René E M Toes (René Em Toes, Rem Toes, René Toes, R E M Toes, Rene E M Toes)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 55

Top Topics

Rheumatoid Arthritis

Histone Deacetylase

Basal Cell Carcinoma

Acute Lymphoblastic Leukemia

Top Venues

Annals of the rheumatic diseases

Nature communications

Journal of immunology (Baltimore, Md. : 1950)

This page only lists publications with an associated author ORCID identifier.

Publications

Diane van der Woude, René E M Toes
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special? Annals of the rheumatic diseases (2024)
Theresa Kissel, Veerle F A M Derksen, Arthur E H Bentlage, Carolien Koeleman, Lise Hafkenscheid, Diane van der Woude, Dana L E Vergoossen, Gestur Vidarsson, René E M Toes
N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line. Nature communications 15 (1) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Theresa Kissel, Veerle F A M Derksen, Arthur E H Bentlage, Carolien Koeleman, Lise Hafkenscheid, Diane van der Woude, Dana L E Vergoossen, Gestur Vidarsson, René E M Toes
N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line. Nature communications 15 (1) (2024)
Mikhail Y Volkov, Arieke Suzanna Berendina Kampstra, Karin A J van Schie, Anouk G van Mourik, Joanneke C Kwekkeboom, Arnoud de Ru, Peter A van Veelen, Thomas Wj Huizinga, René E M Toes, Diane van der Woude
Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response. RMD open 10 (3) (2024)
Diane van der Woude, René E M Toes
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special? Annals of the rheumatic diseases 83 (7) (2024)
Theresa Kissel, Veerle F A M Derksen, Arthur E H Bentlage, Carolien Koeleman, Lise Hafkenscheid, Diane van der Woude, Dana L E Vergoossen, Gestur Vidarsson, René E M Toes
N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line. Nature communications 15 (1) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Johannes Hendrick von Hegedus, Anja J de Jong, Anna T Hoekstra, Eric Spronsen, Wahwah Zhu, Birol Cabukusta, Joanneke C Kwekkeboom, Marieke Heijink, Erik Bos, Celia R Berkers, Martin A Giera, René E M Toes, Andreea Ioan-Facsinay
Oleic acid enhances proliferation and calcium mobilization of CD3/CD28 activated CD4 + T cells through incorporation into membrane lipids. European journal of immunology (2024)
Mikhail Y Volkov, Arieke Suzanna Berendina Kampstra, Karin A J van Schie, Anouk G van Mourik, Joanneke C Kwekkeboom, Arnoud de Ru, Peter A van Veelen, Thomas Wj Huizinga, René E M Toes, Diane van der Woude
Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response. RMD open 10 (3) (2024)
Sarah J H Khidir, René E M Toes, Elise van Mulligen, Annette H M van der Helm van Mil
Is tooth extraction as proxy for periodontal disease related to the development of RA? Lessons from a longitudinal study in the at-risk stage of clinically suspect arthralgia. Annals of the rheumatic diseases 83 (9) (2024)
Mikhail Y Volkov, Arieke Suzanna Berendina Kampstra, Karin A J van Schie, Anouk G van Mourik, Joanneke C Kwekkeboom, Arnoud de Ru, Peter A van Veelen, Thomas Wj Huizinga, René E M Toes, Diane van der Woude
Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response. RMD open 10 (3) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Diane van der Woude, René E M Toes
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special? Annals of the rheumatic diseases 83 (7) (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Sarah J H Khidir, René E M Toes, Elise van Mulligen, Annette H M van der Helm van Mil
Is tooth extraction as proxy for periodontal disease related to the development of RA? Lessons from a longitudinal study in the at-risk stage of clinically suspect arthralgia. Annals of the rheumatic diseases (2024)
Eva Maria Stork, Danique M H van Rijswijk, Karin Anna van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Thomas Wj Huizinga, Albert J R Heck, René E M Toes, Albert Bondt
Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature communications 15 (1) (2024)
Theresa Kissel, René E M Toes, Thomas W J Huizinga, Dana L E Vergoossen
Author Correction: Glycobiology of rheumatic diseases. Nature reviews. Rheumatology (2023)
Michelle D van den Beukel, Tineke J van Wesemael, Anna Titia W Hoogslag, Nicole V Borggreven, Thomas Wj Huizinga, Annette H M van der Helm van Mil, René E M Toes, Diane van der Woude, Leendert Adrianus Trouw
Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association. RMD open 9 (4) (2023)
Yibo He, Changrong Ge, Àlex Moreno-Giró, Bingze Xu, Christian Michel Beusch, Katalin Sandor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I Svensson, Hans Ulrich Scherer, René E M Toes, Inger Gjertsson, Olov Ekwall, Roman A Zubarev, Rickard Holmdahl
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nature communications 14 (1) (2023)
Yibo He, Changrong Ge, Àlex Moreno-Giró, Bingze Xu, Christian Michel Beusch, Katalin Sandor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I Svensson, Hans Ulrich Scherer, René E M Toes, Inger Gjertsson, Olov Ekwall, Roman A Zubarev, Rickard Holmdahl
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nature communications 14 (1) (2023)
Catherine D Hughes, Sarah E Ryan, Kathryn J A Steel, Michelle D van den Beukel, Leendert Adrianus Trouw, Karin A J van Schie, René E M Toes, Bina Menon, Bruce W Kirkham, Leonie S Taams
Type 17-specific immune pathways are active in early spondyloarthritis. RMD open 9 (4) (2023)
Catherine D Hughes, Sarah E Ryan, Kathryn J A Steel, Michelle D van den Beukel, Leendert Adrianus Trouw, Karin A J van Schie, René E M Toes, Bina Menon, Bruce W Kirkham, Leonie S Taams
Type 17-specific immune pathways are active in early spondyloarthritis. RMD open 9 (4) (2023)
Tineke J van Wesemael, Sanne Reijm, Atsushi Kawakami, Annemarie L Dorjée, Gerrie Stoeken, Takahiro Maeda, Shin-Ya Kawashiri, Thomas Wj Huizinga, Mami Tamai, René E M Toes, Diane van der Woude
IgM antibodies against acetylated proteins as a possible starting point of the anti-modified protein antibody response in rheumatoid arthritis. Annals of the rheumatic diseases (2023)
Sophie I E Liem, Sam Neppelenbroek, Cynthia M Fehres, Brigitte A Wevers, René E M Toes, Cornelia F Allaart, Thomas Wj Huizinga, Hans Ulrich Scherer, Jeska K De Vries-Bouwstra
Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies. RMD open 9 (1) (2023)
Sophie I E Liem, Sam Neppelenbroek, Cynthia M Fehres, Brigitte A Wevers, René E M Toes, Cornelia F Allaart, Thomas Wj Huizinga, Hans Ulrich Scherer, Jeska K De Vries-Bouwstra
Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies. RMD open 9 (1) (2023)
Sophie I E Liem, Sam Neppelenbroek, Cynthia M Fehres, Brigitte A Wevers, René E M Toes, Cornelia F Allaart, Thomas Wj Huizinga, Hans Ulrich Scherer, Jeska K De Vries-Bouwstra
Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies. RMD open 9 (1) (2023)
Yibo He, Changrong Ge, Àlex Moreno-Giró, Bingze Xu, Christian Michel Beusch, Katalin Sandor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I Svensson, Hans Ulrich Scherer, René E M Toes, Inger Gjertsson, Olov Ekwall, Roman A Zubarev, Rickard Holmdahl
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nature communications 14 (1) (2023)
Catherine D Hughes, Sarah E Ryan, Kathryn J A Steel, Michelle D van den Beukel, Leendert Adrianus Trouw, Karin A J van Schie, René E M Toes, Bina Menon, Bruce W Kirkham, Leonie S Taams
Type 17-specific immune pathways are active in early spondyloarthritis. RMD open 9 (4) (2023)
Yibo He, Changrong Ge, Àlex Moreno-Giró, Bingze Xu, Christian Michel Beusch, Katalin Sandor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I Svensson, Hans Ulrich Scherer, René E M Toes, Inger Gjertsson, Olov Ekwall, Roman A Zubarev, Rickard Holmdahl
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nature communications 14 (1) (2023)
