Michael J Roy

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 9

Top Topics

Metal Organic Framework

Lymph Node Metastasis

Top Venues

Nature communications

Science signaling

Nature chemical biology

Nature structural & molecular biology

This page only lists publications with an associated author ORCID identifier.

Publications

Michael J Roy, Minglyanna G Surudoi, Ashleigh Kropp, Jianmei Hou, Weiwen Dai, Joshua M Hardy, Lung-Yu Liang, Thomas R Cotton, Bernhard C Lechtenberg, Toby A Dite, Xiuquan Ma, Roger J Daly, Onisha Patel, Isabelle S Lucet
Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nature communications 14 (1) (2023)
Michelle S Miller, Angus D Cowan, Jason M Brouwer, Sean T Smyth, Liuyu Peng, Ahmad Z Wardak, Rachel T Uren, Cindy Luo, Michael J Roy, Sayali Shah, Ziwen Tan, Gavin E Reid, Peter M Colman, Peter E Czabotar
Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. The FEBS journal (2023)
Christiane Kofink, Nicole Trainor, Barbara Mair, Simon Wöhrle, Melanie Wurm, Nikolai Mischerikow, Michael J Roy, Gerd Bader, Peter Greb, Géraldine Garavel, Emelyne Diers, Ross McLennan, Claire Whitworth, Vesna Vetma, Klaus Rumpel, Maximilian Scharnweber, Julian E Fuchs, Thomas Gerstberger, Yunhai Cui, Gabriela Gremel, Paolo Chetta, Stefan Hopf, Nicole Budano, Joerg Rinnenthal, Gerhard Gmaschitz, Moriz Mayer, Manfred Koegl, Alessio Ciulli, Harald Weinstabl, William Farnaby
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo. Nature communications 13 (1) (2022)
Jianmei Hou, Elizabeth V Nguyen, Minglyanna G Surudoi, Michael J Roy, Onisha Patel, Isabelle S Lucet, Xiuquan Ma, Roger J Daly
Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family. Science signaling 15 (722) (2022)
Michael J Roy, Amelia Vom, Toru Okamoto, Brian J Smith, Richard W Birkinshaw, Hong Yang, Houda Abdo, Christine A White, David Segal, David C S Huang, Jonathan B Baell, Peter M Colman, Peter E Czabotar, Guillaume L Lessene
Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2. Journal of medicinal chemistry 64 (9) (2021)
Onisha Patel, Michael J Roy, Ashleigh Kropp, Joshua M Hardy, Weiwen Dai, Isabelle S Lucet
Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Communications biology 4 (1) (2021)
Runyu Mao, Shiyi Xi, Sayali Shah, Michael J Roy, Alan John, James P Lingford, Gerd Gäde, Nichollas E Scott, Ethan D Goddard-Borger
Synthesis of C-Mannosylated Glycopeptides Enabled by Ni-Catalyzed Photoreductive Cross-Coupling Reactions. Journal of the American Chemical Society 143 (32) (2021)
Angus D Cowan, Nicholas A Smith, Jarrod John Sandow, Eugene A Kapp, Yepy Hardi Rustam, James G Murphy, Jason M Brouwer, Jonathan P Bernardini, Michael J Roy, Ahmad Z Wardak, Iris K Tan, Andrew Ian Webb, Jacqueline M Gulbis, Brian J Smith, Gavin E Reid, Grant Dewson, Peter M Colman, Peter E Czabotar
BAK core dimers bind lipids and can be bridged by them. Nature structural & molecular biology 27 (11) (2020)
William Farnaby, Manfred Koegl, Michael J Roy, Claire Whitworth, Emelyne Diers, Nicole Trainor, David Zollman, Steffen Steurer, Jale Karolyi-Oezguer, Carina Riedmueller, Teresa Gmaschitz, Johannes Wachter, Christian Dank, Michael Galant, Bernadette Sharps, Klaus Rumpel, Elisabeth Traxler, Thomas Gerstberger, Renate Schnitzer, Oliver Petermann, Peter Greb, Harald Weinstabl, Gerd Bader, Andreas Zoephel, Alexander Weiss-Puxbaum, Katharina Ehrenhöfer-Wölfer, Simon Wöhrle, Guido Boehmelt, Joerg Rinnenthal, Heribert Arnhof, Nicola Wiechens, Meng-Ying Wu, Tom Owen-Hughes, Peter Ettmayer, Mark Pearson, Darryl B McConnell, Alessio Ciulli
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nature chemical biology 15 (7) (2019)