Romano Silvestri

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 29

Top Venues

Molecules (Basel, Switzerland)

Viruses

Journal of medicinal chemistry

ChemMedChem

Università degli Studi di Roma La Sapienza

Università degli Studi di Roma La Sapienza (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Università degli Studi di Roma La Sapienza Dec 30 2010

Italy

Full Professor :: Drug Chemistry and Technologies

Università degli Studi di Roma La Sapienza Nov 01 1998 - Dec 29 2010

Italy

Associate Professor :: Pharmaceutical Sciences

Università degli Studi di Roma La Sapienza Jan 10 1991 - Oct 31 1998

Italy

Assistant Professor :: Pharmaceutical Sciences

Education History

Università degli Studi di Roma La Sapienza Nov 01 1985 - Oct 31 1988

Italy

PHD :: Pharmaceutical Sciences

Publications

Domiziana Masci, Michela Puxeddu, Romano Silvestri, Giuseppe La Regina
Metabolic Rewiring in Cancer: Small Molecule Inhibitors in Colorectal Cancer Therapy. Molecules (Basel, Switzerland) 29 (9) (2024)
Domiziana Masci, Michela Puxeddu, Romano Silvestri, Giuseppe La Regina
Metabolic Rewiring in Cancer: Small Molecule Inhibitors in Colorectal Cancer Therapy. Molecules (Basel, Switzerland) 29 (9) (2024)
Michela Puxeddu, Manuela Donalisio, Joachim Jakob Bugert, Angela Corona, Paolo Cocomazzi, Mario Milani, Friederike Hucke, Irene Arduino, Francesca Esposito, Paolo Moretti, María Grazia Ortore, Marianna Nalli, Simone Manetto, Giulia Mazzoccanti, Chiara Bigogno, Giulio M Dondio, Pietro Sciò, Antonio Coluccia, Matteo Fracella, Guido Antonelli, David Lembo, Enzo Tramontano, Romano Silvestri, Eloise Mastrangelo, Giuseppe La Regina
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses. ACS infectious diseases (2024)
Marianna Nalli, Laura Di Magno, Yichao Wen, Xin Liu, Michele D'Ambrosio, Michela Puxeddu, Anastasia Parisi, Jessica Sebastiani, Andrea Sorato, Antonio Coluccia, Silvia Ripa, Fiorella Di Pastena, Davide Capelli, Roberta Montanari, Domiziana Masci, Andrea Urbani, Chiara Naro, Claudio Sette, Viviana Orlando, Sara D'Angelo, Stefano Biagioni, Chiara Bigogno, Giulio Dondio, Arianna Pastore, Mariano Stornaiuolo, Gianluca Canettieri, Te Liu, Romano Silvestri, Giuseppe La Regina
Novel N -(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent. ACS pharmacology & translational science 6 (7) (2023)
Francesca Romana Mammone, Leo Zanitti, Michela Puxeddu, Giuseppe La Regina, Romano Silvestri, Anna Borioni, Roberto Cirilli
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations. Molecules (Basel, Switzerland) 28 (1) (2023)
Domiziana Masci, Chiara Naro, Michela Puxeddu, Andrea Urbani, Claudio Sette, Giuseppe La Regina, Romano Silvestri
Recent Advances in Drug Discovery for Triple-Negative Breast Cancer Treatment. Molecules (Basel, Switzerland) 28 (22) (2023)
Francesca Romana Mammone, Leo Zanitti, Michela Puxeddu, Giuseppe La Regina, Romano Silvestri, Anna Borioni, Roberto Cirilli
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations. Molecules (Basel, Switzerland) 28 (1) (2023)
Szabolcs Dvorácskó, Marilisa Pia Dimmito, Jessica Sebastiani, Giuseppe La Regina, Romano Silvestri, Stefano Pieretti, Azzurra Stefanucci, Csaba Tömböly, Adriano Mollica
Rimonabant-Based Compounds Bearing Hydrophobic Amino Acid Derivatives as Cannabinoid Receptor Subtype 1 Ligands. ACS medicinal chemistry letters 14 (4) (2023)
Francesca Romana Mammone, Leo Zanitti, Michela Puxeddu, Giuseppe La Regina, Romano Silvestri, Anna Borioni, Roberto Cirilli
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations. Molecules (Basel, Switzerland) 28 (1) (2023)
Domiziana Masci, Michela Puxeddu, Laura Di Magno, Michele D'Ambrosio, Anastasia Parisi, Marianna Nalli, Ruoli Bai, Antonio Coluccia, Pietro Sciò, Viviana Orlando, Sara D'Angelo, Stefano Biagioni, Andrea Urbani, Ernest Hamel, Alessio Nocentini, Serena Filiberti, Marta Turati, Roberto Ronca, Joanna Kopecka, Chiara Riganti, Cinzia Fionda, Rosa Bordone, Giorgia Della Rocca, Gianluca Canettieri, Claudiu T Supuran, Romano Silvestri, Giuseppe La Regina
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1 H -pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells. Journal of medicinal chemistry (2023)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Michela Puxeddu, Jianchao Wu, Ruoli Bai, Michele D'Ambrosio, Marianna Nalli, Antonio Coluccia, Simone Manetto, Alessia Ciogli, Domiziana Masci, Andrea Urbani, Cinzia Fionda, Sonia Coni, Rosa Bordone, Gianluca Canettieri, Chiara Bigogno, Giulio Dondio, Ernest Hamel, Te Liu, Romano Silvestri, Giuseppe La Regina
