Michelle L Lamb

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 22

Top Venues

Journal of medicinal chemistry

ACS medicinal chemistry letters

Cancer research

ACS chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, David Hargreaves, Alexander G Milbradt, Mark J Bostock, Samiyah Ahmed, Kevin Beaumont, Tony Cheung, Sylvain Demanze, Andrea Gohlke, Carine Guerot, Afreen Haider, Vasudev Kantae, Gregory W Kauffman, Olaf Kinzel, Lea Kupcova, Michael D Lainchbury, Michelle L Lamb, Leonardo Leon, Adeline Palisse, Claudia Sacchetto, R Ian Storer, Nancy Su, Clare Thomson, John Vales, Yunhua Chen, Xiaolong Hu
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors. Journal of medicinal chemistry (2024)
Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti, Christina Chan, Alex J Chinn, Erin Code, Patrick J Fricke, Kathryn A Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J Hughes, Meizhong Jin, Vasudev Kantae, Stefan L Kavanagh, Michelle L Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R Quinn, Iswarya Reddy, Graeme R Robb, Kevin J Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J Walsh, Jamie Ware, Iain D G Watson, Min-Wei Ye, Gail L Wrigley, Andrew X Zhang, Yun Zhang, Neil P Grimster
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. Journal of medicinal chemistry 67 (2) (2024)
Taylor R Quinn, Kathryn A Giblin, Clare Thomson, Jeffrey A Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P Grimster, Keishi Kohara, Michelle L Lamb, Lina Ma, Adelphe M Mfuh, Graeme R Robb, Kevin J Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J Hughes
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design. Journal of medicinal chemistry 67 (16) (2024)
Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti, Christina Chan, Alex J Chinn, Erin Code, Patrick J Fricke, Kathryn A Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J Hughes, Meizhong Jin, Vasudev Kantae, Stefan L Kavanagh, Michelle L Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R Quinn, Iswarya Reddy, Graeme R Robb, Kevin J Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J Walsh, Jamie Ware, Iain D G Watson, Min-Wei Ye, Gail L Wrigley, Andrew X Zhang, Yun Zhang, Neil P Grimster
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. Journal of medicinal chemistry (2024)
Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell, Silvia Bonomo, Andrew Brierley, Doyle J Cassar, Jared Freeman, Thomas E Hadfield, Lucas A Morrill, Rick Riemens, Sunil Sarda, Stefan Schiesser, Daniel Wiktelius, Samiyah Ahmed, Mark J Bostock, Ulf Börjesson, Claudia De Fusco, Carine Guerot, David Hargreaves, Sarah Hewitt, Michelle L Lamb, Nancy Su, Ryan Whatling, Matthew Wheeler, Jason G Kettle
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1. Journal of medicinal chemistry 67 (13) (2024)
Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell, Silvia Bonomo, Andrew Brierley, Doyle J Cassar, Jared Freeman, Thomas E Hadfield, Lucas A Morrill, Rick Riemens, Sunil Sarda, Stefan Schiesser, Daniel Wiktelius, Samiyah Ahmed, Mark J Bostock, Ulf Börjesson, Claudia De Fusco, Carine Guerot, David Hargreaves, Sarah Hewitt, Michelle L Lamb, Nancy Su, Ryan Whatling, Matthew Wheeler, Jason G Kettle
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1. Journal of medicinal chemistry 67 (13) (2024)
Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, David Hargreaves, Alexander G Milbradt, Samiyah Ahmed, Mark J Bostock, Carine Guerot, Andrea Gohlke, Olaf Kinzel, Michelle L Lamb, Nidhal Selmi, Christopher J Stubbs, Nancy Su, Qibin Su, Haiou Luo, Ting Xiong, Xiaoqian Zuo, Sana Bazzaz, Corey Bienstock, Paolo A Centrella, Kyle E Denton, Diana Gikunju, Marie-Aude Guié, John P Guilinger, Christopher Hupp, Anthony D Keefe, Takashi Satoh, Ying Zhang, Emma L Rivers
Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen. ACS medicinal chemistry letters 15 (6) (2024)
