Jonathan F Fay (Jonathan Fay)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Topics

Pain Management

Atopic Dermatitis

Top Venues

Nature communications

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

Daphne Chun-Che Chien, Nathachit Limjunyawong, Can Cao, James Meixiong, Qi Peng, Cheng-Ying Ho, Jonathan F Fay, Bryan L Roth, Xinzhong Dong
MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Science translational medicine 16 (746) (2024)
Kevin M Knight, Brian E Krumm, Nicholas J Kapolka, W Grant Ludlam, Meng Cui, Sepehr Mani, Iya Prytkova, Elizabeth G Obarow, Tyler J Lefevre, Wenyuan Wei, Ning Ma, Xi Ping Huang, Jonathan F Fay, Nagarajan Vaidehi, Alan V Smrcka, Paul A Slesinger, Diomedes E Logothetis, Kirill A Martemyanov, Bryan L Roth, Henrik G Dohlman
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state. Nature communications 15 (1) (2024)
Kevin M Knight, Brian E Krumm, Nicholas J Kapolka, W Grant Ludlam, Meng Cui, Sepehr Mani, Iya Prytkova, Elizabeth G Obarow, Tyler J Lefevre, Wenyuan Wei, Ning Ma, Xi Ping Huang, Jonathan F Fay, Nagarajan Vaidehi, Alan V Smrcka, Paul A Slesinger, Diomedes E Logothetis, Kirill A Martemyanov, Bryan L Roth, Henrik G Dohlman
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state. Nature communications 15 (1) (2024)
Daphne Chun-Che Chien, Nathachit Limjunyawong, Can Cao, James Meixiong, Qi Peng, Cheng-Ying Ho, Jonathan F Fay, Bryan L Roth, Xinzhong Dong
MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Science translational medicine 16 (746) (2024)
Tao Che, Balazs Varga, Sarah M Bernhard, Amal El Daibani, Saheem Zaidi, Jordy Homing Lam, Jhoan Aguilar, Kevin Appourchaux, Antonina Nazarova, Alexa Kouvelis, Shainnel Eans, Elyssa B Margolis, Jonathan F Fay, Amynah Amir Ali Pradhan, Vsevolod Katritch, Jay P McLaughlin, Susruta Majumdar
Structure-Guided Design of Partial Agonists at an Opioid Receptor. Research square (2024)
Tao Che, Balazs Varga, Sarah M Bernhard, Amal El Daibani, Saheem Zaidi, Jordy Homing Lam, Jhoan Aguilar, Kevin Appourchaux, Antonina Nazarova, Alexa Kouvelis, Shainnel Eans, Elyssa B Margolis, Jonathan F Fay, Amynah Amir Ali Pradhan, Vsevolod Katritch, Jay P McLaughlin, Susruta Majumdar
Structure-Guided Design of Partial Agonists at an Opioid Receptor. Research square (2024)
Tao Che, Balazs Varga, Sarah M Bernhard, Amal El Daibani, Saheem Zaidi, Jordy Homing Lam, Jhoan Aguilar, Kevin Appourchaux, Antonina Nazarova, Alexa Kouvelis, Shainnel Eans, Elyssa B Margolis, Jonathan F Fay, Amynah Amir Ali Pradhan, Vsevolod Katritch, Jay P McLaughlin, Susruta Majumdar
Structure-Guided Design of Partial Agonists at an Opioid Receptor. Research square (2024)
Daphne Chun-Che Chien, Nathachit Limjunyawong, Can Cao, James Meixiong, Qi Peng, Cheng-Ying Ho, Jonathan F Fay, Bryan L Roth, Xinzhong Dong
MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Science translational medicine 16 (746) (2024)
Kevin M Knight, Brian E Krumm, Nicholas J Kapolka, W Grant Ludlam, Meng Cui, Sepehr Mani, Iya Prytkova, Elizabeth G Obarow, Tyler J Lefevre, Wenyuan Wei, Ning Ma, Xi Ping Huang, Jonathan F Fay, Nagarajan Vaidehi, Alan V Smrcka, Paul A Slesinger, Diomedes E Logothetis, Kirill A Martemyanov, Bryan L Roth, Henrik G Dohlman
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state. Nature communications 15 (1) (2024)
