Floris Foijer

Scopus Author ID DAI ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 83

Top Topics

Histone Deacetylase

Endometrial Cancer

Top Venues

Nature communications

The EMBO journal

Life science alliance

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Andréa E Tijhuis, Floris Foijer
Characterizing chromosomal instability-driven cancer evolution and cell fitness at a glance. Journal of cell science 137 (1) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports 25 (6) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Sangita Choudhury, Indu Sivankutty, Youngsook Lucy Jung, August Yue Huang, Sarah Araten, Connor Kenny, Zheming An, Ryan Doan, Floris Foijer, Erica Matsu, Ila Rosen, Jack H Marciano, Asish Jain, Liang Sun, Nazia Hilal, Eunjung Alice Lee, Christopher A Walsh, Ming Chen
Single-nucleus multi-omic profiling of polyploid heart nuclei identifies fusion-derived cardiomyocytes in the human heart. Research square (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports 25 (6) (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient cancer cell phenotype is acquired via polyploidization associated with early stress response coupled to HIF-2α transcriptional regulation. Cancer research communications (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Anneke L Eerkens, Koen Brummel, Annegé Vledder, Sterre T Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M de Lange, Rie Klomp, David N Church, Arja Ter Elst, Rene Wardenaar, Diana Carolina Johanna Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K L Reyners, Marco de Bruyn, Hans W Nijman
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study. Nature communications 15 (1) (2024)
Andréa E Tijhuis, Floris Foijer
Characterizing chromosomal instability-driven cancer evolution and cell fitness at a glance. Journal of cell science 137 (1) (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Anneke L Eerkens, Koen Brummel, Annegé Vledder, Sterre T Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M de Lange, Rie Klomp, David N Church, Arja Ter Elst, Rene Wardenaar, Diana Carolina Johanna Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K L Reyners, Marco de Bruyn, Hans W Nijman
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study. Nature communications 15 (1) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Sangita Choudhury, Indu Sivankutty, Youngsook Lucy Jung, August Yue Huang, Sarah Araten, Connor Kenny, Zheming An, Ryan Doan, Floris Foijer, Erica Matsu, Ila Rosen, Jack H Marciano, Asish Jain, Liang Sun, Nazia Hilal, Eunjung Alice Lee, Christopher A Walsh, Ming Chen
Single-nucleus multi-omic profiling of polyploid heart nuclei identifies fusion-derived cardiomyocytes in the human heart. Research square (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports 25 (6) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Andréa E Tijhuis, Floris Foijer
Characterizing chromosomal instability-driven cancer evolution and cell fitness at a glance. Journal of cell science 137 (1) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports (2024)
Sangita Choudhury, Indu Sivankutty, Youngsook Lucy Jung, August Yue Huang, Sarah Araten, Connor Kenny, Zheming An, Ryan Doan, Floris Foijer, Erica Matsu, Ila Rosen, Jack H Marciano, Asish Jain, Liang Sun, Nazia Hilal, Eunjung Alice Lee, Christopher A Walsh, Ming Chen
Single-nucleus multi-omic profiling of polyploid heart nuclei identifies fusion-derived cardiomyocytes in the human heart. Research square (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Amanda Faria Assoni, Erika N Guerrero, René Wardenaar, Danyllo Oliveira, Petra L Bakker, Luciana M Alves, Valdemir Melechco Carvalho, Oswaldo Keith Okamoto, Mayana Zatz, Floris Foijer
IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated amyotrophic lateral sclerosis. Brain pathology (Zurich, Switzerland) (2023)
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk Hg Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen A A Nollen
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. Life science alliance 6 (7) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
