Luke A Gilbert (L A Gilbert, Luke Gilbert)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Venues

Nature communications

Nature

eLife

Nature biotechnology

University of California, San Francisco

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California, San Francisco Apr 01 2017

United States

Assistant Professor :: Urology

Education History

Massachusetts Institute of Technology

United States

PHD :: Biology

University of California Los Angeles

United States

BSC :: MIMG

Publications

Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature (2024)
Matvei Khoroshkin, Daniel Asarnow, Shaopu Zhou, Albertas Navickas, Aidan Winters, Jackson Goudreau, Simon K Zhou, Johnny Yu, Christina Palka, Lisa Fish, Ashir Borah, Kian Yousefi, Christopher Carpenter, Karl Mark Ansel, Yifan Cheng, Luke A Gilbert, Hani Goodarzi
A systematic search for RNA structural switches across the human transcriptome. Nature methods (2024)
C C-S Hsiung, C M Wilson, N A Sambold, R Dai, Q Chen, N Teyssier, S Misiukiewicz, Abolfazl Arab, Thomas A O'Loughlin, Joshua C Cofsky, Junwei Shi, Luke A Gilbert
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations. Nature biotechnology (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature (2024)
C C-S Hsiung, C M Wilson, N A Sambold, R Dai, Q Chen, N Teyssier, S Misiukiewicz, Abolfazl Arab, Thomas A O'Loughlin, Joshua C Cofsky, Junwei Shi, Luke A Gilbert
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations. Nature biotechnology (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
C C-S Hsiung, C M Wilson, N A Sambold, R Dai, Q Chen, N Teyssier, S Misiukiewicz, Abolfazl Arab, Thomas A O'Loughlin, Joshua C Cofsky, Junwei Shi, Luke A Gilbert
Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations. Nature biotechnology (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Siyuan John Liu, Tim J Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C Dougherty, Kyla Foster, William C Chen, Javier E Villanueva-Meyer, Danielle L Swaney, Harish N Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D Breshears, Ursula E Lang, Charlotte D Eaton, Kamir J Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V Lien, David Wu, Steve E Braunstein, Penny K Sneed, Stephen T Magill, Daniel Lim, Michael W McDermott, Mitchel S Berger, Arie Perry, Nevan J Krogan, Marlan R Hansen, Matthew H Spitzer, Luke A Gilbert, Philip V Theodosopoulos, David R Raleigh
Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nature communications 15 (1) (2024)
Brian J Woo, Ruhollah Moussavi-Baygi, Heather Karner, Mehran Karimzadeh, Kristle Garcia, Tanvi Joshi, Keyi Yin, Albertas Navickas, Luke A Gilbert, Bo Wang, Hosseinali Asgharian, Felix Y Feng, Hani Goodarzi
Integrative identification of non-coding regulatory regions driving metastatic prostate cancer. bioRxiv : the preprint server for biology (2023)
Ralf Schmidt, Carl C Ward, Rama Dajani, Zev Armour-Garb, Mineto Ota, Vincent Allain, Rosmely Hernandez, Madeline Layeghi, Galen Xing, Laine Goudy, Dmytro Dorovskyi, Charlotte Wang, Yan Yi Chen, Chun Jimmie Ye, Brian R Shy, Luke A Gilbert, Justin Eyquem, Jonathan K Pritchard, Stacie E Dodgson, Alexander Marson
Base-editing mutagenesis maps alleles to tune human T cell functions. Nature (2023)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Boyang Zhao, Yiyun Rao, Scott Leighow, Edward P O'Brien, Luke A Gilbert, Justin R Pritchard
A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments. Nature communications 13 (1) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Luke A Gilbert
Keap1ing an eye on Slc33A1. Nature cancer 1 (6) (2022)
