Alexander Marson (Alex Marson)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 69

Top Topics

Binding Protein

High Efficiency

Regulatory T Cells

Top Venues

Nature genetics

Nature biomedical engineering

This page only lists publications with an associated author ORCID identifier.

Publications

Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Harold Pimentel, Jacob W Freimer, Maya M Arce, Christian M Garrido, Alexander Marson, Jonathan K Pritchard
A model for accurate quantification of CRISPR effects in pooled FACS screens. bioRxiv : the preprint server for biology (2024)
Christopher R Chang, Vivasvan S Vykunta, Daniel B Goodman, Joseph J Muldoon, William A Nyberg, Chang Liu, Vincent Allain, Allison Rothrock, Charlotte H Wang, Alexander Marson, Brian R Shy, Justin Eyquem
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection. bioRxiv : the preprint server for biology (2024)
Christopher R Chang, Vivasvan S Vykunta, Daniel B Goodman, Joseph J Muldoon, William A Nyberg, Chang Liu, Vincent Allain, Allison Rothrock, Charlotte H Wang, Alexander Marson, Brian R Shy, Justin Eyquem
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection. bioRxiv : the preprint server for biology (2024)
Naomi M Pacalin, Zachary Steinhart, Quanming Shi, Julia A Belk, Dmytro Dorovskyi, Katerina Kraft, Kevin R Parker, Brian R Shy, Alexander Marson, Howard Y Chang
Bidirectional epigenetic editing reveals hierarchies in gene regulation. Nature biotechnology (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature (2024)
Harold Pimentel, Jacob W Freimer, Maya M Arce, Christian M Garrido, Alexander Marson, Jonathan K Pritchard
A model for accurate quantification of CRISPR effects in pooled FACS screens. bioRxiv : the preprint server for biology (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio (2024)
Cody T Mowery, Jacob W Freimer, Zeyu Chen, Salvador Casaní-Galdón, Jennifer M Umhoefer, Maya M Arce, Ketrin Gjoni, Bence Daniel, Katalin D Sandor, Benjamin G Gowen, Vinh Nguyen, Dimitre R Simeonov, Christian M Garrido, Gemma L Curie, Ralf Schmidt, Zachary Steinhart, Ansuman T Satpathy, Katherine S Pollard, Jacob E Corn, Bradley E Bernstein, Chun Jimmie Ye, Alexander Marson
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nature genetics 56 (6) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature (2024)
Cody T Mowery, Jacob W Freimer, Zeyu Chen, Salvador Casaní-Galdón, Jennifer M Umhoefer, Maya M Arce, Ketrin Gjoni, Bence Daniel, Katalin D Sandor, Benjamin G Gowen, Vinh Nguyen, Dimitre R Simeonov, Christian M Garrido, Gemma L Curie, Ralf Schmidt, Zachary Steinhart, Ansuman T Satpathy, Katherine S Pollard, Jacob E Corn, Bradley E Bernstein, Chun Jimmie Ye, Alexander Marson
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nature genetics 56 (6) (2024)
Cody T Mowery, Jacob W Freimer, Zeyu Chen, Salvador Casaní-Galdón, Jennifer M Umhoefer, Maya M Arce, Ketrin Gjoni, Bence Daniel, Katalin D Sandor, Benjamin G Gowen, Vinh Nguyen, Dimitre R Simeonov, Christian M Garrido, Gemma L Curie, Ralf Schmidt, Zachary Steinhart, Ansuman T Satpathy, Katherine S Pollard, Jacob E Corn, Bradley E Bernstein, Chun Jimmie Ye, Alexander Marson
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nature genetics (2024)
Cody T Mowery, Jacob W Freimer, Zeyu Chen, Salvador Casaní-Galdón, Jennifer M Umhoefer, Maya M Arce, Ketrin Gjoni, Bence Daniel, Katalin D Sandor, Benjamin G Gowen, Vinh Nguyen, Dimitre R Simeonov, Christian M Garrido, Gemma L Curie, Ralf Schmidt, Zachary Steinhart, Ansuman T Satpathy, Katherine S Pollard, Jacob E Corn, Bradley E Bernstein, Chun Jimmie Ye, Alexander Marson