Lavinia Spain, Alexander Coulton, Irene Lobon, Andrew Rowan, Desiree Schnidrig, Scott T C Shepherd, Benjamin Shum, Fiona Byrne, Maria Goicoechea, Elisa Piperni, Lewis Au, Kim Edmonds, Eleanor Carlyle, Nikki Hunter, Alexandra Renn, Christina Messiou, Peta Hughes, Jaime Nobbs, Floris Foijer, Hilda van den Bos, Rene Wardenaar, Diana Carolina Johanna Spierings, Charlotte Spencer, Andreas Michael Schmitt, Zayd Tippu, Karla Lingard, Lauren Grostate, Kema Peat, Kayleigh Kelly, Sarah Sarker, Sarah Vaughan, Mary Mangwende, Lauren Terry, Denise Kelly, Jennifer Biano, Aida Murra, Justine Korteweg, Charlotte Lewis, Molly OFlaherty, Anne-Laure Cattin, Max Emmerich, Camille L Gerard, Husayn Ahmed Pallikonda, Joanna Lynch, Robert Mason, Aljosja Rogiers, Hang Xu, Ariana Huebner, Nicholas McGranahan, Maise Al Bakir, Jun Murai, Cristina Naceur-Lombardelli, Elaine Borg, Miriam Mitchison, David Allan Moore, Mary Falzon, Ian Proctor, Gordon W H Stamp, Emma L Nye, Kate Young, Andrew J S Furness, Lisa M Pickering, Ruby Stewart, Ula Mahadeva, Anna C Green, James M G Larkin, Kevin Litchfield, Charles Swanton, Mariam Jamal-Hanjani, Samra Turajlic
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways. Cancer discovery (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk Hg Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen A A Nollen
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. Life science alliance 6 (7) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk Hg Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen A A Nollen
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. Life science alliance 6 (7) (2023)
Eleanor L Woodward, Minjun Yang, Larissa Helena Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Diana Carolina Johanna Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Nature communications 14 (1) (2023)
Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, Rene Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nicholas Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature communications 14 (1) (2023)
Laura Tovini, Sarah C Johnson, Molly A Guscott, Alexander M Andersen, Diana Carolina Johanna Spierings, Rene Wardenaar, Floris Foijer, Sarah E McClelland
Targeted assembly of ectopic kinetochores to induce chromosome-specific segmental aneuploidies. The EMBO journal (2023)
Amanda Faria Assoni, Thiago Giove Mitsugi, René Wardenaar, Raiane Oliveira Ferreira, Elisa Helena Farias Jandrey, Gabriela Machado Novaes, Isabela Fonseca de Oliveira Granha, Petra L Bakker, Carolini Kaid, Mayana Zatz, Floris Foijer, Oswaldo Keith Okamoto
Neurodegeneration-associated protein VAPB regulates proliferation in medulloblastoma. Scientific reports 13 (1) (2023)
Eleanor L Woodward, Minjun Yang, Larissa Helena Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Diana Carolina Johanna Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Nature communications 14 (1) (2023)
Eleanor L Woodward, Minjun Yang, Larissa Helena Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Diana Carolina Johanna Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Nature communications 14 (1) (2023)
My Anh Truong, Paula Cané-Gasull, Sippe G de Vries, Wilco Nijenhuis, Rene Wardenaar, Lukas C Kapitein, Floris Foijer, Susanne M A Lens
A kinesin-based approach for inducing chromosome-specific mis-segregation in human cells. The EMBO journal (2023)
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk Hg Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen A A Nollen
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. Life science alliance 6 (7) (2023)
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk Hg Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen A A Nollen
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. Life science alliance 6 (7) (2023)
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Liesbeth Harkema, Sameh A Youssef, Natalie Beschorner, Anouk Hg Wolters, Bjorn Bakker, Lore Becker, Lilian Garrett, Susan Marschall, Sabine M Hoelter, Wolfgang Wurst, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Amantha Thathiah, Floris Foijer, Bart van de Sluis, Jan van Deursen, Matthias Jucker, Alain de Bruin, Ellen A A Nollen
