Richard A Flavell (Richard Flavell)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 117

Top Venues

Nature communications

Nature

Science immunology

Cell death and differentiation

This page only lists publications with an associated author ORCID identifier.

Publications

Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature 627 (8004) (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature 627 (8004) (2024)
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A Flavell, Zhan Ju Liu, Ming-Song Li, Wen Pan, Shu Zhu
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells. Nature communications 15 (1) (2024)
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A Flavell, Zhan Ju Liu, Ming-Song Li, Wen Pan, Shu Zhu
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells. Nature communications 15 (1) (2024)
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A Flavell, Zhan Ju Liu, Ming-Song Li, Wen Pan, Shu Zhu
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells. Nature communications 15 (1) (2024)
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Isabelle Cendali, Emily L Giddings, Catherine Pham-Danis, Michael C Yarnell, Amanda J Novak, Tonya M Brunetti, Scott B Thompson, Jorge Henao-Mejia, Richard A Flavell, Angelo D'Alessandro, M Eric Kohler, Mercedes Rincón
Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8 + T cell adoptive therapies in pre-clinical studies. Nature communications 15 (1) (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature 627 (8004) (2024)
Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A Flavell, Zhan Ju Liu, Ming-Song Li, Wen Pan, Shu Zhu
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells. Nature communications 15 (1) (2024)
Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature 627 (8004) (2024)
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A Flavell, Zhan Ju Liu, Ming-Song Li, Wen Pan, Shu Zhu
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells. Nature communications 15 (1) (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature 627 (8004) (2024)
Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Alejandro Marin-Lopez, John D Huck, Allen T Esterly, Veronica Azcutia, Connor E Rosen, Rolando García Milian, Esen Sefik, Gemma Vidal-Pedrola, Hamidah Raduwan, Tse-Yu Chen, Gunjan Arora, Stephanie Halene, Albert C Shaw, Noah W Palm, Richard A Flavell, Charles A Parkos, Saravanan Thangamani, Aaron M Ring, Erol Fikrig
The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity. Science immunology 9 (98) (2024)
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Isabelle Cendali, Emily L Giddings, Catherine Pham-Danis, Michael C Yarnell, Amanda J Novak, Tonya M Brunetti, Scott B Thompson, Jorge Henao-Mejia, Richard A Flavell, Angelo D'Alessandro, M Eric Kohler, Mercedes Rincón
Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8 + T cell adoptive therapies in pre-clinical studies. Nature communications 15 (1) (2024)
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Isabelle Cendali, Emily L Giddings, Catherine Pham-Danis, Michael C Yarnell, Amanda J Novak, Tonya M Brunetti, Scott B Thompson, Jorge Henao-Mejia, Richard A Flavell, Angelo D'Alessandro, M Eric Kohler, Mercedes Rincón
Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8 + T cell adoptive therapies in pre-clinical studies. Nature communications 15 (1) (2024)
Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature (2024)
