Jonathan D Licht

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 26

Top Venues

Blood

Cancer discovery

Nature chemical biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Daphne Dupéré-Richer, Alberto Riva, Sayantan Maji, Benjamin G Barwick, Heidi Casellas Román, Amin Sobh, Gabrielle Quickstad, Jianping Li, Umasankar De, Crissandra Piper, Marta Kulis, Teresa Ezponda, José Ignacio Martin-Subero, Giovanni Tonon, Weizhou Zhang, Constantine S Mitsiades, Lawrence H Boise, Richard L Bennett, Jonathan D Licht
KDM6A Regulates Immune Response Genes in Multiple Myeloma. bioRxiv : the preprint server for biology (2024)
Amin Sobh, Elena Encinas, Alisha M Patel, Greeshma Surapaneni, Emilie Bonilla, Charlotte Kaestner, Janai Poullard, Monica Clerio, Karthik Vasan, Tzipporah Freeman, Dong-Wen Lv, Daphné Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Daohong Zhou, Lawrence H Boise, Constantine S Mitsiades, Baek Kim, Richard L Bennett, Navdeep S Chandel, Jonathan D Licht
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome. Blood 144 (3) (2024)
Amin Sobh, Elena Encinas, Alisha M Patel, Greeshma Surapaneni, Emilie Bonilla, Charlotte Kaestner, Janai Poullard, Monica Clerio, Karthik Vasan, Tzipporah Freeman, Dong-Wen Lv, Daphné Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Daohong Zhou, Lawrence H Boise, Constantine S Mitsiades, Baek Kim, Richard L Bennett, Navdeep S Chandel, Jonathan D Licht
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome. Blood 144 (3) (2024)
Daphne Dupéré-Richer, Alberto Riva, Sayantan Maji, Benjamin G Barwick, Heidi Casellas Román, Amin Sobh, Gabrielle Quickstad, Jianping Li, Umasankar De, Crissandra Piper, Marta Kulis, Teresa Ezponda, José Ignacio Martin-Subero, Giovanni Tonon, Weizhou Zhang, Constantine S Mitsiades, Lawrence H Boise, Richard L Bennett, Jonathan D Licht
KDM6A Regulates Immune Response Genes in Multiple Myeloma. bioRxiv : the preprint server for biology (2024)
Daphne Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Sayantan Maji, Heidi Casellas Roman, Jianping Li, Umasankar De, Amin Sobh, Gabrielle Quickstad, Crissandra Piper, Marta Kulis, Teresa Ezponda, José-Ignacio Ignacio Martín-Subero, Giovanni Tonon, Weizhou Zhang, Constantine S Mitsiades, Lawrence H Boise, Richard L Bennett, Jonathan D Licht
KDM6A Regulates Immune Response Genes in Multiple Myeloma. Blood (2024)
Amin Sobh, Elena Encinas, Alisha M Patel, Greeshma Surapaneni, Emilie Bonilla, Charlotte Leonie Kaestner, Janai Poullard, Monica Clerio, Karthik Vasan, Tzipporah Freeman, Dong-Wen Lv, Daphné Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Daohong Zhou, Lawrence H Boise, Constantine S Mitsiades, Baek Kim, Richard L Bennett, Navdeep S Chandel, Jonathan D Licht
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome. Blood (2024)
Daphne Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Sayantan Maji, Heidi Casellas Roman, Jianping Li, Umasankar De, Amin Sobh, Gabrielle Quickstad, Crissandra Piper, Marta Kulis, Teresa Ezponda, José-Ignacio Ignacio Martín-Subero, Giovanni Tonon, Weizhou Zhang, Constantine S Mitsiades, Lawrence H Boise, Richard L Bennett, Jonathan D Licht
KDM6A Regulates Immune Response Genes in Multiple Myeloma. Blood (2024)
