Rainer H Kohler (Rainer Kohler)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 28

Top Topics

Combination Therapy

Metastatic Colorectal Cancer

Immune Response

Top Venues

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Nature communications

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Noah Enbergs, Elias A Halabi, Anne-Gaëlle Goubet, Kelton Schleyer, Ina R Fredrich, Rainer H Kohler, Christopher S Garris, Mikaël J Pittet, Ralph Weissleder
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (15) (2024)
Ina F Fredrich, Elias A Halabi, Rainer H Kohler, Xinying Ge, Christopher S Garris, Ralph Weissleder
Highly Active Myeloid Therapy for Cancer. ACS nano (2023)
Riddha Das, Elias A Halabi, Ina R Fredrich, Juhyun Oh, Hannah M Peterson, Xinying Ge, Ella Scott, Rainer H Kohler, Christopher S Garris, Ralph Weissleder
Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Jina Ko, Martin Wilkovitsch, Juhyun Oh, Rainer H Kohler, Evangelia Bolli, Mikaël J Pittet, Claudio Vinegoni, David Brian Sykes, Hannes Mikula, Ralph Weissleder, Jonathan C T Carlson
Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes. Nature biotechnology 40 (11) (2022)
Wolfram C Poller, Jeffrey Downey, Agnes A Mooslechner, Nargis Khan, Long Li, Christopher T Chan, Cameron S McAlpine, Chunliang Xu, Florian Kahles, Shun He, Henrike Janssen, John E Mindur, Sumnima Singh, Máté G Kiss, Laura Alonso-Herranz, Yoshiko Iwamoto, Rainer H Kohler, Lai Ping Wong, Kashish Chetal, Scott J Russo, Ruslan I Sadreyev, Ralph Weissleder, Matthias Nahrendorf, Paul Sylvain Frenette, Maziar Divangahi, Filip K Swirski
Brain motor and fear circuits regulate leukocytes during acute stress. Nature 607 (7919) (2022)
Thomas S C Ng, Hui-Yu Hu, Stefan Kronister, Chanseo Lee, Ran Li, Luca Gerosa, Sylwia A Stopka, Danielle M Burgenske, Ishaan Khurana, Michael S Regan, Sreeram Vallabhaneni, Niharika Putta, Ella Scott, Dylan Matvey, Anita Giobbie-Hurder, Rainer H Kohler, Jann N Sarkaria, Sareh Parangi, Peter Karl Sorger, Nathalie Y R Agar, Heather A Jacene, Ryan J Sullivan, Elizabeth Buchbinder, Hannes Mikula, Ralph Weissleder, Miles A Miller
Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy. Science advances 8 (17) (2022)
Jina Ko, Kilean Lucas, Rainer H Kohler, Elias A Halabi, Martin Wilkovitsch, Jonathan C T Carlson, Ralph Weissleder
In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 9 (24) (2022)
Marie Siwicki, Nicolas A Gort-Freitas, Marius Messemaker, Ruben Bill, Jeremy Gungabeesoon, Camilla Engblom, Rapolas Zilionis, Christopher Garris, Genevieve M Gerhard, Anna Kohl, Yunkang Lin, Angela E Zou, Chiara Cianciaruso, Evangelia Bolli, Christina Pfirschke, Yi-Jang Lin, Cécile Piot, John E Mindur, Nilesh P Talele, Rainer H Kohler, Yoshiko Iwamoto, Mari A Mino-Kenudson, Sara I Pai, Claudio deVito, Thibaud Koessler, Doron Merkler, Alexander Coukos, Alexandre Wicky, Montserrat Fraga, Christine Sempoux, Rakesh K Jain, Pierre-Yves Dietrich, Olivier Michielin, Ralph Weissleder, Allon M Klein, Mikaël J Pittet
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy. Science immunology 6 (61) (2022)
Christina Pfirschke, Rapolas Zilionis, Camilla Engblom, Marius Messemaker, Angela E Zou, Steffen Rickelt, Nicolas A Gort-Freitas, Yunkang Lin, Ruben Bill, Marie Siwicki, Jeremy Gungabeesoon, Melissa M Sprachman, Angela N Marquard, Christopher Blake Rodell, Michael F Cuccarese, Jeremy Quintana, Maaz S Ahmed, Rainer H Kohler, Virginia Savova, Ralph Weissleder, Allon M Klein, Mikael J Pittet
Macrophage-targeted therapy unlocks antitumoral crosstalk between IFN𝛾-secreting lymphocytes and IL12-producing dendritic cells. Cancer immunology research (2021)
