Stephan A Sieber

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 100

Top Venues

Angewandte Chemie (International ed. in English)

Chembiochem : a European journal of chemical biology

Communications biology

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Bernardo Miller Naranjo, Michael Zollo, Stephan A Sieber, Oliver Lieleg
Lubricity, wear prevention, and anti-biofouling properties of macromolecular coatings for endotracheal tubes. Biomaterials science 12 (5) (2024)
Yudong Hu, Dietrich Mostert, Christina Orgler, Oliver Andler, Hans Zischka, Uli Kazmaier, Angelika M Vollmar, Simone Braig, Stephan A Sieber, Stefan Zahler
Thermal Proteome Profiling Reveals Insight to Antiproliferative and Pro-Apoptotic Effects of Lagunamide A in the Modulation of DNA Damage Repair. Chembiochem : a European journal of chemical biology 25 (13) (2024)
Noé Osorio Reineke, Franziska A V Elsen, Hanusch A Grab, Dietrich Mostert, Stephan A Sieber, Thorsten Bach
Synthesis and biological evaluation of vioprolide B and its dehydrobutyrine-glycine analogue. Chemical communications (Cambridge, England) 60 (63) (2024)
Stuart A Ruddell, Dietrich Mostert, Stephan A Sieber
Target identification of usnic acid in bacterial and human cells. RSC chemical biology 5 (7) (2024)
Amber M Scharnow, Amy E Solinski, Sebastian Rowe, Ines Hübner, Hua Zhang, Elana Shaw, Julia E Page, Hui Wu, Stephan A Sieber, William M Wuest
In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society 146 (33) (2024)
Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A Sieber
Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases. Biochemistry 63 (5) (2024)
Davide Boldini, Lukas Friedrich, Daniel Kuhn, Stephan A Sieber
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery. ACS central science 10 (4) (2024)
Noé Osorio Reineke, Franziska A V Elsen, Hanusch A Grab, Dietrich Mostert, Stephan A Sieber, Thorsten Bach
Synthesis and biological evaluation of vioprolide B and its dehydrobutyrine-glycine analogue. Chemical communications (Cambridge, England) (2024)
Maximilian G Schuh, Davide Boldini, Stephan A Sieber
Synergizing Chemical Structures and Bioassay Descriptions for Enhanced Molecular Property Prediction in Drug Discovery. Journal of chemical information and modeling 64 (12) (2024)
Maximilian G Schuh, Davide Boldini, Stephan A Sieber
Synergizing Chemical Structures and Bioassay Descriptions for Enhanced Molecular Property Prediction in Drug Discovery. Journal of chemical information and modeling 64 (12) (2024)
Josef Braun, Yudong Hu, Adrian T Jauch, Thomas F Gronauer, Julia Mergner, Nina C Bach, Franziska R Traube, Stefan Zahler, Stephan A Sieber
Neocarzilin Inhibits Cancer Cell Proliferation via BST-2 Degradation, Resulting in Lipid Raft-Trapped EGFR. JACS Au 4 (5) (2024)
Maximilian Hohmann, Valentina Brunner, Widya Johannes, Dominik Schum, Laura M Carroll, Tianzhe Liu, Daisuke Sasaki, Johanna Bosch, Thomas Clavel, Stephan A Sieber, Georg Zeller, Markus Tschurtschenthaler, Klaus-Peter Janssen, Tobias A M Gulder
Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro. Communications biology 7 (1) (2024)
Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A Sieber
Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases. Biochemistry 63 (5) (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry 22 (10) (2024)
Davide Boldini, Lukas Friedrich, Daniel Kuhn, Stephan A Sieber
Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery. ACS central science 10 (4) (2024)
