Leif S Ludwig

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 17

Top Venues

Nature biotechnology

Clinical hematology international

BMC bioinformatics

Nature protocols

Broad Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Broad Institute Nov 16 2016

United States

Postdoctoral researcher

Whitehead Institute for Biomedical Research Mar 01 2011 - Dec 31 2014

United States

Graduate student :: Laboratory of Harvey Lodish

Deutsches Rheuma-Forschungszentrum Berlin Oct 01 2007 - Feb 15 2011

Germany

Diploma student and student research assistant :: Laboratories of Alf Hamann & Jochen Hühn

Publications

Livius Penter, Nicoletta Cieri, Katie Maurer, Marwan Kwok, Haoxiang Lyu, Wesley S Lu, Giacomo Oliveira, Satyen H Gohil, Ignaty Leshchiner, Caleb A Lareau, Leif S Ludwig, Donna S Neuberg, Haesook T Kim, Shuqiang Li, Lars Bullinger, Jerome Ritz, Gad A Getz, Jacqueline S Garcia, Robert J Soiffer, Kenneth J Livak, Catherine J Wu
Tracking rare single donor and recipient immune and leukemia cells after allogeneic hematopoietic cell transplantation using mitochondrial DNA mutations. Blood cancer discovery (2024)
Anja C Rathgeber, Leif S Ludwig, Livius Penter
Single-cell genomics-based immune and disease monitoring in blood malignancies. Clinical hematology international 6 (2) (2024)
Anja C Rathgeber, Leif S Ludwig, Livius Penter
Single-cell genomics-based immune and disease monitoring in blood malignancies. Clinical hematology international 6 (2) (2024)
Caleb A Lareau, Sonia M Dubois, Frank A Buquicchio, Yu-Hsin Hsieh, Kopal Garg, Pauline Kautz, Lena Nitsch, Samantha D Praktiknjo, Patrick Maschmeyer, Jeffrey M Verboon, Jacob C Gutierrez, Yajie Yin, Evgenij Fiskin, Wendy Luo, Eleni P Mimitou, Christoph Muus, Rhea Malhotra, Sumit Parikh, Mark Daniel Fleming, Lena Oevermann, Johannes Hubertus Schulte, Cornelia Eckert, Anshul Kundaje, Peter Smibert, Santosha A Vardhana, Ansuman T Satpathy, Aviv Regev, Vijay G Sankaran, Suneet Agarwal, Leif S Ludwig
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells. Nature genetics (2023)
Florian V De Rop, Gert Hulselmans, Christopher Flerin, Paula Soler-Vila, Albert Rafels, Valerie Christiaens, Carmen Bravo González-Blas, Domenica Marchese, Ginevra Caratù, Suresh Poovathingal, Orit Rozenblatt-Rosen, Michael Slyper, Wendy Luo, Christoph Muus, Fabiana M Duarte, Rojesh Shrestha, S Tansu Bagdatli, M Ryan Corces, Lira Mamanova, Andrew Knights, Kerstin B Meyer, Ryan M Mulqueen, Akram Taherinasab, Patrick Maschmeyer, Joern Pezoldt, Camille Lucie Germaine Lambert, Marta Iglesias, Sebastián R Najle, Zain Y Dossani, Luciano G Martelotto, Zachary Daniel Burkett, Ronald Lebofsky, José Ignacio Martin-Subero, Satish Pillai, Arnau Sebé-Pedrós, Bart Deplancke, Sarah A Teichmann, Leif S Ludwig, Theodore P Braun, Andrew C Adey, William J Greenleaf, Jason D Buenrostro, Aviv Regev, Stein Aerts, Holger Heyn
Systematic benchmarking of single-cell ATAC-sequencing protocols. Nature biotechnology (2023)
Caleb A Lareau, Leif S Ludwig, Christoph Muus, Satyen H Gohil, Tongtong Zhao, Zachary Chiang, Karin Pelka, Jeffrey M Verboon, Wendy Luo, Elena Christian, Daniel Rosebrock, Gad A Getz, Genevieve M Boland, Fei Chen, Jason D Buenrostro, Nir Hacohen, Catherine J Wu, Martin J Aryee, Aviv Regev, Vijay G Sankaran
Author Correction: Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nature biotechnology (2023)
Caleb A Lareau, Vincent Liu, Christoph Muus, Samantha D Praktiknjo, Lena Nitsch, Pauline Kautz, Katalin D Sandor, Yajie Yin, Jacob C Gutierrez, Karin Pelka, Ansuman T Satpathy, Aviv Regev, Vijay G Sankaran, Leif S Ludwig
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility. Nature protocols (2023)
