Andrew Owen (A Owen)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 63

Top Topics

Respiratory Syndrome Coronavirus

Hiv Infected Patients

Top Venues

bioRxiv : the preprint server for biology

The Journal of antimicrobial chemotherapy

Microbiology spectrum

This page only lists publications with an associated author ORCID identifier.

Publications

Lee Tatham, Anja Kipar, Jo Sharp, Edyta Kijak, Joanne Herriott, Megan Neary, Helen Box, Eduardo Gallardo Toledo, Anthony Valentijn, Helen Cox, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kumar Reddy Rajoli, Steven P Rannard, James P Stewart, Andrew Owen
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiology spectrum (2024)
Jordan J Clark, Rebekah Penrice-Randal, Parul Sharma, Xiaofeng Dong, Shaun H Pennington, Amy E Marriott, Stefano Colombo, Andrew Davidson, Maia Kavanagh Williamson, David A Matthews, Lance C W Turtle, Tessa Prince, Grant L Hughes, Edward I Patterson, Ghada Shawli, Daniele F Mega, Krishanthi Subramaniam, Joanne Sharp, Joseph D Turner, Giancarlo A Biagini, Andrew Owen, Anja Kipar, Julian A Hiscox, James P Stewart
Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19. Viruses 16 (6) (2024)
Lee Tatham, Anja Kipar, Jo Sharp, Edyta Kijak, Joanne Herriott, Megan Neary, Helen Box, Eduardo Gallardo Toledo, Anthony Valentijn, Helen Cox, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kumar Reddy Rajoli, Steven P Rannard, James P Stewart, Andrew Owen
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiology spectrum (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19. bioRxiv : the preprint server for biology (2024)
Lee Tatham, Anja Kipar, Jo Sharp, Edyta Kijak, Joanne Herriott, Megan Neary, Helen Box, Eduardo Gallardo Toledo, Anthony Valentijn, Helen Cox, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kumar Reddy Rajoli, Steven P Rannard, James P Stewart, Andrew Owen
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiology spectrum (2024)
Daniel Kiiza, Danial Rostami-Hochaghan, Yussif Alhassan, Kay Seden, Helen Reynolds, Julian P Kaboggoza, Miriam Taegtmeyer, Tao Chen, Elizabeth Challenger, Thokozile Malaba, Duolao Wang, Laura Else, Faye Hern, Jo Sharp, Megan Neary, Sujan Dilly Penchala, Catriona Waitt, Catherine Orrell, Angela Colbers, Landon Myer, Andrew Owen, Steve Rannard, Saye H Khoo, Mohammed Lamorde
Clinical, pharmacological, and qualitative characterization of drug-drug interactions in pregnant women initiating HIV therapy in Sub-Saharan Africa. The Journal of antimicrobial chemotherapy (2024)
Daniel Kiiza, Danial Rostami-Hochaghan, Yussif Alhassan, Kay Seden, Helen Reynolds, Julian P Kaboggoza, Miriam Taegtmeyer, Tao Chen, Elizabeth Challenger, Thokozile Malaba, Duolao Wang, Laura Else, Faye Hern, Jo Sharp, Megan Neary, Sujan Dilly Penchala, Catriona Waitt, Catherine Orrell, Angela Colbers, Landon Myer, Andrew Owen, Steve Rannard, Saye H Khoo, Mohammed Lamorde
Clinical, pharmacological, and qualitative characterization of drug-drug interactions in pregnant women initiating HIV therapy in Sub-Saharan Africa. The Journal of antimicrobial chemotherapy 79 (9) (2024)
Lee Tatham, Anja Kipar, Jo Sharp, Edyta Kijak, Joanne Herriott, Megan Neary, Helen Box, Eduardo Gallardo Toledo, Anthony Valentijn, Helen Cox, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kumar Reddy Rajoli, Steven P Rannard, James P Stewart, Andrew Owen
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiology spectrum 12 (8) (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19. bioRxiv : the preprint server for biology (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19. bioRxiv : the preprint server for biology (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19. bioRxiv : the preprint server for biology (2024)