Edin Muratspahić, Kristine Deibler, Jianming Han, Nataša Tomašević, Kirtikumar B Jadhav, Aina-Leonor Olivé-Marti, Nadine Hochrainer, Roland Hellinger, Johannes Koehbach, Jonathan F Fay, Mohammad Homaidur Rahman, Lamees Hegazy, Timothy W Craven, Balazs R Varga, Gaurav Bhardwaj, Kevin Appourchaux, Susruta Majumdar, Markus Muttenthaler, Parisa Hosseinzadeh, David J Craik, Mariana Spetea, Tao Che, Julien S Baker, Christian W Gruber
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nature communications 14 (1) (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature 617 (7960) (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature 617 (7960) (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature 617 (7960) (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature 617 (7960) (2023)
Brian E Krumm, Jeffrey F DiBerto, Reid H J Olsen, Hye Jin Kang, Samuel T Slocum, Shicheng Zhang, Ryan T Strachan, Xi-Ping Huang, Lauren M Slosky, Anthony B Pinkerton, Lawrence S Barak, Marc G Caron, Terry Kenakin, Jonathan F Fay, Bryan L Roth
Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature 617 (7960) (2023)
Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Ligand and G-protein selectivity in the κ-opioid receptor. Nature 617 (7960) (2023)
Luba A Aleksandrov, Adrei A Aleksandrov, Timothy J Jensen, Joshua D Strauss, Jonathan F Fay
Conformational Variability in Ground-State CFTR Lipoprotein Particle Cryo-EM Ensembles. International journal of molecular sciences 23 (16) (2022)
Shicheng Zhang, He Chen, Chengwei Zhang, Ying Yang, Petr Popov, Jing Liu, Brian E Krumm, Can Cao, Kuglae Kim, Yan Xiong, Vsevolod Katritch, Brian K Shoichet, Jian Jin, Jonathan F Fay, Bryan L Roth
Inactive and active state structures template selective tools for the human 5-HT 5A receptor. Nature structural & molecular biology 29 (7) (2022)
Yong-Feng Liu, Can Cao, Xi-Ping Huang, Ryan H Gumpper, Moira M Rachman, Sheng-Luen Shih, Brian E Krumm, Shicheng Zhang, Brian K Shoichet, Jonathan F Fay, Bryan L Roth
Ligand recognition and allosteric modulation of the human MRGPRX1 receptor. Nature chemical biology (2022)
Shicheng Zhang, Ryan H Gumpper, Xi-Ping Huang, Yong-Feng Liu, Brian E Krumm, Can Cao, Jonathan F Fay, Bryan L Roth
Molecular basis for selective activation of DREADD-based chemogenetics. Nature 612 (7939) (2022)
Jared V Peck, Jonathan F Fay, Joshua D Strauss
High-speed high-resolution data collection on a 200 keV cryo-TEM. IUCrJ 9 (Pt 2) (2022)
Can Cao, Hye Jin Kang, Isha Singh, He Chen, Chengwei Zhang, Wenlei Ye, Byron W Hayes, Jing Liu, Ryan H Gumpper, Brian J Bender, Samuel T Slocum, Brian E Krumm, Katherine Lansu, John D McCorvy, Wesley K Kroeze, Justin G English, Jeffrey F DiBerto, Reid H J Olsen, Xi-Ping Huang, Shicheng Zhang, Yong-Feng Liu, Kuglae Kim, Joel Karpiak, Lily Yeh Jan, Soman N Abraham, Jian Jin, Brian K Shoichet, Jonathan F Fay, Bryan L Roth
Structure, function and pharmacology of human itch GPCRs. Nature 600 (7887) (2021)
Jonathan F Fay, Luba A Aleksandrov, Timothy J Jensen, Liying L Cui, Joseph N Kousouros, Lihua He, Andrei A Aleksandrov, Drew S Gingerich, John R Riordan, James Z Chen
Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel. Biochemistry 57 (43) (2018)
Luba A Aleksandrov, Jonathan F Fay, John R Riordan
R-Domain Phosphorylation by Protein Kinase A Stimulates Dissociation of Unhydrolyzed ATP from the First Nucleotide-Binding Site of the Cystic Fibrosis Transmembrane Conductance Regulator. Biochemistry 57 (34) (2018)