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain. Life science alliance 6 (7) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine (2023)
Siqi Zheng, Erika Guerrero-Haughton, Floris Foijer
Chromosomal Instability-Driven Cancer Progression: Interplay with the Tumour Microenvironment and Therapeutic Strategies. Cells 12 (23) (2023)
Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, Rene Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nicholas Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature communications 14 (1) (2023)
Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, Rene Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nicholas Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature communications 14 (1) (2023)
Simon Gemble, Rene Wardenaar, Kristina Keuper, Nishit Srivastava, Maddalena Nano, Anne-Sophie Macé, Andréa E Tijhuis, Sara Vanessa Bernhard, Diana Carolina Johanna Spierings, Anthony Simon, Oumou Goundiam, Helfrid Hochegger, Matthieu Piel, Floris Foijer, Zuzana Storchová, Renata Basto
Genetic instability from a single S phase after whole-genome duplication. Nature 604 (7904) (2022)
Christy Hong, Michael Schubert, Andréa E Tijhuis, Marta Requesens, Maurits Roorda, Anouk van den Brink, Lorena Andrade Ruiz, Petra L Bakker, Tineke van der Sluis, Wietske Pieters, Mengting Chen, Rene Wardenaar, Bert Van der Vegt, Diana Carolina Johanna Spierings, Marco de Bruyn, Marcel A T M van Vugt, Floris Foijer
cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers. Nature 607 (7918) (2022)
Irena Bočkaj, Tosca E I Martini, Marlinde J Smit, Inna Armandari, Bjorn Bakker, René Wardenaar, Tiny G J Meeuwsen-de Boer, Petra L Bakker, Diana Carolina Johanna Spierings, Eelco W Hoving, Victor Guryev, Floris Foijer, Sophia W M Bruggeman
Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum. International journal of molecular sciences 23 (17) (2022)
Sjoerd J Klaasen, My Anh Truong, Richard H van Jaarsveld, Isabella Koprivec, Valentina Štimac, Sippe G de Vries, Patrik Risteski, Snježana Kodba, Kruno Vukušić, Kim L de Luca, Joana F Marques, Elianne M Gerrits, Bjorn Bakker, Floris Foijer, Jop Kind, Iva M Tolić, Susanne M A Lens, Geert J P L Kops
Nuclear chromosome locations dictate segregation error frequencies. Nature 607 (7919) (2022)
Adriana Mañas, Kristina Aaltonen, Natalie Andersson, Karin Hansson, Aleksandra Adamska, Alexandra Seger, Hiroaki Yasui, Hilda van den Bos, Katarzyna Radke, Javanshir Esfandyari, Madhura Satish Bhave, Jenny Karlsson, Diana Carolina Johanna Spierings, Floris Foijer, David Gisselsson, Daniel Bexell
Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance. Science advances 8 (43) (2022)
Lin Zhou, Siqi Zheng, Fernando Rodrigo Rosas Bringas, Bjorn Bakker, Judith E Simon, Petra L Bakker, Hinke G Kazemier, Michael Schubert, Maurits Roorda, Marcel A T M van Vugt, Michael Chang, Floris Foijer
A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers. G3 (Bethesda, Md.) 11 (12) (2022)
Laura J Jilderda, Lin Zhou, Floris Foijer
Understanding How Genetic Mutations Collaborate with Genomic Instability in Cancer. Cells 10 (2) (2021)
Yael Cohen-Sharir, James M McFarland, Mai Abdusamad, Carolyn Marquis, Sara V Bernhard, Mariya Kazachkova, Helen Tang, Marica R Ippolito, Kathrin Laue, Johanna Zerbib, Heidi L H Malaby, Andrew Jones, Lisa-Marie Stautmeister, Irena Bockaj, René Wardenaar, Nicholas Lyons, Ankur K Nagaraja, Adam J Bass, Diana Carolina Johanna Spierings, Floris Foijer, Rameen Beroukhim, Stefano Santaguida, Todd R Golub, Jason Stumpff, Zuzana Storchová, Uri Ben-David
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition. Nature 590 (7846) (2021)
Ofer Shoshani, Bjorn Bakker, Lauren de Haan, Andréa E Tijhuis, Yin Wang, Dong Hyun Kim, Marcus Maldonado, Matthew A Demarest, Jon Artates, Ouyang Zhengyu, Adam Mark, René Wardenaar, Roman Sasik, Diana C J Spierings, Benjamin Vitre, Kathleen Fisch, Floris Foijer, Don W Cleveland
Transient genomic instability drives tumorigenesis through accelerated clonal evolution. Genes & development 35 (15-16) (2021)
Daniel Bronder, Anthony Tighe, Darawalee Wangsa, Dali Zong, Thomas J Meyer, René Wardenaar, Paul Minshall, Daniela Hirsch, Kerstin Heselmeyer-Haddad, Louisa Nelson, Diana Carolina Johanna Spierings, Joanne C McGrail, Maggie Cam, André Nussenzweig, Floris Foijer, Thomas Ried, Stephen S Taylor