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor. Journal of medicinal chemistry 65 (23) (2022)
Antonio Coluccia, Marianna Bufano, Giuseppe La Regina, Michela Puxeddu, Angelo Toto, Alessio Paone, Amani Bouzidi, Giorgia Musto, Nadia Badolati, Viviana Orlando, Stefano Biagioni, Domiziana Masci, Chiara Cantatore, Roberto Cirilli, Francesca Cutruzzolà, Stefano Gianni, Mariano Stornaiuolo, Romano Silvestri
Anticancer Activity of ( S )-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)- N -(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1 H -indole-2-carboxamide (RS4690), a New Dishevelled 1 Inhibitor. Cancers 14 (5) (2022)
Marianna Nalli, Domiziana Masci, Andrea Urbani, Giuseppe La Regina, Romano Silvestri
Emerging Direct Targeting β-Catenin Agents. Molecules (Basel, Switzerland) 27 (22) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Jana Van Dycke, Michela Puxeddu, Giuseppe La Regina, Eloise Mastrangelo, Delia Tarantino, Jasper Rymenants, Jessica Sebastiani, Marianna Nalli, Jelle Matthijnssens, Johan Neyts, Romano Silvestri, Joana Rocha-Pereira
Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance. Pharmaceuticals (Basel, Switzerland) 14 (10) (2021)
Marianna Nalli, Michela Puxeddu, Giuseppe La Regina, Stefano Gianni, Romano Silvestri
Emerging Therapeutic Agents for Colorectal Cancer. Molecules (Basel, Switzerland) 26 (24) (2021)
Marianna Bufano, Marion Laudette, Jean-Paul Blondeau, Frank Lezoualc'h, Marianna Nalli, Romano Silvestri, Andrea Brancale, Antonio Coluccia
Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics. Journal of computer-aided molecular design 34 (11) (2020)
Francesca Malagrinò, Antonio Coluccia, Marianna Bufano, Giuseppe La Regina, Michela Puxeddu, Angelo Toto, Lorenzo Visconti, Alessio Paone, Maria Chiara Magnifico, Francesca Troilo, Francesca Cutruzzolà, Romano Silvestri, Stefano Gianni
Targeting the Interaction between the SH3 Domain of Grb2 and Gab2. Cells 9 (11) (2020)
Laura Di Magno, Fiorella Di Pastena, Michela Puxeddu, Giuseppe La Regina, Antonio Coluccia, Alessia Ciogli, Simone Manetto, Marella Maroder, Gianluca Canettieri, Romano Silvestri, Marianna Nalli
Sulfonamide Inhibitors of β-Catenin Signaling as Anticancer Agents with Different Output on c-MYC. ChemMedChem 15 (23) (2020)
Simone Pippa, Cecilia Mannironi, Valerio Licursi, Luca Bombardi, Gianni Colotti, Enrico Cundari, Adriano Mollica, Antonio Coluccia, Valentina Naccarato, Giuseppe La Regina, Romano Silvestri, Rodolfo Negri
Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B. Molecules (Basel, Switzerland) 24 (9) (2019)
Laurène Da Costa, Els Scheers, Antonio Coluccia, Adriano Casulli, Manon Roche, Carole Di Giorgio, Johan Neyts, Thierry Terme, Roberto Cirilli, Giuseppe La Regina, Romano Silvestri, Carmen Mirabelli, Patrice Vanelle
Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication. Journal of medicinal chemistry 61 (18) (2018)
Gennaro Riccio, Sara Bottone, Giuseppe La Regina, Nadia Badolati, Sara Passacantilli, Giovanni Battista Rossi, Antonella Accardo, Monica Dentice, Romano Silvestri, Ettore Novellino, Mariano Stornaiuolo
A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist. Biochemistry 57 (5) (2018)
Simona Daniele, Deborah Pietrobono, Barbara Costa, Mariateresa Giustiniano, Valeria La Pietra, Chiara Giacomelli, Giuseppe La Regina, Romano Silvestri, Sabrina Taliani, Maria Letizia Trincavelli, Federico Da Settimo, Ettore Novellino, Claudia Martini, Luciana Marinelli
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells. ACS chemical neuroscience 9 (1) (2017)
Valeria Famiglini, Giuseppe La Regina, Antonio Coluccia, Domiziana Masci, Andrea Brancale, Roger Badia, Eva Riveira-Muñoz, José A Esté, Emmanuele Crespan, Alessandro Brambilla, Giovanni Maga, Myriam Catalano, Cristina Limatola, Francesca Romana Formica, Roberto Cirilli, Ettore Novellino, Romano Silvestri
Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents. Journal of medicinal chemistry 60 (15) (2017)
Mariateresa Giustiniano, Simona Daniele, Sveva Pelliccia, Valeria La Pietra, Deborah Pietrobono, Diego Brancaccio, Sandro Cosconati, Anna Messere, Stefano Giuntini, Linda Cerofolini, Marco Fragai, Claudio Luchinat, Sabrina Taliani, Giuseppe La Regina, Federico Da Settimo, Romano Silvestri, Claudia Martini, Ettore Novellino, Luciana Marinelli
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity. Journal of medicinal chemistry 60 (19) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Romano Silvestri