Simon C C Lucas, J Henry Blackwell, Ulf Börjesson, David Hargreaves, Alexander G Milbradt, Samiyah Ahmed, Mark J Bostock, Carine Guerot, Andrea Gohlke, Olaf Kinzel, Michelle L Lamb, Nidhal Selmi, Christopher J Stubbs, Nancy Su, Qibin Su, Haiou Luo, Ting Xiong, Xiaoqian Zuo, Sana Bazzaz, Corey Bienstock, Paolo A Centrella, Kyle E Denton, Diana Gikunju, Marie-Aude Guié, John P Guilinger, Christopher Hupp, Anthony D Keefe, Takashi Satoh, Ying Zhang, Emma L Rivers
Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen. ACS medicinal chemistry letters 15 (6) (2024)
Taylor R Quinn, Kathryn A Giblin, Clare Thomson, Jeffrey A Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P Grimster, Keishi Kohara, Michelle L Lamb, Lina Ma, Adelphe M Mfuh, Graeme R Robb, Kevin J Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J Hughes
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design. Journal of medicinal chemistry (2024)
Taylor R Quinn, Kathryn A Giblin, Clare Thomson, Jeffrey A Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P Grimster, Keishi Kohara, Michelle L Lamb, Lina Ma, Adelphe M Mfuh, Graeme R Robb, Kevin J Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J Hughes
Accelerated Discovery of Carbamate Cbl-b Inhibitors Using Generative AI Models and Structure-Based Drug Design. Journal of medicinal chemistry 67 (16) (2024)
Simon C C Lucas, Alexander G Milbradt, J Henry Blackwell, Silvia Bonomo, Andrew Brierley, Doyle J Cassar, Jared Freeman, Thomas E Hadfield, Lucas A Morrill, Rick Riemens, Sunil Sarda, Stefan Schiesser, Daniel Wiktelius, Samiyah Ahmed, Mark J Bostock, Ulf Börjesson, Claudia De Fusco, Carine Guerot, David Hargreaves, Sarah Hewitt, Michelle L Lamb, Nancy Su, Ryan Whatling, Matthew Wheeler, Jason G Kettle
Design of a Lead-Like Cysteine-Targeting Covalent Library and the Identification of Hits to Cys55 of Bfl-1. Journal of medicinal chemistry (2024)
Adelphe M Mfuh, Jeffrey A Boerth, Gayathri Bommakanti, Christina Chan, Alex J Chinn, Erin Code, Patrick J Fricke, Kathryn A Giblin, Andrea Gohlke, Catherine Hansel, Niresh Hariparsad, Samantha J Hughes, Meizhong Jin, Vasudev Kantae, Stefan L Kavanagh, Michelle L Lamb, Jordan Lane, Rachel Moore, Taranee Puri, Taylor R Quinn, Iswarya Reddy, Graeme R Robb, Kevin J Robbins, Miguel Gancedo Rodrigo, Marianne Schimpl, Baljinder Singh, Meha Singh, Haoran Tang, Clare Thomson, Jarrod J Walsh, Jamie Ware, Iain D G Watson, Min-Wei Ye, Gail L Wrigley, Andrew X Zhang, Yun Zhang, Neil P Grimster
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. Journal of medicinal chemistry 67 (2) (2024)
Iacovos N Michaelides, Gavin W Collie, Ulf Börjesson, Christina Vasalou, Omar Alkhatib, Louise Barlind, Tony Cheung, Ian L Dale, Kevin J Embrey, Edward J Hennessy, Puneet Khurana, Cheryl M Koh, Michelle L Lamb, Jianming Liu, Thomas A Moss, Daniel J O'Neill, Christopher Phillips, Joseph Shaw, Arjan Snijder, R Ian Storer, Christopher J Stubbs, Fujin Han, Chengzhi Li, Jingchuan Qiao, Dong-Qing Sun, Jingwen Wang, Peng Wang, Wenzhen Yang
Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor. Journal of medicinal chemistry (2023)
Jeffrey A Boerth, Alex J Chinn, Marianne Schimpl, Gayathri Bommakanti, Christina Chan, Erin L Code, Kathryn A Giblin, Andrea Gohlke, Catherine S Hansel, Meizhong Jin, Stefan L Kavanagh, Michelle L Lamb, Jordan S Lane, Carrie J B Larner, Adelphe M Mfuh, Rachel K Moore, Taranee Puri, Taylor R Quinn, Minwei Ye, Kevin J Robbins, Miguel Gancedo Rodrigo, Haoran Tang, Jarrod Walsh, Jamie Ware, Gail L Wrigley, Iswarya Karapa Reddy, Yun Zhang, Neil P Grimster
Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity. ACS medicinal chemistry letters 14 (12) (2023)