Jordan J Clark, Rebekah Penrice-Randal, Parul Sharma, Xiaofeng Dong, Shaun H Pennington, Amy E Marriott, Stefano Colombo, Andrew Davidson, Maia Kavanagh Williamson, David A Matthews, Lance C W Turtle, Tessa Prince, Grant L Hughes, Edward I Patterson, Ghada Shawli, Daniele F Mega, Krishanthi Subramaniam, Joanne Sharp, Joseph D Turner, Giancarlo A Biagini, Andrew Owen, Anja Kipar, Julian A Hiscox, James P Stewart
Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19. Viruses 16 (6) (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in infected and immune suppressed mice. bioRxiv : the preprint server for biology (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19. bioRxiv : the preprint server for biology (2024)
Jordan J Clark, Rebekah Penrice-Randal, Parul Sharma, Xiaofeng Dong, Shaun H Pennington, Amy E Marriott, Stefano Colombo, Andrew Davidson, Maia Kavanagh Williamson, David A Matthews, Lance C W Turtle, Tessa Prince, Grant L Hughes, Edward I Patterson, Ghada Shawli, Daniele F Mega, Krishanthi Subramaniam, Joanne Sharp, Joseph D Turner, Giancarlo A Biagini, Andrew Owen, Anja Kipar, Julian A Hiscox, James P Stewart
Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19. Viruses 16 (6) (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in infected and immune suppressed mice. bioRxiv : the preprint server for biology (2024)
Lee Tatham, Anja Kipar, Jo Sharp, Edyta Kijak, Joanne Herriott, Megan Neary, Helen Box, Eduardo Gallardo Toledo, Anthony Valentijn, Helen Cox, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kumar Reddy Rajoli, Steven P Rannard, James P Stewart, Andrew Owen
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case. Microbiology spectrum 12 (8) (2024)
Rebekah Penrice-Randal, Eleanor G Bentley, Parul Sharma, Adam Kirby, I'ah Donovan-Banfield, Anja Kipar, Daniele F Mega, Chloe Bramwell, Joanne Sharp, Andrew Owen, Julian A Hiscox, James P Stewart
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in infected and immune suppressed mice. bioRxiv : the preprint server for biology (2024)
Simon De Neck, Rebekah Penrice-Randal, Jordan J Clark, Parul Sharma, Eleanor G Bentley, Adam Kirby, Daniele F Mega, Ximeng Han, Andrew Owen, Julian A Hiscox, James P Stewart, Anja Kipar
The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections. Viruses 15 (8) (2023)
Victoria A Balta, Deborah Stiffler, Abeer Sayeed, Abhai K Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P Bakshi, Amanda G Dziedzic, Anne E Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A Canonizado, Alexis Mann, Andrew Owen, David J Sullivan, Sean T Prigge, Photini Sinnis, Theresa A Shapiro
Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes. bioRxiv : the preprint server for biology (2023)
Paul Curley, James J Hobson, Neill J Liptrott, Edward Makarov, Amer Al-Khouja, Lee Tatham, Christopher A W David, Helen Box, Megan Neary, Joanne Sharp, Henry Pertinez, David Meyers, Charles Flexner, Caren L Freel Meyers, Larisa Y Poluektova, Steve Rannard, Andrew Owen
Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations. Pharmaceutics 15 (7) (2023)
Victoria A Balta, Deborah Stiffler, Abeer Sayeed, Abhai K Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P Bakshi, Amanda G Dziedzic, Anne E Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A Canonizado, Alexis Mann, Andrew Owen, David J Sullivan, Sean T Prigge, Photini Sinnis, Theresa A Shapiro
Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes. bioRxiv : the preprint server for biology (2023)
Hannah Kinvig, Rajith Kumar Reddy Rajoli, Henry Pertinez, Lalitkumar K Vora, Fabiana Volpe-Zanutto, Ryan F Donelly, Steven P Rannard, Charles Flexner, Marco Siccardi, Andrew Owen
Physiologically Based Pharmacokinetic Modelling of Cabotegravir Microarray Patches in Rats and Humans. Pharmaceutics 15 (12) (2023)
