Neil P King (N King, Neil King, N P King)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 65

Top Topics

Editorial Comment

Hepatitis C Virus

Binding Protein

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science (New York, N.Y.)

Nature structural & molecular biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Robbert J de Haas, Natalie Brunette, Alexander D Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, Julien S Baker, Neil P King
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proceedings of the National Academy of Sciences of the United States of America 121 (13) (2024)
Jimin Lee, Cameron Stewart, Alexandra Schaefer, Elizabeth M Leaf, Young-Jun Park, Daniel Asarnow, John M Powers, Catherine Treichel, Kaitlin R Sprouse, Davide Corti, Ralph S Baric, Neil P King, David J Veesler
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nature communications 15 (1) (2024)
Chloe S Adams, Hyojin Kim, Abigail E Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Ho Min Kim, Neil P King
De novo design of protein minibinder agonists of TLR3. bioRxiv : the preprint server for biology (2024)
Chloe S Adams, Hyojin Kim, Abigail E Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Ho Min Kim, Neil P King
De novo design of protein minibinder agonists of TLR3. bioRxiv : the preprint server for biology (2024)
Kristina R Edwards, Harman Malhi, Karina Schmidt, Amelia R Davis, Leah J Homad, Nikole L Warner, Crystal B Chhan, Samuel C Scharffenberger, Karen Gaffney, Troy C Hinkley, Nicole B Potchen, Jing Yang Wang, Jason Price, M Juliana McElrath, James Olson, Neil P King, Jennifer M Lund, Zoe Moodie, Jesse H Erasmus, Andrew T McGuire
A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge. NPJ vaccines 9 (1) (2024)
Ben S Ou, Julie Baillet, Maria V Filsinger Interrante, Julia Z Adamska, Xueting Zhou, Olivia M Saouaf, Jerry Yan, John H Klich, Carolyn K Jons, Emily L Meany, Adian S Valdez, Lauren Carter, Bali Pulendran, Neil P King, Eric A Appel
Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses. Science advances 10 (32) (2024)
Ben S Ou, Julie Baillet, Maria V Filsinger Interrante, Julia Z Adamska, Xueting Zhou, Olivia M Saouaf, Jerry Yan, John H Klich, Carolyn K Jons, Emily L Meany, Adian S Valdez, Lauren Carter, Bali Pulendran, Neil P King, Eric A Appel
Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses. Science advances 10 (32) (2024)
Robbert J de Haas, Natalie Brunette, Alexander D Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, Julien S Baker, Neil P King
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proceedings of the National Academy of Sciences of the United States of America 121 (13) (2024)
Jimin Lee, Cameron Stewart, Alexandra Schaefer, Elizabeth M Leaf, Young-Jun Park, Daniel Asarnow, John M Powers, Catherine Treichel, Kaitlin R Sprouse, Davide Corti, Ralph S Baric, Neil P King, David J Veesler
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nature communications 15 (1) (2024)
Kristina R Edwards, Harman Malhi, Karina Schmidt, Amelia R Davis, Leah J Homad, Nikole L Warner, Crystal B Chhan, Samuel C Scharffenberger, Karen Gaffney, Troy C Hinkley, Nicole B Potchen, Jing Yang Wang, Jason Price, M Juliana McElrath, James Olson, Neil P King, Jennifer M Lund, Zoe Moodie, Jesse H Erasmus, Andrew T McGuire
A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge. NPJ vaccines 9 (1) (2024)
Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Margaret Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua M Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P King, Julien S Baker
Computational design of non-porous pH-responsive antibody nanoparticles. Nature structural & molecular biology (2024)
Jimin Lee, Cameron Stewart, Alexandra Schaefer, Elizabeth M Leaf, Young-Jun Park, Daniel Asarnow, John M Powers, Catherine Treichel, Kaitlin R Sprouse, Davide Corti, Ralph S Baric, Neil P King, David J Veesler