Yibo He, Changrong Ge, Àlex Moreno-Giró, Bingze Xu, Christian Michel Beusch, Katalin Sandor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I Svensson, Hans Ulrich Scherer, René E M Toes, Inger Gjertsson, Olov Ekwall, Roman A Zubarev, Rickard Holmdahl
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nature communications 14 (1) (2023)
Sophie I E Liem, Sam Neppelenbroek, Cynthia M Fehres, Brigitte A Wevers, René E M Toes, Cornelia F Allaart, Thomas Wj Huizinga, Hans Ulrich Scherer, Jeska K De Vries-Bouwstra
Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies. RMD open 9 (1) (2023)
Corrie M Wortel, Sophie I E Liem, Nina Marijn van Leeuwen, Maaike Boonstra, Cynthia M Fehres, Lauran Stöger, Thomas Wj Huizinga, René E M Toes, Jeska De Vries-Bouwstra, Hans Ulrich Scherer
Anti-topoisomerase, but not anti-centromere B cell responses in systemic sclerosis display active, Ig-secreting cells associated with lung fibrosis. RMD open 9 (3) (2023)
Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C Kwekkeboom, Linda M Slot, Marco Cavallari, Yibo He, Karin Anna van Schie, Rochelle D Vergroesen, Arieke Suzanna Berendina Kampstra, Sanne Reijm, Gerrie Stoeken-Rijsbergen, Carolien A M Koeleman, Lennard M Voortman, Laura H Heitman, Bingze Xu, Ger J M Pruijn, Dana L E Vergoossen, Theo Rispens, Thomas Wj Huizinga, Hans Ulrich Scherer, Michael Reth, Rickard Holmdahl, René E M Toes
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation. Science advances 8 (6) (2022)
Theresa Kissel, René E M Toes, Thomas W J Huizinga, Dana L E Vergoossen
Glycobiology of rheumatic diseases. Nature reviews. Rheumatology (2022)
Mikhail Y Volkov, Maximilian Brinkhaus, Karin Anna van Schie, Albert Bondt, Theresa Kissel, Elvera J van der Kooi, Arthur E H Bentlage, Carolien A M Koeleman, Steven W de Taeye, Ninotska I L Derksen, Radboud J E M Dolhain, Ute Braig-Scherer, Tom W J Huizinga, Dana L E Vergoossen, René E M Toes, Gestur Vidarsson, Diane van der Woude
IgG Fab Glycans Hinder FcRn-Mediated Placental Transport. Journal of immunology (Baltimore, Md. : 1950) (2022)
Sanne Reijm, Astrid S Brehler, Solbritt Rantapää Dahlqvist, Atsushi Kawakami, Takahiro Maeda, Shin-Ya Kawashiri, Mami Tamai, Diane van der Woude, René E M Toes
Cross-reactivity of anti-modified protein antibodies is also present in predisease and individuals without rheumatoid arthritis. Annals of the rheumatic diseases (2022)
Nienke Oskam, Pleuni Ooijevaar-de Heer, Ninotska I L Derksen, Simone Kruithof, Steven W de Taeye, Gestur Vidarsson, Sanne Reijm, Theresa Kissel, René E M Toes, Theo Rispens
At Critically Low Antigen Densities, IgM Hexamers Outcompete Both IgM Pentamers and IgG1 for Human Complement Deposition and Complement-Dependent Cytotoxicity. Journal of immunology (Baltimore, Md. : 1950) 209 (1) (2022)
Hans Ulrich Scherer, Diane van der Woude, René E M Toes
From risk to chronicity: evolution of autoreactive B cell and antibody responses in rheumatoid arthritis. Nature reviews. Rheumatology 18 (7) (2022)
Theresa Kissel, Tineke J van Wesemael, Anders Lundquist, Heidi Kokkonen, Atsushi Kawakami, Mami Tamai, Dirkjan van Schaardenburg, Manfred Wuhrer, Thomas Wj Huizinga, Hans Ulrich Scherer, Diane van der Woude, Solbritt Rantapää Dahlqvist, René E M Toes
Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA. Annals of the rheumatic diseases (2021)
Veerle F A M Derksen, Theresa Kissel, Femke B G Lamers-Karnebeek, Arie E van der Bijl, Annemarie C Venhuizen, Thomas Wj Huizinga, René E M Toes, Anna H E Roukens, Diane van der Woude
Onset of rheumatoid arthritis after COVID-19: coincidence or connected? Annals of the rheumatic diseases (2021)
Fenne Wouters, Marc P Maurits, Laurette van Boheemen, Marloes Verstappen, Kulveer Mankia, Xanthe Marijn Edmée Matthijssen, Annemarie L Dorjée, Paul Emery, Rachel Knevel, Dirkjan van Schaardenburg, René E M Toes, Annette H M van der Helm van Mil
Determining in which pre-arthritis stage HLA-shared epitope alleles and smoking exert their effect on the development of rheumatoid arthritis. Annals of the rheumatic diseases (2021)
