesler, Sven G Meuth, Christiane A Opitz, Jürgen G Okun, Christian Reinhardt, Florian C Kurschus, Wolfgang Wick, Helge B Bode, Philip Rosenstiel, Michael Platten
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology. Nature communications 10 (1) (2019)
Gina L C Grammbitter, Maximilian Schmalhofer, Kudratullah Karimi, Yi-Ming Shi, Tim A Schöner, Nicholas J Tobias, Nina Morgner, Michael Groll, Helge B Bode
An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments. Journal of the American Chemical Society 141 (42) (2019)
Sebastian L Wenski, Diana Kolbert, Gina L C Grammbitter, Helge B Bode
Fabclavine biosynthesis in X. szentirmaii: shortened derivatives and characterization of the thioester reductase FclG and the condensation domain-like protein FclL. Journal of industrial microbiology & biotechnology 46 (3-4) (2019)
Xiaofeng Cai, Lei Zhao, Helge B Bode
Reprogramming Promiscuous Nonribosomal Peptide Synthetases for Production of Specific Peptides. Organic letters 21 (7) (2019)
Frank Wesche, Hélène Adihou, Thomas A Wichelhaus, Helge B Bode
Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila. Beilstein journal of organic chemistry 15 (2019)
Ruth Schmidt, Dana Ulanova, Lukas Y Wick, Helge B Bode, Paolina Garbeva
Microbe-driven chemical ecology: past, present and future. The ISME journal 13 (11) (2019)
Edna Bode, Antje K Heinrich, Merle Hirschmann, Desalegne Abebew, Yan-Ni Shi, Tien Duy Vo, Frank Wesche, Yi-Ming Shi, Peter Grün, Svenja Simonyi, Nadine Keller, Yvonne Engel, Sebastian Wenski, Reuel Bennet, Sophie Beyer, Iris Bischoff, Anthony Buaya, Sophie Brandt, Ibrahim Cakmak, Harun Cimen, Simone Eckstein, Denia Frank, Robert Fürst, Martin Gand, Gerd Geisslinger, Selcuk Hazir, Marina Henke, Ralf Heermann, Virginie Lecaudey, Wilhelm Schäfer, Susanne Schiffmann, Anja Schüffler, Rebecca Schwenk, Marisa Skaljac, Eckhard Thines, Marco Thines, Thomas Ulshöfer, Andreas Vilcinskas, Thomas A Wichelhaus, Helge B Bode
Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing. Angewandte Chemie (International ed. in English) 58 (52) (2019)
Kenan A J Bozhüyük, Annabell Linck, Andreas Tietze, Janik Kranz, Frank Wesche, Sarah Nowak, Florian Fleischhacker, Yan-Ni Shi, Peter Grün, Helge B Bode
Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains. Nature chemistry 11 (7) (2019)
Nicholas J Tobias, César Parra-Rojas, Yan-Ni Shi, Yi-Ming Shi, Svenja Simonyi, Aunchalee Thanwisai, Apichat Vitta, Narisara Chantratita, Esteban A Hernandez-Vargas, Helge B Bode
Cyclo(tetrahydroxybutyrate) production is sufficient to distinguish between Xenorhabdus and Photorhabdus isolates in Thailand. Environmental microbiology 21 (8) (2019)
Lei Zhao, Ryan Musumba Awori, Marcel Kaiser, Jonathan Groß, Jason Sirleaf, Helge B Bode
Structure, Biosynthesis, and Bioactivity of Photoditritide from Photorhabdus temperata Meg1. Journal of natural products 82 (12) (2019)
Yan-Ni Shi, Stefan Pusch, Yi-Ming Shi, Christian Richter, Jose G Maciá-Vicente, Harald Schwalbe, Marcel Kaiser, Jason Sirleaf, Helge B Bode
(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp. The Journal of organic chemistry 84 (17) (2019)
Nicholas J Tobias, Jannis Brehm, Darko Kresovic, Sophie Brameyer, Helge B Bode, Ralf Heermann
New Vocabulary for Bacterial Communication. Chembiochem : a European journal of chemical biology 21 (6) (2019)
Yi-Ming Shi, Alexander O Brachmann, Margaretha A Westphalen, Nick Neubacher, Nicholas J Tobias, Helge B Bode
Dual phenazine gene clusters enable diversification during biosynthesis. Nature chemical biology 15 (4) (2019)
Qiuqin Zhou, Alois Bräuer, Hélène Adihou, Maximilian Schmalhofer, Patricia Saura, Gina L C Grammbitter, Ville R I Kaila, Michael Groll, Helge B Bode
Molecular mechanism of polyketide shortening in anthraquinone biosynthesis of Photorhabdus luminescens. Chemical science 10 (25) (2019)
Ariful Hasan, Hyun-Suk Yeom, Jaewook Ryu, Helge B Bode, Yonggyun Kim
Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptor. Scientific reports 9 (1) (2019)
Gaoyan Wang, Zhiying Zhao, Jing Ke, Yvonne Engel, Yi-Ming Shi, David Robinson, Kerem Bingol, Zheyun Zhang, Benjamin Bowen, Katherine Louie, Bing Wang, Robert Evans, Yu Miyamoto, Kelly Cheng, Suzanne M Kosina, Markus de Raad, Leslie Silva, Alicia Luhrs, Andrea Lubbe, David W Hoyt, Charles Francavilla, Hiroshi Otani, Samuel Deutsch, Nancy M Washton, Edward M Rubin, Nigel J Mouncey, Axel Visel, Trent R Northen, Jan-Fang Cheng, Helge B Bode, Yasuo Yoshikuni