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nature genetics 56 (6) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Samantha L Bucktrout, Nicholas E Banovich, Lisa H Butterfield, Cansu Cimen-Bozkus, Josephine R Giles, Zinaida Good, Daniel Goodman, Vanessa D Jonsson, Caleb A Lareau, Alexander Marson, Deena M Maurer, Paul V Munson, Mike Stubbington, Sarah Taylor, Abbey Cutchin
Publisher Correction: Advancing T cell-based cancer therapy with single-cell technologies. Nature medicine (2024)
Christopher R Chang, Vivasvan S Vykunta, Daniel B Goodman, Joseph J Muldoon, William A Nyberg, Chang Liu, Vincent Allain, Allison Rothrock, Charlotte H Wang, Alexander Marson, Brian R Shy, Justin Eyquem
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection. bioRxiv : the preprint server for biology (2024)
Cody T Mowery, Jacob W Freimer, Zeyu Chen, Salvador Casaní-Galdón, Jennifer M Umhoefer, Maya M Arce, Ketrin Gjoni, Bence Daniel, Katalin D Sandor, Benjamin G Gowen, Vinh Nguyen, Dimitre R Simeonov, Christian M Garrido, Gemma L Curie, Ralf Schmidt, Zachary Steinhart, Ansuman T Satpathy, Katherine S Pollard, Jacob E Corn, Bradley E Bernstein, Chun Jimmie Ye, Alexander Marson
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nature genetics 56 (6) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Cody T Mowery, Jacob W Freimer, Zeyu Chen, Salvador Casaní-Galdón, Jennifer M Umhoefer, Maya M Arce, Ketrin Gjoni, Bence Daniel, Katalin D Sandor, Benjamin G Gowen, Vinh Nguyen, Dimitre R Simeonov, Christian M Garrido, Gemma L Curie, Ralf Schmidt, Zachary Steinhart, Ansuman T Satpathy, Katherine S Pollard, Jacob E Corn, Bradley E Bernstein, Chun Jimmie Ye, Alexander Marson
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells. Nature genetics 56 (6) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Syed Bilal Ahmad Andrabi, Ubaid Ullah Kalim, Senthil Palani, Mohd Moin Khan, Meraj Hasan Khan, Jimmy Fagersund, Julius Orpana, Niklas Paulin, Kedar Batkulwar, Sini Junttila, Tanja Buchacher, Toni Grönroos, Lea Toikka, Tea Ammunet, Partho Sen, Matej Orešič, Venla Kumpulainen, Johanna E E Tuomisto, Rahul Sinha, Alexander Marson, Omid Rasool, Laura L Elo, Riitta Lahesmaa
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 + regulatory T cells by regulating IL2RA. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Christopher R Chang, Vivasvan S Vykunta, Daniel B Goodman, Joseph J Muldoon, William A Nyberg, Chang Liu, Vincent Allain, Allison Rothrock, Charlotte H Wang, Alexander Marson, Brian R Shy, Justin Eyquem
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection. bioRxiv : the preprint server for biology (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Syed Bilal Ahmad Andrabi, Ubaid Ullah Kalim, Senthil Palani, Mohd Moin Khan, Meraj Hasan Khan, Jimmy Fagersund, Julius Orpana, Niklas Paulin, Kedar Batkulwar, Sini Junttila, Tanja Buchacher, Toni Grönroos, Lea Toikka, Tea Ammunet, Partho Sen, Matej Orešič, Venla Kumpulainen, Johanna E E Tuomisto, Rahul Sinha, Alexander Marson, Omid Rasool, Laura L Elo, Riitta Lahesmaa
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 + regulatory T cells by regulating IL2RA. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Ujjwal Rathore, Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M Haas, Mehdi Bouhaddou, Danielle L Swaney, Erica Stevenson, Lorena Zuliani-Alvarez, Michael J McGregor, Autumn Turner-Groth, Charles Ochieng' Olwal, Yaw Bediako, Hannes Braberg, Margaret Soucheray, Melanie M Ott, Manon Eckhardt, Judd F Hultquist, Alexander Marson, Robyn M Kaake, Nevan J Krogan
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. mBio 15 (4) (2024)
Jun Yan, Paul Oyler-Castrillo, Purnima Ravisankar, Carl C Ward, Sébastien Levesque, Yangwode Jing, Danny Simpson, Anqi Zhao, Hui Li, Weihao Yan, Laine Goudy, Ralf Schmidt, Sabrina C Solley, Luke A Gilbert, Michelle M Chan, Daniel E Bauer, Alexander Marson, Lance R Parsons, Britt Adamson