Amber M Scharnow, Amy E Solinski, Sebastian Rowe, Ines Hübner, Hua Zhang, Elana Shaw, Julia E Page, Hui Wu, Stephan A Sieber, William M Wuest
In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society 146 (33) (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry 22 (10) (2024)
Amber M Scharnow, Amy E Solinski, Sebastian Rowe, Ines Hübner, Hua Zhang, Elana Shaw, Julia E Page, Hui Wu, Stephan A Sieber, William M Wuest
In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society 146 (33) (2024)
Maximilian G Schuh, Davide Boldini, Stephan A Sieber
Synergizing Chemical Structures and Bioassay Descriptions for Enhanced Molecular Property Prediction in Drug Discovery. Journal of chemical information and modeling (2024)
Bernardo Miller Naranjo, Michael Zollo, Stephan A Sieber, Oliver Lieleg
Lubricity, wear prevention, and anti-biofouling properties of macromolecular coatings for endotracheal tubes. Biomaterials science 12 (5) (2024)
Yudong Hu, Dietrich Mostert, Christina Orgler, Oliver Andler, Hans Zischka, Uli Kazmaier, Angelika M Vollmar, Simone Braig, Stephan A Sieber, Stefan Zahler
Thermal Proteome Profiling Reveals Insight to Antiproliferative and Pro-Apoptotic Effects of Lagunamide A in the Modulation of DNA Damage Repair. Chembiochem : a European journal of chemical biology (2024)
Shu-Yu Chen, Michaela K Fiedler, Thomas F Gronauer, Olesia Omelko, Marie-Kristin von Wrisberg, Tao Wang, Sabine Schneider, Stephan A Sieber, Martin Zacharias
Unraveling the mechanism of small molecule induced activation of Staphylococcus aureus signal peptidase IB. Communications biology 7 (1) (2024)
Shu-Yu Chen, Michaela K Fiedler, Thomas F Gronauer, Olesia Omelko, Marie-Kristin von Wrisberg, Tao Wang, Sabine Schneider, Stephan A Sieber, Martin Zacharias
Unraveling the mechanism of small molecule induced activation of Staphylococcus aureus signal peptidase IB. Communications biology 7 (1) (2024)
Alexandra Geißler, Howard Junca, Andreas M Kany, Lena J Daumann, Anna Katharina Herta Hirsch, Dietmar H Pieper, Stephan A Sieber
Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes. Chemical science 15 (30) (2024)
Josef Braun, Yudong Hu, Adrian T Jauch, Thomas F Gronauer, Julia Mergner, Nina C Bach, Franziska R Traube, Stefan Zahler, Stephan A Sieber
Neocarzilin Inhibits Cancer Cell Proliferation via BST-2 Degradation, Resulting in Lipid Raft-Trapped EGFR. JACS Au 4 (5) (2024)
Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A Sieber
Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases. Biochemistry 63 (5) (2024)
Stuart A Ruddell, Dietrich Mostert, Stephan A Sieber
Target identification of usnic acid in bacterial and human cells. RSC chemical biology 5 (7) (2024)
Dominik Schum, Franziska A V Elsen, Stuart Ruddell, Kenji Schorpp, Howard Junca, Mathias Müsken, Shu-Yu Chen, Michaela K Fiedler, Thomas Pickl, Dietmar H Pieper, Kamyar Hadian, Martin Zacharias, Stephan A Sieber
Screening Privileged Alkyl Guanidinium Motifs under Host-Mimicking Conditions Reveals a Novel Antibiotic with an Unconventional Mode of Action. JACS Au 4 (8) (2024)
Maximilian Hohmann, Valentina Brunner, Widya Johannes, Dominik Schum, Laura M Carroll, Tianzhe Liu, Daisuke Sasaki, Johanna Bosch, Thomas Clavel, Stephan A Sieber, Georg Zeller, Markus Tschurtschenthaler, Klaus-Peter Janssen, Tobias A M Gulder
Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro. Communications biology 7 (1) (2024)
Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A Sieber
Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases. Biochemistry 63 (5) (2024)
