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Andrea Sottoriva

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 29

Top Venues

Nature genetics

Nature communications

Nature

Science (New York, N.Y.)

The Institute of Cancer Research

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Institute of Cancer Research Nov 21o 2017

United Kingdom

Tenured Group Leader :: Molecular Pathology

Publications

Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics (2023)
Bingjie Chen, Daniele Ramazzotti, Timon Heide, Inmaculada Spiteri, Javier Fernández-Mateos, Chela James, Luca Magnani, Trevor A Graham, Andrea Sottoriva
Contribution of pks + E. coli mutations to colorectal carcinogenesis. Nature communications 14 (1) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Giovanni Ciriello, Luca Magnani, Sarah J Aitken, Leila Akkari, Sam Behjati, Douglas Hanahan, Dan A Landau, Núria López-Bigas, Darío G Lupiáñez, Jean-Christophe Marine, Ana Martin-Villalba, Gioacchino Natoli, Anna C Obenauf, Elisa Oricchio, Paola Scaffidi, Andrea Sottoriva, Alexander Swarbrick, Giovanni Tonon, Sakari Vanharanta, Johannes Zuber
Cancer Evolution: A Multifaceted Affair. Cancer discovery (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Luis Zapata, Giulio Caravagna, Marc J Williams, Eszter Lakatos, Khalid AbdulJabbar, Benjamin Werner, Diego Chowell, Chela James, Lucie Gourmet, Salvatore Milite, Ahmet Acar, Nadeem Riaz, Timothy A Chan, Trevor A Graham, Andrea Sottoriva
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors. Nature genetics 55 (3) (2023)
Timon Heide, Jacob Househam, George D Cresswell, Inmaculada Spiteri, Claire Lynn, Maximilian Mossner, Chris Kimberley, Javier Fernandez-Mateos, Bingjie Chen, Luis Zapata, Chela James, Iros Barozzi, Ketevan Chkhaidze, Daniel Nichol, Vinaya Gunasri, Alison May Berner, Melissa Schmidt, Eszter Lakatos, Ann-Marie C Baker, Helena Costa, Miriam Mitchinson, Rocco Giovanni Piazza, Marnix Jansen, Giulio Caravagna, Daniele Ramazzotti, Darryl Shibata, John A Bridgewater, Manuel Rodriguez, Luca Magnani, Trevor A Graham, Andrea Sottoriva
The co-evolution of the genome and epigenome in colorectal cancer. Nature 611 (7937) (2022)
Jacob Househam, Timon Heide, George D Cresswell, Inmaculada Spiteri, Chris Kimberley, Luis Zapata, Claire Lynn, Chela James, Maximilian Mossner, Javier Fernandez-Mateos, Alessandro Vinceti, Ann-Marie C Baker, Calum Gabbutt, Alison Berner, Melissa Schmidt, Bingjie Chen, Eszter Lakatos, Vinaya Gunasri, Daniel Nichol, Helena Costa, Miriam Mitchinson, Daniele Ramazzotti, Benjamin Werner, Francesco Iorio, Marnix Jansen, Giulio Caravagna, Christopher P Barnes, Darryl Shibata, John A Bridgewater, Manuel Rodriguez, Luca Magnani, Andrea Sottoriva, Trevor A Graham
Phenotypic plasticity and genetic control in colorectal cancer evolution. Nature 611 (7937) (2022)
Chandler D Gatenbee, Ann-Marie C Baker, Ryan O Schenck, Maximilian A R Strobl, Jeffrey West, Margarida P Neves, Sara Yakub Hasan, Eszter Lakatos, Pierre Martinez, William C H Cross, Marnix Jansen, Manuel Rodriguez, Christopher J Whelan, Andrea Sottoriva, Simon Leedham, Mark Robertson-Tessi, Trevor A Graham, Alexander A R A Anderson
Immunosuppressive niche engineering at the onset of human colorectal cancer. Nature communications 13 (1) (2022)
