Evan Z Macosko (Evan Macosko)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 45

Top Venues

Nature

bioRxiv : the preprint server for biology

Nature communications

Nature neuroscience

Massachusetts General Hospital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital Nov 01 2016

United States

Assistant Professor :: Psychiatry

Publications

Gordon Fishell, Sherry Wu, Min Dai, Shang-Po Yang, Cai McCann, Yanjie Qiu, Giovanni Marrero, Jeffrey Stogsdill, Daniela Di Bella, Qing Xu, Samouil L Farhi, Evan Z Macosko, Fei Chen
Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes. Research square (2024)
Chenlei Hu, Mehdi Borji, Giovanni J Marrero, Vipin Kumar, Jackson A Weir, Sachin V Kammula, Evan Z Macosko, Fei Chen
Scalable imaging-free spatial genomics through computational reconstruction. bioRxiv : the preprint server for biology (2024)
Sung Jin Park, I-Hao Wang, Namgyu Lee, Hao-Ching Jiang, Takeshi Uemura, Kensuke Futai, Dohoon Kim, Evan Z Macosko, Paul Greer
Combinatorial expression of neurexin genes regulates glomerular targeting by olfactory sensory neurons. bioRxiv : the preprint server for biology (2024)
Sherry Jingjing Wu, Min Dai, Shang-Po Yang, Cai McCann, Yanjie Qiu, Giovanni J Marrero, Jeffrey A Stogsdill, Daniela J Di Bella, Qing Xu, Samouil L Farhi, Evan Z Macosko, Fei Chen, Gordon Fishell
Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes. bioRxiv : the preprint server for biology (2024)
Chenlei Hu, Mehdi Borji, Giovanni J Marrero, Vipin Kumar, Jackson A Weir, Sachin V Kammula, Evan Z Macosko, Fei Chen
Scalable imaging-free spatial genomics through computational reconstruction. bioRxiv : the preprint server for biology (2024)
Gordon Fishell, Sherry Wu, Min Dai, Shang-Po Yang, Cai McCann, Yanjie Qiu, Giovanni Marrero, Jeffrey Stogsdill, Daniela Di Bella, Qing Xu, Samouil L Farhi, Evan Z Macosko, Fei Chen
Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes. Research square (2024)
Chenlei Hu, Mehdi Borji, Giovanni J Marrero, Vipin Kumar, Jackson A Weir, Sachin V Kammula, Evan Z Macosko, Fei Chen
Scalable imaging-free spatial genomics through computational reconstruction. bioRxiv : the preprint server for biology (2024)
Sherry Jingjing Wu, Min Dai, Shang-Po Yang, Cai McCann, Yanjie Qiu, Giovanni J Marrero, Jeffrey A Stogsdill, Daniela J Di Bella, Qing Xu, Samouil L Farhi, Evan Z Macosko, Fei Chen, Gordon Fishell
Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes. bioRxiv : the preprint server for biology (2024)
Sherry Jingjing Wu, Min Dai, Shang-Po Yang, Cai McCann, Yanjie Qiu, Giovanni J Marrero, Jeffrey A Stogsdill, Daniela Di Bella, Qing Xu, Samouil L Farhi, Evan Z Macosko, Fei Chen, Gordon Fishell
Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes. Research square (2024)
Andrew J C Russell, Jackson A Weir, Naeem M Nadaf, Matthew Shabet, Vipin Kumar, Sandeep Kambhampati, Ruth Raichur, Giovanni J Marrero, Sophia Liu, Karol S Balderrama, Charles R Vanderburg, Vignesh Shanmugam, Lu-Yi Tian, J Bryan Iorgulescu, Charles H Yoon, Catherine J Wu, Evan Z Macosko, Fei Chen
Publisher Correction: Slide-tags enables single-nucleus barcoding for multimodal spatial genomics. Nature (2023)
Elizabeth P Lackey, Luis Moreira, Aliya Norton, Marie E Hemelt, Tomas Osorno, Tri M Nguyen, Evan Z Macosko, Wei-Chung Allen Lee, Court A Hull, Wade G Regehr