Maximilian G Schuh, Davide Boldini, Stephan A Sieber
Synergizing Chemical Structures and Bioassay Descriptions for Enhanced Molecular Property Prediction in Drug Discovery. Journal of chemical information and modeling 64 (12) (2024)
Shu-Yu Chen, Michaela K Fiedler, Thomas F Gronauer, Olesia Omelko, Marie-Kristin von Wrisberg, Tao Wang, Sabine Schneider, Stephan A Sieber, Martin Zacharias
Unraveling the mechanism of small molecule induced activation of Staphylococcus aureus signal peptidase IB. Communications biology 7 (1) (2024)
Bernardo Miller Naranjo, Michael Zollo, Stephan A Sieber, Oliver Lieleg
Lubricity, wear prevention, and anti-biofouling properties of macromolecular coatings for endotracheal tubes. Biomaterials science (2024)
Amber M Scharnow, Amy E Solinski, Sebastian Rowe, Ines Hübner, Hua Zhang, Elana Shaw, Julia E Page, Hui Wu, Stephan A Sieber, William M Wuest
In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry 22 (10) (2024)
Yudong Hu, Dietrich Mostert, Christina Orgler, Oliver Andler, Hans Zischka, Uli Kazmaier, Angelika M Vollmar, Simone Braig, Stephan A Sieber, Stefan Zahler
Thermal Proteome Profiling Reveals Insight to Antiproliferative and Pro-Apoptotic Effects of Lagunamide A in the Modulation of DNA Damage Repair. Chembiochem : a European journal of chemical biology 25 (13) (2024)
Maximilian Hohmann, Valentina Brunner, Widya Johannes, Dominik Schum, Laura M Carroll, Tianzhe Liu, Daisuke Sasaki, Johanna Bosch, Thomas Clavel, Stephan A Sieber, Georg Zeller, Markus Tschurtschenthaler, Klaus-Peter Janssen, Tobias A M Gulder
Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro. Communications biology 7 (1) (2024)
Alexandra Geißler, Howard Junca, Andreas M Kany, Lena J Daumann, Anna Katharina Herta Hirsch, Dietmar H Pieper, Stephan A Sieber
Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes. Chemical science 15 (30) (2024)
Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A Sieber
Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases. Biochemistry (2024)
Shu-Yu Chen, Michaela K Fiedler, Thomas F Gronauer, Olesia Omelko, Marie-Kristin von Wrisberg, Tao Wang, Sabine Schneider, Stephan A Sieber, Martin Zacharias
Unraveling the mechanism of small molecule induced activation of Staphylococcus aureus signal peptidase IB. Communications biology 7 (1) (2024)
Amber M Scharnow, Amy E Solinski, Sebastian Rowe, Ines Hübner, Hua Zhang, Elana Shaw, Julia E Page, Hui Wu, Stephan A Sieber, William M Wuest
In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society 146 (33) (2024)
Angela Weigert-Muñoz, Kevin M Meighen-Berger, Stephan M Hacker, Matthias J Feige, Stephan A Sieber
A chemical probe unravels the reactive proteome of health-associated catechols. Chemical science 14 (32) (2023)
Angela Weigert-Muñoz, Wei-Ning Zhao, Stephan A Sieber
Monitoring host-pathogen interactions using chemical proteomics. RSC chemical biology 5 (2) (2023)
Michaela K Fiedler, Jonas Drechsel, Ronny Schmidt, Peter B Luppa, Nina C Bach, Stephan A Sieber
Rapid Diagnostic Platform for Personalized Vitamin B6 Detection in Erythrocytes via PLP Cofactor Mimics. ACS chemical biology (2023)
Isabel V L Wilkinson, Max Bottlinger, Yassmine El Harraoui, Stephan A Sieber
Profiling the Heme-Binding Proteomes of Bacteria Using Chemical Proteomics. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Angela Weigert-Muñoz, Wei-Ning Zhao, Stephan A Sieber
Monitoring host-pathogen interactions using chemical proteomics. RSC chemical biology 5 (2) (2023)
