Diana Carolina Johanna Spierings (Diana C J Spierings, Diana Spierings, Diana Cj Spierings)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 75

Top Topics

Endometrial Cancer

Circulating Tumor

Top Venues

Nature communications

Science advances

The EMBO journal

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Valeria Piattelli, Roberta Bartucci, Catharina Reker-Smit, Sander de Weerd, Christoffer Åberg, Victor Guryev, Diana Carolina Johanna Spierings, Anna Salvati
Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing. Nature nanotechnology 19 (7) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports 25 (6) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Valeria Piattelli, Roberta Bartucci, Catharina Reker-Smit, Sander de Weerd, Christoffer Åberg, Victor Guryev, Diana Carolina Johanna Spierings, Anna Salvati
Author Correction: Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing. Nature nanotechnology (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports 25 (6) (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient cancer cell phenotype is acquired via polyploidization associated with early stress response coupled to HIF-2α transcriptional regulation. Cancer research communications (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Valeria Piattelli, Roberta Bartucci, Catharina Reker-Smit, Sander de Weerd, Christoffer Åberg, Victor Guryev, Diana Carolina Johanna Spierings, Anna Salvati
Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing. Nature nanotechnology (2024)
Anneke L Eerkens, Koen Brummel, Annegé Vledder, Sterre T Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M de Lange, Rie Klomp, David N Church, Arja Ter Elst, Rene Wardenaar, Diana Carolina Johanna Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K L Reyners, Marco de Bruyn, Hans W Nijman
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study. Nature communications 15 (1) (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Saskia Sydow, Paul Piccinelli, Shamik Mitra, Panagiotis Tsagkozis, Asle Charles Hesla, Camila B R De Mattos, Jan Köster, Linda Magnusson, Jenny Nilsson, Adam Ameur, Rene Wardenaar, Floris Foijer, Diana Carolina Johanna Spierings, Fredrik Mertens
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma. Communications biology 7 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Christopher Carroll, Auraya Manaprasertsak, Arthur Boffelli Castro, Hilda van den Bos, Diana Carolina Johanna Spierings, Rene Wardenaar, Anuraag Bukkuri, Niklas Engström, Etienne Baratchart, Minjun Yang, Andrea Biloglav, Charlie Kinahan Cornwallis, Bertil Johansson, Catharina Hagerling, Marie Arsenian Henriksson, Kajsa Paulsson, Sarah R Amend, Sofie Mohlin, Floris Foijer, Alan McIntyre, Kenneth J Pienta, Emma U Hammarlund
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer research communications 4 (3) (2024)
Valeria Piattelli, Roberta Bartucci, Catharina Reker-Smit, Sander de Weerd, Christoffer Åberg, Victor Guryev, Diana Carolina Johanna Spierings, Anna Salvati
Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing. Nature nanotechnology 19 (7) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Anneke L Eerkens, Koen Brummel, Annegé Vledder, Sterre T Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M de Lange, Rie Klomp, David N Church, Arja Ter Elst, Rene Wardenaar, Diana Carolina Johanna Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K L Reyners, Marco de Bruyn, Hans W Nijman
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study. Nature communications 15 (1) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Colin R Gliech, Zhong Y Yeow, Daniel Tapias-Gomez, Yuchen Yang, Zhaoyu Huang, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Floris Foijer, Grace Chung, Nuria A Tamayo, Zahra Bahrami-Nejad, Patrick Collins, Thong T Nguyen, Andres Plata Stapper, Paul E Hughes, Marc Payton, Andrew Jon Holland
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition. The EMBO journal 43 (5) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports 25 (6) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