Cerebellar circuits for disinhibition and synchronous inhibition. bioRxiv : the preprint server for biology (2023)
Jonah Langlieb, Nina S Sachdev, Karol S Balderrama, Naeem M Nadaf, Mukund Raj, Evan Murray, James T Webber, Charles R Vanderburg, Vahid Gazestani, Daniel Tward, Chris Mezias, Xu Li, Katelyn Flowers, Dylan M Cable, Tabitha Norton, Partha P Mitra, Fei Chen, Evan Z Macosko
The molecular cytoarchitecture of the adult mouse brain. Nature 624 (7991) (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Andrew J C Russell, Jackson A Weir, Naeem M Nadaf, Matthew Shabet, Vipin Kumar, Sandeep Kambhampati, Ruth Raichur, Giovanni J Marrero, Sophia Liu, Karol S Balderrama, Charles R Vanderburg, Vignesh Shanmugam, Lu-Yi Tian, J Bryan Iorgulescu, Charles H Yoon, Catherine J Wu, Evan Z Macosko, Fei Chen
Slide-tags enables single-nucleus barcoding for multimodal spatial genomics. Nature (2023)
Daniel R Hochbaum, Alexandra C Dubinsky, Hannah C Farnsworth, Lauren Hulshof, Giona Kleinberg, Amanda Urke, Wengang Wang, Richard Hakim, Keira Robertson, Canaria Park, Alyssa Solberg, Yechan Yang, Caroline Baynard, Naeem M Nadaf, Celia C Beron, Allison E Girasole, Lynne Chantranupong, Marissa Cortopassi, Shannon Prouty, Ludwig Geistlinger, Alexander Banks, Thomas Scanlan, Michael E Greenberg, Gabriella L Boulting, Evan Z Macosko, Bernardo L Sabatini
Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive. bioRxiv : the preprint server for biology (2023)
Tushar Kamath, Evan Z Macosko
Insights into Neurodegeneration in Parkinson's Disease from Single-Cell and Spatial Genomics. Movement disorders : official journal of the Movement Disorder Society (2023)
Blue B Lake, Rajasree Menon, Seth Winfree, Qiwen Hu, Ricardo Melo Ferreira, Kian Kalhor, Daria Barwinska, Edgar A Otto, Michael Ferkowicz, Dinh Diep, Nongluk Plongthongkum, Amanda Knoten, Sarah Urata, Laura H Mariani, Abhijit S Naik, Sean Eddy, Bo Zhang, Yan Wu, Diane Salamon, James C Williams, Xin Wang, Karol S Balderrama, Paul J Hoover, Evan Murray, Jamie L Marshall, Teia Noel, Anitha Vijayan, Austin Hartman, Fei Chen, Sushrut S Waikar, Sylvia E Rosas, Francis Perry Wilson, Susan T Crowley, Krzysztof Kiryluk, John R Sedor, Robert D Toto, Chirag R Parikh, Eric H Kim, Rahul Satija, Anna Greka, Evan Z Macosko, Peter V Kharchenko, Joseph P Gaut, Jeffrey B Hodgin, null null, Michael T Eadon, Pierre C Dagher, Tarek M El-Achkar, Kun Zhang, Matthias Kretzler, Sanjay Jain
An atlas of healthy and injured cell states and niches in the human kidney. Nature 619 (7970) (2023)
Christopher H Chen, Leannah N Newman, Amanda P Stark, Katherine E Bond, Dawei Zhang, Stefano Nardone, Charles R Vanderburg, Naeem M Nadaf, Zhiyi Yao, Kefiloe Mutume, Isabella Flaquer, Bradford B Lowell, Evan Z Macosko, Wade G Regehr
A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain. Nature neuroscience 26 (11) (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Jonah Langlieb, Nina S Sachdev, Karol S Balderrama, Naeem M Nadaf, Mukund Raj, Evan Murray, James T Webber, Charles R Vanderburg, Vahid Gazestani, Daniel J Tward, Chris Mezias, Xu Li, Dylan Cable, Tabitha Norton, Partha Pratim Mitra, Fei Chen, Evan Z Macosko
The cell type composition of the adult mouse brain revealed by single cell and spatial genomics. bioRxiv : the preprint server for biology (2023)
Tushar Kamath, Evan Z Macosko