Isabel V L Wilkinson, Gabriel Castro-Falcón, Maria C Roda-Serrat, Trevor N Purdy, Jan Straetener, Melanie M Brauny, Lisa Maier, Heike Brötz-Oesterhelt, Lars Porskjær Christensen, Stephan A Sieber, Chambers C Hughes
The Cyanobacterial "Nutraceutical" Phycocyanobilin Inhibits Cysteine Protease Legumain. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Isabel V L Wilkinson, Max Bottlinger, Yassmine El Harraoui, Stephan A Sieber
Profiling the Heme-Binding Proteomes of Bacteria Using Chemical Proteomics. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Isabel V L Wilkinson, Max Bottlinger, Yassmine El Harraoui, Stephan A Sieber
Profiling the Heme-Binding Proteomes of Bacteria Using Chemical Proteomics. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Isabel V L Wilkinson, Gabriel Castro-Falcón, Maria C Roda-Serrat, Trevor N Purdy, Jan Straetener, Melanie M Brauny, Lisa Maier, Heike Brötz-Oesterhelt, Lars Porskjær Christensen, Stephan A Sieber, Chambers C Hughes
The Cyanobacterial "Nutraceutical" Phycocyanobilin Inhibits Cysteine Protease Legumain. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Isabel V L Wilkinson, Gabriel Castro-Falcón, Maria C Roda-Serrat, Trevor N Purdy, Jan Straetener, Melanie M Brauny, Lisa Maier, Heike Brötz-Oesterhelt, Lars Porskjær Christensen, Stephan A Sieber, Chambers C Hughes
The Cyanobacterial "Nutraceutical" Phycocyanobilin Inhibits Cysteine Protease Legumain. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Isabel V L Wilkinson, Max Bottlinger, Yassmine El Harraoui, Stephan A Sieber
Profiling the Heme-Binding Proteomes of Bacteria Using Chemical Proteomics. Angewandte Chemie (International ed. in English) 62 (9) (2023)
Dorothea Höpfner, Adam Cichy, Vivian Pogenberg, Christoph Krisp, Soraya Mezouar, Nina C Bach, Jan Grotheer, Sandra Madariaga Zarza, Eric Martinez, Matteo Bonazzi, Matthias J Feige, Stephan A Sieber, Hartmut Schlüter, Aymelt Itzen
The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3. Communications biology 6 (1) (2023)
Isabel V L Wilkinson, Gabriel Castro-Falcón, Maria C Roda-Serrat, Trevor N Purdy, Jan Straetener, Melanie M Brauny, Lisa Maier, Heike Brötz-Oesterhelt, Lars Porskjær Christensen, Stephan A Sieber, Chambers C Hughes
The Cyanobacterial "Nutraceutical" Phycocyanobilin Inhibits Cysteine Protease Legumain. Chembiochem : a European journal of chemical biology (2022)
Kyoko Morimoto, Daniel Krahn, Farnusch Kaschani, Digby Hopkinson-Woolley, Anna Gee, Pierre Buscaill, Shabaz Mohammad, Stephan A Sieber, Benjamin F Cravatt, Christopher J Schofield, van der Hoorn Renier A L
Broad-range metalloprotease profiling in plants uncovers immunity provided by defence-related metalloenzyme. The New phytologist 235 (3) (2022)
Dora Balogh, Konstantin Eckel, Christian Fetzer, Stephan A Sieber
Listeria monocytogenes utilizes the ClpP1/2 proteolytic machinery for fine-tuned substrate degradation at elevated temperatures. RSC chemical biology 3 (7) (2022)
Laura Reinhardt, Dhana Thomy, Markus Lakemeyer, Linda Maria Westermann, Joaquin Ortega, Stephan A Sieber, Peter Sass, Heike Brötz-Oesterhelt
Antibiotic Acyldepsipeptides Stimulate the Streptomyces Clp-ATPase/ClpP Complex for Accelerated Proteolysis. mBio (2022)
Till Reinhardt, Kyu M Lee, Lukas Niederegger, Corinna R Hess, Stephan A Sieber
Indolin-2-one Nitroimidazole Antibiotics Exhibit an Unexpected Dual Mode of Action. ACS chemical biology 17 (11) (2022)
Isabel V L Wilkinson, Martin Pfanzelt, Stephan A Sieber
Functionalised Cofactor Mimics for Interactome Discovery and Beyond. Angewandte Chemie (International ed. in English) 61 (29) (2022)