Leif S Ludwig, Caleb A Lareau, Erik L Bao, Nan Liu, Taiju Utsugisawa, Alex M Tseng, Samuel A Myers, Jeffrey M Verboon, Jacob C Ulirsch, Wendy Luo, Christoph Muus, Claudia Fiorini, Meagan E Olive, Christopher M Vockley, Mathias Munschauer, Abigail Hunter, Hiromi Ogura, Toshiyuki Yamamoto, Hiroko Inada, Shinichiro Nakagawa, Shuichi Ozono, Vidya Subramanian, Roberto Chiarle, Bertil Glader, Steven A Carr, Martin J Aryee, Anshul Kundaje, Stuart H Orkin, Aviv Regev, Timothy L McCavit, Hitoshi Kanno, Vijay G Sankaran
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1. Blood 139 (16) (2022)
Livius Penter, Elisa Ten Hacken, Jackson Southard, Caleb A Lareau, Leif S Ludwig, Shuqiang Li, Donna S Neuberg, Kenneth J Livak, Catherine J Wu
Mitochondrial DNA mutations as natural barcodes for lineage tracing of murine tumor models. Cancer research (2022)
Tyler E Miller, Caleb A Lareau, Julia A Verga, Erica A K DePasquale, Vincent Liu, Daniel Ssozi, Katalin D Sandor, Yajie Yin, Leif S Ludwig, Chadi A El Farran, Duncan M Morgan, Ansuman T Satpathy, Gabriel K Griffin, Andrew A Lane, John Christopher Love, Bradley E Bernstein, Vijay G Sankaran, Peter van Galen
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations. Nature biotechnology 40 (7) (2022)
Evgenij Fiskin, Caleb A Lareau, Leif S Ludwig, Gökçen Eraslan, Feimei Liu, Aaron M Ring, Ramnik J Xavier, Aviv Regev
Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC. Nature biotechnology (2021)
Eleni P Mimitou, Caleb A Lareau, Kelvin Y Chen, Andre L Zorzetto-Fernandes, Yuhan Hao, Yusuke Takeshima, Wendy Luo, Tse-Shun Huang, Bertrand Z Yeung, Efthymia Papalexi, Pratiksha I Thakore, Tatsuya Kibayashi, James Badger Wing, Mayu Hata, Rahul Satija, Kristopher L Nazor, Shimon Sakaguchi, Leif S Ludwig, Vijay G Sankaran, Aviv Regev, Peter Smibert
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells. Nature biotechnology 39 (10) (2021)
Novalia Pishesha, Thibault Harmand, Liyan Y Smeding, Weiyi Ma, Leif S Ludwig, Robine Janssen, Ashraful Islam, Yushu J Xie, Tao Fang, Nicholas McCaul, William Pinney, Harun R Sugito, Martin A Rossotti, Gualberto Gonzalez-Sapienza, Hidde L Ploegh
Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes. Nature biomedical engineering 5 (11) (2021)
Meifang Qi, Utthara Nayar, Leif S Ludwig, Nikhil Wagle, Esther Rheinbay
cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries. BMC bioinformatics 22 (1) (2021)
Piotr Bielecki, Samantha J Riesenfeld, Jan-Christian Hütter, Elena Torlai Triglia, Monika S Kowalczyk, Roberto R Ricardo-Gonzalez, Mi Lian, Maria C Amezcua Vesely, Lina Kroehling, Hao Xu, Michal Slyper, Christoph Muus, Leif S Ludwig, Elena Christian, Liming Tao, Amanda J Kedaigle, Holly R Steach, Autumn G York, Mathias H Skadow, Parastou Yaghoubi, Danielle Dionne, Abigail Jarret, Heather M McGee, Caroline B M Porter, Paula Licona-Limón, Will Bailis, Ruaidhrí Jackson, Nicola Gagliani, Georg Gasteiger, Richard M Locksley, Aviv Regev, Richard A Flavell
Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature 592 (7852) (2021)
Caleb A Lareau, Leif S Ludwig, Christoph Muus, Satyen H Gohil, Tongtong Zhao, Zachary Chiang, Karin Pelka, Jeffrey M Verboon, Wendy Luo, Elena Christian, Daniel Rosebrock, Gad A Getz, Genevieve M Boland, Fei Chen, Jason D Buenrostro, Nir Hacohen, Catherine J Wu, Martin J Aryee, Aviv Regev, Vijay G Sankaran
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nature biotechnology 39 (4) (2020)
Nour J Abdulhay, Claudia Fiorini, Jeffrey M Verboon, Leif S Ludwig, Jacob C Ulirsch, Barbara Zieger, Caleb A Lareau, Xiaoli Mi, Anindita Roy, Esther A Obeng, Miriam Erlacher, Namrata Gupta, Stacey B Gabriel, Benjamin L Ebert, Charlotte M Niemeyer, Rami N Khoriaty, Philip Ancliff, Hanna T Gazda, Marcin W Wlodarski, Vijay G Sankaran
Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation. The Journal of experimental medicine 216 (5) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Leif S Ludwig