Jeffrey A Boerth, Alex J Chinn, Marianne Schimpl, Gayathri Bommakanti, Christina Chan, Erin L Code, Kathryn A Giblin, Andrea Gohlke, Catherine S Hansel, Meizhong Jin, Stefan L Kavanagh, Michelle L Lamb, Jordan S Lane, Carrie J B Larner, Adelphe M Mfuh, Rachel K Moore, Taranee Puri, Taylor R Quinn, Minwei Ye, Kevin J Robbins, Miguel Gancedo Rodrigo, Haoran Tang, Jarrod Walsh, Jamie Ware, Gail L Wrigley, Iswarya Karapa Reddy, Yun Zhang, Neil P Grimster
Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity. ACS medicinal chemistry letters 14 (12) (2023)
J Adam Hendricks, Nigel Beaton, Alexey Chernobrovkin, Eric Miele, Ghaith M Hamza, Piero Ricchiuto, Ronald C Tomlinson, Tomas Friman, Cassandra Borenstain, Bernard Barlaam, Sudhir Hande, Michelle L Lamb, Chris De Savi, Rick Davies, Martin Main, Joakim Hellner, Kristina Beeler, Yuehan Feng, Roland Bruderer, Lukas Reiter, Daniel Martinez Molina, M Paola Castaldi
Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics Methods. ACS chemical biology 17 (1) (2021)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Correction to "Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles". Journal of medicinal chemistry 64 (5) (2021)
Bernard Barlaam, Chris De Savi, Allan Dishington, Lisa Drew, Andrew D Ferguson, Douglas Ferguson, Chungang Gu, Sudhir Hande, Lorraine Hassall, Janet Hawkins, Alexander W Hird, Jane Holmes, Michelle L Lamb, Andrew S Lister, Thomas M McGuire, Jane E Moore, Nichole O'Connell, Anil Patel, Kurt G Pike, Ujjal Sarkar, Wenlin Shao, Darren Stead, Jeffrey G Varnes, Melissa M Vasbinder, Lei Wang, Liangwei Wu, Lin Xue, Bin Yang, Tieguang Yao
Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement. Journal of medicinal chemistry 64 (20) (2021)
Bernard Barlaam, Robert Casella, Justin Cidado, Calum Cook, Chris De Savi, Allan Dishington, Craig S Donald, Lisa Drew, Andrew D Ferguson, Douglas Ferguson, Steve Glossop, Tyler Grebe, Chungang Gu, Sudhir Hande, Janet Hawkins, Alexander W Hird, Jane Holmes, James Horstick, Yun Jiang, Michelle L Lamb, Thomas M McGuire, Jane E Moore, Nichole O'Connell, Andy Pike, Kurt G Pike, Theresa Proia, Bryan Roberts, Maryann San Martin, Ujjal Sarkar, Wenlin Shao, Darren Stead, Neil Sumner, Kumar Thakur, Melissa M Vasbinder, Jeffrey G Varnes, Jianyan Wang, Lei Wang, Dedong Wu, Liangwei Wu, Bin Yang, Tieguang Yao
Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies. Journal of medicinal chemistry 63 (24) (2020)
Amber Y S Balazs, Rodrigo J Carbajo, Nichola L Davies, Yu Dong, Alexander W Hird, Jeffrey W Johannes, Michelle L Lamb, William McCoull, Piotr Raubo, Graeme R Robb, Martin J Packer, Elisabetta Chiarparin
Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles. Journal of medicinal chemistry 62 (21) (2019)
Adriana E Tron, Matthew A Belmonte, Ammar Adam, Brian M Aquila, Lawrence H Boise, Elisabetta Chiarparin, Justin Cidado, Kevin J Embrey, Eric Gangl, Francis D Gibbons, Gareth Peter Gregory, David Hargreaves, J Adam Hendricks, Jeffrey W Johannes, Ricky W Johnstone, Steven L Kazmirski, Jason G Kettle, Michelle L Lamb, Shannon M Matulis, Ajay K Nooka, Martin J Packer, Bo Peng, Philip B Rawlins, Daniel W Robbins, Alwin G Schuller, Nancy Su, Wenzhan Yang, Qing Ye, Xiaolan Zheng, J Paul Secrist, Edwin A Clark, David M Wilson, Stephen E Fawell, Alexander W Hird
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nature communications 9 (1) (2018)
Zebin Wang, Shaun E Grosskurth, Tony Cheung, Philip Petteruti, Jingwen Zhang, Xin Wang, Wenxian Wang, Farzin Gharahdaghi, Jiaquan Wu, Nancy Su, Ryan T Howard, Michele Mayo, Dan Widzowski, David A Scott, Jeffrey W Johannes, Michelle L Lamb, Deborah Lawson, Jonathan R Dry, Paul D Lyne, Edward William Tate, Michael Zinda, Keith Mikule, Stephen E Fawell, Corinne Reimer, Huawei Chen
Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer. Cancer research 78 (23) (2018)

Michelle L Lamb.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Michelle L Lamb