Mark Lautens

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 58

Top Venues

Organic letters

Angewandte Chemie (International ed. in English)

Journal of the American Chemical Society

Nature communications

University of Toronto

University of Wisconsin Madison (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto Jul 01 1987

Canada

University Professor :: Chemistry

Education History

University of Wisconsin Madison May 01 1981 - Jun 30 1985

United States

PHD :: Chemistry

Publications

Jessica Knox, Andrew R Burns, Brittany Cooke, Savina R Cammalleri, Megan Kitner, Justin Ching, Jack M P Castelli, Emily Puumala, Jamie Snider, Emily J Koury, James Bryant Collins, Salma Geissah, James E Dowling, Erik C Andersen, Igor Stagljar, Leah E Cowen, Mark Lautens, Inga Zasada, Peter J Roy
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation. Nature communications 15 (1) (2024)
Jessica Knox, Andrew R Burns, Brittany Cooke, Savina R Cammalleri, Megan Kitner, Justin Ching, Jack M P Castelli, Emily Puumala, Jamie Snider, Emily J Koury, James Bryant Collins, Salma Geissah, James E Dowling, Erik C Andersen, Igor Stagljar, Leah E Cowen, Mark Lautens, Inga Zasada, Peter J Roy
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation. Nature communications 15 (1) (2024)
Jessica Knox, Andrew R Burns, Brittany Cooke, Savina R Cammalleri, Megan Kitner, Justin Ching, Jack M P Castelli, Emily Puumala, Jamie Snider, Emily J Koury, James Bryant Collins, Salma Geissah, James E Dowling, Erik C Andersen, Igor Stagljar, Leah E Cowen, Mark Lautens, Inga Zasada, Peter J Roy
Cyprocide selectively kills nematodes via cytochrome P450 bioactivation. Nature communications 15 (1) (2024)
Xavier Abel-Snape, Colton E Johnson, Bianca Imbriaco, Mark Lautens
Synthesis of spirooxindoles via formal acetylene insertion into a common palladacycle intermediate. Chemical science 14 (21) (2023)
Eric N Donders, Kai V Slaughter, Christian Dank, Ahil N Ganesh, Brian K Shoichet, Mark Lautens, Molly S Shoichet
Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal Disruption. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Ramon Arora, Bijan Mirabi, Andrew G Durant, Carlota Bozal-Ginesta, Austin D Marchese, Alán Aspuru-Guzik, Mark Lautens
Palladium-Catalyzed Synthesis of Linked Bis-Heterocycles─Synthesis and Investigation of Photophysical Properties. Journal of the American Chemical Society (2023)
Sean Harrington, Jacob Pyche, Andrew R Burns, Tina Spalholz, Kaetlyn T Ryan, Rachel J Baker, Justin Ching, Lucien Rufener, Mark Lautens, Daniel Kulke, Alexandre Vernudachi, Mostafa Zamanian, Winnie Deuther-Conrad, Peter Brust, Peter J Roy
Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential. Nature communications 14 (1) (2023)
Eric N Donders, Kai V Slaughter, Christian Dank, Ahil N Ganesh, Brian K Shoichet, Mark Lautens, Molly S Shoichet
Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal Disruption. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Sean Harrington, Jacob Pyche, Andrew R Burns, Tina Spalholz, Kaetlyn T Ryan, Rachel J Baker, Justin Ching, Lucien Rufener, Mark Lautens, Daniel Kulke, Alexandre Vernudachi, Mostafa Zamanian, Winnie Deuther-Conrad, Peter Brust, Peter J Roy
Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential. Nature communications 14 (1) (2023)
Ramon Arora, Jonathan Bajohr, Mark Lautens
Rapid Assembly of Unsymmetrically Linked Bis-heterocycles via Palladium Domino Catalysis. Organic letters (2023)
