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Leif S Ludwig

ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 14

Top Venues

Broad Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Broad Institute Nov 16o 2016

United States

Postdoctoral researcher

Publications

Caleb A Lareau, Sonia M Dubois, Frank A Buquicchio, Yu-Hsin Hsieh, Kopal Garg, Pauline Kautz, Lena Nitsch, Samantha D Praktiknjo, Patrick Maschmeyer, Jeffrey M Verboon, Jacob C Gutierrez, Yajie Yin, Evgenij Fiskin, Wendy Luo, Eleni P Mimitou, Christoph Muus, Rhea Malhotra, Sumit Parikh, Mark D Fleming, Lena Oevermann, Johannes Hubertus Schulte, Cornelia Eckert, Anshul Kundaje, Peter Smibert, Santosha A Vardhana, Ansuman T Satpathy, Aviv Regev, Vijay G Sankaran, Suneet Agarwal, Leif S Ludwig
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells. Nature genetics (2023)
Florian V De Rop, Gert Hulselmans, Christopher Flerin, Paula Soler-Vila, Albert Rafels, Valerie Christiaens, Carmen Bravo González-Blas, Domenica Marchese, Ginevra Caratù, Suresh Poovathingal, Orit Rozenblatt-Rosen, Michael Slyper, Wendy Luo, Christoph Muus, Fabiana M Duarte, Rojesh Shrestha, S Tansu Bagdatli, M Ryan Corces, Lira Mamanova, Andrew Knights, Kerstin B Meyer, Ryan M Mulqueen, Akram Taherinasab, Patrick Maschmeyer, Joern Pezoldt, Camille Lucie Germaine Lambert, Marta Iglesias, Sebastián R Najle, Zain Y Dossani, Luciano G Martelotto, Zachary Daniel Burkett, Ronald Lebofsky, José Ignacio Martin-Subero, Satish Pillai, Arnau Sebé-Pedrós, Bart Deplancke, Sarah A Teichmann, Leif S Ludwig, Theodore P Braun, Andrew C Adey, William J Greenleaf, Jason D Buenrostro, Aviv Regev, Stein Aerts, Holger Heyn
Systematic benchmarking of single-cell ATAC-sequencing protocols. Nature biotechnology (2023)
Caleb A Lareau, Leif S Ludwig, Christoph Muus, Satyen H Gohil, Tongtong Zhao, Zachary Chiang, Karin Pelka, Jeffrey M Verboon, Wendy Luo, Elena Christian, Daniel Rosebrock, Gad A Getz, Genevieve M Boland, Fei Chen, Jason D Buenrostro, Nir Hacohen, Catherine J Wu, Martin J Aryee, Aviv Regev, Vijay G Sankaran
Author Correction: Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nature biotechnology (2023)
Caleb A Lareau, Vincent Liu, Christoph Muus, Samantha D Praktiknjo, Lena Nitsch, Pauline Kautz, Katalin D Sandor, Yajie Yin, Jacob C Gutierrez, Karin Pelka, Ansuman T Satpathy, Aviv Regev, Vijay G Sankaran, Leif S Ludwig
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility. Nature protocols (2023)
Leif S Ludwig, Caleb A Lareau, Erik L Bao, Nan Liu, Taiju Utsugisawa, Alex M Tseng, Samuel A Myers, Jeffrey M Verboon, Jacob C Ulirsch, Wendy Luo, Christoph Muus, Claudia Fiorini, Meagan E Olive, Christopher M Vockley, Mathias Munschauer, Abigail Hunter, Hiromi Ogura, Toshiyuki Yamamoto, Hiroko Inada, Shinichiro Nakagawa, Shuichi Ozono, Vidya Subramanian, Roberto Chiarle, Bertil Glader, Steven A Carr, Martin J Aryee, Anshul Kundaje, Stuart H Orkin, Aviv Regev, Timothy L McCavit, Hitoshi Kanno, Vijay G Sankaran
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1. Blood 139 (16) (2022)
Livius Penter, Elisa Ten Hacken, Jackson Southard, Caleb A Lareau, Leif S Ludwig, Shuqiang Li, Donna S Neuberg, Kenneth J Livak, Catherine J Wu
