Ri-Lei Yu (Rilei Yu, RiLei Yu)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 39

Top Venues

Journal of medicinal chemistry

Marine drugs

ACS medicinal chemistry letters

ACS chemical neuroscience

Ocean University of China

University of Queensland (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Ocean University of China Oct 01 2014

China

Associate Professor :: School of medicine and pharmacy

Education History

University of Queensland Jun 13 2009 - Jan 12 2013

Australia

PHD :: Institute for molecular bioscience

Publications

Qiang Li, Linmao Ke, Dandan Yu, Han Xu, Zixuan Zhang, Ri-Lei Yu, Tao Jiang, Yue-Wei Guo, Mingzhi Su, Xin Jin
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury. Journal of medicinal chemistry 67 (4) (2024)
Xiao Li, Han-Shen Tae, Shen Chen, Arsalan Yousuf, Linhong Huang, Jinghui Zhang, Tao Jiang, David J Adams, Ri-Lei Yu
Dual Antagonism of α9α10 nAChR and GABA B Receptor-Coupled Ca V 2.2 Channels by an Analgesic αO-Conotoxin Analogue. Journal of medicinal chemistry 67 (2) (2024)
Tianmiao Li, Han-Shen Tae, Jiazhen Liang, Zixuan Zhang, Xiao Li, Tao Jiang, David J Adams, Ri-Lei Yu
Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors. Marine drugs 22 (3) (2024)
Tianmiao Li, Han-Shen Tae, Jiazhen Liang, Zixuan Zhang, Xiao Li, Tao Jiang, David J Adams, Ri-Lei Yu
Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors. Marine drugs 22 (3) (2024)
Xiao Li, Han-Shen Tae, Shen Chen, Arsalan Yousuf, Linhong Huang, Jinghui Zhang, Tao Jiang, David J Adams, Ri-Lei Yu
Dual Antagonism of α9α10 nAChR and GABA B Receptor-Coupled Ca V 2.2 Channels by an Analgesic αO-Conotoxin Analogue. Journal of medicinal chemistry (2024)
Xiao Li, Han-Shen Tae, Shen Chen, Arsalan Yousuf, Linhong Huang, Jinghui Zhang, Tao Jiang, David J Adams, Ri-Lei Yu
Dual Antagonism of α9α10 nAChR and GABA B Receptor-Coupled Ca V 2.2 Channels by an Analgesic αO-Conotoxin Analogue. Journal of medicinal chemistry 67 (2) (2024)
Qiang Li, Linmao Ke, Dandan Yu, Han Xu, Zixuan Zhang, Ri-Lei Yu, Tao Jiang, Yue-Wei Guo, Mingzhi Su, Xin Jin
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury. Journal of medicinal chemistry 67 (4) (2024)
Tianmiao Li, Han-Shen Tae, Jiazhen Liang, Zixuan Zhang, Xiao Li, Tao Jiang, David J Adams, Ri-Lei Yu
Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors. Marine drugs 22 (3) (2024)
Xiao Li, Han-Shen Tae, Shen Chen, Arsalan Yousuf, Linhong Huang, Jinghui Zhang, Tao Jiang, David J Adams, Ri-Lei Yu
Dual Antagonism of α9α10 nAChR and GABA B Receptor-Coupled Ca V 2.2 Channels by an Analgesic αO-Conotoxin Analogue. Journal of medicinal chemistry (2024)
Qiang Li, Linmao Ke, Dandan Yu, Han Xu, Zixuan Zhang, Ri-Lei Yu, Tao Jiang, Yue-Wei Guo, Mingzhi Su, Xin Jin
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury. Journal of medicinal chemistry (2024)
Yan-Yan Chu, Huanhuan Zhang, Mengke Yang, Ri-Lei Yu
Molecular Dynamic Simulations Reveal the Activation Mechanisms of Oxidation-Induced TRPV1. International journal of molecular sciences 24 (11) (2023)
Xin Jin, Tingting Qiu, Jianling Xie, Xianfeng Wei, Xuemin Wang, Ri-Lei Yu, Christopher Proud, Tao Jiang
Correction to "Using Imidazo[2,1- b ][1,3,4]thiadiazol Skeleton to Design and Synthesize Novel MNK Inhibitors". ACS medicinal chemistry letters 14 (3) (2023)
Yue Zhang, Ruijuan Yin, Hao Jiang, Chaoming Wang, Xiao Wang, Dongping Wang, Kai Zhang, Ri-Lei Yu, Xuechen Li, Tao Jiang