Valeria Piattelli, Roberta Bartucci, Catharina Reker-Smit, Sander de Weerd, Christoffer Åberg, Victor Guryev, Diana Carolina Johanna Spierings, Anna Salvati
Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing. Nature nanotechnology 19 (7) (2024)
Vincent Z Braun, Gerlinde Karbon, Fabian Schuler, Marina A Schapfl, Johannes G Weiss, Paul Y Petermann, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger
Extra centrosomes delay DNA damage-driven tumorigenesis. Science advances 10 (13) (2024)
Gerlinde Karbon, Fabian Schuler, Vincent Z Braun, Felix Eichin, Manuel Haschka, Mathias Drach, Rocío Sotillo, Stephan Geley, Diana Carolina Johanna Spierings, Andréa E Tijhuis, Floris Foijer, Andreas Villunger
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy. EMBO reports (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas-Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Coralie L Guerin, Paola Barbara Arimondo, Claire Francastel, Floris Foijer, Jorg Tost, Leonid A Mirny, Daniele Fachinetti
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. The Journal of cell biology 223 (4) (2024)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
Lavinia Spain, Alexander Coulton, Irene Lobon, Andrew Rowan, Desiree Schnidrig, Scott T C Shepherd, Benjamin Shum, Fiona Byrne, Maria Goicoechea, Elisa Piperni, Lewis Au, Kim Edmonds, Eleanor Carlyle, Nikki Hunter, Alexandra Renn, Christina Messiou, Peta Hughes, Jaime Nobbs, Floris Foijer, Hilda van den Bos, Rene Wardenaar, Diana Carolina Johanna Spierings, Charlotte Spencer, Andreas Michael Schmitt, Zayd Tippu, Karla Lingard, Lauren Grostate, Kema Peat, Kayleigh Kelly, Sarah Sarker, Sarah Vaughan, Mary Mangwende, Lauren Terry, Denise Kelly, Jennifer Biano, Aida Murra, Justine Korteweg, Charlotte Lewis, Molly OFlaherty, Anne-Laure Cattin, Max Emmerich, Camille L Gerard, Husayn Ahmed Pallikonda, Joanna Lynch, Robert Mason, Aljosja Rogiers, Hang Xu, Ariana Huebner, Nicholas McGranahan, Maise Al Bakir, Jun Murai, Cristina Naceur-Lombardelli, Elaine Borg, Miriam Mitchison, David Allan Moore, Mary Falzon, Ian Proctor, Gordon W H Stamp, Emma L Nye, Kate Young, Andrew J S Furness, Lisa M Pickering, Ruby Stewart, Ula Mahadeva, Anna C Green, James M G Larkin, Kevin Litchfield, Charles Swanton, Mariam Jamal-Hanjani, Samra Turajlic
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways. Cancer discovery (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
Timothy K Turkalo, Antonio Maffia, Johannes J Schabort, Samuel G Regalado, Mital Bhakta, Marco Blanchette, Diana Carolina Johanna Spierings, Peter M Lansdorp, Dirk Hockemeyer
A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells. Nature communications 14 (1) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
Fieke M Rosenberg, Rene Wardenaar, Angelique N Voorberg, Diana Carolina Johanna Spierings, Marie-Louise A Schuttelaar
Transcriptional differences between vesicular hand eczema and atopic dermatitis. Contact dermatitis (2023)
Timothy K Turkalo, Antonio Maffia, Johannes J Schabort, Samuel G Regalado, Mital Bhakta, Marco Blanchette, Diana Carolina Johanna Spierings, Peter M Lansdorp, Dirk Hockemeyer
A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells. Nature communications 14 (1) (2023)
Timothy K Turkalo, Antonio Maffia, Johannes J Schabort, Samuel G Regalado, Mital Bhakta, Marco Blanchette, Diana Carolina Johanna Spierings, Peter M Lansdorp, Dirk Hockemeyer
A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells. Nature communications 14 (1) (2023)
Timothy K Turkalo, Antonio Maffia, Johannes J Schabort, Samuel G Regalado, Mital Bhakta, Marco Blanchette, Diana Carolina Johanna Spierings, Peter M Lansdorp, Dirk Hockemeyer
A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells. Nature communications 14 (1) (2023)
Eleanor L Woodward, Minjun Yang, Larissa Helena Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Diana Carolina Johanna Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Nature communications 14 (1) (2023)
Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, Rene Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nicholas Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature communications 14 (1) (2023)
Laura Tovini, Sarah C Johnson, Molly A Guscott, Alexander M Andersen, Diana Carolina Johanna Spierings, Rene Wardenaar, Floris Foijer, Sarah E McClelland
Targeted assembly of ectopic kinetochores to induce chromosome-specific segmental aneuploidies. The EMBO journal (2023)
Timothy K Turkalo, Antonio Maffia, Johannes J Schabort, Samuel G Regalado, Mital Bhakta, Marco Blanchette, Diana Carolina Johanna Spierings, Peter M Lansdorp, Dirk Hockemeyer
A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells. Nature communications 14 (1) (2023)
Eleanor L Woodward, Minjun Yang, Larissa Helena Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Diana Carolina Johanna Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Nature communications 14 (1) (2023)
Eleanor L Woodward, Minjun Yang, Larissa Helena Moura-Castro, Hilda van den Bos, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Diana Carolina Johanna Spierings, Anders Castor, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Bertil Johansson, Floris Foijer, Kajsa Paulsson
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. Nature communications 14 (1) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine 16 (1) (2023)
William C Earnshaw, Carmen Ortega-Sabater, Namitha Thampi, Narcís Fernandez-Fuentes, Mercedes Guerrero Murillo, Alba Martínez-Moreno, Meritxell Vinyoles, Talía Velasco-Hernandez, Clara Bueno, Juan L Trincado, Isabel Granada, Diana Campos, Carles Giménez, Judith M Boer, Monique L den Boer, Gabriel F Calvo, Mireia Camós, Jose-Luis Fuster, Pablo Velasco, Paola Ballerini, Franco Locatelli, Charles G Mullighan, Diana Carolina Johanna Spierings, Floris Foijer, Victor M Pérez-García, Pablo Menéndez
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO molecular medicine (2023)
Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, Rene Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nicholas Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature communications 14 (1) (2023)
Lorenza Garribba, Giuseppina De Feudis, Valentino Martis, Martina Galli, Marie Dumont, Yonatan Eliezer, Rene Wardenaar, Marica Rosaria Ippolito, Divya Ramalingam Iyer, Andréa E Tijhuis, Diana Carolina Johanna Spierings, Michael Schubert, Silvia Taglietti, Chiara Soriani, Simon Gemble, Renata Basto, Nicholas Rhind, Floris Foijer, Uri Ben-David, Daniele Fachinetti, Ylli Doksani, Stefano Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature communications 14 (1) (2023)
Anne Margriet Heijink, Colin Stok, David Porubsky, Eleni Maria Manolika, Jurrian K de Kanter, Yannick P Kok, Marieke Everts, H Rudolf de Boer, Anastasia Audrey, Femke J Bakker, Elles Wierenga, Marcel Tijsterman, Victor Guryev, Diana Carolina Johanna Spierings, Puck Knipscheer, Ruben van Boxtel, Arnab Ray Chaudhuri, Peter M Lansdorp, Marcel A T M van Vugt
Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51. Nature communications 13 (1) (2022)
Simon Gemble, Rene Wardenaar, Kristina Keuper, Nishit Srivastava, Maddalena Nano, Anne-Sophie Macé, Andréa E Tijhuis, Sara Vanessa Bernhard, Diana Carolina Johanna Spierings, Anthony Simon, Oumou Goundiam, Helfrid Hochegger, Matthieu Piel, Floris Foijer, Zuzana Storchová, Renata Basto
Genetic instability from a single S phase after whole-genome duplication. Nature 604 (7904) (2022)
Christy Hong, Michael Schubert, Andréa E Tijhuis, Marta Requesens, Maurits Roorda, Anouk van den Brink, Lorena Andrade Ruiz, Petra L Bakker, Tineke van der Sluis, Wietske Pieters, Mengting Chen, Rene Wardenaar, Bert Van der Vegt, Diana Carolina Johanna Spierings, Marco de Bruyn, Marcel A T M van Vugt, Floris Foijer
cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers. Nature 607 (7918) (2022)
Irena Bočkaj, Tosca E I Martini, Marlinde J Smit, Inna Armandari, Bjorn Bakker, René Wardenaar, Tiny G J Meeuwsen-de Boer, Petra L Bakker, Diana Carolina Johanna Spierings, Eelco W Hoving, Victor Guryev, Floris Foijer, Sophia W M Bruggeman
Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum. International journal of molecular sciences 23 (17) (2022)
Joyce M Lubbers, Marta A Ważyńska, Nienke van Rooij, Arjan Kol, Hagma H Workel, Annechien Plat, Sterre T Paijens, Martijn R Vlaming, Diana Carolina Johanna Spierings, Philip H Elsinga, Edwin Bremer, Hans W Nijman, Marco de Bruyn
Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer. Cancers 14 (8) (2022)
Adriana Mañas, Kristina Aaltonen, Natalie Andersson, Karin Hansson, Aleksandra Adamska, Alexandra Seger, Hiroaki Yasui, Hilda van den Bos, Katarzyna Radke, Javanshir Esfandyari, Madhura Satish Bhave, Jenny Karlsson, Diana Carolina Johanna Spierings, Floris Foijer, David Gisselsson, Daniel Bexell
Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance. Science advances 8 (43) (2022)
Yael Cohen-Sharir, James M McFarland, Mai Abdusamad, Carolyn Marquis, Sara V Bernhard, Mariya Kazachkova, Helen Tang, Marica R Ippolito, Kathrin Laue, Johanna Zerbib, Heidi L H Malaby, Andrew Jones, Lisa-Marie Stautmeister, Irena Bockaj, René Wardenaar, Nicholas Lyons, Ankur K Nagaraja, Adam J Bass, Diana Carolina Johanna Spierings, Floris Foijer, Rameen Beroukhim, Stefano Santaguida, Todd R Golub, Jason Stumpff, Zuzana Storchová, Uri Ben-David
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition. Nature 590 (7846) (2021)
Vincent C T Hanlon, Carl-Adam Mattsson, Diana Carolina Johanna Spierings, Victor Guryev, Peter M Lansdorp
InvertypeR: Bayesian inversion genotyping with Strand-seq data. BMC genomics 22 (1) (2021)
Daniel Bronder, Anthony Tighe, Darawalee Wangsa, Dali Zong, Thomas J Meyer, René Wardenaar, Paul Minshall, Daniela Hirsch, Kerstin Heselmeyer-Haddad, Louisa Nelson, Diana Carolina Johanna Spierings, Joanne C McGrail, Maggie Cam, André Nussenzweig, Floris Foijer, Thomas Ried, Stephen S Taylor
TP53 loss initiates chromosomal instability in fallopian tube epithelial cells. Disease models & mechanisms 14 (11) (2021)
Klaske M Schukken, Yu-Chih Lin, Petra L Bakker, Michael Schubert, Stephanie F Preuß, Judith E Simon, Hilda van den Bos, Zuzana Storchová, Maria Colomé-Tatché, Holger Bastians, Diana Carolina Johanna Spierings, Floris Foijer
Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition. Life science alliance 3 (2) (2020)
Sjors Middelkamp, Helena T A van Tol, Diana Carolina Johanna Spierings, Sander Boymans, Victor Guryev, Bernard A J Roelen, Peter M Lansdorp, Edwin Cuppen, Ewart W Kuijk
Sperm DNA damage causes genomic instability in early embryonic development. Science advances 6 (16) (2020)
Hagma H Workel, Nienke van Rooij, Annechien Plat, Diana Carolina Johanna Spierings, Rudolf S N Fehrmann, Hans W Nijman, Marco de Bruyn
Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer. International journal of molecular sciences 21 (11) (2020)
Louisa Nelson, Anthony Tighe, Anya Golder, Samantha Littler, Bjorn Bakker, Daniella Moralli, Syed Murtuza Baker, Ian J Donaldson, Diana Carolina Johanna Spierings, René Wardenaar, Bethanie Neale, George J Burghel, Brett Winter-Roach, Richard Edmondson, Andrew R Clamp, Gordon C Jayson, Sudha Desai, Catherine M Green, Andrew Hayes, Floris Foijer, Robert D Morgan, Stephen S Taylor
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity. Nature communications 11 (1) (2020)
Natalie Andersson, Bjorn Bakker, Jenny Karlsson, Anders Valind, Linda Holmquist Mengelbier, Diana Carolina Johanna Spierings, Floris Foijer, David Gisselsson
Extensive Clonal Branching Shapes the Evolutionary History of High-Risk Pediatric Cancers. Cancer research 80 (7) (2020)
Menno Tamminga, Sanne de Wit, Caroline van de Wauwer, Hilda van den Bos, Joost F Swennenhuis, Theo J Klinkenberg, Thijo Jeroen N Hiltermann, Kiki C Andree, Diana Carolina Johanna Spierings, Peter M Lansdorp, Anke van den Berg, Hidde J Haisma, Leon W M M Terstappen, Harry J M Groen
Analysis of Released Circulating Tumor Cells During Surgery for Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (7) (2019)