Jeffrey W Johannes (Jeffrey Johannes)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Topics

Breast Cancer Cells

Induced Apoptosis

Tyrosine Kinase

Top Venues

Science signaling

Journal of medicinal chemistry

Clinical cancer research : an official journal of the American Association for Cancer Research

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Emily C Erickson, Inchul You, Grace E Perry, Aurélien J F Dugourd, Katherine Aleisha Donovan, Claire Crafter, Jeffrey W Johannes, Stuart Charles Williamson, Jennifer I Moss, Susana Ros, Robert E Ziegler, Simon T Barry, Eric S Fischer, Nathanael S Gray, Ralitsa R Madsen, Alex Toker
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation. Science signaling 17 (825) (2024)
Emily C Erickson, Inchul You, Grace E Perry, Aurélien J F Dugourd, Katherine Aleisha Donovan, Claire Crafter, Jeffrey W Johannes, Stuart Charles Williamson, Jennifer I Moss, Susana Ros, Robert E Ziegler, Simon T Barry, Eric S Fischer, Nathanael S Gray, Ralitsa R Madsen, Alex Toker
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation. Science signaling 17 (825) (2024)
Emily C Erickson, Inchul You, Grace E Perry, Aurélien J F Dugourd, Katherine Aleisha Donovan, Claire Crafter, Jeffrey W Johannes, Stuart Charles Williamson, Jennifer I Moss, Susana Ros, Robert E Ziegler, Simon T Barry, Eric S Fischer, Nathanael S Gray, Ralitsa R Madsen, Alex Toker
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation. Science signaling 17 (825) (2024)
Emily C Erickson, Inchul You, Grace E Perry, Aurélien J F Dugourd, Katherine Aleisha Donovan, Claire Crafter, Jeffrey W Johannes, Stuart Charles Williamson, Jennifer I Moss, Susana Ros, Robert E Ziegler, Simon T Barry, Eric S Fischer, Nathanael S Gray, Ralitsa R Madsen, Alex Toker
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation. Science signaling 17 (825) (2024)
Cameron H Chrisman, Max Kudisch, Katherine O Puffer, Trevor K Stewart, Yisrael M L Lamb, Chern-Hooi Lim, Randolph A Escobar, Pall Thordarson, Jeffrey W Johannes, Garret M Miyake
Halide Noninnocence and Direct Photoreduction of Ni(II) Enables Coupling of Aryl Chlorides in Dual Catalytic, Carbon-Heteroatom Bond-Forming Reactions. Journal of the American Chemical Society (2023)
Cameron H Chrisman, Max Kudisch, Katherine O Puffer, Trevor K Stewart, Yisrael M L Lamb, Chern-Hooi Lim, Randolph A Escobar, Pall Thordarson, Jeffrey W Johannes, Garret M Miyake
Halide Noninnocence and Direct Photoreduction of Ni(II) Enables Coupling of Aryl Chlorides in Dual Catalytic, Carbon-Heteroatom Bond-Forming Reactions. Journal of the American Chemical Society (2023)
Anna D Staniszewska, Domenic Pilger, Sonja J Gill, Kunzah Jamal, Natacha Bohin, Sofia Guzzetti, Jacob A Gordon, Gregory Hamm, Gill Mundin, Giuditta Illuzzi, Andy Pike, Lisa McWilliams, Gareth A Maglennon, Jonathan Rose, Glen Hawthorne, Miguel A Cortés González, Christer Halldin, Peter Johnström, Magnus Schou, Susan E Critchlow, Stephen E Fawell, Jeffrey W Johannes, Elisabetta Leo, Barry R Davies, Sabina Cosulich, Jann N Sarkaria, Lenka Oplustil O'Connor, Petra Hamerlik
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Christopher S Gravatt, Jeffrey W Johannes, Eric R King, Avipsa Ghosh
Photoredox-Mediated, Nickel-Catalyzed Trifluoromethylthiolation of Aryl and Heteroaryl Iodides. The Journal of organic chemistry 87 (14) (2022)
Giuditta Illuzzi, Anna D Staniszewska, Sonja J Gill, Andy Pike, Lisa McWilliams, Susan E Critchlow, Anna Cronin, Stephen E Fawell, Glen Hawthorne, Kunzah Jamal, Jeffrey W Johannes, Emilyanne Leonard, Ruth Macdonald, Gareth A Maglennon, Jenni Nikkilä, Lenka Oplustil O'Connor, Aaron Smith, Harriet Southgate, Joanne Wilson, James W T Yates, Sabina Cosulich, Elisabetta Leo
Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (21) (2022)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Correction to "Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles". Journal of medicinal chemistry 64 (5) (2021)
Jeffrey W Johannes, Amber Balazs, Derek Barratt, Michal Bista, Matthew D Chuba, Sabina Cosulich, Susan E Critchlow, Sébastien L Degorce, Paolo Di Fruscia, Scott D Edmondson, Kevin Embrey, Stephen Fawell, Avipsa Ghosh, Sonja J Gill, Anders Gunnarsson, Sudhir M Hande, Tom D Heightman, Paul Hemsley, Giuditta Illuzzi, Jordan Lane, Carrie Larner, Elisabetta Leo, Lina Liu, Andrew Madin, Scott Martin, Lisa McWilliams, Mark J O'Connor, Jonathan P Orme, Fiona Pachl, Martin J Packer, Xiaohui Pei, Andrew Pike, Marianne Schimpl, Hongyao She, Anna D Staniszewska, Verity Talbot, Elizabeth Underwood, Jeffrey G Varnes, Lin Xue, Tieguang Yao, Ke Zhang, Andrew X Zhang, Xiaolan Zheng
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs. Journal of medicinal chemistry 64 (19) (2021)
Randolph A Escobar, Jeffrey W Johannes
Reductive Radical Conjugate Addition of Alkyl Electrophiles Catalyzed by a Cobalt/Iridium Photoredox System. Organic letters 23 (15) (2021)
Randolph A Escobar, Jeffrey W Johannes
A Unified and Practical Method for Carbon-Heteroatom Cross-Coupling using Nickel/Photo Dual Catalysis. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (23) (2020)
Thomas J Struble, Juan C Alvarez, Scott P Brown, Milan Chytil, Justin S Cisar, Renee L DesJarlais, Ola Engkvist, Scott A Frank, Daniel R Greve, Daniel J Griffin, Xinjun Hou, Jeffrey W Johannes, Constantine Kreatsoulas, Brian Lahue, Miriam Mathea, Georg Mogk, Christos A Nicolaou, Andrew D Palmer, Daniel J Price, Richard I Robinson, Sebastian Salentin, Li Xing, Tommi S Jaakkola, William H Green, Regina Barzilay, Connor W Coley, Klavs F Jensen
Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis. Journal of medicinal chemistry 63 (16) (2020)
Ryan T Howard, Paul Hemsley, Philip Petteruti, Charlie N Saunders, Javier A Molina Bermejo, James S Scott, Jeffrey W Johannes, Edward William Tate
Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors. ACS chemical biology 15 (2) (2020)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles. Journal of medicinal chemistry 62 (21) (2019)
Adriana E Tron, Matthew A Belmonte, Ammar Adam, Brian M Aquila, Lawrence H Boise, Elisabetta Chiarparin, Justin Cidado, Kevin J Embrey, Eric Gangl, Francis D Gibbons, Gareth Peter Gregory, David Hargreaves, J Adam Hendricks, Jeffrey W Johannes, Ricky W Johnstone, Steven L Kazmirski, Jason G Kettle, Michelle L Lamb, Shannon M Matulis, Ajay K Nooka, Martin J Packer, Bo Peng, Philip B Rawlins, Daniel W Robbins, Alwin G Schuller, Nancy Su, Wenzhan Yang, Qing Ye, Xiaolan Zheng, J Paul Secrist, Edwin A Clark, David M Wilson, Stephen E Fawell, Alexander W Hird
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nature communications 9 (1) (2018)
Zebin Wang, Shaun E Grosskurth, Tony Cheung, Philip Petteruti, Jingwen Zhang, Xin Wang, Wenxian Wang, Farzin Gharahdaghi, Jiaquan Wu, Nancy Su, Ryan T Howard, Michele Mayo, Dan Widzowski, David A Scott, Jeffrey W Johannes, Michelle L Lamb, Deborah Lawson, Jonathan R Dry, Paul D Lyne, Edward William Tate, Michael Zinda, Keith Mikule, Stephen E Fawell, Corinne Reimer, Huawei Chen
Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer. Cancer research 78 (23) (2018)
Jeffrey W Johannes, Christopher R Denz, Nancy Su, Allan Wu, Anna C Impastato, Scott Mlynarski, Jeffrey G Varnes, D Bryan Prince, Justin Cidado, Ning Gao, Malcolm Haddrick, Natalie H Jones, Shaobin Li, Xiuwei Li, Yang Liu, Toan B Nguyen, Nichole O'Connell, Emma Rivers, Daniel W Robbins, Ronald Tomlinson, Tieguang Yao, Xiahui Zhu, Andrew D Ferguson, Michelle L Lamb, John I Manchester, Sylvie Guichard
Structure-Based Design of Selective Noncovalent CDK12 Inhibitors. ChemMedChem 13 (3) (2018)