Mitochondrial DNA mutations as natural barcodes for lineage tracing of murine tumor models. Cancer research (2022)
Tyler E Miller, Caleb A Lareau, Julia A Verga, Erica A K DePasquale, Vincent Liu, Daniel Ssozi, Katalin D Sandor, Yajie Yin, Leif S Ludwig, Chadi A El Farran, Duncan M Morgan, Ansuman T Satpathy, Gabriel K Griffin, Andrew A Lane, John Christopher Love, Bradley E Bernstein, Vijay G Sankaran, Peter van Galen
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations. Nature biotechnology 40 (7) (2022)
Evgenij Fiskin, Caleb A Lareau, Leif S Ludwig, Gökçen Eraslan, Feimei Liu, Aaron M Ring, Ramnik J Xavier, Aviv Regev
Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC. Nature biotechnology (2021)
Eleni P Mimitou, Caleb A Lareau, Kelvin Y Chen, Andre L Zorzetto-Fernandes, Yuhan Hao, Yusuke Takeshima, Wendy Luo, Tse-Shun Huang, Bertrand Z Yeung, Efthymia Papalexi, Pratiksha I Thakore, Tatsuya Kibayashi, James Badger Wing, Mayu Hata, Rahul Satija, Kristopher L Nazor, Shimon Sakaguchi, Leif S Ludwig, Vijay G Sankaran, Aviv Regev, Peter Smibert
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells. Nature biotechnology 39 (10) (2021)
Novalia Pishesha, Thibault Harmand, Liyan Y Smeding, Weiyi Ma, Leif S Ludwig, Robine Janssen, Ashraful Islam, Yushu J Xie, Tao Fang, Nicholas McCaul, William Pinney, Harun R Sugito, Martin A Rossotti, Gualberto Gonzalez-Sapienza, Hidde L Ploegh
Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes. Nature biomedical engineering 5 (11) (2021)
Meifang Qi, Utthara Nayar, Leif S Ludwig, Nikhil Wagle, Esther Rheinbay
cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries. BMC bioinformatics 22 (1) (2021)
Piotr Bielecki, Samantha J Riesenfeld, Jan-Christian Hütter, Elena Torlai Triglia, Monika S Kowalczyk, Roberto R Ricardo-Gonzalez, Mi Lian, Maria C Amezcua Vesely, Lina Kroehling, Hao Xu, Michal Slyper, Christoph Muus, Leif S Ludwig, Elena Christian, Liming Tao, Amanda J Kedaigle, Holly R Steach, Autumn G York, Mathias H Skadow, Parastou Yaghoubi, Danielle Dionne, Abigail Jarret, Heather M McGee, Caroline B M Porter, Paula Licona-Limón, Will Bailis, Ruaidhrí Jackson, Nicola Gagliani, Georg Gasteiger, Richard M Locksley, Aviv Regev, Richard A Flavell
Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature 592 (7852) (2021)
Caleb A Lareau, Leif S Ludwig, Christoph Muus, Satyen H Gohil, Tongtong Zhao, Zachary Chiang, Karin Pelka, Jeffrey M Verboon, Wendy Luo, Elena Christian, Daniel Rosebrock, Gad A Getz, Genevieve M Boland, Fei Chen, Jason D Buenrostro, Nir Hacohen, Catherine J Wu, Martin J Aryee, Aviv Regev, Vijay G Sankaran
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nature biotechnology 39 (4) (2020)
Nour J Abdulhay, Claudia Fiorini, Jeffrey M Verboon, Leif S Ludwig, Jacob C Ulirsch, Barbara Zieger, Caleb A Lareau, Xiaoli Mi, Anindita Roy, Esther A Obeng, Miriam Erlacher, Namrata Gupta, Stacey B Gabriel, Benjamin L Ebert, Charlotte M Niemeyer, Rami N Khoriaty, Philip Ancliff, Hanna T Gazda, Marcin W Wlodarski, Vijay G Sankaran
Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation. The Journal of experimental medicine 216 (5) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Leif S Ludwig