David William Andrews (David W Andrews)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 26

Top Venues

eLife

The Biochemical journal

EMBO reports

The EMBO journal

Sunnybrook Research Institute

University of Toronto (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Sunnybrook Research Institute

Canada

Director and Senior Scientist, Biological Sciences :: Odette Cancer Program

Education History

University of Toronto

Canada

PHD :: Medical Biophysics

University of Ottawa

Canada

BSC :: Biochemistry

Publications

Dang Nguyen, Elizabeth Osterlund, Justin Kale, David William Andrews
The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death. The Biochemical journal 481 (14) (2024)
Tobias B Beigl, Alexander Paul, Thomas P Fellmeth, Dang Nguyen, Lynn Barber, Sandra Weller, Benjamin Schäfer, Bernhard F Gillissen, Walter E Aulitzky, Hans-Georg Kopp, Markus Rehm, David William Andrews, Kristyna Pluhackova, Frank Essmann
BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains. EMBO reports (2024)
Dang Nguyen, Elizabeth Osterlund, Justin Kale, David William Andrews
The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death. The Biochemical journal 481 (14) (2024)
Dang Nguyen, Elizabeth Osterlund, Justin Kale, David William Andrews
The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death. The Biochemical journal 481 (14) (2024)
James M Pemberton, Dang Nguyen, Elizabeth J Osterlund, Wiebke Schormann, Justin P Pogmore, Nehad Hirmiz, Brian Leber, David William Andrews
The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes. eLife 12 (2023)
Yong Wei, Cornelia Redel, Alexandra Ahlner, Alexander Lemak, Isak Johansson-Åkhe, Scott Houliston, Tristan M G Kenney, Aaliya Tamachi, Vivian Morad, Shili Duan, David William Andrews, Björn Wallner, Maria Sunnerhagen, Cheryl H Arrowsmith, Linda Z Penn
The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. Nucleic acids research 50 (6) (2022)
Jenna E van Leeuwen, Wail Ba-Alawi, Emily Branchard, Jennifer Cruickshank, Wiebke Schormann, Joseph Longo, Jennifer Silvester, Peter L Gross, David William Andrews, David W Cescon, Benjamin Haibe-Kains, Linda Z Penn, Deena M A Gendoo
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins. Nature communications 13 (1) (2022)
Elizabeth J Osterlund, Nehad Hirmiz, James M Pemberton, Adrien Nougarède, Qian Liu, Brian Leber, Qiyin Fang, David William Andrews
Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells. Science advances 8 (16) (2022)
Philipp Mergenthaler, Santosh Hariharan, James M Pemberton, Corey Lourenco, Linda Z Penn, David William Andrews
Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning. PLoS computational biology 17 (2) (2021)
David William Andrews, Kevin D Judy, Charles B Scott, Samantha Garcia, Larry A Harshyne, Lawrence C Kenyon, Kiran Talekar, Adam E Flanders, Kofi-Buaku Atsina, Lyndon Kim, Nina Martinez, Wenyin Shi, Maria Werner-Wasik, Haisong Liu, Mikhail Prosniak, Mark Curtis, Rhonda Kean, Donald Y Ye, Emily Bongiorno, Sami Sauma, Mark A Exley, Kara Pigott, D Craig Hooper
Phase Ib Clinical Trial of IGV-001 for Patients with Newly Diagnosed Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (7) (2021)
Justin P Pogmore, David Uehling, David William Andrews
Pharmacological Targeting of Executioner Proteins: Controlling Life and Death. Journal of medicinal chemistry 64 (9) (2021)
Fujiao Lv, Fei Qi, Zhi Zhang, Maorong Wen, Justin Kale, Alessandro Piai, Lingyu Du, Shuqing Wang, Liujuan Zhou, Yaqing Yang, Bin Wu, Zhijun Liu, Juan Del Rosario, Justin Pogmore, James J Chou, David William Andrews, Jialing Lin, Bo Ouyang