Holly R Steach, Autumn G York, Mathias H Skadow, Shuting Chen, Jun Zhao, Kevin J Williams, Quan Zhou, Weu-Yuan Hsieh, J Richard Brewer, Rihao Qu, Justin A Shyer, Christian Harman, Esen Sefik, Walter K Mowell, Will Bailis, Can Cui, Yuval Kluger, Steven J Bensinger, Joe Craft, Richard A Flavell
IL-4 Licenses B Cell Activation Through Cholesterol Synthesis. bioRxiv : the preprint server for biology (2024)
Autumn G York, Mathias H Skadow, Joonseok Oh, Rihao Qu, Quan D Zhou, Wei-Yuan Hsieh, Walter K Mowel, J Richard Brewer, Eleanna Kaffe, Kevin J Williams, Yuval Kluger, Stephen T Smale, Jason M Crawford, Steven J Bensinger, Richard A Flavell
IL-10 constrains sphingolipid metabolism to limit inflammation. Nature 627 (8004) (2024)
Rihao Qu, Xiuyuan Cheng, Esen Sefik, Jay S Stanley Iii, Boris Landa, Francesco Strino, Sarah Platt, James Garritano, Ian D Odell, Ronald Coifman, Richard A Flavell, Peggy Myung, Yuval Kluger
Gene trajectory inference for single-cell data by optimal transport metrics. Nature biotechnology (2024)
Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Ming-Song Li, Richard A Flavell, Shu Zhu
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes. Science advances 9 (5) (2023)
Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Ming-Song Li, Richard A Flavell, Shu Zhu
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes. Science advances 9 (5) (2023)
Chenbo Ding, Zhibin Yu, Esen Sefik, Jing Zhou, Eleanna Kaffe, Gaoyang Wang, Bin Li, Richard A Flavell, Weiguo Hu, Youqiong Ye, Hua-Bing Li
A T reg -specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver. Nature aging (2023)
Danping Zheng, Gayatree Mohapatra, Lara Kern, Yiming He, Merav D Shmueli, Rafael Valdés-Mas, Aleksandra A Kolodziejczyk, Tomasz Próchnicki, Matilde B Vasconcelos, Lena Schorr, Franziska Hertel, Ye Seul Lee, Miguel Camacho Rufino, Emmanuelle Ceddaha, Sandy Shimshy, Ryan James Hodgetts, Mally Dori-Bachash, Christian Kleimeyer, Kim Goldenberg, Melina Heinemann, Noa Stettner, Alon Harmelin, Hagit Shapiro, Jens Puschhof, Minhu Chen, Richard A Flavell, Eicke Latz, Yifat Merbl, Suhaib K Abdeen, Eran Elinav
Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation. Nature immunology (2023)
Wenzhi Song, Gina M Sanchez, Daniel P Mayer, Holly N Blackburn, Irene Chernova, Richard A Flavell, Jason S Weinstein, Joseph E Craft
Cutting Edge: IL-21 and Tissue-Specific Signals Instruct Tbet+CD11c+ B Cell Development following Viral Infection. Journal of immunology (Baltimore, Md. : 1950) (2023)
Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Ming-Song Li, Richard A Flavell, Shu Zhu
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes. Science advances 9 (5) (2023)
Zheng Wei, Joonseok Oh, Richard A Flavell, Jason M Crawford
Author Correction: LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages. Nature (2023)
Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Ming-Song Li, Richard A Flavell, Shu Zhu
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes. Science advances 9 (5) (2023)
Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Ming-Song Li, Richard A Flavell, Shu Zhu
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes. Science advances 9 (5) (2023)
Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Ming-Song Li, Richard A Flavell, Shu Zhu
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes. Science advances 9 (5) (2023)