Yannik Bollen, Ellen Stelloo, Petra van Leenen, Myrna van den Bos, Bas Ponsioen, Bingxin Lu, Markus J van Roosmalen, Ana C F Bolhaqueiro, Christopher Kimberley, Maximilian Mossner, William C H Cross, Nicolle J M Besselink, Bastiaan R Van der Roest, Sander Boymans, Koen C Oost, Sippe G de Vries, Holger Rehmann, Edwin Cuppen, Susanne M A Lens, Geert J P L Kops, Wigard P Kloosterman, Leon W M M Terstappen, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham, Hugo J G Snippert
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns. Nature genetics 53 (8) (2021)
Barbara Lupo, Francesco Sassi, Marika Pinnelli, Francesco Galimi, Eugenia R Zanella, Valentina Vurchio, Giorgia Migliardi, Paolo Armando Gagliardi, Alberto Puliafito, Daria Manganaro, Paolo Luraghi, Michael Kragh, Mikkel W Pedersen, Ivan D Horak, Carla Boccaccio, Enzo Medico, Luca Primo, Daniel Nichol, Inmaculada Spiteri, Timon Heide, Alexandra Vatsiou, Trevor A Graham, Elena Élez, Guillem Argiles, Paolo G Nuciforo, Andrea Sottoriva, Rodrigo Dienstmann, Diego Pasini, Elena Grassi, Claudio Isella, Andrea Bertotti, Livio Trusolino
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype. Science translational medicine 12 (555) (2021)
George D Cresswell, Daniel Nichol, Inmaculada Spiteri, Haider Tari, Luis Zapata, Timon Heide, Carlo C Maley, Luca Magnani, Gaia Schiavon, Alan Ashworth, Peter Barry, Andrea Sottoriva
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking. Nature communications 11 (1) (2020)
Marc J Williams, Luis Zapata, Benjamin Werner, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham
Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios. eLife 9 (2020)
Ahmet Acar, Daniel Nichol, Javier Fernandez-Mateos, George D Cresswell, Iros Barozzi, Sung Pil Hong, Nicholas Trahearn, Inmaculada Spiteri, Mark Stubbs, Rosemary Burke, Adam Stewart, Giulio Caravagna, Benjamin Werner, Georgios Vlachogiannis, Carlo C Maley, Luca Magnani, Nicola Valeri, Udai Banerji, Andrea Sottoriva
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer. Nature communications 11 (1) (2020)
Eszter Lakatos, Marc J Williams, Ryan O Schenck, William C H Cross, Jacob Househam, Luis Zapata, Benjamin Werner, Chandler Gatenbee, Mark Robertson-Tessi, Christopher P Barnes, Alexander A R A Anderson, Andrea Sottoriva, Trevor A Graham
Evolutionary dynamics of neoantigens in growing tumors. Nature genetics 52 (10) (2020)
Benjamin Werner, Jack Case, Marc J Williams, Ketevan Chkhaidze, Daniel Temko, Javier Fernández-Mateos, George D Cresswell, Daniel Nichol, William Cross, Inmaculada Spiteri, Weini Huang, Ian P M Tomlinson, Christopher P Barnes, Trevor A Graham, Andrea Sottoriva
Measuring single cell divisions in human tissues from multi-region sequencing data. Nature communications 11 (1) (2020)
Giulio Caravagna, Timon Heide, Marc J Williams, Luis Zapata, Daniel Nichol, Ketevan Chkhaidze, William Cross, George D Cresswell, Benjamin Werner, Ahmet Acar, Louis Chesler, Christopher P Barnes, Guido Sanguinetti, Trevor A Graham, Andrea Sottoriva
Subclonal reconstruction of tumors by using machine learning and population genetics. Nature genetics 52 (9) (2020)
Benjamin Werner, Marc J Williams, Christopher P Barnes, Trevor A Graham, Andrea Sottoriva
Reply to 'Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution'. Nature genetics 50 (12) (2019)
Samra Turajlic, Andrea Sottoriva, Trevor A Graham, Charles Swanton
