Leslie M Thompson (Leslie Thompson)

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 31

Top Topics

Binding Protein

Amyotrophic Lateral Sclerosis

Top Venues

Nature communications

Nature neuroscience

Scientific data

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Gianna M Fote, Vinay V Eapen, Ryan G Lim, Clinton Yu, Lisa Salazar, Nicolette R McClure, Jharrayne McKnight, Thai B Nguyen, Marie C Heath, Alice L Lau, Mark A Villamil, Ricardo Miramontes, Ian H Kratter, Steven Finkbeiner, Jack C Reidling, Joao A Paulo, Peter Kaiser, Lan Huang, David E Housman, Leslie M Thompson, Joan S Steffan
Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Gianna M Fote, Vinay V Eapen, Ryan G Lim, Clinton Yu, Lisa Salazar, Nicolette R McClure, Jharrayne McKnight, Thai B Nguyen, Marie C Heath, Alice L Lau, Mark A Villamil, Ricardo Miramontes, Ian H Kratter, Steven Finkbeiner, Jack C Reidling, Joao A Paulo, Peter Kaiser, Lan Huang, David E Housman, Leslie M Thompson, Joan S Steffan
Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Gianna M Fote, Vinay V Eapen, Ryan G Lim, Clinton Yu, Lisa Salazar, Nicolette R McClure, Jharrayne McKnight, Thai B Nguyen, Marie C Heath, Alice L Lau, Mark A Villamil, Ricardo Miramontes, Ian H Kratter, Steven Finkbeiner, Jack C Reidling, Joao A Paulo, Peter Kaiser, Lan Huang, David E Housman, Leslie M Thompson, Joan S Steffan
Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Gianna M Fote, Vinay V Eapen, Ryan G Lim, Clinton Yu, Lisa Salazar, Nicolette R McClure, Jharrayne McKnight, Thai B Nguyen, Marie C Heath, Alice L Lau, Mark A Villamil, Ricardo Miramontes, Ian H Kratter, Steven Finkbeiner, Jack C Reidling, Joao A Paulo, Peter Kaiser, Lan Huang, David E Housman, Leslie M Thompson, Joan S Steffan
Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America 121 (32) (2024)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Gong-Her Wu, Charlene Smith-Geater, Jesús G Galaz-Montoya, Yingli Gu, Sanket R Gupte, Ranen Aviner, Patrick G Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q Wang, Nicolette R Geller, Cathy Hou, Cristina Danita, Lydia-Marie Joubert, Michael F Schmid, Serena Yeung, Judith Frydman, William Mobley, Chengbiao Wu, Leslie M Thompson, Wah Chiu
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communications 14 (1) (2023)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Emily G Baxi, Terri Thompson, Jonathan Li, Julia A Kaye, Ryan G Lim, Jie Wu, Divya Ramamoorthy, Leandro Lima, Vineet Vaibhav, Andrea Matlock, Aaron Frank, Alyssa N Coyne, Barry Landin, Loren Ornelas, Elizabeth Mosmiller, Sara Thrower, S Michelle Farr, Lindsey Panther, Emilda Gomez, Erick Galvez, Daniel Perez, Imara Meepe, Susan Lei, Berhan Mandefro, Hannah Trost, Louis Pinedo, Maria G Banuelos, Chunyan Liu, Ruby Moran, Veronica Garcia, Michael Workman, Ritchie Ho, Stacia Wyman, Jennifer Roggenbuck, Matthew B Harms, Jennifer Stocksdale, Ricardo Miramontes, Keona Wang, Vidya Venkatraman, Ronald Holewenski, Niveda Sundararaman, Rakhi Pandey, Danica-Mae Manalo, Aneesh Donde, Nhan Huynh, Miriam Adam, Brook T Wassie, Edward Vertudes, Naufa Amirani, Krishna Raja, Reuben Thomas, Lindsey Hayes, Alex Lenail, Aianna Cerezo, Sarah Luppino, Alanna Farrar, Lindsay Pothier, Carolyn Prina, Todd Morgan, Arish Jamil, Sarah Heintzman, Jennifer Jockel-Balsarotti, Elizabeth Karanja, Jesse Markway, Molly McCallum, Ben Joslin, Deniz Alibazoglu, Stephen J Kolb, Senda Ajroud-Driss, Robert H Baloh, Daragh Heitzman, Tim Miller, Jonathan D Glass, Natasha Leanna Patel-Murray, Hong Yu, Ervin Sinani, Prasha Vigneswaran, Alexander V Sherman, Omar Ahmad, Promit Roy, Jay C Beavers, Steven Zeiler, John W Krakauer, Carla Agurto, Guillermo A Cecchi, Mary Bellard, Yogindra Raghav, Karen Sachs, Tobias Ehrenberger, Elizabeth Bruce, Merit E Cudkowicz, Nicholas J Maragakis, Raquel Norel, Jennifer E Van Eyk, Steven Finkbeiner, James Berry, Dhruv Sareen, Leslie M Thompson, Ernest Fraenkel, Clive N Svendsen, Jeffrey D Rothstein
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nature neuroscience 25 (2) (2022)
Kathryn H Morelli, Qian Wu, Maya L Gosztyla, Hongshuai Liu, Minmin Yao, Chuangchuang Zhang, Jia-Xu Chen, Ryan J Marina, Kari Lee, Krysten L Jones, Megan Y Huang, Allison Li, Charlene Smith-Geater, Leslie M Thompson, Wenzhen Duan, Gene W Yeo
An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models. Nature neuroscience 26 (1) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)