Michael Chiorazzi, Jan Martinek, Bradley Krasnick, Yunjiang Zheng, Keenan J Robbins, Rihao Qu, Gabriel Kaufmann, Zachary Skidmore, Melani Juric, Laura A Henze, Frederic Brösecke, Adam Adonyi, Jun Zhao, Liang Shan, Esen Sefik, Jacqueline Mudd, Ye Bi, S Peter Goedegebuure, Malachi Griffith, Obi Griffith, Abimbola Oyedeji, Sofia Fertuzinhos, Rolando Garcia-Milian, Daniel Boffa, Frank Detterbeck, Andrew Dhanasopon, Justin Blasberg, Benjamin Judson, Scott Gettinger, Katerina Politi, Yuval Kluger, Karolina Palucka, Ryan C Fields, Richard A Flavell
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment. Journal for immunotherapy of cancer 11 (7) (2023)
Hongdi Ma, Taidou Hu, Wanyin Tao, Jiyu Tong, Zili Han, Dietmar Herndler-Brandstetter, Zheng Wei, Ruize Liu, Tingyue Zhou, Qiuyuan Liu, Xuemei Xu, Kaiguang Zhang, Rongbin Zhou, Judy H Cho, Hua-Bing Li, Hailiang Huang, Richard A Flavell, Shu Zhu
A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis. Cell research (2023)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
George C Linderman, Jun Zhao, Manolis Roulis, Piotr Bielecki, Richard A Flavell, Boaz Nadler, Yuval Kluger
Zero-preserving imputation of single-cell RNA-seq data. Nature communications 13 (1) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation 30 (2) (2022)
Rana Gbyli, Yuan-Bin Song, Wei Liu, Yimeng Gao, Giulia Biancon, Namrata S Chandhok, Xiaman Wang, Xiaoying Fu, Amisha Patel, Ranjini Sundaram, Toma Tebaldi, Padmavathi Mamillapalli, Amer M Zeidan, Richard A Flavell, Thomas Prebet, Ranjit S Bindra, Stephanie Halene
In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2. Leukemia 36 (5) (2022)
Esen Sefik, Rihao Qu, Caroline Junqueira, Eleanna Kaffe, Haris Mirza, Jun Zhao, J Richard Brewer, Ailin Han, Holly R Steach, Benjamin Israelow, Holly N Blackburn, Sofia E Velazquez, Y Grace Chen, Stephanie Halene, Akiko Iwasak, Eric Meffre, Michel C Nussenzweig, Judy Lieberman, Craig B Wilen, Yuval Kluger, Richard A Flavell
Inflammasome activation in infected macrophages drives COVID-19 pathology. Nature 606 (7914) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Yongbo Liu, Jing Zhou, Xiaoyu Li, Xiaoting Zhang, Jintong Shi, Xuefei Wang, Hao Li, Shan Miao, Huifang Chen, Xiaoxiao He, Liting Dong, Gap Ryol Lee, Junke Zheng, Ru-Juan Liu, Bing Su, Youqiong Ye, Richard A Flavell, Chengqi Yi, Yuzhang Wu, Hua-Bing Li
tRNA-m 1 A modification promotes T cell expansion via efficient MYC protein synthesis. Nature immunology 23 (10) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation 30 (2) (2022)
Elza Evren, Emma E Ringqvist, Jean-Marc Doisne, Anna Louisa Thaller, Natalie Sleiers, Richard A Flavell, James P Di Santo, Tim Willinger
CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages. The Journal of experimental medicine 219 (2) (2022)
William E Damsky, Alice Wang, Daniel J Kim, Bryan D Young, Katelyn Singh, Michael J Murphy, Joseph Daccache, Abigale Clark, Ruveyda Ayasun, Changwan Ryu, Meaghan K McGeary, Ian D Odell, Ramesh Fazzone-Chettiar, Darko Pucar, Robert J Homer, Mridu Gulati, Edward J Miller, Marcus W Bosenberg, Richard A Flavell, Brett A King
Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis. Nature communications 13 (1) (2022)
Xian Zhang, Songyuan Luo, Minjie Wang, Qiongqiong Cao, Zhixin Zhang, Qin Huang, Jie Li, Zhiyong Deng, Tianxiao Liu, Cong-Lin Liu, Mathilde Meppen, Amélie Vromman, Richard A Flavell, Gökhan S Hotamışlıgil, Jian Liu, Peter Libby, Zhang-Suo Liu, Guo Ping Shi
Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation. Nature communications 13 (1) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation (2022)