Resolving genetic heterogeneity in cancer. Nature reviews. Genetics 20 (7) (2019)
Ketevan Chkhaidze, Timon Heide, Benjamin Werner, Marc J Williams, Weini Huang, Giulio Caravagna, Trevor A Graham, Andrea Sottoriva
Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data. PLoS computational biology 15 (7) (2019)
Marc J Williams, Benjamin Werner, Timon Heide, Christopher P Barnes, Trevor A Graham, Andrea Sottoriva
Reply to 'Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data'. Nature genetics 50 (12) (2019)
Marc J Williams, Benjamin Werner, Chris P Barnes, Trevor A Graham, Andrea Sottoriva
Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures. Nature genetics 49 (9) (2019)
Andreas Heindl, Adnan Mujahid Khan, Daniel Nava Rodrigues, Katherine Eason, Anguraj Sadanandam, Cecilia Orbegoso, Marco Punta, Andrea Sottoriva, Stefano Lise, Susana Banerjee, Yinyin Yuan
Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity. Nature communications 9 (1) (2018)
Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou, Yann Jamin, Javier Fernández-Mateos, Khurum Khan, Andrea Lampis, Katherine Eason, Ian Huntingford, Rosemary Burke, Mihaela Rata, Dow-Mu Koh, Nina Tunariu, David Collins, Sanna Hulkki-Wilson, Chanthirika Ragulan, Inmaculada Spiteri, Sing Yu Moorcraft, Ian Chau, Sheela Rao, David Watkins, Nicos Fotiadis, Maria Antonietta Bali, Mahnaz Darvish Damavandi, Hazel Lote, Zakaria Eltahir, Elizabeth C Smyth, Ruwaida Begum, Paul Andrew Clarke, Jens C Hahne, Mitchell Dowsett, Johann de Bono, Paul Workman, Anguraj Sadanandam, Angelo Paolo Dei Tos, Owen J Sansom, Suzanne Eccles, Naureen Starling, Chiara Braconi, Andrea Sottoriva, Simon P Robinson, David Cunningham, Nicola Valeri
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science (New York, N.Y.) 359 (6378) (2018)
William Cross, Michal Kovac, Ville Mustonen, Daniel Temko, Hayley Davis, Ann-Marie Baker, Sujata Biswas, Roland Arnold, Laura Chegwidden, Chandler Gatenbee, Alexander A R A Anderson, Viktor Hendrik Koelzer, Pierre Martinez, Xiaowei Jiang, Enric Domingo, Dan J Woodcock, Yun Feng, Monika Kovacova, Tim Maughan, null null, Marnix Jansen, Manuel Rodriguez-Justo, Shazad Ashraf, Richard Guy, Christopher Cunningham, James E East, David C Wedge, Lai Mun Wang, Claire Palles, Karl Heinimann, Andrea Sottoriva, Simon J Leedham, Trevor A Graham, Ian P M Tomlinson
The evolutionary landscape of colorectal tumorigenesis. Nature ecology & evolution 2 (10) (2018)
Marc J Williams, Benjamin Werner, Timon Heide, Christina Curtis, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham
Quantification of subclonal selection in cancer from bulk sequencing data. Nature genetics 50 (6) (2018)
Giulio Caravagna, Ylenia Giarratano, Daniele Ramazzotti, Ian P M Tomlinson, Trevor A Graham, Guido Sanguinetti, Andrea Sottoriva
Detecting repeated cancer evolution from multi-region tumor sequencing data. Nature methods 15 (9) (2018)
Ann-Marie Baker, Weini Huang, Xiao-Ming Mindy Wang, Marnix Jansen, Xiao-Jun Ma, Jeffrey Kim, Courtney M Anderson, Xingyong Wu, Liuliu Pan, Nan Su, Yuling Luo, Enric Domingo, Timon Heide, Andrea Sottoriva, Annabelle Lewis, Andrew D Beggs, Nicholas A Wright, Manuel Rodriguez-Justo, Emily Park, Ian P M Tomlinson, Trevor A Graham
Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nature communications 8 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Andrea Sottoriva