Insights into Neurodegeneration in Parkinson's Disease from Single-Cell and Spatial Genomics. Movement disorders : official journal of the Movement Disorder Society (2023)
Michael-John Dolan, Martine Therrien, Saša Jereb, Tushar Kamath, Vahid Gazestani, Trevor Atkeson, Samuel E Marsh, Aleksandrina Goeva, Neal M Lojek, Sarah Murphy, Cassandra M White, Julia Joung, Bingxu Liu, Francesco Limone, Kevin Eggan, Nir Hacohen, Bradley E Bernstein, Christopher K Glass, Ville Leinonen, Mathew Blurton Jones, Feng Zhang, Charles B Epstein, Evan Z Macosko, Beth Stevens
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nature immunology (2023)
Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z Macosko, Léo Guignard, Fei Chen, Alexander Meissner
Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nature genetics (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Andrew J C Russell, Jackson A Weir, Naeem M Nadaf, Matthew Shabet, Vipin Kumar, Sandeep Kambhampati, Ruth Raichur, Giovanni J Marrero, Sophia Liu, Karol S Balderrama, Charles R Vanderburg, Vignesh Shanmugam, Lu-Yi Tian, J Bryan Iorgulescu, Charles H Yoon, Catherine J Wu, Evan Z Macosko, Fei Chen
Publisher Correction: Slide-tags enables single-nucleus barcoding for multimodal spatial genomics. Nature (2023)
Taghreed Hirz, Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte M Verhoeven, Alexander O Subtelny, Dimitar V Zlatev, Matthew W Wszolek, Keyan Salari, Evan Murray, Fei Chen, Evan Z Macosko, Chin-Lee Wu, David T Scadden, Douglas M Dahl, Ninib Baryawno, Philip J Saylor, Peter V Kharchenko, David Brian Sykes
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses. Nature communications 14 (1) (2023)
Vahid Gazestani, Tushar Kamath, Naeem M Nadaf, S J Burris, Brendan Rooney, Antti Junkkari, Charles Vanderburg, Tuomas Rauramaa, Martine Therrien, Matthew Tegtmeyer, Sanna-Kaisa Herukka, Abdulraouf Abdulraouf, Samuel Marsh, Tarja Malm, Mikko Hiltunen, Ralda Nehme, Beth Stevens, Ville Leinonen, Evan Z Macosko
Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. bioRxiv : the preprint server for biology (2023)
Luyi Tian, Fei Chen, Evan Z Macosko
The expanding vistas of spatial transcriptomics. Nature biotechnology (2022)
Dylan M Cable, Evan Murray, Vignesh Shanmugam, Simon Zhang, Luli S Zou, Michael Diao, Haiqi Chen, Evan Z Macosko, Rafael A Irizarry, Fei Chen
Cell type-specific inference of differential expression in spatial transcriptomics. Nature methods 19 (9) (2022)
Samuel E Marsh, Alec J Walker, Tushar Kamath, Lasse Dissing-Olesen, Timothy R Hammond, T Yvanka de Soysa, Adam M H Young, Sarah Murphy, Abdulraouf Abdulraouf, Naeem M Nadaf, Connor Dufort, Alicia C Walker, Liliana E Lucca, Velina Kozareva, Charles R Vanderburg, Soyon Hong, Harry Bulstrode, Peter J Hutchinson, Daniel J Gaffney, David A Hafler, Robin J M Franklin, Evan Z Macosko, Beth Stevens
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain. Nature neuroscience 25 (3) (2022)
Tomás Osorno, Stephanie Rudolph, Tri M Nguyen, Velina Kozareva, Naeem M Nadaf, Aliya Norton, Evan Z Macosko, Wei-Chung Allen Lee, Wade G Regehr
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties. Nature neuroscience 25 (6) (2022)
I-Hao Wang, Evan Murray, Greg Andrews, Hao-Ching Jiang, Sung Jin Park, Elisa Donnard, Violeta Durán-Laforet, Daniel M Bear, Travis E Faust, Manuel Garber, Christina E Baer, Dorothy P Schafer, Nishigandha Phalke, Fei Chen, Evan Z Macosko, Paul L Greer
Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. Nature neuroscience 25 (4) (2022)
Tushar Kamath, Abdulraouf Abdulraouf, S J Burris, Jonah Langlieb, Vahid Gazestani, Naeem M Nadaf, Karol S Balderrama, Charles R Vanderburg, Evan Z Macosko
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson's disease. Nature neuroscience 25 (5) (2022)
Jialiang S Wang, Tushar Kamath, Courtney M Mazur, Fatemeh Mirzamohammadi, Daniel Rotter, Hironori Hojo, Christian D Castro, Nicha Tokavanich, Rushi Patel, Nicolas Govea, Tetsuya Enishi, Yunshu Wu, Janaina Da Silva Martins, Michael Bruce, Daniel J Brooks, Mary L Bouxsein, Danielle Tokarz, Charles P Lin, Abdul Abdul, Evan Z Macosko, Melissa Fiscaletti, Craig F Munns, Pearl Ryder, Maria Kost-Alimova, Patrick Byrne, Beth A Cimini, Makoto Fujiwara, Henry M Kronenberg, Marc N Wein
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin. Nature communications 12 (1) (2021)
Dylan M Cable, Evan Murray, Luli S Zou, Aleksandrina Goeva, Evan Z Macosko, Fei Chen, Rafael A Irizarry
Robust decomposition of cell type mixtures in spatial transcriptomics. Nature biotechnology (2021)
Tongtong Zhao, Zachary D Chiang, Julia W Morriss, Lindsay M LaFave, Evan M Murray, Isabella Del Priore, Kevin Meli, Caleb A Lareau, Naeem M Nadaf, Jilong Li, Andrew Scott Earl, Evan Z Macosko, Tyler Jacks, Jason D Buenrostro, Fei Chen
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues. Nature 601 (7891) (2021)
Chong Guo, Vincent Huson, Evan Z Macosko, Wade G Regehr
Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells. Nature communications 12 (1) (2021)
Trygve E Bakken, Nikolas L Jorstad, Qiwen Hu, Blue B Lake, Wei Tian, Brian E Kalmbach, Megan Crow, Rebecca D Hodge, Fenna M Krienen, Staci A Sorensen, Jeroen Eggermont, Zizhen Yao, Brian D Aevermann, Andrew I Aldridge, Anna Bartlett, Darren Bertagnolli, Tamara Casper, Rosa G Castanon, Kirsten Crichton, Tanya L Daigle, Rachel Dalley, Nick Dee, Nikolai C Dembrow, Dinh Diep, Song-Lin Ding, Weixiu Dong, Rongxin Fang, Stephan Fischer, Melissa Goldman, Jeff Goldy, Lucas T Gray, Brian R Herb, Xiaomeng Hou, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Baldur van Lew, Yang Eric Li, Christine S Liu, Hanqing Liu, Jacinta D Lucero, Anup A Mahurkar, Delissa McMillen, Jeremy A Miller, Marmar Moussa, Joseph R Nery, Philip R Nicovich, Sheng-Yong Niu, Joshua Orvis, Julia K Osteen, Scott Owen, Carter R Palmer, Trangthanh H Pham, Nongluk Plongthongkum, Olivier Poirion, Nora M Reed, Christine Rimorin, Angeline Rivkin, William J Romanow, Adriana E Sedeño-Cortés, Kimberly Siletti, Saroja Somasundaram, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Xinxin Wang, Fangming Xie, Anna Marie Yanny, Renee Zhang, Seth A Ament, M Margarita Behrens, Hector Corrada Bravo, Jerold Chun, Alexander Dobin, Jesse Gillis, Ronna Hertzano, Patrick R Hof, Thomas Höllt, Gregory D Horwitz, C Dirk Keene, Peter V Kharchenko, Andrew L Ko, Boudewijn P F Lelieveldt, Chongyuan Luo, Eran A Mukamel, António Pinto-Duarte, Sebastian Preissl, Aviv Regev, Bing Ren, Richard H Scheuermann, Kimberly A Smith, William J Spain, Owen R White, Christof Koch, Michael J Hawrylycz, Bosiljka Tasic, Evan Z Macosko, Steven A McCarroll, Jonathan T Ting, Hongkui Zeng, Kun Zhang, Guoping Feng, Joseph R Ecker, Sten Linnarsson, Ed S Lein
Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature 598 (7879) (2021)
Tommaso Biancalani, Gabriele Scalia, Lorenzo Buffoni, Raghav Avasthi, Ziqing Lu, Aman Sanger, Neriman Tokcan, Charles R Vanderburg, Åsa Segerstolpe, Meng Zhang, Inbal Avraham-Davidi, Sanja Vickovic, Mor Nitzan, Sai Ma, Ayshwarya Subramanian, Michal Lipinski, Jason Buenrostro, Nik Bear Brown, Duccio Fanelli, Xiaowei Zhuang, Evan Z Macosko, Aviv Regev
Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram. Nature methods 18 (11) (2021)
Velina Kozareva, Caroline Martin, Tomas Osorno, Stephanie Rudolph, Chong Guo, Charles Vanderburg, Naeem Nadaf, Aviv Regev, Wade G Regehr, Evan Z Macosko
A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types. Nature 598 (7879) (2021)
Zizhen Yao, Hanqing Liu, Fangming Xie, Stephan Fischer, Ricky S Adkins, Andrew I Aldridge, Seth A Ament, Anna Bartlett, M Margarita Behrens, Koen Van den Berge, Darren Bertagnolli, Hector Roux de Bezieux, Tommaso Biancalani, Ali Sina Booeshaghi, Héctor Corrada Bravo, Tamara Casper, Carlo Colantuoni, Jonathan Crabtree, Heather H Creasy, Kirsten Crichton, Megan Crow, Nick Dee, Elizabeth L Dougherty, Wayne I Doyle, Sandrine Dudoit, Rongxin Fang, Victor Felix, Olivia Fong, Michelle G Giglio, Jeff Goldy, Michael J Hawrylycz, Brian R Herb, Ronna Hertzano, Xiaomeng Hou, Qiwen Hu, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Yang Eric Li, Jacinta D Lucero, Chongyuan Luo, Anup A Mahurkar, Delissa McMillen, Naeem M Nadaf, Joseph R Nery, Thuc Nghi Nguyen, Sheng-Yong Niu, Vasilis Ntranos, Joshua Orvis, Julia K Osteen, Trangthanh H Pham, António Pinto-Duarte, Olivier Poirion, Sebastian Preissl, Elizabeth Purdom, Christine Rimorin, Davide Risso, Angeline C Rivkin, Kimberly A Smith, Kelly Street, Josef Sulc, Valentine Svensson, Michael Tieu, Amy Torkelson, Herman Tung, Eeshit Dhaval Vaishnav, Charles R Vanderburg, Cindy T J van Velthoven, Xinxin Wang, Owen R White, Z Josh Huang, Peter V Kharchenko, Lior Pachter, John Ngai, Aviv Regev, Bosiljka Tasic, Joshua D Welch, Jesse Gillis, Evan Z Macosko, Bing Ren, Joseph R Ecker, Hongkui Zeng, Eran A Mukamel
A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex. Nature 598 (7879) (2021)
Daniela Di Bella, Ehsan Habibi, Robert R Stickels, Gabriele Scalia, Juliana Brown, Payman Yadollahpour, Sung Min Yang, Catherine Abbate, Tommaso Biancalani, Evan Z Macosko, Fei Chen, Aviv Regev, Paola Arlotta
Molecular logic of cellular diversification in the mouse cerebral cortex. Nature 595 (7868) (2021)
Evan Z Macosko
Single-cell RNA sequencing at isoform resolution. Nature biotechnology 38 (6) (2020)
Robert R Stickels, Evan Murray, Pawan Kumar, Jilong Li, Jamie L Marshall, Daniela Di Bella, Paola Arlotta, Evan Z Macosko, Fei Chen
Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2. Nature biotechnology 39 (3) (2020)
Samuel G Rodriques, Robert R Stickels, Aleksandrina Goeva, Caroline A Martin, Evan Murray, Charles R Vanderburg, Joshua Welch, Linlin M Chen, Fei Chen, Evan Z Macosko
Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution. Science (New York, N.Y.) 363 (6434) (2019)

Evan Z Macosko.css-eqlu8i{font-size:small;padding-left:4px;} (Evan Macosko)

Publication Activity (10 Years)

Top Topics

Top Venues

Evan Z Macosko (Evan Macosko)