Moritz Gerstung (M Gerstung)

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 44

Top Venues

Nature communications

Nature genetics

Nature

Nature cancer

European Bioinformatics Institute

ETH Zurich (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

European Bioinformatics Institute Aug 01 2015

United Kingdom

Research Group Leader

Wellcome Trust Sanger Institute Jun 18 2012 - Jun 17 2015

United Kingdom

Postdoctoral Fellow :: Cancer Genome Project

Education History

ETH Zurich Apr 01 2008 - Mar 31 2012

Switzerland

PHD

Publications

Darui Jin, Shangying Liang, Artem Shmatko, Alexander Arnold, David Horst, Thomas G P Grünewald, Moritz Gerstung, Xiangzhi Bai
Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides. Nature communications 15 (1) (2024)
Darui Jin, Shangying Liang, Artem Shmatko, Alexander Arnold, David Horst, Thomas G P Grünewald, Moritz Gerstung, Xiangzhi Bai
Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides. Nature communications 15 (1) (2024)
Darui Jin, Shangying Liang, Artem Shmatko, Alexander Arnold, David Horst, Thomas G P Grünewald, Moritz Gerstung, Xiangzhi Bai
Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides. Nature communications 15 (1) (2024)
Darui Jin, Shangying Liang, Artem Shmatko, Alexander Arnold, David Horst, Thomas G P Grünewald, Moritz Gerstung, Xiangzhi Bai
Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides. Nature communications 15 (1) (2024)
Darui Jin, Shangying Liang, Artem Shmatko, Alexander Arnold, David Horst, Thomas G P Grünewald, Moritz Gerstung, Xiangzhi Bai
Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides. Nature communications 15 (1) (2024)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
José Guilherme de Almeida, Emma Gudgin, Martin Besser, William G Dunn, Jonathan Cooper, Torsten Haferlach, George S Vassiliou, Moritz Gerstung
Computational analysis of peripheral blood smears detects disease-associated cytomorphologies. Nature communications 14 (1) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics (2023)
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jordan R Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B Alexandrov, Gino R Somers, Joshua D Schiffman, Varda Rotter, David Malkin, Adam Shlien
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature communications 14 (1) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Emilie Abby, Stefan C Dentro, Michael W J Hall, Joanna C Fowler, Swee Hoe Ong, Roshan K Sood, Albert Herms, Gabriel Piedrafita, Irina Abnizova, Christian W Siebel, Moritz Gerstung, Michael W J Hall, Philip H Jones
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth. Nature genetics 55 (2) (2023)
Jonas Demeulemeester, Stefan C Dentro, Moritz Gerstung, Peter Van Loo
Biallelic mutations in cancer genomes reveal local mutational determinants. Nature genetics 54 (2) (2022)
Zaira Seferbekova, Artem Lomakin, Lucy R Yates, Moritz Gerstung
Spatial biology of cancer evolution. Nature reviews. Genetics (2022)
Margarete A Fabre, José Guilherme de Almeida, Edoardo Fiorillo, Emily Mitchell, Aristi Damaskou, Justyna Rak, Valeria Orrù, Michele Marongiu, Michael Spencer Chapman, M S Vijayabaskar, Joanna Baxter, Claire Hardy, Federico Abascal, Nicholas O Williams, Jyoti Nangalia, Iñigo Martincorena, Peter J Campbell, Eoin F McKinney, Francesco Cucca, Moritz Gerstung, George S Vassiliou