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nature communications 15 (1) (2024)
Chloe S Adams, Hyojin Kim, Abigail E Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Ho Min Kim, Neil P King
De novo design of protein minibinder agonists of TLR3. bioRxiv : the preprint server for biology (2024)
Jimin Lee, Cameron Stewart, Alexandra Schaefer, Elizabeth M Leaf, Young-Jun Park, Daniel Asarnow, John M Powers, Catherine Treichel, Kaitlin R Sprouse, Davide Corti, Ralph S Baric, Neil P King, David J Veesler
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nature communications 15 (1) (2024)
Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Margaret Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua M Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P King, Julien S Baker
Computational design of non-porous pH-responsive antibody nanoparticles. Nature structural & molecular biology (2024)
Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Margaret Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua M Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P King, Julien S Baker
Computational design of non-porous pH-responsive antibody nanoparticles. Nature structural & molecular biology (2024)
Chloe S Adams, Hyojin Kim, Abigail E Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Ho Min Kim, Neil P King
De novo design of protein minibinder agonists of TLR3. bioRxiv : the preprint server for biology (2024)
Robbert J de Haas, Natalie Brunette, Alexander D Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, Julien S Baker, Neil P King
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proceedings of the National Academy of Sciences of the United States of America 121 (13) (2024)
Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, Will Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Margaret Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua M Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P King, Julien S Baker
Computational design of non-porous pH-responsive antibody nanoparticles. Nature structural & molecular biology (2024)
Robbert J de Haas, Natalie Brunette, Alexander D Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, Julien S Baker, Neil P King
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proceedings of the National Academy of Sciences of the United States of America 121 (13) (2024)
Robbert J de Haas, Natalie Brunette, Alexander D Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, Julien S Baker, Neil P King
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proceedings of the National Academy of Sciences of the United States of America 121 (13) (2024)
Kristina R Edwards, Harman Malhi, Karina Schmidt, Amelia R Davis, Leah J Homad, Nikole L Warner, Crystal B Chhan, Samuel C Scharffenberger, Karen Gaffney, Troy C Hinkley, Nicole B Potchen, Jing Yang Wang, Jason Price, M Juliana McElrath, James Olson, Neil P King, Jennifer M Lund, Zoe Moodie, Jesse H Erasmus, Andrew T McGuire
A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge. NPJ vaccines 9 (1) (2024)
Ben S Ou, Julie Baillet, Maria V Filsinger Interrante, Julia Z Adamska, Xueting Zhou, Olivia M Saouaf, Jerry Yan, John H Klich, Carolyn K Jons, Emily L Meany, Adian S Valdez, Lauren Carter, Bali Pulendran, Neil P King, Eric A Appel
Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses. Science advances 10 (32) (2024)
Robbert J de Haas, Roderick P Tas, Daniëlle van den Broek, Chuanbao Zheng, Hannah Nguyen, Alex Kang, Asim K Bera, Neil P King, Ilja Karina Voets, Renko de Vries
De novo designed ice-binding proteins from twist-constrained helices. Proceedings of the National Academy of Sciences of the United States of America 120 (27) (2023)
Robbert J de Haas, Roderick P Tas, Daniëlle van den Broek, Chuanbao Zheng, Hannah Nguyen, Alex Kang, Asim K Bera, Neil P King, Ilja Karina Voets, Renko de Vries
De novo designed ice-binding proteins from twist-constrained helices. Proceedings of the National Academy of Sciences of the United States of America 120 (27) (2023)
