Aneel K Aggarwal (Aneel Aggarwal)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 33

Top Topics

High Resolution

Cancer Stem Cells

Saccharomyces Cerevisiae

Top Venues

Nature structural & molecular biology

Nature communications

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

Jithesh Kottur, Radhika Malik, Aneel K Aggarwal
Nucleic acid mediated activation of a short prokaryotic Argonaute immune system. Nature communications 15 (1) (2024)
Radhika Malik, Robert E Johnson, Iban Ubarretxena-Belandia, Louise Prakash, Satya Prakash, Aneel K Aggarwal
Cryo-EM structure of the Rev1-Polζ holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis. Nature structural & molecular biology (2024)
Olga Rechkoblit, Daniela Sciaky, Dale F Kreitler, Angeliki Buku, Jithesh Kottur, Aneel K Aggarwal
Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nature structural & molecular biology (2024)
Olga Rechkoblit, Daniela Sciaky, Dale F Kreitler, Angeliki Buku, Jithesh Kottur, Aneel K Aggarwal
Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nature structural & molecular biology 31 (5) (2024)
Duc-Duy Vu, Alessio Bonucci, Manon Brenière, Metztli Cisneros-Aguirre, Philippe Pelupessy, Ziqing Wang, Ludovic Carlier, Guillaume Bouvignies, Patricia Cortes, Aneel K Aggarwal, Martin Blackledge, Zoher Gueroui, Valérie Belle, Jeremy M Stark, Mauro Modesti, Fabien Ferrage
Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro. Nature structural & molecular biology (2024)
Jithesh Kottur, Radhika Malik, Aneel K Aggarwal
Nucleic acid mediated activation of a short prokaryotic Argonaute immune system. Nature communications 15 (1) (2024)
Jithesh Kottur, Radhika Malik, Aneel K Aggarwal
Nucleic acid mediated activation of a short prokaryotic Argonaute immune system. Nature communications 15 (1) (2024)
Richard Quintana-Feliciano, Jithesh Kottur, Mi Ni, Rikhia Ghosh, Leslie Salas-Estrada, Goran Ahlsen, Olga Rechkoblit, Lawrence Shapiro, Marta Filizola, Gang Fang, Aneel K Aggarwal
Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation. Nature communications 15 (1) (2024)
Olga Rechkoblit, Daniela Sciaky, Dale F Kreitler, Angeliki Buku, Jithesh Kottur, Aneel K Aggarwal
Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nature structural & molecular biology 31 (5) (2024)
Duc-Duy Vu, Alessio Bonucci, Manon Brenière, Metztli Cisneros-Aguirre, Philippe Pelupessy, Ziqing Wang, Ludovic Carlier, Guillaume Bouvignies, Patricia Cortes, Aneel K Aggarwal, Martin Blackledge, Zoher Gueroui, Valérie Belle, Jeremy M Stark, Mauro Modesti, Fabien Ferrage
Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro. Nature structural & molecular biology (2024)
Olga Rechkoblit, Daniela Sciaky, Dale F Kreitler, Angeliki Buku, Jithesh Kottur, Aneel K Aggarwal
Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nature structural & molecular biology 31 (5) (2024)
Jithesh Kottur, Radhika Malik, Aneel K Aggarwal
Nucleic acid mediated activation of a short prokaryotic Argonaute immune system. Nature communications 15 (1) (2024)
Jithesh Kottur, Radhika Malik, Aneel K Aggarwal
Nucleic acid mediated activation of a short prokaryotic Argonaute immune system. Nature communications 15 (1) (2024)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Aneel K Aggarwal, Jithesh Kottur, Radhika Malik
Nucleic Acid Mediated Activation of a Short Prokaryotic Argonaute Immune System. bioRxiv : the preprint server for biology (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Jithesh Kottur, Kris M White, M Luis Rodriguez, Olga Rechkoblit, Richard Quintana-Feliciano, Ahana Nayar, Adolfo García-Sastre, Aneel K Aggarwal
Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. PLoS pathogens 19 (7) (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology (2023)
Yuliang Tan, Lu Yao, Amir Gamliel, Sreejith J Nair, Havilah Taylor, Kenny Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes. Nature structural & molecular biology 30 (2) (2023)
Jithesh Kottur, Olga Rechkoblit, Richard Quintana-Feliciano, Daniela Sciaky, Aneel K Aggarwal
High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development. Nature structural & molecular biology 29 (9) (2022)
Aneel K Aggarwal, Jithesh Kottur
High resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development. Research square (2022)
Radhika Malik, Robert E Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K Aggarwal
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch. Nature communications 13 (1) (2022)
Olga Rechkoblit, Robert E Johnson, Yogesh K Gupta, Louise Prakash, Satya Prakash, Aneel K Aggarwal
Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase. Nature communications 12 (1) (2021)
Xufen Yu, Dongxu Li, Jithesh Kottur, Yudao Shen, Huen Suk Kim, Kwang-Su Park, Yi-Hsuan Tsai, Weida Gong, Jun Wang, Kyogo Suzuki, Joel S Parker, Laura E Herring, Husnu Ümit Kaniskan, Ling Cai, Rinku Jain, Jing Liu, Aneel K Aggarwal, Gang Greg Wang, Jian Jin
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Science translational medicine 13 (613) (2021)
Fan Yang, Bogdan Tanasa, Rudi Micheletti, Kenneth A Ohgi, Aneel K Aggarwal, Michael G Rosenfeld
Shape of promoter antisense RNAs regulates ligand-induced transcription activation. Nature 595 (7867) (2021)
Katsutoshi Sato, Amol A Padgaonkar, Stacey J Baker, Stephen C Cosenza, Olga Rechkoblit, D R C Venkata Subbaiah, Josep Domingo-Domenech, Alison Bartkowski, Elisa R Port, Aneel K Aggarwal, M V Ramana Reddy, Hanna Y Irie, E Premkumar Reddy
Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease. Nature communications 12 (1) (2021)
Radhika Malik, Mykhailo Kopylov, Yacob Gomez-Llorente, Rinku Jain, Robert E Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K Aggarwal
Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis. Nature structural & molecular biology 27 (10) (2020)
Rinku Jain, William J Rice, Radhika Malik, Robert E Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K Aggarwal
Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme. Nature structural & molecular biology 26 (10) (2019)