Rachel J Harding, Ivan Franzoni, Mandeep K Mann, Magdalena M Szewczyk, Bijan Mirabi, Renato Ferreira de Freitas, Dominic D G Owens, Suzanne Ackloo, Alexej Scheremetjew, Kevin A Juarez-Ornelas, Randy Sanichar, Rachel J Baker, Christian Dank, Peter J Brown, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Matthieu Schapira, Mark Lautens, Cheryl H Arrowsmith
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. Journal of medicinal chemistry (2023)
Jonathan Bajohr, Aurélien Dupeux, Daniel Schenk, Clara Jans, Mark Lautens
Pd-Catalyzed Domino Narasaka-Heck/C-H Activation/Amination Reactions: Synthesis of Bis-heterocyclic Spirocycles. Organic letters (2023)
E Ali McKnight, Ramon Arora, Ekadashi Pradhan, Yuriko H Fujisato, Ayonitemi J Ajayi, Mark Lautens, Tao Zeng, Christine M Le
BF 3 -Catalyzed Intramolecular Fluorocarbamoylation of Alkynes via Halide Recycling. Journal of the American Chemical Society (2023)
Esther G Kaye, Bijan Mirabi, Ivonne R Lopez-Miranda, Komadhie C Dissanayake, Upasana Banerjee, Madelyn Austin, Mark Lautens, Arthur H Winter, Andrew A Beharry
Photo-Uncaging by C(sp 3 )-C(sp 3 ) Bond Cleavage Restores β-Lapachone Activity. Journal of the American Chemical Society (2023)
Alexa Torelli, Eun Seo Choi, Aurélien Dupeux, Marcel Nicolas Perner, Mark Lautens
Stereoselective Kinugasa/Aldol Cyclization: Synthesis of Enantioenriched Spirocyclic β-Lactams. Organic letters (2023)
Andrew R Burns, Rachel J Baker, Megan Kitner, Jessica Knox, Brittany Cooke, Jonathan R Volpatti, Aditya S Vaidya, Emily Puumala, Bruna M Palmeira, Elizabeth M Redman, Jamie Snider, Sagar Marwah, Sai W Chung, Margaret H MacDonald, Jens Tiefenbach, Chun Hu, Qi Xiao, Constance A M Finney, Henry M Krause, Sonya A MacParland, Igor Stagljar, John S Gilleard, Leah E Cowen, Susan L F Meyer, Sean R Cutler, James E Dowling, Mark Lautens, Inga Zasada, Peter J Roy
Selective control of parasitic nematodes using bioactivated nematicides. Nature (2023)
E Ali McKnight, Ramon Arora, Ekadashi Pradhan, Yuriko H Fujisato, Ayonitemi J Ajayi, Mark Lautens, Tao Zeng, Christine M Le
BF 3 -Catalyzed Intramolecular Fluorocarbamoylation of Alkynes via Halide Recycling. Journal of the American Chemical Society (2023)
Austin D Marchese, Bijan Mirabi, Colton E Johnson, Mark Lautens
Reversible C-C bond formation using palladium catalysis. Nature chemistry 14 (4) (2022)
Austin D Marchese, Andrew G Durant, Cian M Reid, Clara Jans, Ramon Arora, Mark Lautens
Pd(0)/Blue Light Promoted Carboiodination Reaction - Evidence for Reversible C-I Bond Formation via a Radical Pathway. Journal of the American Chemical Society 144 (45) (2022)
Jonathan Bajohr, Matthias D Böhme, Jiacheng Gao, F Ekkehardt Hahn, Mark Lautens
Palladium-Catalyzed Three-Component Dearomatization/Sulfonylation Cascade. Organic letters 24 (21) (2022)
Rachel J Baker, Justin Ching, Teh Ren Hou, Ivan Franzoni, Mark Lautens
Dearomative Cyclopropanation of Naphthols via Cyclopropene Ring-Opening. Angewandte Chemie (International ed. in English) 61 (8) (2022)
Andrew Whyte, Jonathan Bajohr, Ramon Arora, Alexa Torelli, Mark Lautens
Sequential Pd0 - and PdII -Catalyzed Cyclizations: Enantioselective Heck and Nucleopalladation Reactions. Angewandte Chemie (International ed. in English) 60 (37) (2021)
Ken-Loon Choo, Bijan Mirabi, Karl Z Demmans, Mark Lautens
Enantioselective Synthesis of Spiro-oxiranes: An Asymmetric Addition/Aldol/Spirocyclization Domino Cascade. Angewandte Chemie (International ed. in English) 60 (39) (2021)
Ramon Arora, José F Rodríguez, Andrew Whyte, Mark Lautens
Accessing Unsymmetrically Linked Heterocycles through Stereoselective Palladium-Catalyzed Domino Cyclization. Angewandte Chemie (International ed. in English) (2021)