The longitudinal dynamics and natural history of clonal haematopoiesis. Nature 606 (7913) (2022)
Artem Lomakin, Jessica Svedlund, Carina Strell, Milana Gataric, Artem Shmatko, Gleb Rukhovich, Jun Sung Park, Young Seok Ju, Stefan C Dentro, Vitalii Kleshchevnikov, Vasyl Vaskivskyi, Tong Li, Omer Ali Bayraktar, Sarah E Pinder, Andrea L Richardson, Sandro Santagata, Peter J Campbell, Hege Russnes, Moritz Gerstung, Mats Nilsson, Lucy R Yates
Spatial genomics maps the structure, nature and evolution of cancer clones. Nature 611 (7936) (2022)
Kasumi Murai, Stefan C Dentro, Swee Hoe Ong, Roshan K Sood, David Fernandez-Antoran, Albert Herms, Vasiliki Kostiou, Irina Abnizova, Michael W J Hall, Moritz Gerstung, Philip H Jones
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition. Nature communications 13 (1) (2022)
Artem Shmatko, Narmin Ghaffari Laleh, Moritz Gerstung, Jakob Nikolas Kather
Artificial intelligence in histopathology: enhancing cancer research and clinical oncology. Nature cancer 3 (9) (2022)
Alex T J Cagan, Adrian Baez-Ortega, Natalia Brzozowska, Federico Abascal, Tim H H Coorens, Mathijs A Sanders, Andrew R J Lawson, Luke M R Harvey, Shriram Bhosle, David Jones, Raul E Alcantara, Timothy M Butler, Yvette Hooks, Kirsty Roberts, Elizabeth Anderson, Sharna Lunn, Edmund Flach, Simon Spiro, Inez Januszczak, Ethan Wrigglesworth, Hannah Jenkins, Tilly Dallas, Nic Masters, Matthew W Perkins, Robert Deaville, Megan Druce, Ruzhica Bogeska, Michael D Milsom, Björn Neumann, Frank Gorman, Fernando Constantino-Casas, Laura Peachey, Diana Bochynska, Ewan St John Smith, Moritz Gerstung, Peter J Campbell, Elizabeth P Murchison, Michael R Stratton, Iñigo Martincorena
Somatic mutation rates scale with lifespan across mammals. Nature 604 (7906) (2022)
Vitalii Kleshchevnikov, Artem Shmatko, Emma Dann, Alexander Aivazidis, Hamish W King, Tong Li, Rasa Elmentaite, Artem Lomakin, Veronika Kedlian, Adam Gayoso, Mika Sarkin Jain, Jun Sung Park, Lauma Ramona, Elizabeth Tuck, Anna Arutyunyan, Roser Vento-Tormo, Moritz Gerstung, Louisa Katherine James, Oliver Stegle, Omer Ali Bayraktar
Cell2location maps fine-grained cell types in spatial transcriptomics. Nature biotechnology 40 (5) (2022)
Federico Abascal, Luke M R Harvey, Emily Mitchell, Andrew R J Lawson, Stefanie V Lensing, Peter Ellis, Andrew J C Russell, Raul E Alcantara, Adrian Baez-Ortega, Yichen Wang, Eugene Jing Kwa, Henry Lee-Six, Alex T J Cagan, Tim H H Coorens, Michael Spencer Chapman, Sigurgeir Olafsson, Steven Leonard, David Jones, Heather E Machado, Megan Davies, Nina F Øbro, Krishnaa T A Mahbubani, Kieren Allinson, Moritz Gerstung, Kourosh Saeb Parsy, David G Kent, Elisa Laurenti, Michael R Stratton, Raheleh Rahbari, Peter J Campbell, Robert J Osborne, Iñigo Martincorena
Somatic mutation landscapes at single-molecule resolution. Nature 593 (7859) (2021)
Bartomeu Colom, A Herms, Michael W J Hall, Stefan C Dentro, Charlotte King, R K Sood, Maria P Alcolea, Gabriel Piedrafita, David Fernandez-Antoran, Swee Hoe Ong, Joanna C Fowler, Krishnaa T A Mahbubani, Kourosh Saeb Parsy, Moritz Gerstung, Michael W J Hall, Philip H Jones
