Asier Unciti-Broceta

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 54

Top Venues

Nano letters

The Journal of experimental medicine

Nature communications

RSC medicinal chemistry

University of Edinburgh

Universidad de Granada (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Edinburgh Aug 01 2018

United Kingdom

Professor of Medicinal Chemistry :: Cancer Research UK Edinburgh Centre

University of Edinburgh - Jul 31 2018

United Kingdom

Reader in Medicinal Chemistry :: Cancer Research UK Edinburgh Centre

University of Edinburgh

United Kingdom

IGMM Academic Fellow :: Cancer Research UK Edinburgh Centre

Deliverics Ltd

United Kingdom

Chief Scientific Officer

University of Edinburgh

United Kingdom

Scottish Enterprise Research Fellow :: School of Chemistry

University of Edinburgh

United Kingdom

Postdoctoral Fellow :: School of Chemistry

Education History

Universidad de Granada

Spain

PHD :: Departamento de Química Farmacéutica

Publications

Maria Sancho-Albero, Victor Sebastian Cabeza, Ana M Perez-Lopez, Pilar Martín-Duque, Asier Unciti-Broceta, Jesús Santamaría
Extracellular Vesicles-Mediated Bio-Orthogonal Catalysis in Growing Tumors. Cells 13 (8) (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry 22 (10) (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry 22 (10) (2024)
Linlin Deng, Anjana Sathyan, Catherine Adam, Asier Unciti-Broceta, Victor Sebastian Cabeza, Anja R A Palmans
Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer's Microstructure. Nano letters 24 (7) (2024)
Linlin Deng, Anjana Sathyan, Catherine Adam, Asier Unciti-Broceta, Victor Sebastian Cabeza, Anja R A Palmans
Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer's Microstructure. Nano letters (2024)
Melissa van de L'Isle, Stephen Croke, Teresa Valero, Asier Unciti-Broceta
Development of Biocompatible Cu(I)-Microdevices for Bioorthogonal Uncaging and Click Reactions. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Linlin Deng, Anjana Sathyan, Catherine Adam, Asier Unciti-Broceta, Victor Sebastian Cabeza, Anja R A Palmans
Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer's Microstructure. Nano letters 24 (7) (2024)
Eleni Nestoros, Fabio de Moliner, Ferran Nadal-Bufi, Deborah Seah, M Carmen Ortega-Liebana, Zhiming Cheng, Sam Benson, Catherine Adam, Larissa Maierhofer, Kostiantyn Kozoriz, Jun-Seok Lee, Asier Unciti-Broceta, Marc Vendrell
Tuning singlet oxygen generation with caged organic photosensitizers. Nature communications 15 (1) (2024)
Eleni Nestoros, Fabio de Moliner, Ferran Nadal-Bufi, Deborah Seah, M Carmen Ortega-Liebana, Zhiming Cheng, Sam Benson, Catherine Adam, Larissa Maierhofer, Kostiantyn Kozoriz, Jun-Seok Lee, Asier Unciti-Broceta, Marc Vendrell
Tuning singlet oxygen generation with caged organic photosensitizers. Nature communications 15 (1) (2024)
Maria Sancho-Albero, Victor Sebastian Cabeza, Ana M Perez-Lopez, Pilar Martín-Duque, Asier Unciti-Broceta, Jesús Santamaría
Extracellular Vesicles-Mediated Bio-Orthogonal Catalysis in Growing Tumors. Cells 13 (8) (2024)
Maria Sancho-Albero, Victor Sebastian Cabeza, Ana M Perez-Lopez, Pilar Martín-Duque, Asier Unciti-Broceta, Jesús Santamaría
Extracellular Vesicles-Mediated Bio-Orthogonal Catalysis in Growing Tumors. Cells 13 (8) (2024)
Linlin Deng, Anjana Sathyan, Catherine Adam, Asier Unciti-Broceta, Victor Sebastian Cabeza, Anja R A Palmans
Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer's Microstructure. Nano letters 24 (7) (2024)
Josef Braun, M Carmen Ortega-Liebana, Asier Unciti-Broceta, Stephan A Sieber
A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces. Organic & biomolecular chemistry 22 (10) (2024)