Joachim Loup, Egor M Larin, Mark Lautens
Iron-Catalyzed Reductive Cyclization by Hydromagnesiation: A Modular Strategy Towards N-Heterocycles. Angewandte Chemie (International ed. in English) 60 (41) (2021)
Jonathan Bajohr, Abdoul G Diallo, Andrew Whyte, Sylvain Gaillard, Jean-Luc Renaud, Mark Lautens
Palladium-Catalyzed Domino Heck/Sulfination: Synthesis of Sulfonylated Hetero- and Carbocyclic Scaffolds Using DABCO-Bis(sulfur dioxide). Organic letters 23 (7) (2021)
Austin D Marchese, Timur Adrianov, Mark Lautens
Recent Strategies for Carbon-Halogen Bond Formation Using Nickel. Angewandte Chemie (International ed. in English) 60 (31) (2021)
Egor M Larin, Alexa Torelli, Joachim Loup, Mark Lautens
One-Pot, Three-Step Synthesis of Benzoxazinones via Use of the Bpin Group as a Masked Nucleophile. Organic letters 23 (7) (2021)
Jeanne Masson-Makdissi, Liher Prieto, Xavier Abel-Snape, Mark Lautens
Enantio- and Diastereodivergent Sequential Catalysis Featuring Two Transition-Metal-Catalyzed Asymmetric Reactions. Angewandte Chemie (International ed. in English) 60 (31) (2021)
Austin D Marchese, Andrew G Durant, Mark Lautens
A Modular Approach for the Palladium-Catalyzed Synthesis of Bis-heterocyclic Spirocycles. Organic letters 24 (1) (2021)
José F Rodríguez, Anji Zhang, Jonathan Bajohr, Andrew Whyte, Bijan Mirabi, Mark Lautens
Cycloisomerization of Carbamoyl Chlorides in Hexafluoroisopropanol: Stereoselective Synthesis of Chlorinated Methylene Oxindoles and Quinolinones. Angewandte Chemie (International ed. in English) 60 (34) (2021)
José F Rodríguez, Anji Zhang, Ramon Arora, Mark Lautens
Synthesis of 1-Amino-2,2,2-trifluoroalkylphosphonates from Alkene-Tethered Trifluoroacetimidoyl Chlorides. Organic letters 23 (19) (2021)
Andrew Whyte, Jonathan Bajohr, Alexa Torelli, Mark Lautens
Enantioselective Cobalt-Catalyzed Intermolecular Hydroacylation of 1,6-Enynes. Angewandte Chemie (International ed. in English) 59 (38) (2020)
Nicolas Zeidan, Matthew Zambri, Sven Unger, Christian Dank, Alexa Torelli, Bijan Mirabi, Mark Lautens
Synthesis and Reactions of 3,3-Difluoro-2-exo-methylidene Indolines. Organic letters 22 (9) (2020)
Xavier Abel-Snape, Andrew Whyte, Mark Lautens
Synthesis of Aminated Phenanthridinones via Palladium/Norbornene Catalysis. Organic letters 22 (20) (2020)
Alexa Torelli, Andrew Whyte, Iuliia Polishchuk, Jonathan Bajohr, Mark Lautens
Stereoselective Construction of γ-Lactams via Copper-Catalyzed Borylacylation. Organic letters 22 (20) (2020)
Abdoul G Diallo, David Roy, Sylvain Gaillard, Mark Lautens, Jean-Luc Renaud
Aminomethylation of Oxabenzonorbornadienes via the Merger of Photoredox and Nickel Catalysis. Organic letters 22 (6) (2020)
Marco Wollenburg, Jonathan Bajohr, Austin D Marchese, Andrew Whyte, Frank Glorius, Mark Lautens
Palladium-Catalyzed Disilylation and Digermanylation of Alkene Tethered Aryl Halides: Direct Access to Versatile Silylated and Germanylated Heterocycles. Organic letters 22 (9) (2020)
Rachel J Baker, Rubaishan Jeyaseelan, Mark Lautens
Rhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening. Organic letters 22 (12) (2020)
Andrew Whyte, Alexa Torelli, Bijan Mirabi, Liher Prieto, José F Rodríguez, Mark Lautens
Cobalt-Catalyzed Enantioselective Hydroarylation of 1,6-Enynes. Journal of the American Chemical Society 142 (20) (2020)
Austin D Marchese, Egor M Larin, Bijan Mirabi, Mark Lautens
Metal-Catalyzed Approaches toward the Oxindole Core. Accounts of chemical research 53 (8) (2020)
