William McCoull

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 14

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular pharmaceutics

This page only lists publications with an associated author ORCID identifier.

Publications

Clare Thomson, Peter Barton, Erin Braybrooke, Nicola Colclough, Zhiqiang Dong, Laura Evans, Nicolas Floc'h, Carine Guérot, David Hargreaves, Puneet Khurana, Songlei Li, Xiuwei Li, Andrew Lister, William McCoull, Lisa McWilliams, Jonathan P Orme, Martin J Packer, Aisha M Swaih, Richard A Ward, Poppy Winlow, Yang Ye
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Journal of medicinal chemistry (2024)
Clare Thomson, Peter Barton, Erin Braybrooke, Nicola Colclough, Zhiqiang Dong, Laura Evans, Nicolas Floc'h, Carine Guérot, David Hargreaves, Puneet Khurana, Songlei Li, Xiuwei Li, Andrew Lister, William McCoull, Lisa McWilliams, Jonathan P Orme, Martin J Packer, Aisha M Swaih, Richard A Ward, Poppy Winlow, Yang Ye
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Journal of medicinal chemistry 67 (11) (2024)
Beth Williamson, Lindsay McMurray, Scott Boyd, Olga Collingwood, Neville McLean, Jon J Winter-Holt, Christina Chan, Aixiang Xue, William McCoull
Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems. Molecular pharmaceutics 19 (7) (2022)
Piotr Raubo, Rodrigo J Carbajo, William McCoull, Joanna Raubo, Morgan Thomas
Diversity-orientated synthesis of macrocyclic heterocycles using a double SNAr approach. Organic & biomolecular chemistry 19 (28) (2022)
Claire M Patterson, Srividya B Balachander, Iain Grant, Petar Pop-Damkov, Brian Kelly, William McCoull, Jeremy S Parker, Michael Giannis, Kathryn J Hill, Francis D Gibbons, Edward J Hennessy, Paul D Kemmitt, Alexander R Harmer, Sonya Gales, Stuart Purbrick, Sean Redmond, Matthew Skinner, Lorraine Graham, J Paul Secrist, Alwin G Schuller, Shenghua Wen, Ammar Adam, Corinne Reimer, Justin Cidado, Martin Wild, Eric Gangl, Stephen E Fawell, Jamal Saeh, Barry R Davies, David J Owen, Marianne B Ashford
Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapy. Communications biology 4 (1) (2021)
J Willem M Nissink, Sana Bazzaz, Carolyn Blackett, Matthew A Clark, Olga Collingwood, Jeremy S Disch, Diana Gikunju, Kristin Goldberg, John P Guilinger, Elizabeth Hardaker, Edward J Hennessy, Rachael Jetson, Anthony D Keefe, William McCoull, Lindsay McMurray, Allison Olszewski, Ross Overman, Alexander Pflug, Marian Preston, Philip B Rawlins, Emma Rivers, Marianne Schimpl, Paul Smith, Caroline Truman, Elizabeth Underwood, Juli Warwicker, Jon Winter-Holt, Simon Woodcock, Ying Zhang
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy. Journal of medicinal chemistry 64 (6) (2021)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Correction to "Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles". Journal of medicinal chemistry 64 (5) (2021)
William McCoull, Scott Boyd, Martin R Brown, Muireann Coen, Olga Collingwood, Nichola L Davies, Ann Doherty, Gary Fairley, Kristin Goldberg, Elizabeth Hardaker, Guang He, Edward J Hennessy, Philip Hopcroft, George Hodgson, Anne Jackson, Xiefeng Jiang, Ankur Karmokar, Anne-Laure Lainé, Nicola Lindsay, Yumeng Mao, Roshini Markandu, Lindsay McMurray, Neville McLean, Lorraine Mooney, Helen Musgrove, J Willem M Nissink, Alexander Pflug, Venkatesh Pilla Reddy, Philip B Rawlins, Emma Rivers, Marianne Schimpl, Graham F Smith, Sharon Tentarelli, Jon Travers, Robert I Troup, Josephine Walton, Cheng Wang, Stephen Wilkinson, Beth Williamson, Jon Winter-Holt, Dejian Yang, Yuting Zheng, Qianxiu Zhu, Paul D Smith
Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. Journal of medicinal chemistry 64 (18) (2021)
Srividya B Balachander, Steven W Criscione, Kate F Byth, Justin Cidado, Ammar Adam, Paula Lewis, Terry Macintyre, Shenghua Wen, Deborah Lawson, Kathleen Burke, Tristan Lubinski, Jeffrey W Tyner, Stephen E Kurtz, Shannon K McWeeney, Jeffrey Varnes, R Bruce Diebold, Thomas Gero, Stephanos Ioannidis, Edward J Hennessy, William McCoull, Jamal C Saeh, Areya Tabatabai, Omid Tavana, Nancy Su, Alwin Schuller, Mathew J Garnett, Patricia Jaaks, Elizabeth A Coker, Gareth Peter Gregory, Andrea Newbold, Ricky W Johnstone, Eric Gangl, Martin Wild, Michael Zinda, J Paul Secrist, Barry R Davies, Stephen E Fawell, Francis D Gibbons
AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-xL, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (24) (2020)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles. Journal of medicinal chemistry 62 (21) (2019)
William McCoull, Tony Cheung, Erica Anderson, Peter Barton, Jonathan Burgess, Kate Byth, Qing Cao, M Paola Castaldi, Huawei Chen, Elisabetta Chiarparin, Rodrigo J Carbajo, Erin Code, Suzanna Cowan, Paul R Davey, Andrew D Ferguson, Shaun Fillery, Nathan O Fuller, Ning Gao, David Hargreaves, Martin R Howard, Jun Hu, Aarti Kawatkar, Paul D Kemmitt, Elisabetta Leo, Daniel M Molina, Nichole O'Connell, Philip Petteruti, Timothy Rasmusson, Piotr Raubo, Philip B Rawlins, Piero Ricchiuto, Graeme R Robb, Monica Schenone, Michael J Waring, Michael Zinda, Stephen Fawell, David M Wilson
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6. ACS chemical biology 13 (11) (2018)
William McCoull, Andrew Bailey, Peter Barton, Alan M Birch, Alastair J H Brown, Hayley S Butler, Scott Boyd, Roger J Butlin, Ben Chappell, Paul Clarkson, Shelley Collins, Robert M D Davies, Anne Ertan, Clare D Hammond, Jane L Holmes, Carol Lenaghan, Anita Midha, Pablo Morentin-Gutierrez, Jane E Moore, Piotr Raubo, Graeme Robb
Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy. Journal of medicinal chemistry 60 (7) (2017)
William McCoull, Roman D Abrams, Erica Anderson, Kevin Blades, Peter Barton, Matthew Box, Jonathan Burgess, Kate Byth, Qing Cao, Claudio Chuaqui, Rodrigo J Carbajo, Tony Cheung, Erin Code, Andrew D Ferguson, Shaun Fillery, Nathan O Fuller, Eric Gangl, Ning Gao, Matthew Grist, David Hargreaves, Martin R Howard, Jun Hu, Paul D Kemmitt, Jennifer E Nelson, Nichole O'Connell, D Bryan Prince, Piotr Raubo, Philip B Rawlins, Graeme R Robb, Junjie Shi, Michael J Waring, David Whittaker, Marta Wylot, Xiahui Zhu
Correction to Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. Journal of medicinal chemistry 60 (14) (2017)
William McCoull, Roman D Abrams, Erica Anderson, Kevin Blades, Peter Barton, Matthew Box, Jonathan Burgess, Kate Byth, Qing Cao, Claudio Chuaqui, Rodrigo J Carbajo, Tony Cheung, Erin Code, Andrew D Ferguson, Shaun Fillery, Nathan O Fuller, Eric Gangl, Ning Gao, Matthew Grist, David Hargreaves, Martin R Howard, Jun Hu, Paul D Kemmitt, Jennifer E Nelson, Nichole O'Connell, D Bryan Prince, Piotr Raubo, Philip B Rawlins, Graeme R Robb, Junjie Shi, Michael J Waring, David Whittaker, Marta Wylot, Xiahui Zhu
Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. Journal of medicinal chemistry 60 (10) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

William McCoull