Peptide Stapling through Site-Directed Conjugation of Triazine Moieties to the Tyrosine Residues of a Peptide. Organic letters (2023)
Chaoming Wang, Jinman Zhang, Xianfeng Wei, Mengke Yang, Wei-Ping Ma, Ri-Lei Yu, Ming Liu, Tao Jiang
Design, Synthesis, and Biological Evaluation of Marine Lissodendrins B Analogues as Modulators of ABCB1-Mediated Multidrug Resistance. Marine drugs 21 (5) (2023)
Xin Jin, Maowei Li, Tingting Qiu, Ri-Lei Yu, Tao Jiang
Design, Synthesis and Evaluation of Novel Phorbazole C Derivatives as MNK Inhibitors through Virtual High-Throughput Screening. Marine drugs 20 (7) (2022)
Xin Jin, Tingting Qiu, Jianling Xie, Xianfeng Wei, Xuemin Wang, Ri-Lei Yu, Christopher Proud, Tao Jiang
Using Imidazo[2,1- b ][1,3,4]thiadiazol Skeleton to Design and Synthesize Novel MNK Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Xin Jin, Tingting Qiu, Jianling Xie, Xianfeng Wei, Xuemin Wang, Ri-Lei Yu, Christopher Proud, Tao Jiang
Using Imidazo[2,1- b ][1,3,4]thiadiazol Skeleton to Design and Synthesize Novel MNK Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Hongfei Jiang, Qing Zhang, Yue Zhang, Huxin Feng, Hao Jiang, Fan Pu, Ri-Lei Yu, Zheng Zhong, Chaoming Wang, Yi Man Eva Fung, Pilar Blasco, Yongxin Li, Tao Jiang, Xuechen Li
Triazine-pyridine chemistry for protein labelling on tyrosine. Chemical communications (Cambridge, England) 58 (50) (2022)
Jiazhen Liang, Han-Shen Tae, Zitong Zhao, Xiao Li, Jinghui Zhang, Shen Chen, Tao Jiang, David J Adams, Ri-Lei Yu
Mechanism of Action and Structure-Activity Relationship of α-Conotoxin Mr1.1 at the Human α9α10 Nicotinic Acetylcholine Receptor. Journal of medicinal chemistry (2022)
Xin Jin, Tingting Qiu, Jianling Xie, Xianfeng Wei, Xuemin Wang, Ri-Lei Yu, Christopher Proud, Tao Jiang
Using Imidazo[2,1- b ][1,3,4]thiadiazol Skeleton to Design and Synthesize Novel MNK Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Yuan Ma, Qiushi Cao, Mengke Yang, Yue Gao, Shuiping Fu, Wenhao Du, David J Adams, Tao Jiang, Han-Shen Tae, Ri-Lei Yu
Single-Disulfide Conopeptide Czon1107, an Allosteric Antagonist of the Human α3β4 Nicotinic Acetylcholine Receptor. Marine drugs 20 (8) (2022)
Jian-Qiang Zhang, Rui Li, Xue-Yang Dong, Na He, Rui-Juan Yin, Meng-Ke Yang, Jie-Yu Liu, Ri-Lei Yu, Chen-Yang Zhao, Tao Jiang
Design, Synthesis and Structure-Activity Relationship Studies of Meridianin Derivatives as Novel JAK/STAT3 Signaling Inhibitors. International journal of molecular sciences 23 (4) (2022)
Qiuyuan Huang, Xin Chu, Haoran Zhang, Shuo Yu, Longxiao Zhang, Xuerong Zhang, Ri-Lei Yu, Chenyun Guo, Qiuyun Dai
Discovery and Structural and Functional Characterization of a Novel A-Superfamily Conotoxin Targeting α9α10 Nicotinic Acetylcholine Receptor. ACS chemical biology 17 (9) (2022)
Xuewen Hou, Changlong Li, Runfang Zhang, Yinping Li, Huadong Li, Yundong Zhang, Han-Shen Tae, Ri-Lei Yu, Qian Che, Tianjiao Zhu, De-Hai Li, Guojian Zhang
Unusual Tetrahydropyridoindole-Containing Tetrapeptides with Human Nicotinic Acetylcholine Receptors Targeting Activity Discovered from Antarctica-Derived Psychrophilic Pseudogymnoascus sp. HDN17-933. Marine drugs 20 (10) (2022)
Ningning Wei, Yan-Yan Chu, Huijie Liu, Qingliang Xu, Tao Jiang, Ri-Lei Yu
Antagonistic Mechanism of α-Conotoxin BuIA toward the Human α3β2 Nicotinic Acetylcholine Receptor. ACS chemical neuroscience (2021)