Linlin Deng, Anjana Sathyan, Catherine Adam, Asier Unciti-Broceta, Victor Sebastian Cabeza, Anja R A Palmans
Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer's Microstructure. Nano letters 24 (7) (2024)
Melissa van de L'Isle, Stephen Croke, Teresa Valero, Asier Unciti-Broceta
Development of Biocompatible Cu(I)-Microdevices for Bioorthogonal Uncaging and Click Reactions. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (30) (2024)
Shaoqin Liu, Vincent M Rotello, Asier Unciti-Broceta, Hui Wei
Introduction to nanozymes. Journal of materials chemistry. B (2023)
Xue-Feng Li, Cigdem Selli, Han-Lin Zhou, Jian Cao, Shuiqing Wu, Ruo-Yu Ma, Ye Lu, Cheng-Bin Zhang, Bijie Xun, Alyson D Lam, Xiao-Cong Pang, Anu Fernando, Zeda Zhang, Asier Unciti-Broceta, Neil O Carragher, Prakash Ramachandran, Neil Cowan Henderson, Ling-Ling Sun, Hai-Yan Hu, Gui-Bo Li, Charles L Sawyers, Bin-Zhi Qian
Macrophages promote anti-androgen resistance in prostate cancer bone disease. The Journal of experimental medicine 220 (4) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters 23 (3) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters 23 (3) (2023)
Daniel J Baillache, Teresa Valero, Álvaro Lorente-Macías, David Jonathan Bennett, Richard J R Elliott, Neil O Carragher, Asier Unciti-Broceta
Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells. RSC medicinal chemistry 14 (12) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters (2023)
Xue-Feng Li, Cigdem Selli, Han-Lin Zhou, Jian Cao, Shuiqing Wu, Ruo-Yu Ma, Ye Lu, Cheng-Bin Zhang, Bijie Xun, Alyson D Lam, Xiao-Cong Pang, Anu Fernando, Zeda Zhang, Asier Unciti-Broceta, Neil O Carragher, Prakash Ramachandran, Neil Cowan Henderson, Ling-Ling Sun, Hai-Yan Hu, Gui-Bo Li, Charles L Sawyers, Bin-Zhi Qian
Macrophages promote anti-androgen resistance in prostate cancer bone disease. The Journal of experimental medicine 220 (4) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters 23 (3) (2023)
Xue-Feng Li, Cigdem Selli, Han-Lin Zhou, Jian Cao, Shuiqing Wu, Ruo-Yu Ma, Ye Lu, Cheng-Bin Zhang, Bijie Xun, Alyson D Lam, Xiao-Cong Pang, Anu Fernando, Zeda Zhang, Asier Unciti-Broceta, Neil O Carragher, Prakash Ramachandran, Neil Cowan Henderson, Ling-Ling Sun, Hai-Yan Hu, Gui-Bo Li, Charles L Sawyers, Bin-Zhi Qian
Macrophages promote anti-androgen resistance in prostate cancer bone disease. The Journal of experimental medicine 220 (4) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters 23 (3) (2023)
Daniel J Baillache, Teresa Valero, Álvaro Lorente-Macías, David Jonathan Bennett, Richard J R Elliott, Neil O Carragher, Asier Unciti-Broceta
Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells. RSC medicinal chemistry 14 (12) (2023)
Daniel J Baillache, Teresa Valero, Álvaro Lorente-Macías, David Jonathan Bennett, Richard J R Elliott, Neil O Carragher, Asier Unciti-Broceta
Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells. RSC medicinal chemistry 14 (12) (2023)
Xue-Feng Li, Cigdem Selli, Han-Lin Zhou, Jian Cao, Shuiqing Wu, Ruo-Yu Ma, Ye Lu, Cheng-Bin Zhang, Bijie Xun, Alyson D Lam, Xiao-Cong Pang, Anu Fernando, Zeda Zhang, Asier Unciti-Broceta, Neil O Carragher, Prakash Ramachandran, Neil Cowan Henderson, Ling-Ling Sun, Hai-Yan Hu, Gui-Bo Li, Charles L Sawyers, Bin-Zhi Qian
Macrophages promote anti-androgen resistance in prostate cancer bone disease. The Journal of experimental medicine 220 (4) (2023)
Xue-Feng Li, Cigdem Selli, Han-Lin Zhou, Jian Cao, Shuiqing Wu, Ruo-Yu Ma, Ye Lu, Cheng-Bin Zhang, Bijie Xun, Alyson D Lam, Xiao-Cong Pang, Anu Fernando, Zeda Zhang, Asier Unciti-Broceta, Neil O Carragher, Prakash Ramachandran, Neil Cowan Henderson, Ling-Ling Sun, Hai-Yan Hu, Gui-Bo Li, Charles L Sawyers, Bin-Zhi Qian