Martin Pfanzelt, Thomas E Maher, Ramona M Absmeier, Markus Schwarz, Stephan A Sieber
Tailored Pyridoxal Probes Unravel Novel Cofactor-Dependent Targets and Antibiotic Hits in Critical Bacterial Pathogens. Angewandte Chemie (International ed. in English) 61 (24) (2022)
Markus Schwarz, Ines Hübner, Stephan A Sieber
Tailored Phenyl Esters Inhibit ClpXP and Attenuate Staphylococcus aureus α-Hemolysin Secretion. Chembiochem : a European journal of chemical biology 23 (16) (2022)
Isabel V L Wilkinson, Max Bottlinger, Yassmine El Harraoui, Stephan A Sieber
Profiling the Heme-Binding Proteomes of Bacteria Using Chemical Proteomics. Angewandte Chemie (International ed. in English) (2022)
Jonas F Schlagintweit, Christian H G Jakob, Kevin Meighen-Berger, Thomas F Gronauer, Angela Weigert Muñoz, Vanessa Weiß, Matthias J Feige, Stephan A Sieber, João D G Correia, Fritz E Kühn
Fluorescent palladium(II) and platinum(II) NHC/1,2,3-triazole complexes: antiproliferative activity and selectivity against cancer cells. Dalton transactions (Cambridge, England : 2003) 50 (6) (2021)
Patrick W A Allihn, Mathias W Hackl, Christina Ludwig, Stephan M Hacker, Stephan A Sieber
A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling. Chemical science 12 (13) (2021)
Nanaji Arisetti, Hazel L S Fuchs, Janetta Coetzee, Manuel Orozco, Dominik Ruppelt, Armin Bauer, Dominik Heimann, Eric Kuhnert, Satya P Bhamidimarri, Jayesh A Bafna, Bettina Hinkelmann, Konstantin Eckel, Stephan A Sieber, Peter P Mueller, Jennifer Herrmann, Daniel Krug, Mathias Winterhalter, Claudia Steinem, Mark Brönstrup
Total synthesis and mechanism of action of the antibiotic armeniaspirol A. Chemical science 12 (48) (2021)
Robert J Mayer, Patrick W A Allihn, Nathalie Hampel, Peter Mayer, Stephan A Sieber, Armin R Ofial
Electrophilic reactivities of cyclic enones and α,β-unsaturated lactones. Chemical science 12 (13) (2021)
Svenja Wiechmann, Benjamin Ruprecht, Theresa Siekmann, Runsheng Zheng, Martin Frejno, Elena Kunold, Thomas Bajaj, Daniel P Zolg, Stephan A Sieber, Nils C Gassen, Bernhard Kuster
Chemical Phosphoproteomics Sheds New Light on the Targets and Modes of Action of AKT Inhibitors. ACS chemical biology 16 (4) (2021)
Christina Kyrousi, Adam C O'Neill, Agnieska Brazovskaja, Zhisong He, Pavel Kielkowski, Laure Coquand, Rossella Di Giaimo, Pierpaolo D' Andrea, Alexander Belka, Andrea Forero Echeverry, Davide Mei, Matteo Lenge, Cristiana Cruceanu, Isabel Y Buchsbaum, Shahryar Khattak, Guimiot Fabien, Elisabeth B Binder, Frances Elmslie, Renzo Guerrini, Alexandre D Baffet, Stephan A Sieber, Barbara Treutlein, Stephen P Robertson, Silvia Cappello
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity. Nature communications 12 (1) (2021)
Hanusch A Grab, Volker C Kirsch, Stephan A Sieber, Thorsten Bach
Total Synthesis of the Cyclic Depsipeptide Vioprolide D via its (Z)-Diastereoisomer. Angewandte Chemie (International ed. in English) 59 (30) (2020)
Kyu Myung Lee, Philipp Le, Stephan A Sieber, Stephan M Hacker
Degrasyn exhibits antibiotic activity against multi-resistant Staphylococcus aureus by modifying several essential cysteines. Chemical communications (Cambridge, England) 56 (19) (2020)
Jonas Drechsel, Christina Kyrousi, Silvia Cappello, Stephan A Sieber
Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC chemical biology 1 (4) (2020)
Barbara Eyermann, Maximilian Meixner, Heike Brötz-Oesterhelt, Iris Antes, Stephan A Sieber