Hendy Kristyanto, Nienke J Blomberg, Linda M Slot, Ellen I H van der Voort, Priscilla F Kerkman, Aleida Bakker, Leonie E Burgers, Robin M Ten Brinck, Annette H M van der Helm-van Mil, Hergen Spits, Dominique L Baeten, Thomas Wj Huizinga, René E M Toes, Hans Ulrich Scherer
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis. Science translational medicine 12 (570) (2021)
Fenne Wouters, Ellis Niemantsverdriet, Nazike Salioska, Annemarie L Dorjée, René E M Toes, Annette H M van der Helm van Mil
Do autoantibody-responses mature between presentation with arthralgia suspicious for progression to rheumatoid arthritis and development of clinically apparent inflammatory arthritis? A longitudinal serological study. Annals of the rheumatic diseases (2020)
Hilde Brouwers, Hulda S Jónasdóttir, Marije E Kuipers, Joanneke C Kwekkeboom, Jennifer L Auger, Mayra Gonzalez-Torres, Cristina López-Vicario, Joan Claria, Jona Freysdottir, Ingibjorg Hardardottir, Jose Garrido Mesa, Lucy Victoria Norling, Mauro Perretti, Tom W J Huizinga, Margreet Kloppenburg, René E M Toes, Bryce A Binstadt, Martin A Giera, Andreea Ioan-Facsinay
Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid. Journal of immunology (Baltimore, Md. : 1950) 205 (10) (2020)
Theresa Kissel, S Reijm, L M Slot, M Cavallari, C M Wortel, R D Vergroesen, G Stoeken-Rijsbergen, J C Kwekkeboom, Arieke Suzanna Berendina Kampstra, Ewn Levarht, J W Drijfhout, H Bang, K M Bonger, Gmc Janssen, P A van Veelen, Thomas Wj Huizinga, H U Scherer, M Reth, René E M Toes
Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications. Annals of the rheumatic diseases 79 (4) (2020)
Sanne Reijm, Theresa Kissel, René E M Toes
Checkpoints controlling the induction of B cell mediated autoimmunity in human autoimmune diseases. European journal of immunology 50 (12) (2020)
René E M Toes, David S Pisetsky
Response to: 'Comment on editorial 'Pathogenic effector functions of ACPA: where do we stand'' by Holmdahl. Annals of the rheumatic diseases 79 (10) (2019)
René E M Toes, David S Pisetsky
Response to: "How to communicate in science" by Klareskog et al. Annals of the rheumatic diseases 79 (12) (2019)
Arieke Suzanna Berendina Kampstra, Jacqueline Stephanie Dekkers, Mikhail Volkov, Annemarie L Dorjée, Lise Hafkenscheid, Ayla C Kempers, Myrthe van Delft, Theresa Kissel, Sanne Reijm, George M C Janssen, Peter A van Veelen, Holger Bang, Tom W J Huizinga, Leendert A Trouw, Diane van der Woude, René E M Toes
Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification. Annals of the rheumatic diseases 78 (7) (2019)
Debbie M Boeters, Leonie E Burgers, René E M Toes, Annette van der Helm-van Mil
Does immunological remission, defined as disappearance of autoantibodies, occur with current treatment strategies? A long-term follow-up study in rheumatoid arthritis patients who achieved sustained DMARD-free status. Annals of the rheumatic diseases 78 (11) (2019)
René E M Toes, David S Pisetsky
Pathogenic effector functions of ACPA: Where do we stand? Annals of the rheumatic diseases 78 (6) (2019)
Theresa Kissel, Karin Anna van Schie, Lise Hafkenscheid, Anders Lundquist, Heidi Kokkonen, Manfred Wuhrer, Tom Wj Huizinga, Hans Ulrich Scherer, René E M Toes, Solbritt Rantapää Dahlqvist
On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis. Annals of the rheumatic diseases 78 (12) (2019)
Emma C de Moel, Elisa A Rozeman, Ellen H Kapiteijn, Els M E Verdegaal, Annette Grummels, Jaap Adriaan Bakker, Tom W J Huizinga, John B Haanen, René E M Toes, Diane van der Woude
Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors. Cancer immunology research 7 (1) (2018)
Jolien Suurmond, Kim L L Habets, Annemarie L Dorjée, Tom W Huizinga, René E M Toes
Expansion of Th17 Cells by Human Mast Cells Is Driven by Inflammasome-Independent IL-1β. Journal of immunology (Baltimore, Md. : 1950) 197 (11) (2016)