Benjamin J Ulrich, Rakshin Kharwadkar, Michelle L Niese, Abigail Pajulas, Charanya Muralidharan, Byung-Hee Koh, Yongyao Fu, Hongyu Gao, Tristan A Hayes, Hong-Ming Zhou, Nicholas P Goplen, Andrew S Nelson, Yunlong Liu, Amelia K Linnemann, Matthew J Turner, Paula Licona-Limón, Richard A Flavell, Jie Sun, Mark H Kaplan
Allergic airway recall responses require IL-9 from resident memory CD4 + T cells. Science immunology 7 (69) (2022)
Zheng Wei, Joonseok Oh, Richard A Flavell, Jason M Crawford
LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages. Nature 609 (7926) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation 30 (2) (2022)
Yongyao Fu, Jocelyn Wang, Baohua Zhou, Abigail Pajulas, Hongyu Gao, Baskar Ramdas, Byung-Hee Koh, Benjamin J Ulrich, Shuangshuang Yang, Reuben Kapur, Jean-Christophe Renauld, Sophie Paczesny, Yunlong Liu, Robert M Tighe, Paula Licona-Limón, Richard A Flavell, Shogo Takatsuka, Daisuke Kitamura, Robert S Tepper, Jie Sun, Mark H Kaplan
An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment. Science immunology 7 (68) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation 30 (2) (2022)
Ting Zhang, Chenbo Ding, Huifang Chen, Jun Zhao, Zhejun Chen, Baiwen Chen, Kaiqiong Mao, Yajuan Hao, Manolis Roulis, Hao Xu, Yuval Kluger, Qiang Zou, Youqiong Ye, Meixiao Zhan, Richard A Flavell, Hua-Bing Li
m 6 A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB-mediated antiapoptotic pathway. Science advances 8 (12) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation (2022)
Anmin Wang, Wanyiin Tao, Jiyu Tong, Juanzi Gao, Jinghao Wang, Gaopeng Hou, Chen Qian, Guorong Zhang, Runzhi Li, Decai Wang, Xingxing Ren, Kaiguang Zhang, Siyuan Ding, Richard A Flavell, Huabing Li, Wen Pan, Shu Zhu
m6A modifications regulate intestinal immunity and rotavirus infection. eLife 11 (2022)
Tarun Tyagi, Kanika Jain, Timur O Yarovinsky, Michael Chiorazzi, Jing Du, Cecilia Castro, Julian Leether Griffin, Asawari Korde, Kathleen A Martin, Shervin S Takyar, Richard A Flavell, Abhijit A Patel, John Hwa
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells. The Journal of experimental medicine 220 (1) (2022)
Ian D Odell, Holly R Steach, Stephen B Gauld, Lauren Reinke-Breen, Jozsef Karman, Tracy L Carr, Joseph B Wetter, Lucy Phillips, Monique Hinchcliff, Richard A Flavell
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis. Science immunology 7 (78) (2022)
Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S Duncan, Chunxing Zheng, Christoph Göbl, Kyle T Gill, Jillian Haight, Andrew C Wakeham, Bryan E Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E Saunders, Richard A Flavell, Tak Wah Mak
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell death and differentiation 30 (2) (2022)
Suyavaran Arumugam, Yanqin Qin, Ziwen Liang, Sheng-Na Han, S L Tejaswi Boodapati, Junzi Li, Qiuxia Lu, Richard A Flavell, Wajahat Z Mehal, Xinshou Ouyang
GSK3β mediates the spatiotemporal dynamics of NLRP3 inflammasome activation. Cell death and differentiation 29 (10) (2022)
Yongyao Fu, Abigail Pajulas, Jocelyn Wang, Baohua Zhou, Anthony Cannon, Cherry Cheuk Lam Cheung, Jilu Zhang, Huaxin Zhou, Amanda Jo Fisher, David T Omstead, Sabrina Khan, Lei Han, Jean-Christophe Renauld, Sophie Paczesny, Hongyu Gao, Yunlong Liu, Lei Yang, Robert M Tighe, Paula Licona-Limón, Richard A Flavell, Shogo Takatsuka, Daisuke Kitamura, Jie Sun, Basar Bilgicer, Catherine R Sears, Kai Yang, Mark H Kaplan
Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9. Nature communications 13 (1) (2022)
Meng Guo, Wanyin Tao, Richard A Flavell, Shu Zhu
Potential intestinal infection and faecal-oral transmission of SARS-CoV-2. Nature reviews. Gastroenterology & hepatology 18 (4) (2021)