TP53 loss initiates chromosomal instability in fallopian tube epithelial cells. Disease models & mechanisms 14 (11) (2021)
Klaske M Schukken, Yu-Chih Lin, Petra L Bakker, Michael Schubert, Stephanie F Preuß, Judith E Simon, Hilda van den Bos, Zuzana Storchová, Maria Colomé-Tatché, Holger Bastians, Diana Carolina Johanna Spierings, Floris Foijer
Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition. Life science alliance 3 (2) (2020)
Valentina C Sladky, Katja Knapp, Tamas G Szabo, Vincent Z Braun, Laura Bongiovanni, Hilda van den Bos, Diana Cj Spierings, Bart Westendorp, Ana Curinha, Tatjana Stojakovic, Hubert Scharnagl, Gerald Timelthaler, Kaoru Tsuchia, Matthias Pinter, Georg Semmler, Floris Foijer, Alain de Bruin, Thomas Reiberger, Nataliya Rohr-Udilova, Andreas Villunger
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis. EMBO reports 21 (12) (2020)
Louisa Nelson, Anthony Tighe, Anya Golder, Samantha Littler, Bjorn Bakker, Daniella Moralli, Syed Murtuza Baker, Ian J Donaldson, Diana Carolina Johanna Spierings, René Wardenaar, Bethanie Neale, George J Burghel, Brett Winter-Roach, Richard Edmondson, Andrew R Clamp, Gordon C Jayson, Sudha Desai, Catherine M Green, Andrew Hayes, Floris Foijer, Robert D Morgan, Stephen S Taylor
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity. Nature communications 11 (1) (2020)
Thao P Phan, Aubrey L Maryniak, Christina A Boatwright, Junsu Lee, Alisa Atkins, Andrea Tijhuis, Diana Cj Spierings, Hisham Bazzi, Floris Foijer, Philip W Jordan, Travis H Stracker, Andrew Jon Holland
Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway. The EMBO journal 40 (1) (2020)
Ana C F Bolhaqueiro, Bas Ponsioen, Bjorn Bakker, Sjoerd J Klaasen, Emre Kucukkose, Richard H van Jaarsveld, Judith Vivié, Ingrid Verlaan-Klink, Nizar Hami, Diana C J Spierings, Nobuo Sasaki, Devanjali Dutta, Sylvia F Boj, Robert G J Vries, Peter M Lansdorp, Marc van de Wetering, Alexander van Oudenaarden, Hans Clevers, Onno Kranenburg, Floris Foijer, Hugo J G Snippert, Geert J P L Kops
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids. Nature genetics 51 (5) (2019)
Christy Hong, Andrea E Tijhuis, Floris Foijer
The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability. Cells 8 (10) (2019)
Bente Benedict, Tanja van Harn, Marleen Dekker, Simone Hermsen, Asli Kucukosmanoglu, Wietske Pieters, Elly Delzenne-Goette, Josephine C Dorsman, Eva Petermann, Floris Foijer, Hein Te Riele
Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells. eLife 7 (2018)
Joana Catarina Macedo, Sara Vaz, Bjorn Bakker, Rui Ribeiro, Petra Lammigje Bakker, Jose Miguel Escandell, Miguel Godinho Ferreira, René Medema, Floris Foijer, Elsa Logarinho
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence. Nature communications 9 (1) (2018)
Stephanie E van Gijn, Elles Wierenga, Nathalie van den Tempel, Yannick P Kok, Anne Margriet Heijink, Diana C J Spierings, Floris Foijer, Marcel A T M van Vugt, Rudolf S N Fehrmann
TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells. Oncogene 38 (6) (2018)
Irena Bockaj, Sophia W M Bruggeman, Floris Foijer
Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140). BioEssays : news and reviews in molecular, cellular and developmental biology 39 (7) (2017)
Klaske M Schukken, Floris Foijer
CIN and Aneuploidy: Different Concepts, Different Consequences. BioEssays : news and reviews in molecular, cellular and developmental biology 40 (1) (2017)
Floris Foijer, Lee A Albacker, Bjorn Bakker, Diana C Spierings, Ying Yue, Stephanie Z Xie, Stephanie Davis, Annegret Lutum-Jehle, Darin Takemoto, Brian Hare, Brinley Furey, Roderick T Bronson, Peter M Lansdorp, Allan Bradley, Peter K Sorger
Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma. eLife 6 (2017)
Pepijn M Schoonen, Francien Talens, Colin Stok, Ewa Gogola, Anne Margriet Heijink, Peter Bouwman, Floris Foijer, Madalena Tarsounas, Sohvi Blatter, Jos Jonkers, Sven Rottenberg, Marcel A T M van Vugt
Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells. Nature communications 8 (2017)