Robbert J de Haas, Natalie Brunette, Alex Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, Julien S Baker, Neil P King
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. bioRxiv : the preprint server for biology (2023)
Quinton M Dowling, Hannah E Volkman, Elizabeth E Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K Bera, Banumathi Sankaran, Max R Johnson, Matthew J Bick, Alex Kang, Daniel B Stetson, Neil P King
Computational design of constitutively active cGAS. Nature structural & molecular biology (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Quinton M Dowling, Hannah E Volkman, Elizabeth E Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K Bera, Banumathi Sankaran, Max R Johnson, Matthew J Bick, Alex Kang, Daniel B Stetson, Neil P King
Computational design of constitutively active cGAS. Nature structural & molecular biology 30 (1) (2023)
Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, William Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad H Abedi, Nicolas Goldbach, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua M Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P King, Julien S Baker
Computational design of non-porous, pH-responsive antibody nanoparticles. bioRxiv : the preprint server for biology (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Geoffrey B Hutchinson, Olubukola M Abiona, Cynthia T Ziwawo, Anne P Werner, Daniel Ellis, Yaroslav Tsybovsky, Sarah R Leist, Charis Palandjian, Ande West, Ethan J Fritch, Nianshuang Wang, Daniel Wrapp, Seyhan Boyoglu-Barnum, George Ueda, Julien S Baker, Masaru Kanekiyo, Jason S Mclellan, Ralph S Baric, Neil P King, Barney S Graham, Kizzmekia S Corbett-Helaire
Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera. Nature communications 14 (1) (2023)
Robbert J de Haas, Roderick P Tas, Daniëlle van den Broek, Chuanbao Zheng, Hannah Nguyen, Alex Kang, Asim K Bera, Neil P King, Ilja Karina Voets, Renko de Vries
De novo designed ice-binding proteins from twist-constrained helices. Proceedings of the National Academy of Sciences of the United States of America 120 (27) (2023)
Audrey Olshefsky, Halli Benasutti, Meilyn Sylvestre, Gabriel L Butterfield, Gabriel J Rocklin, Christian Richardson, Derrick R Hicks, Marc J Lajoie, Kefan Song, Elizabeth M Leaf, Catherine Treichel, Justin Decarreau, Sharon Ke, Gargi Kher, Lauren Carter, Jeffrey S Chamberlain, Julien S Baker, Neil P King, Suzie H Pun
In vivo selection of synthetic nucleocapsids for tissue targeting. Proceedings of the National Academy of Sciences of the United States of America 120 (46) (2023)
Jing Yang John Wang, Alena Khmelinskaia, William Sheffler, Marcos C Miranda, Aleksandar Antanasijevic, Andrew J Borst, Susana Vázquez Torres, Chelsea Shu, Yang Hsia, Una Nattermann, Daniel Ellis, Carl Walkey, Maggie Ahlrichs, Sidney Chan, Alex Kang, Hannah Nguyen, Claire Sydeman, Banumathi Sankaran, Mengyu Wu, Asim K Bera, Lauren Carter, Brooke Fiala, Michael Murphy, Julien S Baker, Andrew B Ward, Neil P King
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Jing Yang John Wang, Alena Khmelinskaia, William Sheffler, Marcos C Miranda, Aleksandar Antanasijevic, Andrew J Borst, Susana Vázquez Torres, Chelsea Shu, Yang Hsia, Una Nattermann, Daniel Ellis, Carl Walkey, Maggie Ahlrichs, Sidney Chan, Alex Kang, Hannah Nguyen, Claire Sydeman, Banumathi Sankaran, Mengyu Wu, Asim K Bera, Lauren Carter, Brooke Fiala, Michael Murphy, Julien S Baker, Andrew B Ward, Neil P King
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Jing Yang John Wang, Alena Khmelinskaia, William Sheffler, Marcos C Miranda, Aleksandar Antanasijevic, Andrew J Borst, Susana Vázquez Torres, Chelsea Shu, Yang Hsia, Una Nattermann, Daniel Ellis, Carl Walkey, Maggie Ahlrichs, Sidney Chan, Alex Kang, Hannah Nguyen, Claire Sydeman, Banumathi Sankaran, Mengyu Wu, Asim K Bera, Lauren Carter, Brooke Fiala, Michael Murphy, Julien S Baker, Andrew B Ward, Neil P King