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria. Nature microbiology 4 (12) (2019)
Laura Drummond, Max J Kschowak, Jürgen Breitenbach, Hendrik Wolff, Yi-Ming Shi, Jens Schrader, Helge B Bode, Gerhard Sandmann, Markus Buchhaupt
Expanding the Isoprenoid Building Block Repertoire with an IPP Methyltransferase from Streptomyces monomycini. ACS synthetic biology 8 (6) (2019)
Carolin Hacker, Xiaofeng Cai, Carsten Kegler, Lei Zhao, A Katharina Weickhmann, Jan Philip Wurm, Helge B Bode, Jens Wöhnert
Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nature communications 9 (1) (2018)
Hendrik Wolff, Helge B Bode
The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis. PloS one 13 (3) (2018)
Yi-Ming Shi, Christian Richter, Victoria L Challinor, Peter Grün, Antonio Girela Del Rio, Marcel Kaiser, Anja Schüffler, Meike Piepenbring, Harald Schwalbe, Helge B Bode
Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus. Organic letters 20 (6) (2018)
Frank Wesche, Hélène Adihou, Astrid Kaiser, Mario Wurglics, Manfred Schubert-Zsilavecz, Marcel Kaiser, Helge B Bode
Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides. Journal of medicinal chemistry 61 (9) (2018)
Karl G Thieme, Jennifer Gerke, Christoph Sasse, Oliver Valerius, Sabine Thieme, Razieh Karimi, Antje K Heinrich, Florian Finkernagel, Kristina M Smith, Helge B Bode, Michael Freitag, Arthur F J Ram, Gerhard H Braus
Velvet domain protein VosA represses the zinc cluster transcription factor SclB regulatory network for Aspergillus nidulans asexual development, oxidative stress response and secondary metabolism. PLoS genetics 14 (7) (2018)
Lei Zhao, Marcel Kaiser, Helge B Bode
Rhabdopeptide/Xenortide-like Peptides from Xenorhabdus innexi with Terminal Amines Showing Potent Antiprotozoal Activity. Organic letters 20 (17) (2018)
Lei Zhao, Xiaofeng Cai, Marcel Kaiser, Helge B Bode
Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli. Journal of natural products 81 (10) (2018)
Yi-Ming Shi, Helge B Bode
Microbiology: A new language for small talk. Nature chemical biology 13 (5) (2018)
Nicholas J Tobias, Annabell Linck, Helge B Bode
Natural Product Diversification Mediated by Alternative Transcriptional Starting. Angewandte Chemie (International ed. in English) 57 (20) (2018)
Nicholas J Tobias, Hendrik Wolff, Bardya Djahanschiri, Florian Grundmann, Max Kronenwerth, Yi-Ming Shi, Svenja Simonyi, Peter Grün, David Shapiro-Ilan, Sacha J Pidot, Timothy P Stinear, Ingo Ebersberger, Helge B Bode
Natural product diversity associated with the nematode symbionts Photorhabdus and Xenorhabdus. Nature microbiology 2 (12) (2017)
Xiaofeng Cai, Victoria L Challinor, Lei Zhao, Daniela Reimer, Hélène Adihou, Peter Grün, Marcel Kaiser, Helge B Bode
Biosynthesis of the Antibiotic Nematophin and Its Elongated Derivatives in Entomopathogenic Bacteria. Organic letters 19 (4) (2017)
Xiaofeng Cai, Yi-Ming Shi, Nicole Pöhlmann, Ole Revermann, Isabel Bahner, Sacha J Pidot, Frank Wesche, Helmut Lackner, Claudia Büchel, Marcel Kaiser, Christian Richter, Harald Schwalbe, Timothy P Stinear, Axel Zeeck, Helge B Bode
Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66. Angewandte Chemie (International ed. in English) 56 (18) (2017)
Kenan A J Bozhüyük, Florian Fleischhacker, Annabell Linck, Frank Wesche, Andreas Tietze, Claus-Peter Niesert, Helge B Bode
De novo design and engineering of non-ribosomal peptide synthetases. Nature chemistry 10 (3) (2017)
Tim A Schöner, Sören Gassel, Ayako Osawa, Nicholas J Tobias, Yukari Okuno, Yui Sakakibara, Kazutoshi Shindo, Gerhard Sandmann, Helge B Bode
Aryl Polyenes, a Highly Abundant Class of Bacterial Natural Products, Are Functionally Related to Antioxidative Carotenoids. Chembiochem : a European journal of chemical biology 17 (3) (2016)
Xiaofeng Cai, Sarah Nowak, Frank Wesche, Iris Bischoff, Marcel Kaiser, Robert Fürst, Helge B Bode
Entomopathogenic bacteria use multiple mechanisms for bioactive peptide library design. Nature chemistry 9 (4) (2016)

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Helge B Bode