Ran Li, Thomas S C Ng, Stephanie J Wang, Mark Prytyskach, Christopher Blake Rodell, Hannes Mikula, Rainer H Kohler, Michelle A Garlin, Douglas A Lauffenburger, Sareh Parangi, Daniela M Dinulescu, Nabeel Bardeesy, Ralph Weissleder, Miles A Miller
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer. Nature nanotechnology 16 (7) (2021)
Gaurav Luthria, Ran Li, Stephanie Wang, Mark Prytyskach, Rainer H Kohler, Douglas A Lauffenburger, Timothy J Mitchison, Ralph Weissleder, Miles A Miller
In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells. Nature communications 11 (1) (2020)
Stephanie J Wang, Ran Li, Thomas S C Ng, Gaurav Luthria, Madeleine J Oudin, Mark Prytyskach, Rainer H Kohler, Ralph Weissleder, Douglas A Lauffenburger, Miles A Miller
Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Science advances 6 (21) (2020)
Thomas S C Ng, Viswanath Gunda, Ran Li, Mark Prytyskach, Yoshiko Iwamoto, Rainer H Kohler, Sareh Parangi, Ralph Weissleder, Miles A Miller
Detecting Immune Response to Therapies Targeting PDL1 and BRAF by Using Ferumoxytol MRI and Macrin in Anaplastic Thyroid Cancer. Radiology 298 (1) (2020)
Maaz S Ahmed, Christopher Blake Rodell, Maarten Hulsmans, Rainer H Kohler, Aaron D Aguirre, Matthias Nahrendorf, Ralph Weissleder
A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjugate chemistry 30 (3) (2019)
Peter David Koch, Maaz S Ahmed, Rainer H Kohler, Ran Li, Ralph Weissleder
Imaging of Tie2 with a Fluorescently Labeled Small Molecule Affinity Ligand. ACS chemical biology 15 (1) (2019)
Miles A Miller, Ravi Chandra, Michael F Cuccarese, Christina Pfirschke, Camilla Engblom, Shawn Stapleton, Utsarga Adhikary, Rainer H Kohler, James F Mohan, Mikaël J Pittet, Ralph Weissleder
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts. Science translational medicine 9 (392) (2018)
Miles A Miller, Hannes Mikula, Gaurav Luthria, Ran Li, Stefan Kronister, Mark Prytyskach, Rainer H Kohler, Timothy Mitchison, Ralph Weissleder
Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. ACS nano 12 (12) (2018)
Christopher B Rodell, Sean Philip Arlauckas, Michael F Cuccarese, Christopher S Garris, Ran Li, Maaz S Ahmed, Rainer H Kohler, Mikael J Pittet, Ralph Weissleder
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature biomedical engineering 2 (8) (2018)
Hye-Yeong Kim, Ran Li, Thomas S C Ng, Gabriel Courties, Christopher Blake Rodell, Mark Prytyskach, Rainer H Kohler, Mikaël J Pittet, Matthias Nahrendorf, Ralph Weissleder, Miles A Miller
Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin. ACS nano 12 (12) (2018)
Sean Philip Arlauckas, Christopher S Garris, Rainer H Kohler, Maya Kitaoka, Michael F Cuccarese, Katherine S Yang, Miles A Miller, Jonathan C Carlson, Gordon J Freeman, Robert M Anthony, Ralph Weissleder, Mikaël J Pittet
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Science translational medicine 9 (389) (2018)
Kevin R King, Aaron D Aguirre, Yu-Xiang Ye, Yuan Sun, Jason D Roh, Richard P Ng, Rainer H Kohler, Sean P Arlauckas, Yoshiko Iwamoto, Andrej Savol, Ruslan I Sadreyev, Mark Kelly, Timothy P Fitzgibbons, Katherine A Fitzgerald, Timothy Mitchison, Peter Libby, Matthias Nahrendorf, Ralph Weissleder
IRF3 and type I interferons fuel a fatal response to myocardial infarction. Nature medicine 23 (12) (2017)
Miles A Miller, Bjorn Askevold, Hannes Mikula, Rainer H Kohler, David Pirovich, Ralph Weissleder
Nano-palladium is a cellular catalyst for in vivo chemistry. Nature communications 8 (2017)
Miles A Miller, Yao-Rong Zheng, Suresh Gadde, Christina Pfirschke, Harshal Zope, Camilla Engblom, Rainer H Kohler, Yoshiko Iwamoto, Katherine S Yang, Bjorn Askevold, Nagesh Kolishetti, Mikael Pittet, Stephen J Lippard, Omid C Farokhzad, Ralph Weissleder
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nature communications 6 (2015)