Victoria A Balta, Deborah Stiffler, Abeer Sayeed, Abhai K Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P Bakshi, Amanda G Dziedzic, Anne E Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A Canonizado, Alexis Mann, Andrew Owen, David J Sullivan, Sean T Prigge, Photini Sinnis, Theresa A Shapiro
Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito. Nature communications 14 (1) (2023)
Victoria A Balta, Deborah Stiffler, Abeer Sayeed, Abhai K Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P Bakshi, Amanda G Dziedzic, Anne E Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A Canonizado, Alexis Mann, Andrew Owen, David J Sullivan, Sean T Prigge, Photini Sinnis, Theresa A Shapiro
Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes. bioRxiv : the preprint server for biology (2023)
Hannah Kinvig, Rajith Kumar Reddy Rajoli, Henry Pertinez, Lalitkumar K Vora, Fabiana Volpe-Zanutto, Ryan F Donelly, Steven P Rannard, Charles Flexner, Marco Siccardi, Andrew Owen
Physiologically Based Pharmacokinetic Modelling of Cabotegravir Microarray Patches in Rats and Humans. Pharmaceutics 15 (12) (2023)
Megan Neary, Joanne Sharp, Eduardo Gallardo-Toledo, Joanne Herriott, Edyta Kijak, Chloe Bramwell, Helen Cox, Lee Tatham, Helen Box, Paul Curley, Usman Arshad, Rajith K R Rajoli, Henry Pertinez, Anthony Valentijn, Kevin Dhaliwal, Frank McCaughan, James J Hobson, Steve Rannard, Anja Kipar, James P Stewart, Andrew Owen
Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters. Viruses 15 (8) (2023)
Bozana Obradovic, Owain Roberts, Andrew Owen, Ivana Milošević, Natasa Milic, Jovan T Ranin, Gordana Dragovic
Expression of CYP2B6 Enzyme in Human Liver Tissue of HIV and HCV Patients. Medicina (Kaunas, Lithuania) 59 (7) (2023)
Hannah Kinvig, Rajith Kumar Reddy Rajoli, Henry Pertinez, Lalitkumar K Vora, Fabiana Volpe-Zanutto, Ryan F Donelly, Steven P Rannard, Charles Flexner, Marco Siccardi, Andrew Owen
Physiologically Based Pharmacokinetic Modelling of Cabotegravir Microarray Patches in Rats and Humans. Pharmaceutics 15 (12) (2023)
Helen J Box, Joanne Sharp, Shaun H Pennington, Edyta Kijak, Lee Tatham, Claire H Caygill, Rose C Lopeman, Laura N Jeffreys, Joanne Herriott, Megan Neary, Anthony Valentijn, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kumar Reddy Rajoli, Dirk Jochmans, Laura Vangeel, Johan Neyts, Eric Chatelain, Fanny Escudie, Ivan Scandale, Steve Rannard, James P Stewart, Giancarlo A Biagini, Andrew Owen
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters. The Journal of antimicrobial chemotherapy (2023)
Eduardo Gallardo-Toledo, Megan Neary, Joanne Sharp, Joanne Herriott, Edyta Kijak, Chloe Bramwell, Paul Curley, Usman Arshad, Henry Pertinez, Rajith Kumar Reddy Rajoli, Anthony Valentijn, Helen Cox, Lee Tatham, Anja Kipar, James P Stewart, Andrew Owen
Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters. Viruses 15 (11) (2023)
Victoria A Balta, Deborah Stiffler, Abeer Sayeed, Abhai K Tripathi, Rubayet Elahi, Godfree Mlambo, Rahul P Bakshi, Amanda G Dziedzic, Anne E Jedlicka, Elizabeth Nenortas, Keyla Romero-Rodriguez, Matthew A Canonizado, Alexis Mann, Andrew Owen, David J Sullivan, Sean T Prigge, Photini Sinnis, Theresa A Shapiro
Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes. bioRxiv : the preprint server for biology (2023)
Katherine U Gaynor, Marina Vaysburd, Maximilian A J Harman, Anna Albecka, Phillip Jeffrey, Paul Beswick, Guido Papa, Liuhong Chen, Donna L Mallery, Brian McGuinness, Katerine Van Rietschoten, Steven Stanway, Paul D Brear, Aleksei Lulla, Katarzyna A Ciazynska, Veronica T Chang, Joanne Sharp, Megan Neary, Helen Box, Jo Herriott, Edyta Kijak, Lee Tatham, Eleanor G Bentley, Parul Sharma, Adam Kirby, Ximeng Han, James P Stewart, Andrew Owen, John A G Briggs, Marko Hyvönen, Michael J Skynner, Leo C James