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Yupeng Feng, Meng Yuan, John M Powers, Mengyun Hu, Jennifer E Munt, Prabhu S Arunachalam, Sarah R Leist, Lorenza Bellusci, Junghyun Kim, Kaitlin R Sprouse, Lily E Adams, Sumana Sundaramurthy, Xueyong Zhu, Lisa M Shirreff, Michael L Mallory, Trevor D Scobey, Alberto C Moreno, Derek T O'Hagan, Harry Kleanthous, François J Villinger, David J Veesler, Neil P King, Mehul S Suthar, Surender Khurana, Ralph S Baric, Ian A Wilson, Bali Pulendran
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Science translational medicine 15 (695) (2023)
Jing Yang John Wang, Alena Khmelinskaia, William Sheffler, Marcos C Miranda, Aleksandar Antanasijevic, Andrew J Borst, Susana Vázquez Torres, Chelsea Shu, Yang Hsia, Una Nattermann, Daniel Ellis, Carl Walkey, Maggie Ahlrichs, Sidney Chan, Alex Kang, Hannah Nguyen, Claire Sydeman, Banumathi Sankaran, Mengyu Wu, Asim K Bera, Lauren Carter, Brooke Fiala, Michael Murphy, Julien S Baker, Andrew B Ward, Neil P King
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Quinton M Dowling, Hannah E Volkman, Elizabeth E Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K Bera, Banumathi Sankaran, Max R Johnson, Matthew J Bick, Alex Kang, Daniel B Stetson, Neil P King
Computational design of constitutively active cGAS. Nature structural & molecular biology 30 (1) (2023)
Quinton M Dowling, Hannah E Volkman, Elizabeth E Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K Bera, Banumathi Sankaran, Max R Johnson, Matthew J Bick, Alex Kang, Daniel B Stetson, Neil P King
Computational design of constitutively active cGAS. Nature structural & molecular biology 30 (1) (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Yupeng Feng, Meng Yuan, John M Powers, Mengyun Hu, Jennifer E Munt, Prabhu S Arunachalam, Sarah R Leist, Lorenza Bellusci, Junghyun Kim, Kaitlin R Sprouse, Lily E Adams, Sumana Sundaramurthy, Xueyong Zhu, Lisa M Shirreff, Michael L Mallory, Trevor D Scobey, Alberto C Moreno, Derek T O'Hagan, Harry Kleanthous, François J Villinger, David J Veesler, Neil P King, Mehul S Suthar, Surender Khurana, Ralph S Baric, Ian A Wilson, Bali Pulendran
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Science translational medicine 15 (695) (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Quinton M Dowling, Hannah E Volkman, Elizabeth E Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K Bera, Banumathi Sankaran, Max R Johnson, Matthew J Bick, Alex Kang, Daniel B Stetson, Neil P King
Computational design of constitutively active cGAS. Nature structural & molecular biology 30 (1) (2023)
Isaac D Lutz, Shunzhi Wang, Christoffer H Norn, Alexis Courbet, Andrew J Borst, Yan Ting Zhao, Annie M Dosey, Longxing Cao, Jinwei Xu, Elizabeth M Leaf, Catherine Treichel, Patrisia Litvicov, Zhe Li, Alexander D Goodson, Paula Rivera-Sánchez, Ana-Maria Bratovianu, Minkyung Baek, Neil P King, Hannele Ruohola-Baker, Julien S Baker
Top-down design of protein architectures with reinforcement learning. Science (New York, N.Y.) 380 (6642) (2023)
Julien S Baker, Quinton Dowling, Young-Jun Park, Neil Gerstenmaier, Erin Yang, Adam Wargacki, Yang Hsia, Chelsea Fries, Rashmi Ravichandran, Carl Walkey, Anika Burrell, David J Veesler, Neil P King
Hierarchical design of pseudosymmetric protein nanoparticles. Research square (2023)
Erin C Yang, Robby Divine, Marcos C Miranda, Andrew J Borst, William Sheffler, Jason Z Zhang, Justin Decarreau, Amijai Saragovi, Mohamad H Abedi, Nicolas Goldbach, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua M Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P King, Julien S Baker
Computational design of non-porous, pH-responsive antibody nanoparticles. bioRxiv : the preprint server for biology (2023)