Acyldepsipeptide Probes Facilitate Specific Detection of Caseinolytic Protease P Independent of Its Oligomeric and Activity State. Chembiochem : a European journal of chemical biology 21 (1-2) (2020)
Volker C Kirsch, Christian Fetzer, Stephan A Sieber
Global Inventory of ClpP- and ClpX-Regulated Proteins in Staphylococcus aureus. Journal of proteome research 20 (1) (2020)
Ines Hübner, Jan-Niklas Dienemann, Julia Friederich, Sabine Schneider, Stephan A Sieber
Tailored Cofactor Traps for the in Situ Detection of Hemithioacetal-Forming Pyridoxal Kinases. ACS chemical biology 15 (12) (2020)
Theresa Rauh, Sophie Brameyer, Pavel Kielkowski, Kirsten Jung, Stephan A Sieber
MS-Based in Situ Proteomics Reveals AMPylation of Host Proteins during Bacterial Infection. ACS infectious diseases 6 (12) (2020)
Pavel Kielkowski, Isabel Y Buchsbaum, Tobias Becker, Kathrin Bach, Silvia Cappello, Stephan A Sieber
A Pronucleotide Probe for Live-Cell Imaging of Protein AMPylation. Chembiochem : a European journal of chemical biology 21 (9) (2020)
Robert Macsics, Mathias W Hackl, Christian Fetzer, Dietrich Mostert, Jennifer K Bender, Franziska Layer, Stephan A Sieber
Comparative Target Analysis of Chlorinated Biphenyl Antimicrobials Highlights MenG as a Molecular Target of Triclocarban. Applied and environmental microbiology 86 (16) (2020)
Pavel Kielkowski, Isabel Y Buchsbaum, Volker C Kirsch, Nina C Bach, Micha Drukker, Silvia Cappello, Stephan A Sieber
FICD activity and AMPylation remodelling modulate human neurogenesis. Nature communications 11 (1) (2020)
Christian Fetzer, Vadim S Korotkov, Stephan A Sieber
Hydantoin analogs inhibit the fully assembled ClpXP protease without affecting the individual peptidase and chaperone domains. Organic & biomolecular chemistry 17 (30) (2019)
Anja Fux, Stephan A Sieber
Biochemical and Proteomic Studies of Human Pyridoxal 5'-Phosphate-Binding Protein (PLPBP). ACS chemical biology 15 (1) (2019)
João P L Coelho, Matthias Stahl, Nicolas Bloemeke, Kevin Meighen-Berger, Carlos Piedrafita Alvira, Zai-Rong Zhang, Stephan A Sieber, Matthias J Feige
Publisher Correction: A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration. Nature communications 10 (1) (2019)
Markus Lakemeyer, Eva Bertosin, Friederike Möller, Dora Balogh, Ralf Strasser, Hendrik Dietz, Stephan A Sieber
Tailored Peptide Phenyl Esters Block ClpXP Proteolysis by an Unusual Breakdown into a Heptamer-Hexamer Assembly. Angewandte Chemie (International ed. in English) 58 (21) (2019)
Weining Zhao, Ashley R Cross, Caillan Crowe-McAuliffe, Angela Weigert-Munoz, Erika E Csatary, Amy E Solinski, Joanna Krysiak, Joanna B Goldberg, Daniel N Wilson, Eva Medina, William M Wuest, Stephan A Sieber
The Natural Product Elegaphenone Potentiates Antibiotic Effects against Pseudomonas aeruginosa. Angewandte Chemie (International ed. in English) 58 (25) (2019)
Philipp Le, Matthew B Nodwell, Jürgen Eirich, Stephan A Sieber
A Chemical Proteomic Analysis of Illudin-Interacting Proteins. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (54) (2019)
João P L Coelho, Matthias Stahl, Nicolas Bloemeke, Kevin Meighen-Berger, Carlos Piedrafita Alvira, Zai-Rong Zhang, Stephan A Sieber, Matthias J Feige
A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration. Nature communications 10 (1) (2019)
Philipp Le, Elena Kunold, Robert Macsics, Katharina Rox, Megan C Jennings, Ilke Ugur, Maria Reinecke, Diego Chaves-Moreno, Mathias W Hackl, Christian Fetzer, Franziska A M Mandl, Johannes Lehmann, Vadim S Korotkov, Stephan M Hacker, Bernhard Kuster, Iris Antes, Dietmar H Pieper, Manfred Rohde, William M Wuest, Eva Medina, Stephan A Sieber
Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms. Nature chemistry 12 (2) (2019)
Volker C Kirsch, Christina Orgler, Simone Braig, Irmela Jeremias, David Auerbach, Rolf Müller, Angelika M Vollmar, Stephan A Sieber
The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, Which Is Essential for Ribosome Biogenesis. Angewandte Chemie (International ed. in English) 59 (4) (2019)
Christos Gatsogiannis, Dora Balogh, Felipe Merino, Stephan A Sieber, Stefan Raunser
Cryo-EM structure of the ClpXP protein degradation machinery. Nature structural & molecular biology 26 (10) (2019)
Barbara Hofbauer, Jan Vomacka, Matthias Stahl, Vadim S Korotkov, Megan C Jennings, William M Wuest, Stephan A Sieber
Dual Inhibitor of Staphylococcus aureus Virulence and Biofilm Attenuates Expression of Major Toxins and Adhesins. Biochemistry 57 (11) (2018)
Kilian Vogele, Thomas Frank, Lukas Gasser, Marisa A Goetzfried, Mathias W Hackl, Stephan A Sieber, Friedrich C Simmel, Tobias Pirzer
Towards synthetic cells using peptide-based reaction compartments. Nature communications 9 (1) (2018)
Jonas Drechsel, Franziska A Mandl, Stephan A Sieber
Chemical Probe To Monitor the Parkinsonism-Associated Protein DJ-1 in Live Cells. ACS chemical biology 13 (8) (2018)
Colleen E Keohane, Andrew D Steele, Christian Fetzer, Jittasak Khowsathit, Daria Van Tyne, Lucile Moynié, Michael S Gilmore, John Karanicolas, Stephan A Sieber, William M Wuest
Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase. Journal of the American Chemical Society 140 (5) (2018)
Annabelle Hoegl, Matthew B Nodwell, Volker C Kirsch, Nina C Bach, Martin Pfanzelt, Matthias Stahl, Sabine Schneider, Stephan A Sieber
Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics. Nature chemistry 10 (12) (2018)
Markus Lakemeyer, Weining Zhao, Franziska A Mandl, Peter Hammann, Stephan A Sieber
Thinking Outside the Box-Novel Antibacterials To Tackle the Resistance Crisis. Angewandte Chemie (International ed. in English) 57 (44) (2018)
Matthias Stahl, Vadim S Korotkov, Dóra Balogh, Leonhard M Kick, Malte Gersch, Axel Pahl, Pavel Kielkowski, Klaus Richter, Sabine Schneider, Stephan A Sieber
Selective Activation of Human Caseinolytic Protease P (ClpP). Angewandte Chemie (International ed. in English) 57 (44) (2018)
Christian Fetzer, Vadim S Korotkov, Robert Thänert, Kyu Myung Lee, Martin Neuenschwander, Jens Peter von Kries, Eva Medina, Stephan A Sieber
A Chemical Disruptor of the ClpX Chaperone Complex Attenuates the Virulence of Multidrug-Resistant Staphylococcus aureus. Angewandte Chemie (International ed. in English) 56 (49) (2017)
Johannes Lehmann, Tan-Yun Cheng, Anup Aggarwal, Annie S Park, Evelyn Zeiler, Ravikiran M Raju, Tatos Akopian, Olga Kandror, James C Sacchettini, D Branch Moody, Eric J Rubin, Stephan A Sieber
An Antibacterial β-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis. Angewandte Chemie (International ed. in English) 57 (1) (2017)
Joanna Krysiak, Matthias Stahl, Jan Vomacka, Christian Fetzer, Markus Lakemeyer, Anja Fux, Stephan A Sieber
Quantitative Map of β-Lactone-Induced Virulence Regulation. Journal of proteome research 16 (3) (2017)
Megan H Wright, Christian Fetzer, Stephan A Sieber
Chemical Probes Unravel an Antimicrobial Defense Response Triggered by Binding of the Human Opioid Dynorphin to a Bacterial Sensor Kinase. Journal of the American Chemical Society 139 (17) (2017)

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Stephan A Sieber