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. Nature communications 14 (1) (2023)
Edyta Niezabitowska, Dominic M Gray, Eduardo Gallardo-Toledo, Andrew Owen, Steve P Rannard, Tom O McDonald
Understanding the Degradation of Core-Shell Nanogels Using Asymmetrical Flow Field Flow Fractionation. Journal of functional biomaterials 14 (7) (2023)
Sam Morris, Mark Long, Alison Savage, Andrew Owen, Steven P Rannard, Helen Cauldbeck
Ex vivo transdermal delivery of 3 H-labelled atovaquone solid drug nanoparticles: a comparison of topical, intradermal injection and microneedle assisted administration. Nanoscale advances 5 (23) (2023)
Frauke Seehusen, Jordan J Clark, Parul Sharma, Eleanor G Bentley, Adam Kirby, Krishanthi Subramaniam, Sabina Wunderlin-Giuliani, Grant L Hughes, Edward I Patterson, Benedict Daniel Michael, Andrew Owen, Julian A Hiscox, James P Stewart, Anja Kipar
Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse. Viruses 14 (5) (2022)
Adeniyi Olagunju, Jacinta Nwamaka Nwogu, Oluwasegun Eniayewu, Shakir Atoyebi, Alieu Amara, John Kpamor, Oluseye Oladotun Bolaji, Ebunoluwa Adejuyigbe, Andrew Owen, Saye H Khoo
Validation and clinical application of a method to quantify efavirenz in cervicovaginal secretions from flocked swabs using liquid chromatography tandem mass spectrometry. Wellcome open research 6 (2022)
Frauke Assmus, Jean-Sélim Driouich, Rana Abdelnabi, Laura Vangeel, Franck Touret, Ayorinde Adehin, Palang Chotsiri, Maxime Cochin, Caroline S Foo, Dirk Jochmans, Seungtaek Kim, Léa Luciani, Grégory Moureau, Soonju Park, Paul-Rémi Pétit, David Shum, Thanaporn Wattanakul, Birgit Weynand, Laurent Fraisse, Jean-Robert Ioset, Charles E Mowbray, Andrew Owen, Richard M Hoglund, Joel Tarning, Xavier de Lamballerie, Antoine Nougairède, Johan Neyts, Peter Sjö, Fanny Escudie, Ivan Scandale, Eric Chatelain
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19. Microorganisms 10 (8) (2022)
Adeniyi Olagunju, Jacinta Nwamaka Nwogu, Oluwasegun Eniayewu, Shakir Atoyebi, Alieu Amara, John Kpamor, Oluseye Oladotun Bolaji, Ebunoluwa Adejuyigbe, Andrew Owen, Saye H Khoo
Validation and clinical application of a method to quantify efavirenz in cervicovaginal secretions from flocked swabs using liquid chromatography tandem mass spectrometry. Wellcome open research 6 (2022)
Carolina de Queiroz Sacramento, Natalia Fintelman-Rodrigues, Suelen Silva Gomes Dias, Jairo Ramos Temerozo, Aline de Paula D Da Silva, Carine S da Silva, Camilla Blanco, André C Ferreira, Mayara Mattos, Vinicius Cardoso Soares, Filipe Santos Pereira-Dutra, Milene Dias Miranda, Debora Ferreira Barreto-Vieira, Marcos Alexandre Nunes da Silva, Suzana S Santos, Mateo Torres, Otávio Augusto Chaves, Rajith Kumar Reddy Rajoli, Alberto Paccanaro, Andrew Owen, Dumith Chequer Bou-Habib, Patrícia Torres Bozza, Thiago Moreno L Souza
Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells. Viruses 14 (2) (2022)
Simiso Mandisa Sokhela, Bronwyn Bosch, Andrew Hill, Bryony Simmons, Joana Woods, Hilary Johnstone, Godspower Akpomiemie, Leah Ellis, Andrew Owen, Carmen Perez Casas, Willem Daniel Francois Venter
Randomized clinical trial of nitazoxanide or sofosbuvir/daclatasvir for the prevention of SARS-CoV-2 infection. The Journal of antimicrobial chemotherapy 77 (10) (2022)
Lee Tatham, Joanne Sharp, Edyta Kijak, Joanne Herriott, Megan Neary, Helen Box, Anthony Valentijn, Helen Cox, Henry Pertinez, Paul Curley, Usman Arshad, Rajith Kr Rajoli, Steve Rannard, James Stewart, Andrew Owen
Lack of Ronapreve (REGN-CoV; casirivimab and imdevimab) virological efficacy against the SARS-CoV-2 Omicron variant (B.1.1.529) in K18-hACE2 mice. bioRxiv : the preprint server for biology (2022)