Kevin Lou, Douglas R Wassarman, Tangpo Yang, YiTing Paung, Ziyang Zhang, Thomas A O'Loughlin, Megan K Moore, Regina K Egan, Patricia Greninger, Cyril H Benes, Markus A Seeliger, Jack Taunton, Luke A Gilbert, Kevan M Shokat
IFITM proteins assist cellular uptake of diverse linked chemotypes. Science (New York, N.Y.) 378 (6624) (2022)
Luke A Gilbert
Mapping cancer genetics at single-cell resolution. Science translational medicine 12 (558) (2021)
Rajdeep Das, Martin Sjostrom, Raunak Shrestha, Christopher Yogodzinski, Emily A Egusa, Lisa N Chesner, William S Chen, Jonathan Chou, Donna K Dang, Jason T Swinderman, Alex Ge, Junjie T Hua, Shaheen Kabir, David A Quigley, Eric J Small, Alan Ashworth, Felix Y Feng, Luke A Gilbert
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer. Nature communications 12 (1) (2021)
Laralynne Przybyla, Luke A Gilbert
A new era in functional genomics screens. Nature reviews. Genetics (2021)
Christopher Yogodzinski, Abolfazl Arab, Justin R Pritchard, Hani Goodarzi, Luke A Gilbert
A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy. Genome medicine 13 (1) (2021)
Shuang G Zhao, William S Chen, Haolong Li, Adam Foye, Meng Zhang, Martin Sjostrom, Rahul Aggarwal, Denise Playdle, Arnold Liao, Joshi J Alumkal, Rajdeep Das, Jonathan Chou, Junjie T Hua, Travis J Barnard, Adina M Bailey, Eric D Chow, Marc D Perry, Ha X Dang, Rendong Yang, Ruhollah Moussavi-Baygi, Li Zhang, Mohammed Alshalalfa, S Laura Chang, Kathleen E Houlahan, Yu-Jia Shiah, Tomasz M Beer, George Thomas, Kim N Chi, Martin Gleave, Amina Zoubeidi, Robert E Reiter, Matthew B Rettig, Owen Witte, M Yvonne Kim, Lawrence Fong, Daniel E Spratt, Todd M Morgan, Rohit Bose, Franklin W Huang, Hui Li, Lisa Chesner, Tanushree Shenoy, Hani Goodarzi, Irfan A Asangani, Shahneen Sandhu, Joshua M Lang, Nupam P Mahajan, Primo N Lara, Christopher P Evans, Phillip Febbo, Serafim Batzoglou, Karen E Knudsen, Housheng Hansen He, Jiaoti Huang, Wilbert Zwart, Joseph F Costello, Jianhua Luo, Scott A Tomlins, Alexander W Wyatt, Scott M Dehm, Alan Ashworth, Luke A Gilbert, Paul C Boutros, Kyle Kai-How Farh, Sunita Shankar, Christopher A Maher, Eric J Small, David A Quigley, Felix Y Feng
The DNA methylation landscape of advanced prostate cancer. Nature genetics 52 (8) (2020)
Kevin Lou, Veronica Steri, Alex Y Ge, Y Christina Hwang, Christopher H Yogodzinski, Arielle R Shkedi, Alex L M Choi, Dominique C Mitchell, Danielle L Swaney, Byron C Hann, John D Gordan, Kevan M Shokat, Luke A Gilbert
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Science signaling 12 (583) (2019)
Kevin Lou, Luke A Gilbert, Kevan M Shokat
A Bounty of New Challenging Targets in Oncology for Chemical Discovery. Biochemistry 58 (31) (2019)
Thomas M Norman, Max A Horlbeck, Joseph M Replogle, Alex Y Ge, Albert Xu, Marco Jost, Luke A Gilbert, Jonathan S Weissman
Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science (New York, N.Y.) 365 (6455) (2019)
Hao Shao, Xiaokai Li, Michael A Moses, Luke A Gilbert, Chakrapani Kalyanaraman, Zapporah T Young, Margarita Chernova, Sara N Journey, Jonathan S Weissman, Byron Hann, Matthew P Jacobson, Len Neckers, Jason E Gestwicki
Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). Journal of medicinal chemistry 61 (14) (2018)
Ross C Wilson, Luke A Gilbert
The Promise and Challenge of In Vivo Delivery for Genome Therapeutics. ACS chemical biology 13 (2) (2017)

Luke A Gilbert.css-eqlu8i{font-size:small;padding-left:4px;} (L A Gilbert, Luke Gilbert)

Publication Activity (10 Years)

Top Topics

Top Venues

Luke A Gilbert (L A Gilbert, Luke Gilbert)