Egor M Larin, Joachim Loup, Iuliia Polishchuk, Rachel J Baker, Andrew Whyte, Mark Lautens
Enantio- and diastereoselective conjugate borylation/Mannich cyclization. Chemical science 11 (22) (2020)
Egor M Larin, Mark Lautens
Intramolecular Copper(I)-Catalyzed Interrupted Click-Acylation Domino Reaction. Angewandte Chemie (International ed. in English) 58 (38) (2019)
Andrew Whyte, Alexa Torelli, Bijan Mirabi, Mark Lautens
Enantioselective Copper-Catalyzed Borylative Cyclization with Cyclic Imides. Organic letters 21 (20) (2019)
Andy Yen, Anh Hoang Pham, Egor M Larin, Mark Lautens
Rhodium-Catalyzed Enantioselective Synthesis of Oxazinones via an Asymmetric Ring Opening-Lactonization Cascade of Oxabicyclic Alkenes. Organic letters 21 (18) (2019)
Austin D Marchese, Florian Lind, Áine E Mahon, Hyung Yoon, Mark Lautens
Forming Benzylic Iodides via a Nickel Catalyzed Diastereoselective Dearomative Carboiodination Reaction of Indoles. Angewandte Chemie (International ed. in English) 58 (15) (2019)
Austin D Marchese, Louise Kersting, Mark Lautens
Diastereoselective Nickel-Catalyzed Carboiodination Generating Six-Membered Nitrogen-Based Heterocycles. Organic letters 21 (17) (2019)
Hyung Yoon, Austin D Marchese, Mark Lautens
Carboiodination Catalyzed by Nickel. Journal of the American Chemical Society 140 (35) (2018)
Heather Lam, Zafar Qureshi, Marcus Wegmann, Mark Lautens
Transition-Metal-Free [4+3]-Cycloaddition of ortho-Quinone Methides and Isomünchnones: Catalytic and Diastereoselective Assembly of Oxa-bridged Oxazocine Scaffolds. Angewandte Chemie (International ed. in English) 57 (49) (2018)
Nicolas Zeidan, Tamara Beisel, Rachel Ross, Mark Lautens
Palladium-Catalyzed Arylation/Heteroarylation of Indoles: Access to 2,3-Functionalized Indolines. Organic letters 20 (22) (2018)
Andy Yen, Mark Lautens
Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles. Organic letters 20 (14) (2018)
José F Rodríguez, Austin D Marchese, Mark Lautens
Palladium-Catalyzed Synthesis of Dihydrobenzoindolones via C-H Bond Activation and Alkyne Insertion. Organic letters 20 (14) (2018)
Renato Ferreira de Freitas, Rachel J Harding, Ivan Franzoni, Mani Ravichandran, Mandeep K Mann, Hui Ouyang, Mark Lautens, Vijayaratnam Santhakumar, Cheryl H Arrowsmith, Matthieu Schapira
Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors. Journal of medicinal chemistry 61 (10) (2018)
José F Rodríguez, Katherine I Burton, Ivan Franzoni, David A Petrone, Ina Scheipers, Mark Lautens
Palladium-Catalyzed Hydride Addition/C-H Bond Activation Cascade: Cycloisomerization of 1,6-Diynes. Organic letters 20 (21) (2018)
Young Jin Jang, Daniel Rose, Bijan Mirabi, Mark Lautens
Rhodium-Catalyzed Enantioselective Defluorinative α-Arylation of Secondary Amides. Angewandte Chemie (International ed. in English) 57 (49) (2018)
Andrew Whyte, Katherine I Burton, Jingli Zhang, Mark Lautens
Enantioselective Intramolecular Copper-Catalyzed Borylacylation. Angewandte Chemie (International ed. in English) 57 (42) (2018)
Andy Yen, Ken-Loon Choo, Shabnam K Yazdi, Patrick T Franke, Robert Webster, Ivan Franzoni, Charles C J Loh, Amalia I Poblador-Bahamonde, Mark Lautens
Rhodium-Catalyzed Enantioselective Isomerization of meso-Oxabenzonorbornadienes to 1,2-Naphthalene Oxides. Angewandte Chemie (International ed. in English) 56 (22) (2017)
David A Petrone, Masaru Kondo, Nicolas Zeidan, Mark Lautens
Pd(0)-Catalyzed Dearomative Diarylation of Indoles. Chemistry (Weinheim an der Bergstrasse, Germany) 22 (16) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Mark Lautens