Prabhu S Arunachalam, Yupeng Feng, Usama Ashraf, Mengyun Hu, Alexandra C Walls, Venkata-Viswanadh Edara, Veronika I Zarnitsyna, Pyone Pyone Aye, Nadia Golden, Marcos C Miranda, Kristyn Moore Green, Breanna M Threeton, Nicholas J Maness, Brandon J Beddingfield, Rudolf P Bohm, Sarah E Scheuermann, Kelly Goff, Jason Dufour, Kasi Russell-Lodrigue, Elizabeth Kepl, Brooke Fiala, Samuel Wrenn, Rashmi Ravichandran, Daniel Ellis, Lauren Carter, Kenneth A Rogers, Lisa M Shirreff, Douglas E Ferrell, Nihar R Deb Adhikary, Jane Fontenot, Holly L Hammond, Matthew B Friemann, Alba Grifoni, Alessandro Sette, Derek T O'Hagan, Robbert G van der Most, Rino Rappuoli, François J Villinger, Harold Kleanthous, Jay Rappaport, Mehul S Suthar, David J Veesler, Taia T Wang, Neil P King, Bali Pulendran
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine. Science translational medicine 14 (658) (2022)
Alexis Courbet, Jesse M Hansen, Yang Hsia, Neville P Bethel, Young-Jun Park, Chunfu Xu, A Moyer, Scott E Boyken, George Ueda, Una Nattermann, Deepesh Nagarajan, Daniel Adriano Silva, William Sheffler, Joel Quispe, Ashley L Nord, Neil P King, Philip G Bradley, David J Veesler, Justin M Kollman, Julien S Baker
Computational design of mechanically coupled axle-rotor protein assemblies. Science (New York, N.Y.) 376 (6591) (2022)
Malika Hale, Jason Netland, Yu Chen, Christopher D Thouvenel, Katherine Nabel Smith, Lucille M Rich, Elizabeth R Vanderwall, Marcos C Miranda, Julie Eggenberger, Linhui Hao, Michael J Watson, Charles C Mundorff, Lauren B Rodda, Neil P King, Miklos M Guttman, Michael Gale, Jonathan Abraham, Jason S Debley, Marion Pepper, David J Rawlings
IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2. The Journal of experimental medicine 219 (9) (2022)
Kwinten Sliepen, Laura Radić, Joan Capella-Pujol, Yasunori Watanabe, Ian Zon, Ana Chumbe, Wen-Hsin Lee, Marlon de Gast, Jelle Koopsen, Sylvie Koekkoek, Iván Del Moral-Sánchez, Philip J M Brouwer, Rashmi Ravichandran, Gabriel Ozorowski, Neil P King, Andrew B Ward, Marit J VAN Gils, Max Crispin, Janke Schinkel, Rogier W Sanders
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate. Nature communications 13 (1) (2022)
Lilit Grigoryan, Audrey Lee, Alexandra C Walls, Lilin Lai, Benjamin Franco, Prabhu S Arunachalam, Yupeng Feng, Wei Luo, Abigail Vanderheiden, Katharine Floyd, Samuel Wrenn, Deleah Pettie, Marcos C Miranda, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Robert L Coffman, David Novack, Harry Kleanthous, Derek T O'Hagan, Robbert G van der Most, Jason S McLellan, Mehul Suthar, David Veesler, Neil P King, Bali Pulendran
Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice. NPJ vaccines 7 (1) (2022)
Geoffrey Hutchinson, Olubukola Abiona, Cynthia Ziwawo, Anne Werner, Daniel Ellis, Yaroslav Tsybovsky, Sarah Leist, Charis Palandjian, Ande West, Ethan Fritch, Niangshuang Wang, Daniel Wrapp, Seyhan Boyoglu-Barnum, George Ueda, Julien S Baker, Masaru Kanekiyo, Jason S Mclellan, Ralph S Baric, Neil P King, Barney Graham, Kizzmekia Corbett
Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups. Research square (2022)
Daniel Ellis, Julia Lederhofer, Oliver J Acton, Yaroslav Tsybovsky, Sally Kephart, Christina Yap, Rebecca A Gillespie, Adrian Creanga, Audrey Olshefsky, Tyler Stephens, Deleah Pettie, Michael Murphy, Claire Sydeman, Maggie Ahlrichs, Sidney Chan, Andrew J Borst, Young-Jun Park, Kelly K Lee, Barney S Graham, David J Veesler, Neil P King, Masaru Kanekiyo
Structure-based design of stabilized recombinant influenza neuraminidase tetramers. Nature communications 13 (1) (2022)
Justas Dauparas, David Baker, Nathaniel R Bennett, Hua Bai, Robert J Ragotte, Lukas F Milles, Basile I M Wicky, Alexis Courbet, Robbert J de Haas, Neville P Bethel, P J Y Leung, Timothy F Huddy, S Pellock, Doug K Tischer, F Chan, B Koepnick, Hannah Nguyen, Alex Kang, Banumathi Sankaran, Asim K Bera, Neil P King, Julien S Baker
Robust deep learning-based protein sequence design using ProteinMPNN. Science (New York, N.Y.) 378 (6615) (2022)