Qian Wang, Dehai Li, Guangchao Cao, Qiping Shi, Jing Zhu, Mingyue Zhang, Hao Cheng, Qiong Wen, Hao Xu, Leqing Zhu, Hua Zhang, Rachel J Perry, Olga Spadaro, Yunfan Yang, Shengqi He, Yong Chen, Baocheng Wang, Guangqiang Li, Zonghua Liu, Caixian Yang, Xiaoli Wu, Libing Zhou, Qinghua Zhou, Zhenyu Ju, Hongyun Lu, Yongjie Xin, Xiaoyong Yang, Cunchuan Wang, Yong Liu, Gerald I Shulman, Vishwa Deep Dixit, Ligong Lu, Hengwen Yang, Richard A Flavell, Zhinan Yin
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure. Nature 600 (7888) (2021)
Yalan Zhang, Luis Varela, Klara Szigeti-Buck, Adam Williams, Milan Stoiljkovic, Matija Sestan-Pesa, Jorge Henao-Mejia, Pasquale D Acunzo, Efrat Levy, Richard A Flavell, Tamas L Horvath, Leonard K Kaczmarek
Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1. Nature communications 12 (1) (2021)
Rakesh Verma, Andrew R Branagan, Mina L Xu, Richard A Flavell, Kavita M Dhodapkar, Madhav V Dhodapkar
Role of MBD3-SOX2 axis in residual myeloma following pomalidomide. Leukemia 35 (11) (2021)
Meng Guo, Wanyin Tao, Richard A Flavell, Shu Zhu
Reply to: Rectally shed SARS-CoV-2 lacks infectivity: time to rethink faecal-oral transmission? Nature reviews. Gastroenterology & hepatology 18 (9) (2021)
Chenqi Xu, Hua-Bing Li, Richard A Flavell
A special collection of reviews on frontiers in immunology. Cell research 30 (10) (2021)
Jing Zhou, Xingli Zhang, Jiajia Hu, Rihao Qu, Zhibin Yu, Hao Xu, Huifang Chen, Lichong Yan, Chenbo Ding, Qiang Zou, Youqiong Ye, Zhengting Wang, Richard A Flavell, Hua-Bing Li
m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity. Science advances 7 (25) (2021)
Ningbo Wu, Hongxiang Sun, Xiaoyun Zhao, Yao Zhang, Jianmei Tan, Yuanyuan Qi, Qun Wang, Melissa Shu Feng Ng, Zhaoyuan Liu, Lingjuan He, Xiaoyin Niu, Lei Chen, Zhiduo Liu, Hua-Bing Li, Yi Arial Zeng, Manolis Roulis, Dou Liu, Jinke Cheng, Bin Zhou, Lai Guan Ng, Duowu Zou, Youqiong Ye, Richard A Flavell, Florent Ginhoux, Bing Su
MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche. Nature 592 (7855) (2021)
Hao Song, Jiaxi Song, Ming Cheng, Meijuan Zheng, Tian Wang, Sha Tian, Richard A Flavell, Shu Zhu, Hua-Bing Li, Chen Ding, Haiming Wei, Rui Sun, Hui Peng, Zhigang Tian
METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells. Nature communications 12 (1) (2021)
Esen Sefik, Benjamin Israelow, Haris Mirza, Jun Zhao, Rihao Qu, Eleanna Kaffe, Eric Song, Stephanie Halene, Eric Meffre, Yuval Kluger, Michel C Nussenzweig, Craig B Wilen, Akiko Iwasak, Richard A Flavell
A humanized mouse model of chronic COVID-19. Nature biotechnology 40 (6) (2021)
Yuan-Bin Song, Liang Shan, Rana Gbyli, Wei Liu, Till Strowig, Amisha Patel, Xiaoying Fu, Xiaman Wang, Mina L Xu, Yimeng Gao, Ashley Qin, Emanuela M Bruscia, Toma Tebaldi, Giulia Biancon, Padmavathi Mamillapalli, David Urbonas, Elizabeth Eynon, David G Gonzalez, Jie Chen, Diane S Krause, Jonathan Alderman, Stephanie Halene, Richard A Flavell
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells. Science (New York, N.Y.) 371 (6533) (2021)
Esen Sefik, Ben Israelow, Jun Zhao, Rihao Qu, Eric Song, Haris Mirza, Eleanna Kaffe, Stephanie Halene, Eric Meffre, Yuval Kluger, Michel C Nussenzweig, Craig B Wilen, Akiko Iwasak, Richard A Flavell
A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options. Research square (2021)
Esen Sefik, Rihao Qu, Eleanna Kaffe, Jun Zhao, Caroline Junqueira, Haris Mirza, Ricky Brewer, Ailin Han, Holly R Steach, Benjamin Israelow, Y Grace Chen, Stephanie Halene, Akiko Iwasak, Eric Meffre, Michel Nussenzweig, Judy Lieberman, Craig B Wilen, Yuval Kluger, Richard A Flavell
