Linda Z Penn (Linda Penn)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 16

Top Venues

Cancer research

Prostate cancer and prostatic diseases

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa

Nature reviews. Cancer

University Health Network

University of Toronto, The Hospital for Sick Children, Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Health Network

Canada

Director :: Office of Research Trainees

University of Toronto

Canada

Full Professor :: Medical Biophysics

Princess Margaret Cancer Centre

Canada

Senior Scientist :: Research

Princess Margaret Cancer Centre

Canada

Director :: Genomics Centre

University Health Network

Canada

Executive Committee :: Princess Margaret Cancer Research

University Health Network

Canada

Co-Director :: Microarray Centre

Princess Margaret Cancer Centre

Canada

Division Head :: Cancer Genomics and Proteomics

University of Toronto

Canada

Associate Professor :: Medical Biophysics

Hospital for Sick Children

Canada

Senior Research Scientist :: Microbiology

University of Toronto

Canada

Assistant Professor :: Microbiology

Hospital for Sick Children

Canada

Cross-Appointment :: Division of Immunology and Cancer Research

Hospital for Sick Children

Canada

Scientist :: Microbiology

Imperial Cancer Research Fund

United Kingdom

Post-Doctoral Fellow :: Growth Control and Development Laboratory

Education History

University of Toronto, The Hospital for Sick Children, Research Institute

Canada

PHD :: Microbiology

University of Guelph

Canada

BSC :: Microbiology

Publications

Peter Lin, Corey Lourenco, Jennifer Cruickshank, Luis Palomero, Jenna E van Leeuwen, Amy H Y Tong, Katherine Chan, Samah El Ghamrasni, Miguel Angel Pujana, David W Cescon, Jason Moffat, Linda Z Penn
Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality. Cancer research (2023)
Emma L Craig, Konrad H Stopsack, Emma Evergren, Linda Z Penn, Stephen J Freedland, Robert J Hamilton, Emma H Allott
Statins and prostate cancer-hype or hope? The epidemiological perspective. Prostate cancer and prostatic diseases 25 (4) (2022)
Yong Wei, Cornelia Redel, Alexandra Ahlner, Alexander Lemak, Isak Johansson-Åkhe, Scott Houliston, Tristan M G Kenney, Aaliya Tamachi, Vivian Morad, Shili Duan, David William Andrews, Björn Wallner, Maria Sunnerhagen, Cheryl H Arrowsmith, Linda Z Penn
The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. Nucleic acids research 50 (6) (2022)
Jenna E van Leeuwen, Wail Ba-Alawi, Emily Branchard, Jennifer Cruickshank, Wiebke Schormann, Joseph Longo, Jennifer Silvester, Peter L Gross, David William Andrews, David W Cescon, Benjamin Haibe-Kains, Linda Z Penn, Deena M A Gendoo
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins. Nature communications 13 (1) (2022)
Joseph Longo, Stephen J Freedland, Linda Z Penn, Robert J Hamilton
Statins and prostate cancer-hype or hope? The biological perspective. Prostate cancer and prostatic diseases 25 (4) (2022)
Wail Ba-Alawi, Sisira Kadambat Nair, Bo Li, Anthony Mammoliti, Petr Smirnov, Arvind Singh Mer, Linda Z Penn, Benjamin Haibe-Kains
Bimodal Gene Expression in Patients with Cancer Provides Interpretable Biomarkers for Drug Sensitivity. Cancer research 82 (13) (2022)
Philipp Mergenthaler, Santosh Hariharan, James M Pemberton, Corey Lourenco, Linda Z Penn, David William Andrews
Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning. PLoS computational biology 17 (2) (2021)
Corey Lourenco, Diana Resetca, Cornelia Redel, Peter Lin, Alannah S MacDonald, Roberto Ciaccio, Tristan M G Kenney, Yong Wei, David W Andrews, Maria Sunnerhagen, Cheryl H Arrowsmith, Brian Raught, Linda Z Penn
MYC protein interactors in gene transcription and cancer. Nature reviews. Cancer 21 (9) (2021)
Rosemary Yu, Joseph Longo, Jenna E van Leeuwen, Cunjie Zhang, Emily Branchard, Mohamad Elbaz, David W Cescon, Richard R Drake, James W Dennis, Linda Z Penn
Mevalonate Pathway Inhibition Slows Breast Cancer Metastasis via Reduced N-glycosylation Abundance and Branching. Cancer research 81 (10) (2021)
Adam J Wolpaw, Richard Bayliss, Gabriele Büchel, Chi Van Dang, Martin Eilers, W Clay Gustafson, Gwenn H Hansen, Natalia Jura, Stefan Knapp, Mark A Lemmon, David Levens, John M Maris, Ronen Marmorstein, Steven J Metallo, Julie R Park, Linda Z Penn, Michael Rape, Martine F Roussel, Kevan M Shokat, William P Tansey, Kliment A Verba, Seychelle M Vos, William A Weiss, Elmar Wolf, Yael P Mosse
Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers. Cancer research 81 (7) (2021)
Joseph Longo, Jenna E van Leeuwen, Mohamad Elbaz, Emily Branchard, Linda Z Penn
Statins as Anticancer Agents in the Era of Precision Medicine. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (22) (2020)
Joseph Longo, Aleksandra A Pandyra, Paweł Stachura, Mark D Minden, Aaron D Schimmer, Linda Z Penn
Cyclic AMP-hydrolyzing phosphodiesterase inhibitors potentiate statin-induced cancer cell death. Molecular oncology 14 (10) (2020)
Joseph Longo, Petr Smirnov, Zhihua Li, Emily Branchard, Jenna E van Leeuwen, Jonathan D Licht, Benjamin Haibe-Kains, David William Andrews, Jonathan J Keats, Trevor J Pugh, Suzanne Trudel, Linda Z Penn
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma. Leukemia 35 (3) (2020)
K Ashley Hickman, Santosh Hariharan, Jason De Melo, Jarkko Ylanko, Lindsay C Lustig, Linda Z Penn, David William Andrews
Image-Based Analysis of Protein Stability. Cytometry. Part A : the journal of the International Society for Analytical Cytology 97 (4) (2019)
Corey Lourenco, Manpreet Kalkat, Kathleen E Houlahan, Jason De Melo, Joseph Longo, Susan J Done, Paul C Boutros, Linda Z Penn
Modelling the MYC-driven normal-to-tumour switch in breast cancer. Disease models & mechanisms 12 (7) (2019)
Kirsty K Hall, Joelle Tambekou, Linda Z Penn, Alioune Camara, Naby M Balde, Eugene Sobngwi
Association between depression, glycaemic control and the prevalence of diabetic retinopathy in a diabetic population in Cameroon. The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa 23 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Linda Z Penn (Linda Penn)