Mutant clones in normal epithelium outcompete and eliminate emerging tumours. Nature 598 (7881) (2021)
Harald S Vöhringer, Theo Sanderson, Matthew Sinnott, Nicola De Maio, Thuy Nguyen, Richard J Goater, Frank Schwach, Ian Harrison, Joel Hellewell, Cristina V Ariani, Sonia Gonçalves, David K Jackson, Ian Johnston, Alexander W Jung, Callum Saint, John Sillitoe, Maria Suciu, Nick Goldman, Jasmina Panovska-Griffiths, null null, null null, Ewan Birney, Erik M Volz, Sebastian Funk, Dominic P Kwiatkowski, Meera Chand, Iñigo Martincorena, Jeffrey C Barrett, Moritz Gerstung
Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature (2021)
Nathaniel D Anderson, Yael Babichev, Fabio Fuligni, Federico Comitani, Mehdi Layeghifard, Rosemarie E Venier, Stefan C Dentro, Anant Maheshwari, Sheena Guram, Claire Wunker, J Drew Thompson, Kyoko E Yuki, Huayun Hou, Matthew Zatzman, Nicholas Light, Marcus Q Bernardini, Jay S Wunder, Irene L Andrulis, Peter Ferguson, Albiruni R Abdul Razak, Carol J Swallow, James J Dowling, Rima S Al-Awar, Richard Marcellus, Marjan Rouzbahman, Moritz Gerstung, Daniel Durocher, Ludmil B Alexandrov, Brendan C Dickson, Rebecca A Gladdy, Adam Shlien
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival. Nature communications 12 (1) (2021)
Harald Vöhringer, Arne Van Hoeck, Edwin Cuppen, Moritz Gerstung
Learning mutational signatures and their multidimensional genomic properties with TensorSignatures. Nature communications 12 (1) (2021)
Kadir C Akdemir, Victoria T Le, Justin M Kim, Sarah Killcoyne, Devin A King, Ya-Ping Lin, Yanyan Tian, Akira Inoue, Samirkumar B Amin, Frederick S Robinson, Manjunath Nimmakayalu, Rafael E Herrera, Erica J Lynn, Kin Chan, Sahil B Seth, Leszek J Klimczak, Moritz Gerstung, Dmitry A Gordenin, John O'Brien, Lei Li, Yonathan Lissanu Deribe, Roel G W Verhaak, Peter J Campbell, Rebecca C Fitzgerald, Ashby J Morrison, Jesse R Dixon, P Andrew Futreal
Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure. Nature genetics 52 (11) (2020)
Andrew R J Lawson, Federico Abascal, Tim H H Coorens, Yvette Hooks, Laura O'Neill, Calli Latimer, Keiran M Raine, Mathijs Arnoud Sanders, Anne Y Warren, Krishnaa T A Mahbubani, Bethany Bareham, Timothy M Butler, Luke M R Harvey, Alex T J Cagan, Andrew Menzies, Luiza Moore, Alexandra J Colquhoun, William Turner, Benjamin C Thomas, Vincent Gnanapragasam, Nicholas O Williams, Doris M Rassl, Harald Vöhringer, Sonia Zumalave, Jyoti Nangalia, Jose M C Tubio, Moritz Gerstung, Kourosh Saeb Parsy, Michael R Stratton, Peter J Campbell, Thomas J Mitchell, Iñigo Martincorena
Extensive heterogeneity in somatic mutation and selection in the human bladder. Science (New York, N.Y.) 370 (6512) (2020)
Nadezda V Volkova, Bettina Meier, Víctor González-Huici, Simone Bertolini, Santiago Gonzalez, Harald Vöhringer, Federico Abascal, Iñigo Martincorena, Peter J Campbell, Anton Gartner, Moritz Gerstung
Mutational signatures are jointly shaped by DNA damage and repair. Nature communications 11 (1) (2020)
Sarah Killcoyne, Eleanor Gregson, David C Wedge, Dan J Woodcock, Matthew D Eldridge, Rachel de la Rue, Ahmad Miremadi, Sujath Abbas, Adrienn Blasko, Cassandra Kosmidou, Władysław Januszewicz, Aikaterini Varanou Jenkins, Moritz Gerstung, Rebecca C Fitzgerald