Prabhu S Arunachalam, Alexandra C Walls, Nadia Golden, Caroline Atyeo, Stephanie Fischinger, Chunfeng Li, Pyone Aye, Mary Jane Navarro, Lilin Lai, Venkata-Viswanadh Edara, Katharina Röeltgen, Kenneth Rogers, Lisa Shirreff, Douglas E Ferrell, Samuel Wrenn, Deleah Pettie, John C Kraft, Marcos C Miranda, Elizabeth Kepl, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Alexander G White, Meera Trisal, Ching-Lin Hsieh, Kasi E Russell-Lodrigue, Christopher Monjure, Jason Dufour, Skye Spencer, Lara Doyle-Meyers, Rudolph P Bohm, Nicholas J Maness, Chad J Roy, Jessica A Plante, Kenneth S Plante, Alex Lee Zhu, Matthew J Gorman, Sally A Shin, Xiaoying Shen, Jane Fontenot, Shakti Gupta, Derek T O'Hagan, Robbert Van Der Most, Rino Rappuoli, Robert L Coffman, David Novack, Jason S Mclellan, Shankar Subramaniam, David Montefiori, Scott D Boyd, Joanne L Flynn, Galit Alter, Francois Villinger, Harry Kleanthous, Jay Rappaport, Mehul S Suthar, Neil P King, David J Veesler, Bali Pulendran
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity. Nature 594 (7862) (2021)
Robby Divine, Ha V Dang, George Ueda, Jorge A Fallas, Ivan Vulovic, William Sheffler, Shally Saini, Yan Ting Zhao, Infencia Xavier Raj, Peter A Morawski, Madeleine F Jennewein, Leah J Homad, Yu-Hsin Wan, Marti R Tooley, Franziska Seeger, Ali Etemadi, Mitchell L Fahning, James Lazarovits, Alexander Roederer, Alexandra C Walls, Lance J Stewart, Mohammadali Mazloomi, Neil P King, Daniel J Campbell, Andrew T McGuire, Leonidas Stamatatos, Hannele Ruohola-Baker, Julie Mathieu, David J Veesler, Julien S Baker
Designed proteins assemble antibodies into modular nanocages. Science (New York, N.Y.) 372 (6537) (2021)
Aleksandar Antanasijevic, Leigh M Sewall, Christopher A Cottrell, Diane G Carnathan, Luis E Jimenez, Julia T Ngo, Jennifer B Silverman, Bettina Groschel, Erik Georgeson, Jinal Bhiman, Raiza Bastidas, Celia C LaBranche, Joel D Allen, Jeffrey Copps, Hailee R Perrett, Kimmo Rantalainen, Fabien Cannac, Yuhe R Yang, Alba Torrents de la Peña, Rebeca Froes Rocha, Zachary T Berndsen, Julien S Baker, Neil P King, Rogier W Sanders, John P Moore, Shane Crotty, Max Crispin, David C Montefiori, Dennis R Burton, William R Schief, Guido Silvestri, Andrew B Ward
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nature communications 12 (1) (2021)
Adam J Wargacki, Tobias P Wörner, Michiel van de Waterbeemd, Daniel Ellis, Albert J R Heck, Neil P King
Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials. Nature communications 12 (1) (2021)
Seyhan Boyoglu-Barnum, Daniel Ellis, Rebecca A Gillespie, Geoffrey B Hutchinson, Young-Jun Park, Syed M Moin, Oliver J Acton, Rashmi Ravichandran, Michael Murphy, Deleah Pettie, Nick Matheson, Lauren Carter, Adrian Creanga, Michael J Watson, Sally Kephart, Sila Ataca, John R Vaile, George Ueda, Michelle C Crank, Lance J Stewart, Kelly K Lee, Miklos Guttman, Julien S Baker, John R Mascola, David J Veesler, Barney S Graham, Neil P King, Masaru Kanekiyo
Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature 592 (7855) (2021)
Aleksandar Antanasijevic, George Ueda, Philip J M Brouwer, Jeffrey Copps, Deli Huang, Joel D Allen, Christopher A Cottrell, Anila Yasmeen, Leigh M Sewall, Ilja Bontjer, Thomas J Ketas, Hannah L Turner, Zachary T Berndsen, David C Montefiori, Per Johan Klasse, Max Crispin, David Nemazee, John P Moore, Rogier W Sanders, Neil P King, Julien S Baker, Andrew B Ward
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. PLoS pathogens 16 (8) (2020)
Scott E Boyken, Mark A Benhaim, Florian Busch, Mengxuan Jia, Matthew J Bick, Heejun Choi, Jason C Klima, Zibo Chen, Carl Walkey, Alexander Mileant, Aniruddha Sahasrabuddhe, Kathy Y Wei, Edgar A Hodge, Sarah Byron, Alfredo Quijano-Rubio, Banumathi Sankaran, Neil P King, Jennifer Lippincott-Schwartz, Vicki H Wysocki, Kelly K Lee, Julien S Baker
De novo design of tunable, pH-driven conformational changes. Science (New York, N.Y.) 364 (6441) (2019)