David Y Nie, John R Tabor, Jianping Li, Maria Kutera, Jonathan St-Germain, Ronan P Hanley, Esther Wolf, Ethan Paulakonis, Tristan M G Kenney, Shili Duan, Suman Shrestha, Dominic D G Owens, Matthew E R Maitland, Ailing Pon, Magdalena Szewczyk, Anthony Joseph Lamberto, Michael Menes, Fengling Li, Linda Z Penn, Dalia Barsyte-Lovejoy, Nicholas G Brown, Anthony M Barsotti, Andrew W Stamford, Jon L Collins, Derek J Wilson, Brian Raught, Jonathan D Licht, Lindsey I James, Cheryl H Arrowsmith
Recruitment of FBXO22 for targeted degradation of NSD2. Nature chemical biology (2024)
David Y Nie, John R Tabor, Jianping Li, Maria Kutera, Jonathan St-Germain, Ronan P Hanley, Esther Wolf, Ethan Paulakonis, Tristan M G Kenney, Shili Duan, Suman Shrestha, Dominic D G Owens, Matthew E R Maitland, Ailing Pon, Magdalena Szewczyk, Anthony Joseph Lamberto, Michael Menes, Fengling Li, Linda Z Penn, Dalia Barsyte-Lovejoy, Nicholas G Brown, Anthony M Barsotti, Andrew W Stamford, Jon L Collins, Derek J Wilson, Brian Raught, Jonathan D Licht, Lindsey I James, Cheryl H Arrowsmith
Recruitment of FBXO22 for targeted degradation of NSD2. Nature chemical biology (2024)
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick, Vilas A Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M Meyers, Jordan G Bryan, Neekesh V Dharia, Paul J Hengeveld, Johanna B Brüggenthies, Huihui Tang, Andrew J Aguirre, Quinlan L Sievers, Benjamin L Ebert, Brian J Glassner, Christopher J Ott, James E Bradner, Nicholas P Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J Keats, Richard W J Groen, Nathanael S Gray, Aedin C Culhane, James M McFarland, Joshua M Dempster, Jonathan D Licht, Lawrence H Boise, William C Hahn, Francisca Vazquez, Aviad Tsherniak, Constantine S Mitsiades
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature cancer 4 (5) (2023)
Michael F Emmons, Richard L Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Chao Zhang, Robert J B Macaulay, Daphne Dupéré-Richér, Bin Fang, Edward Seto, John M Koomen, Jiannong Li, Yian Ann Chen, Peter A Forsyth, Jonathan D Licht, Keiran S M Smalley
HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. Nature communications 14 (1) (2023)
Christopher J Kaler, James J Dollar, Anthony M Cruz, Jeffim N Kuznetsoff, Margaret I Sanchez, Christina L Decatur, Jonathan D Licht, Keiran S M Smalley, Zelia M Correa, Stefan Kurtenbach, J William Harbour
BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas. Cancers 14 (15) (2022)
Sathya Neelature Sriramareddy, Fernanda Faião-Flores, Michael F Emmons, Biswarup Saha, Srikumar P Chellappan, Clayton Wyatt, Inna Smalley, Jonathan D Licht, Michael A Durante, J William Harbour, Keiran S M Smalley
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma. Cancer gene therapy (2022)
Samuel E J Preston, Audrey Emond, Filippa Pettersson, Daphné Dupéré-Richer, Madelyn Jean Abraham, Alberto Riva, Mena Kinal, Ryan N Rys, Nathalie A Johnson, Koren K Mann, Sonia V Del Rincón, Jonathan D Licht, Wilson H Miller
Acquired Resistance to EZH2 Inhibitor GSK343 Promotes the Differentiation of Human DLBCL Cell Lines toward an ABC-Like Phenotype. Molecular cancer therapeutics 21 (4) (2022)
Kartika Venugopal, Yang Feng, Pawel Nowialis, Huanzhou Xu, Daniil E Shabashvili, Cassandra M Berntsen, Prabhjot Kaur, Kathryn I Krajcik, Christina Taragjini, Zachary Zaroogian, Heidi L Casellas Román, Luisa M Posada, Chamara Gunaratne, Jianping Li, Daphné Dupéré-Richer, Richard L Bennett, Santhi Pondugula, Alberto Riva, Christopher R Cogle, Rene Opavsky, Brian K Law, Sumita Bhaduri-McIntosh, Stefan Kubicek, Philipp B Staber, Jonathan D Licht, Jonathan E Bird, Olga A Guryanova
DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Jonathan D Licht
Histone H3 G34 Tail Mutations in Cancer: Actions in Cis and Trans to Alter Chromatin and Gene Expression. Cancer discovery 10 (12) (2021)
Jianping Li, Julia Hlavka-Zhang, Jonathan H Shrimp, Crissandra Piper, Daphne Dupere-Richer, Jacob S Roth, Duohui Jing, Heidi L Casellas Roman, Catalina Troche, Alok Swaroop, Marta Kulis, Jon A Oyer, Christine M Will, Min Shen, Alberto Riva, Richard L Bennett, Adolfo A Ferrando, Matthew D Hall, Richard B Lock, Jonathan D Licht
PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia. Cancer discovery (2021)
Nevin Yusufova, Andreas Kloetgen, Matt Teater, Adewola Osunsade, Jeannie M Camarillo, Christopher R Chin, Ashley S Doane, Bryan J Venters, Stephanie Portillo-Ledesma, Joseph Conway, Jude M Phillip, Olivier Elemento, David W Scott, Wendy Béguelin, Jonathan D Licht, Michael P Snyder, Louis M Staudt, Arthur I Skoultchi, Michael-Christopher Keogh, Effie Apostolou, Christopher E Mason, Marcin Imielinski, Tamar Schlick, Yael David, Aristotelis Tsirigos, C David Allis, Alexey A Soshnev, Ethel Cesarman, Ari M Melnick
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture. Nature 589 (7841) (2020)
Yue Sheng, Chunjie Yu, Yin Liu, Chao Hu, Rui Ma, Xinyan Lu, Peng Ji, Jianjun Chen, Benjamin E Mizukawa, Yong Huang, Jonathan D Licht, Zhijian Qian
FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML. Nature communications 11 (1) (2020)
Joseph Longo, Petr Smirnov, Zhihua Li, Emily Branchard, Jenna E van Leeuwen, Jonathan D Licht, Benjamin Haibe-Kains, David William Andrews, Jonathan J Keats, Trevor J Pugh, Suzanne Trudel, Linda Z Penn
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma. Leukemia 35 (3) (2020)
Fernanda Faião-Flores, Michael F Emmons, Michael A Durante, Fumi Kinose, Biswarup Saha, Bin Fang, John M Koomen, Srikumar P Chellappan, Silvya Stuchi Maria-Engler, Uwe Rix, Jonathan D Licht, J William Harbour, Keiran S M Smalley
HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (18) (2019)
Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jürgen Christian Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian A Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, Keiran S M Smalley
HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy. Cancer research 79 (11) (2019)
Richard L Bennett, Aditya Bele, Eliza C Small, Christine M Will, Behnam Nabet, Jon A Oyer, Xiaoxiao Huang, Rajarshi P Ghosh, Adrian T Grzybowski, Tao Yu, Qiao Zhang, Alberto Riva, Tanmay P Lele, George C Schatz, Neil L Kelleher, Alexander J Ruthenburg, Jan Liphardt, Jonathan D Licht
A Mutation in Histone H2B Represents a New Class of Oncogenic Driver. Cancer discovery 9 (10) (2019)
Alok Swaroop, Jon A Oyer, Christine M Will, Xiaoxiao Huang, Wenbo Yu, Catalina Troche, Marinka Bulic, Benjamin H Durham, Qiang Jeremy Wen, John D Crispino, Alexander D MacKerell, Richard L Bennett, Michael P Snyder, Jonathan D Licht
An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia. Oncogene 38 (5) (2018)
Jonathan D Licht
SETD2: a complex role in blood malignancy. Blood 130 (24) (2018)
Kelly M Arcipowski, Marinka Bulic, Sandeep Gurbuxani, Jonathan D Licht
Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis. PloS one 11 (9) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jonathan D Licht