Macrophages promote anti-androgen resistance in prostate cancer bone disease. The Journal of experimental medicine 220 (4) (2023)
Xue-Feng Li, Cigdem Selli, Han-Lin Zhou, Jian Cao, Shuiqing Wu, Ruo-Yu Ma, Ye Lu, Cheng-Bin Zhang, Bijie Xun, Alyson D Lam, Xiao-Cong Pang, Anu Fernando, Zeda Zhang, Asier Unciti-Broceta, Neil O Carragher, Prakash Ramachandran, Neil Cowan Henderson, Ling-Ling Sun, Hai-Yan Hu, Gui-Bo Li, Charles L Sawyers, Bin-Zhi Qian
Macrophages promote anti-androgen resistance in prostate cancer bone disease. The Journal of experimental medicine 220 (4) (2023)
Vanessa Smer-Barreto, Andrea Quintanilla, Richard J R Elliott, John C Dawson, Jiugeng Sun, Víctor M Campa, Álvaro Lorente-Macías, Asier Unciti-Broceta, Neil O Carragher, Juan Carlos Acosta, Diego A Oyarzún
Discovery of senolytics using machine learning. Nature communications 14 (1) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters 23 (3) (2023)
Belén Rubio-Ruiz, Ana M Perez-Lopez, Laura Uson, M Carmen Ortega-Liebana, Teresa Valero, Manuel Arruebo, Jose L Hueso, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Nano letters 23 (3) (2023)
Shiao Y Chow, Asier Unciti-Broceta
Targeted Molecular Construct for Bioorthogonal Theranostics of PD-L1-Expressing Cancer Cells. JACS Au 2 (7) (2022)
Catherine Adam, Thomas L Bray, Ana M Perez-Lopez, Ee Hong Tan, Belén Rubio-Ruiz, Daniel J Baillache, Douglas R Houston, Mark J Salji, Hing Y Leung, Asier Unciti-Broceta
A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo . Journal of medicinal chemistry 65 (1) (2022)
Henry Beetham, Billie G C Griffith, Olga Murina, Alexander E P Loftus, David A Parry, Carolin Temps, Jayne Culley, Morwenna T Muir, Asier Unciti-Broceta, Andrew H Sims, Adam Byron, Valerie G Brunton
Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors. Cancer research 82 (4) (2022)
Cecilia C Ayala-Aguilera, Teresa Valero, Álvaro Lorente-Macías, Daniel J Baillache, Stephen Croke, Asier Unciti-Broceta
Small Molecule Kinase Inhibitor Drugs (1995-2021): Medical Indication, Pharmacology, and Synthesis. Journal of medicinal chemistry (2021)
M Carmen Ortega-Liebana, Nicola J Porter, Catherine Adam, Teresa Valero, Lloyd Hamilton, Dirk Sieger, Catherina G Becker, Asier Unciti-Broceta
Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (1) (2021)
Nieves Martinez-Peinado, Álvaro Lorente-Macías, Alejandro García-Salguero, Nuria Cortes-Serra, Ángel Fenollar-Collado, Albert Ros-Lucas, Joaquim Gascon, Maria Jesús Pinazo, Ignacio J Molina, Asier Unciti-Broceta, Juan J Díaz-Mochón, María José Pineda de Las Infantas Villatoro, Luis Izquierdo, Julio Alonso-Padilla
Novel Purine Chemotypes with Activity against Plasmodium falciparum and Trypanosoma cruzi. Pharmaceuticals (Basel, Switzerland) 14 (7) (2021)
M Carmen Ortega-Liebana, Nicola J Porter, Catherine Adam, Teresa Valero, Lloyd Hamilton, Dirk Sieger, Catherina G Becker, Asier Unciti-Broceta
Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics. Angewandte Chemie (International ed. in English) (2021)
Carolin Temps, Daniel Lietha, Emily R Webb, Xue-Feng Li, John C Dawson, Morwenna T Muir, Kenneth G Macleod, Teresa Valero, Alison F Munro, Rafael Contreras-Montoya, Juan Román Luque-Ortega, Craig Fraser, Henry Beetham, Christina Schoenherr, Maria Lopalco, Mark J Arends, Margaret C Frame, Bin-Zhi Qian, Valerie G Brunton, Neil O Carragher, Asier Unciti-Broceta
A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability. Cancer research 81 (21) (2021)