Improving prime editing with an endogenous small RNA-binding protein. Nature 628 (8008) (2024)
Syed Bilal Ahmad Andrabi, Ubaid Ullah Kalim, Senthil Palani, Mohd Moin Khan, Meraj Hasan Khan, Jimmy Fagersund, Julius Orpana, Niklas Paulin, Kedar Batkulwar, Sini Junttila, Tanja Buchacher, Toni Grönroos, Lea Toikka, Tea Ammunet, Partho Sen, Matej Orešič, Venla Kumpulainen, Johanna E E Tuomisto, Rahul Sinha, Alexander Marson, Omid Rasool, Laura L Elo, Riitta Lahesmaa
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 + regulatory T cells by regulating IL2RA. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Syed Bilal Ahmad Andrabi, Ubaid Ullah Kalim, Senthil Palani, Mohd Moin Khan, Meraj Hasan Khan, Jimmy Fagersund, Julius Orpana, Niklas Paulin, Kedar Batkulwar, Sini Junttila, Tanja Buchacher, Toni Grönroos, Lea Toikka, Tea Ammunet, Partho Sen, Matej Orešič, Venla Kumpulainen, Johanna E E Tuomisto, Rahul Sinha, Alexander Marson, Omid Rasool, Laura L Elo, Riitta Lahesmaa
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 + regulatory T cells by regulating IL2RA. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Murad R Mamedov, Shane Vedova, Jacob W Freimer, Avinash Das Sahu, Amrita Ramesh, Maya M Arce, Angelo D Meringa, Mineto Ota, Peixin Amy Chen, Kristina Hanspers, Vinh Q Nguyen, Kirsten A Takeshima, Anne C Rios, Jonathan K Pritchard, Jürgen H E Kuball, Zsolt Sebestyen, Erin J Adams, Alexander Marson
CRISPR screens decode cancer cell pathways that trigger γδ T cell detection. Nature (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering 7 (5) (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering 7 (5) (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering 7 (5) (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering 7 (5) (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering (2023)
Ralf Schmidt, Carl C Ward, Rama Dajani, Zev Armour-Garb, Mineto Ota, Vincent Allain, Rosmely Hernandez, Madeline Layeghi, Galen Xing, Laine Goudy, Dmytro Dorovskyi, Charlotte Wang, Yan Yi Chen, Chun Jimmie Ye, Brian R Shy, Luke A Gilbert, Justin Eyquem, Jonathan K Pritchard, Stacie E Dodgson, Alexander Marson
Base-editing mutagenesis maps alleles to tune human T cell functions. Nature (2023)
Wan-Lin Lo, Miriam Kuhlmann, Gabrielle Rizzuto, H Atakan Ekiz, Elizabeth Motunrayo Kolawole, Monica P Revelo, Rakieb Andargachew, Zhongmei Li, Yuan-Li Tsai, Alexander Marson, Brian D Evavold, Dietmar Zehn, Arthur Weiss
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nature immunology (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering (2023)
Dana V Foss, Joseph J Muldoon, David N Nguyen, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nature biomedical engineering (2023)
Joseph Hiatt, Judd F Hultquist, Michael J McGregor, Mehdi Bouhaddou, Ryan T Leenay, Lacy M Simons, Janet M Young, Paige Haas, Theodore L Roth, Victoria R Tobin, Jason A Wojcechowskyj, Jonathan M Woo, Ujjwal Rathore, Devin A Cavero, Eric Shifrut, Thong T Nguyen, Kelsey M Haas, Harmit S Malik, Jennifer A Doudna, Andrew P May, Alexander Marson, Nevan J Krogan
A functional map of HIV-host interactions in primary human T cells. Nature communications 13 (1) (2022)
Brian R Shy, Vivasvan S Vykunta, Alvin Ha, Alexis Talbot, Theodore L Roth, David N Nguyen, Wolfgang G Pfeifer, Yan Yi Chen, Franziska Blaeschke, Eric Shifrut, Shane Vedova, Murad R Mamedov, Jing-Yi Jing Chung, Hong Li, Ruby Yu, David Wu, Jeffrey Wolf, Thomas G Martin, Carlos E Castro, Lumeng Ye, Jonathan H Esensten, Justin Eyquem, Alexander Marson
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails. Nature biotechnology (2022)