Teresa Brevini, Mailis Maes, Gwilym J Webb, Binu V John, Claudia D Fuchs, Gustav Buescher, Lu Wang, Chelsea Griffiths, Marnie L Brown, William E Scott, Pehuén Pereyra-Gerber, William T H Gelson, Stephanie Brown, Scott Dillon, Daniele Muraro, Joanne Sharp, Megan Neary, Helen Box, Lee Tatham, James P Stewart, Paul Curley, Henry Pertinez, Sally Forrest, Petra Mlcochova, Sagar S Varankar, Mahnaz Darvish Damavandi, Victoria L Mulcahy, Rhoda E Kuc, Thomas L Williams, James A Heslop, Davide Rossetti, Olivia C Tysoe, Vasileios Galanakis, Marta Vila-Gonzalez, Thomas W M Crozier, Johannes Bargehr, Sanjay Sinha, Sara S Upponi, Corrina Fear, Lisa Swift, Kourosh Saeb Parsy, Susan E Davies, Axel Wester, Hannes Hagström, Espen Melum, Darran Clements, Peter Humphreys, Jo Herriott, Edyta Kijak, Helen Cox, Chloe Bramwell, Anthony Valentijn, Christopher J R Illingworth, null null, Bassam Dahman, Dustin R Bastaich, Raphaella D Ferreira, Thomas Marjot, Eleanor Barnes, Andrew M Moon, Alfred S Barritt, Ravindra Kumar Gupta, Stephen Baker, Anthony P Davenport, Gareth Corbett, Vassilis G Gorgoulis, Simon James Alexander Buczacki, Joo-Hyeon Lee, Nicholas J Matheson, Michael Trauner, Andrew J Fisher, Paul Gibbs, Andrew J Butler, Christopher J E Watson, George F Mells, Gordon Dougan, Andrew Owen, Ansgar W Lohse, Ludovic Vallier, Fotios Sampaziotis
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature (2022)
Rohan Gurjar, Laura Dickinson, Daniel Carr, Wolfgang Stöhr, Stefano Bonora, Andrew Owen, Antonio D'Avolio, Adam Cursley, Nathalie De Castro, Gerd Fätkenheuer, Linos Vandekerckhove, Giovanni Di Perri, Anton Pozniak, Christine Schwimmer, François Raffi, Marta Boffito, null null
Influence of UGT1A1 and SLC22A6 polymorphisms on the population pharmacokinetics and pharmacodynamics of raltegravir in HIV-infected adults: a NEAT001/ANRS143 sub-study. The pharmacogenomics journal (2022)
Carolina Q Sacramento, Natalia Fintelman-Rodrigues, Jairo R Temerozo, Aline de Paula Dias Da Silva, Suelen da Silva Gomes Dias, Carine Dos Santos da Silva, André C Ferreira, Mayara Mattos, Camila R R Pão, Caroline S de Freitas, Vinicius Cardoso Soares, Lucas Villas Bôas Hoelz, Tácio Vinício Amorim Fernandes, Frederico Silva Castelo Branco, Mônica Macedo Bastos, Núbia Boechat, Felipe B Saraiva, Marcelo Alves Ferreira, Steffen Jockusch, Xuanting Wang, Chuanjuan Tao, Minchen Chien, Wei Xie, Dinshaw Patel, Aitor Garzia, Thomas Tuschl, James J Russo, Rajith K R Rajoli, Carolina S G Pedrosa, Gabriela Vitória, Letícia R Q Souza, Livia Goto-Silva, Marilia Zaluar Guimarães, Stevens K Rehen, Andrew Owen, Fernando A Bozza, Dumith Chequer Bou-Habib, Jingyue Ju, Patrícia T Bozza, Thiago Moreno L Souza
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19. The Journal of antimicrobial chemotherapy 76 (7) (2021)
Lauren E Walker, Richard FitzGerald, Geoffrey Saunders, Rebecca Lyon, Michael Fisher, Karen Martin, Izabela Eberhart, Christie Woods, Sean Ewings, Colin Hale, Rajith K R Rajoli, Laura Else, Sujan Dilly-Penchala, Alieu Amara, David G Lalloo, Michael Jacobs, Henry Pertinez, Parys Hatchard, Robert Waugh, Megan Lawrence, Lucy Johnson, Keira Fines, Helen Reynolds, Timothy Rowland, Rebecca Crook, Emmanuel Okenyi, Kelly Byrne, Pavel Mozgunov, Thomas Jaki, Saye H Khoo, Andrew Owen, Gareth Griffiths, Thomas E Fletcher, null null
An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2. Clinical pharmacology and therapeutics (2021)
Ethel D Weld, Jacqueline Astemborski, Gregory D Kirk, Mark S Sulkowski, Katz Stephanie, Richard Rothman, Sunil S Solomon, Gail V Matthews, Yu-Hsiang Hsieh, Malvika Verma, Giovanni Traverso, Susan Swindells, Andrew Owen, Jordan Feld, Charles Flexner, Shruti H Mehta, David L Thomas
Preferences of Persons with or at Risk for Hepatitis C for Long-Acting Treatments. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Henry Pertinez, Rajith Kr Rajoli, Saye H Khoo, Andrew Owen
Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2. medRxiv : the preprint server for health sciences (2021)
Ralf Salzer, Jordan J Clark, Marina Vaysburd, Veronica T Chang, Anna Albecka, Leo Kiss, Parul Sharma, Andres Gonzalez Llamazares, Anja Kipar, Julian A Hiscox, Andrew Owen, A Radu Aricescu, James P Stewart, Leo C James, Jan Löwe
Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice. FEBS letters 595 (18) (2021)
M Neary, H Box, J Sharp, L Tatham, P Curley, J Herriott, E Kijak, U Arshad, J J Hobson, Rkr Rajoli, H Pertinez, A Valentijn, K Dhaliwal, F McCaughan, S P Rannard, A Kipar, J P Stewart, Andrew Owen
Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters. bioRxiv : the preprint server for biology (2021)
Julian A Hiscox, Saye H Khoo, James P Stewart, Andrew Owen
Shutting the gate before the horse has bolted: is it time for a conversation about SARS-CoV-2 and antiviral drug resistance? The Journal of antimicrobial chemotherapy 76 (9) (2021)
Adeniyi Olagunju, Jacinta Nwamaka Nwogu, Oluwasegun Eniayewu, Shakir Atoyebi, Alieu Amara, John Kpamor, Oluseye Oladotun Bolaji, Ebunoluwa Adejuyigbe, Andrew Owen, Saye H Khoo
Validation and clinical application of a method to quantify efavirenz in cervicovaginal secretions from flocked swabs using liquid chromatography tandem mass spectrometry. Wellcome open research 6 (2021)
Henry Pertinez, Rajith Kumar Reddy Rajoli, Saye H Khoo, Andrew Owen
Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5'-triphosphate exposure to support posology for SARS-CoV-2. The Journal of antimicrobial chemotherapy 76 (8) (2021)
Jiandong Huo, Halina Mikolajek, Audrey Le Bas, Jordan J Clark, Parul Sharma, Anja Kipar, Joshua Dormon, Chelsea Norman, Miriam Weckener, Daniel K Clare, Peter J Harrison, Julia A Tree, Karen R Buttigieg, Francisco J Salguero, Robert J Watson, Daniel Knott, Oliver T Carnell, Didier Ngabo, Michael J Elmore, Susan Fotheringham, Adam Harding, Lucile Moynié, Philip N Ward, Maud Dumoux, Tessa Prince, Yper Hall, Julian A Hiscox, Andrew Owen, William S James, Miles W Carroll, James P Stewart, James H Naismith, Raymond J Owens
A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19. Nature communications 12 (1) (2021)
Usman Arshad, Henry Pertinez, Helen Box, Lee Tatham, Rajith K R Rajoli, Paul Curley, Megan Neary, Joanne Sharp, Neill J Liptrott, Anthony Valentijn, Christopher A W David, Steven P Rannard, Paul M O'Neill, Ghaith Aljayyoussi, Shaun H Pennington, Stephen A Ward, Andrew Hill, David J Back, Saye H Khoo, Patrick G Bray, Giancarlo A Biagini, Andrew Owen
Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics. Clinical pharmacology and therapeutics 108 (4) (2020)
Christopher A W David, Michael Barrow, Patricia Murray, Matthew J Rosseinsky, Andrew Owen, Neill J Liptrott
In Vitro Determination of the Immunogenic Impact of Nanomaterials on Primary Peripheral Blood Mononuclear Cells. International journal of molecular sciences 21 (16) (2020)
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Lee M Tatham, Neill J Liptrott, Steven P Rannard, Andrew Owen
Long-Acting Injectable Statins-Is It Time for a Paradigm Shift? Molecules (Basel, Switzerland) 24 (15) (2019)
James J Hobson, Amer Al-Khouja, Paul Curley, David Meyers, Charles Flexner, Marco Siccardi, Andrew Owen, Caren Freel Meyers, Steven P Rannard
Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies. Nature communications 10 (1) (2019)
Rahul P Bakshi, Lee M Tatham, Alison C Savage, Abhai K Tripathi, Godfree Mlambo, Matthew M Ippolito, Elizabeth Nenortas, Steve P Rannard, Andrew Owen, Theresa A Shapiro
Long-acting injectable atovaquone nanomedicines for malaria prophylaxis. Nature communications 9 (1) (2018)