Joshua D G Leach, Nikola Vlahov, Petros K Tsantoulis, Rachel A Ridgway, Dustin J Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G Vázquez, David F Vincent, William James Faller, Michael C Hodder, Alexander Raven, Sigrid Fey, Arafath K Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, null null, Sander R van Hooff, David J Huels, Jan Paul Medema, Simon T Barry, Margaret C Frame, Asier Unciti-Broceta, Simon J Leedham, Gareth J Inman, Rene Jackstadt, Barry James Thompson, Andrew D Campbell, Sabine Tejpar, Owen James Sansom
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis. Nature communications 12 (1) (2021)
M Carmen Ortega-Liebana, Nicola J Porter, Catherine Adam, Teresa Valero, Lloyd Hamilton, Dirk Sieger, Catherina G Becker, Asier Unciti-Broceta
Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (1) (2021)
Victor Sebastian Cabeza, Maria Sancho-Albero, Manuel Arruebo, Ana M Perez-Lopez, Belén Rubio-Ruiz, Pilar Martin-Duque, Asier Unciti-Broceta, Jesús Santamaría
Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis. Nature protocols 16 (1) (2020)
Daniel J Baillache, Asier Unciti-Broceta
Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold. RSC medicinal chemistry 11 (10) (2020)
Ana M Perez-Lopez, Belén Rubio-Ruiz, Teresa Valero, Rafael Contreras-Montoya, Luis Álvarez de Cienfuegos, Victor Sebastian Cabeza, Jesús Santamaría, Asier Unciti-Broceta
Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet-Hydrogel Frameworks. Journal of medicinal chemistry 63 (17) (2020)
Harvey W Smith, Alison Hirukawa, Virginie Sanguin-Gendreau, Ipshita Nandi, Catherine R Dufour, Dongmei Zuo, Kristofferson Tandoc, Matthew Leibovitch, Salendra Singh, Jonathan P Rennhack, Matthew Swiatnicki, Cynthia Lavoie, Vasilios Papavasiliou, Carolin Temps, Neil O Carragher, Asier Unciti-Broceta, Paul Savage, Mark Basik, Vincent van Hoef, Ola Larsson, Caroline L Cooper, Ana Cristina Vargas Calderon, Jane Beith, Ewan Millar, Christina Selinger, Vincent Giguère, Morag Park, Lyndsay N Harris, Vinay Varadan, Eran R Andrechek, Sandra A O'Toole, Ivan Topisirovic, William J Muller
An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis. Nature communications 10 (1) (2019)
Samuel H Myers, Carolin Temps, Douglas R Houston, Valerie G Brunton, Asier Unciti-Broceta
Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening. Journal of medicinal chemistry 61 (5) (2018)
Belén Rubio-Ruiz, Ana M Pérez-López, Thomas L Bray, Martin Lee, Alan Serrels, Martín Prieto, Manuel Arruebo, Neil O Carragher, Victor Sebastian Cabeza, Asier Unciti-Broceta
High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy. ACS applied materials & interfaces 10 (4) (2018)
Thomas L Bray, Mark J Salji, Alessandro Brombin, Ana M Perez-Lopez, Belén Rubio-Ruiz, Laura C A Galbraith, E Elizabeth Patton, Hing Y Leung, Asier Unciti-Broceta
Bright insights into palladium-triggered local chemotherapy. Chemical science 9 (37) (2018)
Teresa Valero, Antonio Delgado-González, Juan Diego Unciti-Broceta, Victoria Cano-Cortés, Ana M Pérez-López, Asier Unciti-Broceta, Rosario M Sánchez Martín
Drug "Clicking" on Cell-Penetrating Fluorescent Nanoparticles for In Cellulo Chemical Proteomics. Bioconjugate chemistry 29 (9) (2018)
Catherine Adam, Ana M Perez-Lopez, Lloyd Hamilton, Belén Rubio-Ruiz, Thomas L Bray, Dirk Sieger, Paul M Brennan, Asier Unciti-Broceta
Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (63) (2018)
Ana M Pérez-López, Belén Rubio-Ruiz, Victor Sebastian Cabeza, Lloyd Hamilton, Catherine Adam, Thomas L Bray, Silvia Irusta, Paul M Brennan, Guy C Lloyd Jones, Dirk Sieger, Jesús Santamaría, Asier Unciti-Broceta
Gold-Triggered Uncaging Chemistry in Living Systems. Angewandte Chemie (International ed. in English) 56 (41) (2017)

Asier Unciti-Broceta.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Asier Unciti-Broceta