Jacob W Freimer, Oren Shaked, Sahin Naqvi, Nicholas A Sinnott-Armstrong, Arwa Kathiria, Christian M Garrido, Amy F Chen, Jessica T Cortez, William J Greenleaf, Jonathan K Pritchard, Alexander Marson
Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks. Nature genetics 54 (8) (2022)
Dan Liu, Lihui Duan, Lauren B Rodda, Erick Lu, Ying Xu, Jinping An, Longhui Qiu, Fengchun Liu, Mark R Looney, Zhiyong Yang, Christopher D C Allen, Zhongmei Li, Alexander Marson, Jason G Cyster
CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells. Science (New York, N.Y.) 375 (6581) (2022)
Antonia E Gallman, Finn D Wolfreys, David N Nguyen, Moriah Sandy, Ying Xu, Jinping An, Zhongmei Li, Alexander Marson, Erick Lu, Jason G Cyster
Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of S-geranylgeranyl-l-glutathione. Science immunology 6 (60) (2022)
Ralf Schmidt, Zachary Steinhart, Madeline Layeghi, Jacob W Freimer, Raymund Bueno, Vinh Q Nguyen, Franziska Blaeschke, Chun Jimmie Ye, Alexander Marson
CRISPR activation and interference screens decode stimulation responses in primary human T cells. Science (New York, N.Y.) 375 (6580) (2022)
Samantha L Bucktrout, Nicholas E Banovich, Lisa H Butterfield, Cansu Cimen-Bozkus, Josephine R Giles, Zinaida Good, Daniel Goodman, Vanessa D Jonsson, Caleb A Lareau, Alexander Marson, Denna M Maurer, Paul V Munson, Mike Stubbington, Sarah Taylor, Abbey Cutchin
Advancing T cell-based cancer therapy with single-cell technologies. Nature medicine 28 (9) (2022)
Julia Carnevale, Eric Shifrut, Nupura Kale, William A Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P Bapat, Morgan E Diolati, Patrick C O'Leary, Shane Vedova, Julia A Belk, Bence Daniel, Theodore L Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maelys Born-Bony, Bindu Hegde, Scott C Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson
RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609 (7925) (2022)
Jun Hyung Sin, Sujit Kashyap, Dante Acenas, Jessica T Cortez, James C Lee, Alexander Marson, Mehrdad Matloubian, Michael R Waterfield
ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8 + T Cell Effector and Memory Responses. Journal of immunology (Baltimore, Md. : 1950) 208 (5) (2022)
Sagar P Bapat, Caroline Whitty, Cody T Mowery, Yuqiong Liang, Arum Yoo, Zewen Jiang, Michael C Peters, Ling-Juan Zhang, Ian Vogel, Carmen Zhou, Vinh Q Nguyen, Zhongmei Li, Christina Chang, Wandi S Zhu, Annette T Hastie, Helen He, Xin Ren, Wenli Qiu, Sarah G Gayer, Chang Liu, Eun Jung Choi, Marlys S Fassett, Jarish N Cohen, Jamie L Sturgill, Laura E Crotty Alexander, Jae Myoung Suh, Christopher Liddle, Annette R Atkins, Ruth T Yu, Michael Downes, Sihao Liu, Barbara S Nikolajczyk, In-Kyu Lee, Emma Guttman-Yassky, Karl Mark Ansel, Prescott G Woodruff, John V Fahy, Dean Sheppard, Richard L Gallo, Chun Jimmie Ye, Ronald M Evans, Ye Zheng, Alexander Marson
Obesity alters pathology and treatment response in inflammatory disease. Nature 604 (7905) (2022)
Daniel B Goodman, Camillia S Azimi, Kendall Kearns, Alexis Talbot, Kiavash Garakani, Julie M Garcia, Nisarg A Patel, Byungjin Hwang, David S Lee, Minhee Park, Vivasvan S Vykunta, Brian R Shy, Chun Jimmie Ye, Justin Eyquem, Alexander Marson, Jeffrey A Bluestone, Kole T Roybal
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies. Science translational medicine 14 (670) (2022)
Youjin Lee, Derek Bogdanoff, Yutong Wang, George C Hartoularos, Jonathan M Woo, Cody T Mowery, Hunter M Nisonoff, David S Lee, Yang Sun, James C Lee, Sadaf Mehdizadeh, Joshua Cantlon, Eric Shifrut, David N Nguyen, Theodore L Roth, Yun S Song, Alexander Marson, Eric D Chow, Chun Jimmie Ye
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment. Science advances 7 (17) (2021)
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