An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial␣membrane. The EMBO journal 40 (14) (2021)
James M Pemberton, Justin P Pogmore, David William Andrews
Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins. Cell death and differentiation 28 (1) (2020)
Tamara Vervloessem, Binu K Sasi, Elena Xerxa, Spyridoula Karamanou, Justin Kale, Rita M La Rovere, Supriya Chakraborty, Flore Sneyers, Meike Vogler, Anastassios Economou, Luca Laurenti, David William Andrews, Dimitar G Efremov, Geert Bultynck
BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models. Cell death & disease 11 (9) (2020)
Xiaoke Chi, Dang Nguyen, James M Pemberton, Elizabeth J Osterlund, Qian Liu, Hetal Brahmbhatt, Zhi Zhang, Jialing Lin, Brian Leber, David William Andrews
The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells. eLife 9 (2020)
Joseph Longo, Petr Smirnov, Zhihua Li, Emily Branchard, Jenna E van Leeuwen, Jonathan D Licht, Benjamin Haibe-Kains, David William Andrews, Jonathan J Keats, Trevor J Pugh, Suzanne Trudel, Linda Z Penn
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma. Leukemia 35 (3) (2020)
Chen Farhy, Santosh Hariharan, Jarkko Ylanko, Luis Orozco, Fu-Yue Zeng, Ian Pass, Fernando Ugarte, E Camilla Forsberg, Chun-Teng Huang, David William Andrews, Alexey V Terskikh
Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape. eLife 8 (2019)
Glauber Costa Brito, Wiebke Schormann, Satinder K Gidda, Robert T Mullen, David William Andrews
Genome-wide analysis of Homo sapiens, Arabidopsis thaliana, and Saccharomyces cerevisiae reveals novel attributes of tail-anchored membrane proteins. BMC genomics 20 (1) (2019)
Brian Leber, Justin Kale, David William Andrews
Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove. Cancer discovery 8 (12) (2019)
Qian Liu, Elizabeth J Osterlund, Xiaoke Chi, Justin Pogmore, Brian Leber, David William Andrews
Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2. eLife 8 (2019)
K Ashley Hickman, Santosh Hariharan, Jason De Melo, Jarkko Ylanko, Lindsay C Lustig, Linda Z Penn, David William Andrews
Image-Based Analysis of Protein Stability. Cytometry. Part A : the journal of the International Society for Analytical Cytology 97 (4) (2019)
Laura Canty, Santosh Hariharan, Qian Liu, Steven A Haney, David William Andrews
Peak emission wavelength and fluorescence lifetime are coupled in far-red, GFP-like fluorescent proteins. PloS one 13 (11) (2018)
Justin Kale, Meryem Ozlem Kutuk, Glauber Costa Brito, Tallulah S Andrews, Brian Leber, Anthony G Letai, David William Andrews
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. EMBO reports 19 (9) (2018)
Christianne Hoey, Jessica Ray, Jouhyun Jeon, Xiaoyong Huang, Samira Taeb, Jarkko Ylanko, David William Andrews, Paul C Boutros, Stanley K Liu
miRNA-106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation. Molecular oncology 12 (8) (2018)
Satinder K Gidda, Sunjung Park, Michal Pyc, Olga Yurchenko, Yingqi Cai, Peng Wu, David William Andrews, Kent D Chapman, John M Dyer, Robert T Mullen
Lipid Droplet-Associated Proteins (LDAPs) Are Required for the Dynamic Regulation of Neutral Lipid Compartmentation in Plant Cells. Plant physiology 170 (4) (2016)
Sina Oppermann, Jarkko Ylanko, Yonghong Shi, Santosh Hariharan, Christopher C Oakes, Patrick M Brauer, Juan C Zúñiga-Pflücker, Brian Leber, David E Spaner, David William Andrews
High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells. Blood 128 (7) (2016)

David William Andrews.css-eqlu8i{font-size:small;padding-left:4px;} (David W Andrews)

Publication Activity (10 Years)

Top Topics

Top Venues

David William Andrews (David W Andrews)