Guangwei Wu, Guihong Yu, Yunjia Yu, Shuang Yang, Zhongwei Duan, Wei Wang, Yan-Kai Liu, Ri-Lei Yu, Jing Li, Tianjiao Zhu, Qianqun Gu, De-Hai Li
Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion. Journal of medicinal chemistry 63 (13) (2020)
Qingliang Xu, Han-Shen Tae, Zihao Wang, Tao Jiang, David J Adams, Ri-Lei Yu
Rational Design of α-Conotoxin RegIIA Analogues Selectively Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning. ACS chemical neuroscience 11 (18) (2020)
Ri-Lei Yu, Huijie Liu, Baishi Wang, Peta J Harvey, Ningning Wei, Yan-Yan Chu
Synthesis and biological activity study of the retro-isomer of RhTx against TRPV1. RSC advances 10 (4) (2020)
YanYan Chu, PeiJu Qiu, Ri-Lei Yu
Centipede Venom Peptides Acting on Ion Channels. Toxins 12 (4) (2020)
Jiazhen Liang, Han-Shen Tae, Xiaoxiao Xu, Tao Jiang, David J Adams, Ri-Lei Yu
Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors. Journal of medicinal chemistry 63 (6) (2020)
Ri-Lei Yu, Jiayi Wang, Lok-Yan So, Peta J Harvey, Juan Shi, Jiazhen Liang, Qin Dou, Xiao Li, Xiayi Yan, Yen-Hua Huang, Qingliang Xu, Quentin Kaas, Ho-Yin Chow, Kwok-Yin Wong, David J Craik, Xiao-Hua Zhang, Tao Jiang, Yan Wang
Enhanced Activity against Multidrug-Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway. Journal of medicinal chemistry 63 (7) (2020)
Xiaoxiao Xu, Jiazhen Liang, Zheyu Zhang, Tao Jiang, Ri-Lei Yu
Blockade of Human α7 Nicotinic Acetylcholine Receptor by α-Conotoxin ImI Dendrimer: Insight from Computational Simulations. Marine drugs 17 (5) (2019)
Xiaoxiao Xu, Qingliang Xu, Fangling Chen, Juan Shi, Yuntian Liu, Yanyan Chu, Shengbiao Wan, Tao Jiang, Ri-Lei Yu
Role of the disulfide bond on the structure and activity of μ-conotoxin PIIIA in the inhibition of Na V 1.4. RSC advances 9 (2) (2019)
Xin Chu, Han-Shen Tae, Qingliang Xu, Tao Jiang, David J Adams, Ri-Lei Yu
α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement. ACS chemical neuroscience 10 (10) (2019)
Ri-Lei Yu, Han-Shen Tae, Qingliang Xu, David J Craik, David J Adams, Tao Jiang, Quentin Kaas
Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British journal of pharmacology 176 (15) (2019)
He Ma, Peiju Qiu, Peta J Harvey, Xiao Li, Zheyu Zhang, Qingliang Xu, Jiazhen Liang, Quentin Kaas, David J Craik, Jinbo Yang, Tao Jiang, Xiaolin Bi, Ri-Lei Yu
In Silico Design of MDM2-Targeting Peptides from a Naturally Occurring Constrained Peptide. ChemMedChem 14 (19) (2019)
Siqi Zhang, Qiaoling Song, Xueting Wang, Zhiqiang Wei, Ri-Lei Yu, Xin Wang, Tao Jiang
Virtual Screening Guided Design, Synthesis and Bioactivity Study of Benzisoselenazolones (BISAs) on Inhibition of c-Met and Its Downstream Signalling Pathways. International journal of molecular sciences 20 (10) (2019)
Ri-Lei Yu, Han-Shen Tae, Nargis Tabassum, Juan Shi, Tao Jiang, David J Adams
Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype. Journal of medicinal chemistry 61 (10) (2018)
Qianyun Ma, Han-Shen Tae, Guanzhao Wu, Tao Jiang, Ri-Lei Yu
Exploring the Relationship between Nicotinic Acetylcholine Receptor Ligand Size, Efficiency, Efficacy, and C-Loop Opening. Journal of chemical information and modeling 57 (8) (2017)

Ri-Lei Yu.css-eqlu8i{font-size:small;padding-left:4px;} (Rilei Yu, RiLei Yu)

Publication Activity (10 Years)

Top Topics

Top Venues

Ri-Lei Yu (Rilei Yu, RiLei Yu)