Viral replication in human macrophages enhances an inflammatory cascade and interferon driven chronic COVID-19 in humanized mice. bioRxiv : the preprint server for biology (2021)
Piotr Bielecki, Samantha J Riesenfeld, Jan-Christian Hütter, Elena Torlai Triglia, Monika S Kowalczyk, Roberto R Ricardo-Gonzalez, Mi Lian, Maria C Amezcua Vesely, Lina Kroehling, Hao Xu, Michal Slyper, Christoph Muus, Leif S Ludwig, Elena Christian, Liming Tao, Amanda J Kedaigle, Holly R Steach, Autumn G York, Mathias H Skadow, Parastou Yaghoubi, Danielle Dionne, Abigail Jarret, Heather M McGee, Caroline B M Porter, Paula Licona-Limón, Will Bailis, Ruaidhrí Jackson, Nicola Gagliani, Georg Gasteiger, Richard M Locksley, Aviv Regev, Richard A Flavell
Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature 592 (7852) (2021)
Rakshin Kharwadkar, Benjamin J Ulrich, Amina Abdul Qayum, Byunghee Koh, Paula Licona-Limón, Richard A Flavell, Mark H Kaplan
Expression Efficiency of Multiple Il9 Reporter Alleles Is Determined by Cell Lineage. ImmunoHorizons 4 (5) (2020)
Jing Wang, Richard A Flavell, Hua-Bing Li
Antiviral immunity: a link to bile acids. Cell research 29 (3) (2020)
Ting Zhou, William Damsky, Orr-El Weizman, Meaghan K McGeary, K Patricia Hartmann, Connor E Rosen, Suzanne Fischer, Ruaidhri Jackson, Richard A Flavell, Jun Wang, Miguel F Sanmamed, Marcus W Bosenberg, Aaron M Ring
IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy. Nature 583 (7817) (2020)
Laura Garcia Perez, Jan Kempski, Heather M McGee, Penelope Pelzcar, Theodora Agalioti, Anastasios Giannou, Leonie Konczalla, Leonie Brockmann, Ramez Wahib, Hao Xu, Maria Carolina Amezcua Vesely, Shiwa Soukou, Babett Steglich, Tanja Bedke, Carolin Manthey, Oliver Seiz, Björn-Philipp Diercks, Stylianos Gnafakis, Andreas H Guse, Daniel Perez, Jakob R Izbicki, Nicola Gagliani, Richard A Flavell, Samuel Huber
TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer. Nature communications 11 (1) (2020)
Hao Xu, Theodora Agalioti, Jun Zhao, Babett Steglich, Ramez Wahib, Maria Carolina Amezcua Vesely, Piotr Bielecki, Will Bailis, Ruaidhri Jackson, Daniel Perez, Jakob Izbicki, Paula Licona-Limón, Vesa Kaartinen, Jens Geginat, Enric Esplugues, Eva Tolosa, Samuel Huber, Richard A Flavell, Nicola Gagliani
The induction and function of the anti-inflammatory fate of TH17 cells. Nature communications 11 (1) (2020)
Hyun Bong Park, Zheng Wei, Joonseok Oh, Hao Xu, Chung Sub Kim, Rurun Wang, Thomas P Wyche, Grazia Piizzi, Richard A Flavell, Jason M Crawford
Sulfamethoxazole drug stress upregulates antioxidant immunomodulatory metabolites in Escherichia coli. Nature microbiology 5 (11) (2020)
Manolis Roulis, Aimilios Kaklamanos, Marina Schernthanner, Piotr Bielecki, Jun Zhao, Eleanna Kaffe, Laura-Sophie Frommelt, Rihao Qu, Marlene S Knapp, Ana Henriques, Niki Chalkidi, Vasiliki Koliaraki, Jing Jiao, J Richard Brewer, Maren Bacher, Holly N Blackburn, Xiaoyun Zhao, Richard M Breyer, Vassilis Aidinis, Dhanpat Jain, Bing Su, Harvey R Herschman, Yuval Kluger, George Kollias, Richard A Flavell
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature 580 (7804) (2020)
Laura Garcia Perez, Jan Kempski, Heather M McGee, Penelope Pelzcar, Theodora Agalioti, Anastasios Giannou, Leonie Konczalla, Leonie Brockmann, Ramez Wahib, Hao Xu, Maria Carolina Amezcua Vesely, Shiwa Soukou, Babett Steglich, Tanja Bedke, Carolin Manthey, Oliver Seiz, Björn-Philipp Diercks, Stylianos Gnafakis, Andreas H Guse, Daniel Perez, Jakob R Izbicki, Nicola Gagliani, Richard A Flavell, Samuel Huber