Genomic copy number predicts esophageal cancer years before transformation. Nature medicine 26 (11) (2020)
Bartomeu Colom, Maria P Alcolea, Gabriel Piedrafita, Michael W J Hall, Agnieszka Wabik, Stefan C Dentro, Joanna C Fowler, Albert Herms, Charlotte King, Swee Hoe Ong, Roshan K Sood, Moritz Gerstung, Inigo Martincorena, Michael W J Hall, Philip H Jones
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium. Nature genetics 52 (6) (2020)
Yu Fu, Alexander W Jung, Ramon Viñas Torne, Santiago Gonzalez, Harald Vöhringer, Artem Shmatko, Lucy R Yates, Mercedes Jimenez-Linan, Luiza Moore, Moritz Gerstung
Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis. Nature cancer 1 (8) (2020)
Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Głodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth C Anderson, Jose M C Tubio, David C Wedge, Moritz Gerstung, Hervé Avet-Loiseau, Nikhil Munshi, Peter J Campbell
Genomic landscape and chronological reconstruction of driver events in multiple myeloma. Nature communications 10 (1) (2019)
Maxime Tarabichi, Iñigo Martincorena, Moritz Gerstung, Armand M Leroi, Florian Markowetz, null null, Paul T Spellman, Quaid D Morris, Ole Christian Lingjærde, David C Wedge, Peter Van Loo
Neutral tumor evolution? Nature genetics 50 (12) (2019)
Lucy R Yates, Moritz Gerstung, Stian Knappskog, Christine Desmedt, Gunes Gundem, Peter Van Loo, Turid Aas, Ludmil B Alexandrov, Denis Larsimont, Helen Davies, Yilong Li, Young Seok Ju, Manasa Ramakrishna, Hans Kristian Haugland, Peer Kaare Lilleng, Serena Nik-Zainal, Stuart McLaren, Adam Butler, Sancha Martin, Dominic Glodzik, Andrew Menzies, Keiran M Raine, Jonathan Hinton, David Jones, Laura J Mudie, Bing Jiang, Delphine Vincent, April Greene-Colozzi, Pierre-Yves Adnet, Aquila Fatima, Marion Maetens, Michail Ignatiadis, Michael R Stratton, Christos Sotiriou, Andrea L Richardson, Per Eystein Lønning, David C Wedge, Peter J Campbell
Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nature medicine 21 (7) (2015)
Adam Shlien, Brittany B Campbell, Richard de Borja, Ludmil B Alexandrov, Daniele Merico, David Wedge, Peter Van Loo, Patrick S Tarpey, Paul Coupland, Sam Behjati, Aaron Pollett, Tatiana Lipman, Abolfazl Heidari, Shriya Deshmukh, Na'ama Avitzur, Bettina Meier, Moritz Gerstung, Ye Hong, Diana M Merino, Manasa Ramakrishna, Marc Remke, Roland Arnold, Gagan B Panigrahi, Neha P Thakkar, Karl P Hodel, Erin E Henninger, A Yasemin Göksenin, Doua Bakry, George S Charames, Harriet Druker, Jordan Lerner-Ellis, Matthew Mistry, Rina Dvir, Ronald Grant, Ronit Elhasid, Roula Farah, Glenn P Taylor, Paul C Nathan, Sarah Alexander, Shay Ben-Shachar, Simon C Ling, Steven Gallinger, Shlomi Constantini, Peter Dirks, Annie Huang, Stephen W Scherer, Richard G Grundy, Carol Durno, Melyssa Aronson, Anton Gartner, M Stephen Meyn, Michael D Taylor, Zachary F Pursell, Christopher E Pearson, David Malkin, P Andrew Futreal, Michael R Stratton, Eric Bouffet, Cynthia Hawkins, Peter J Campbell, Uri Tabori, null null
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers. Nature genetics 47 (3) (2015)

Moritz Gerstung.css-eqlu8i{font-size:small;padding-left:4px;} (M Gerstung)

Publication Activity (10 Years)

Top Topics

Top Venues

Moritz Gerstung (M Gerstung)