Publisher Correction: TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer. Nature communications 11 (1) (2020)
Soo Seok Hwang, Jaechul Lim, Zhibin Yu, Philip Kong, Esen Sefik, Hao Xu, Christian C D Harman, Lark Kyun Kim, Gap Ryol Lee, Hua-Bing Li, Richard A Flavell
mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence. Science (New York, N.Y.) 367 (6483) (2020)
Yuanyuan Duan, Guangqiang Li, Miaomiao Xu, Xiaofei Qi, Mingxia Deng, Xuejia Lin, Zhiwei Lei, Yi Hu, Zhenghu Jia, Quanli Yang, Guangchao Cao, Zonghua Liu, Qiong Wen, Zhenhua Li, Jie Tang, Wei Kevin Zhang, Pingbo Huang, Limin Zheng, Richard A Flavell, Jianlei Hao, Zhinan Yin
CFTR is a negative regulator of γδ T cell IFN-γ production and antitumor immunity. Cellular & molecular immunology 18 (8) (2020)
Quanli Yang, Xia Liu, Qihui Liu, Zerong Guan, Jing Luo, Guangchao Cao, Ruitian Cai, Zhenhua Li, Yan Xu, Zengfeng Wu, Miaomiao Xu, Song Zhang, Fan Zhang, Hengwen Yang, Xuejia Lin, Meixiang Yang, Yangzhe Wu, Yunfei Gao, Richard A Flavell, Jianlei Hao, Zhinan Yin
Roles of mTORC1 and mTORC2 in controlling γδ T1 and γδ T17 differentiation and function. Cell death and differentiation 27 (7) (2020)
Long Yang, Tingting Geng, Guang Yang, Jinzhu Ma, Leilei Wang, Harshada Ketkar, Duomeng Yang, Tao Lin, Jesse Hwang, Shu Zhu, Yanlin Wang, Jianfeng Dai, Fuping You, Cheng Gong, Anthony T Vella, Richard A Flavell, Erol Fikrig, Penghua Wang
Macrophage scavenger receptor 1 controls Chikungunya virus infection through autophagy in mice. Communications biology 3 (1) (2020)
Xingli Zhang, Richard A Flavell, Hua-Bing Li
hnRNPA2B1: a nuclear DNA sensor in antiviral immunity. Cell research 29 (11) (2020)
Justin A Shyer, Richard A Flavell, Will Bailis
Metabolic signaling in T cells. Cell research 30 (8) (2020)
Sandip Mukherjee, Ritesh Kumar, Elviche Tsakem Lenou, Venkatesha Basrur, Dimitris L Kontoyiannis, Fotis Ioakeimidis, George Mosialos, Arianne L Theiss, Richard A Flavell, K Venuprasad
Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation. Nature immunology 21 (6) (2020)
Felix Knauf, J Richard Brewer, Richard A Flavell
Immunity, microbiota and kidney disease. Nature reviews. Nephrology 15 (5) (2019)
Sarah R Barger, Nicholas S Reilly, Maria S Shutova, Qingsen Li, Paolo Maiuri, John M Heddleston, Mark S Mooseker, Richard A Flavell, Tatyana Svitkina, Patrick W Oakes, Mira Krendel, Nils C Gauthier
Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis. Nature communications 10 (1) (2019)
Jordan P Lewandowski, James C Lee, Taeyoung Hwang, Hongjae Sunwoo, Jill M Goldstein, Abigail F Groff, Nydia P Chang, William Mallard, Adam Williams, Jorge Henao-Meija, Richard A Flavell, Jeannie T Lee, Chiara Gerhardinger, Amy J Wagers, John L Rinn
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis. Nature communications 10 (1) (2019)
Yuan-Bin Song, Anthony Rongvaux, Ashley Taylor, Tingting Jiang, Toma Tebaldi, Kunthavai Balasubramanian, Arun Bagale, Yunus Kasim Terzi, Rana Gbyli, Xiaman Wang, Xiaoying Fu, Yimeng Gao, Jun Zhao, Nikolai A Podoltsev, Mina Xu, Natalia Neparidze, Ellice Wong, Richard Torres, Emanuela M Bruscia, Yuval Kluger, Markus Gabriel Manz, Richard A Flavell, Stephanie Halene
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies. Nature communications 10 (1) (2019)

Richard A Flavell.css-eqlu8i{font-size:small;padding-left:4px;} (Richard Flavell)

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Richard A Flavell (Richard Flavell)