Dirk Grimm

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Hepatitis B Virus

Top Venues

Nature communications

Communications biology

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jannik T Wagner, Sandra M Müller-Schmucker, Wenjun Wang, Philipp Arnold, Nadja Uhlig, Leila Issmail, Valentina Eberlein, Dominik Damm, Kaveh Roshanbinfar, Armin Ensser, Friederike Oltmanns, Antonia Sophia Peter, Vladimir Temchura, Silke Schrödel, Felix B Engel, Christian Thirion, Thomas Grunwald, Dana L E Vergoossen, Dirk Grimm, Klaus Überla
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2. Communications biology 7 (1) (2024)
Hichem Tasfaout, Christine L Halbert, Timothy S McMillen, James M Allen, Theodore R Reyes, Galina V Flint, Dirk Grimm, Stephen D Hauschka, Michael Regnier, Jeffrey S Chamberlain
Split intein-mediated protein trans-splicing to express large dystrophins. Nature (2024)
Huanting Chi, Bingqian Qu, Angga Prawira, Talisa Richardt, Lars Maurer, Jungen Hu, Rebecca M Fu, Florian A Lempp, Zhenfeng Zhang, Dirk Grimm, Xianfang Wu, Stephan Urban, Viet Loan Dao Thi
An hepatitis B and D virus infection model using human pluripotent stem cell-derived hepatocytes. EMBO reports (2024)
Jannik T Wagner, Sandra M Müller-Schmucker, Wenjun Wang, Philipp Arnold, Nadja Uhlig, Leila Issmail, Valentina Eberlein, Dominik Damm, Kaveh Roshanbinfar, Armin Ensser, Friederike Oltmanns, Antonia Sophia Peter, Vladimir Temchura, Silke Schrödel, Felix B Engel, Christian Thirion, Thomas Grunwald, Dana L E Vergoossen, Dirk Grimm, Klaus Überla
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2. Communications biology 7 (1) (2024)
Hichem Tasfaout, Christine L Halbert, Timothy S McMillen, James M Allen, Theodore R Reyes, Galina V Flint, Dirk Grimm, Stephen D Hauschka, Michael Regnier, Jeffrey S Chamberlain
Split intein-mediated protein trans-splicing to express large dystrophins. Nature 632 (8023) (2024)
Jannik T Wagner, Sandra M Müller-Schmucker, Wenjun Wang, Philipp Arnold, Nadja Uhlig, Leila Issmail, Valentina Eberlein, Dominik Damm, Kaveh Roshanbinfar, Armin Ensser, Friederike Oltmanns, Antonia Sophia Peter, Vladimir Temchura, Silke Schrödel, Felix B Engel, Christian Thirion, Thomas Grunwald, Dana L E Vergoossen, Dirk Grimm, Klaus Überla
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2. Communications biology 7 (1) (2024)
Hichem Tasfaout, Christine L Halbert, Timothy S McMillen, James M Allen, Theodore R Reyes, Galina V Flint, Dirk Grimm, Stephen D Hauschka, Michael Regnier, Jeffrey S Chamberlain
Split intein-mediated protein trans-splicing to express large dystrophins. Nature 632 (8023) (2024)
Hichem Tasfaout, Christine L Halbert, Timothy S McMillen, James M Allen, Theodore R Reyes, Galina V Flint, Dirk Grimm, Stephen D Hauschka, Michael Regnier, Jeffrey S Chamberlain
Split intein-mediated protein trans-splicing to express large dystrophins. Nature 632 (8023) (2024)
Hichem Tasfaout, Christine L Halbert, Timothy S McMillen, James M Allen, Theodore R Reyes, Galina V Flint, Dirk Grimm, Stephen D Hauschka, Michael Regnier, Jeffrey S Chamberlain
Split intein-mediated protein trans-splicing to express large dystrophins. Nature 632 (8023) (2024)
Jannik T Wagner, Sandra M Müller-Schmucker, Wenjun Wang, Philipp Arnold, Nadja Uhlig, Leila Issmail, Valentina Eberlein, Dominik Damm, Kaveh Roshanbinfar, Armin Ensser, Friederike Oltmanns, Antonia Sophia Peter, Vladimir Temchura, Silke Schrödel, Felix B Engel, Christian Thirion, Thomas Grunwald, Dana L E Vergoossen, Dirk Grimm, Klaus Überla
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2. Communications biology 7 (1) (2024)
Hichem Tasfaout, Christine L Halbert, Timothy S McMillen, James M Allen, Theodore R Reyes, Galina V Flint, Dirk Grimm, Stephen D Hauschka, Michael Regnier, Jeffrey S Chamberlain
Split intein-mediated protein trans-splicing to express large dystrophins. Nature (2024)
Markus Grosch, Laura Schraft, Adrian Chan, Leonie Küchenhoff, Kleopatra Rapti, Anne-Maud Ferreira, Julia Kornienko, Shengdi Li, Michael H Radke, Chiara Krämer, Sandra Clauder-Münster, Emerald Perlas, Johannes Backs, Michael Gotthardt, Christoph Dieterich, Maarten M G van den Hoogenhof, Dirk Grimm, Lars M Steinmetz
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy. Nature communications 14 (1) (2023)
Marco Thürkauf, Shuo Lin, Filippo Oliveri, Dirk Grimm, Randall J Platt, Markus A Rüegg
Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9. Nature communications 14 (1) (2023)
Nevena Stajković, Yuanyuan Liu, Aleksandra Arsić, Ning Meng, Hang Lyu, Nan Zhang, Dirk Grimm, Holger Lerche, Ivana Nikić-Spiegel
Direct fluorescent labeling of NF186 and NaV1.6 in living primary neurons using bioorthogonal click chemistry. Journal of cell science (2023)
Lea Jessica Flitsch, Kathleen Boerner, Christian Stüllein, Simon Ziegler, Vera Sonntag-Buck, Ellen Wiedtke, Vesselina Semkova, Si Wah Christina Au Yeung, Julia Schlee, Mohamad Hajo, Mona Mathews, Beatrice Stefanie Ludwig, Susanne Kossatz, Horst Kessler, Dirk Grimm, Oliver Brüstle
Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening. Scientific reports 12 (1) (2022)
Elena Melendez, Dafni Chondronasiou, Lluc Mosteiro, Jaime Martínez de Villarreal, Marcos Fernández-Alfara, Cian J Lynch, Dirk Grimm, Francisco X Real, José Alcamí, Núria Climent, Federico Pietrocola, Manuel Serrano
Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Development (Cambridge, England) 149 (8) (2022)
Jihad El Andari, Edith Renaud-Gabardos, Warut Tulalamba, Jonas Weinmann, Louise Mangin, Quang Hong Pham, Susanne Hille, Antonette Bennett, Esther Attebi, Emanuele Bourges, Christian Leborgne, Nicolas Guerchet, Julia Fakhiri, Chiara Krämer, Ellen Wiedtke, Robert McKenna, Laurence Guianvarc'h, Magali Toueille, Giuseppe Ronzitti, Matthias Hebben, Federico Mingozzi, Thierry VandenDriessche, Mavis Agbandje-McKenna, Oliver J Müller, Marinee K Chuah, Ana Buj-Bello, Dirk Grimm
Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders. Science advances 8 (38) (2022)
Jonas Becker, Julia Fakhiri, Dirk Grimm
Fantastic AAV Gene Therapy Vectors and How to Find Them-Random Diversification, Rational Design and Machine Learning. Pathogens (Basel, Switzerland) 11 (7) (2022)
Leonard Ernst, Benedikt Steinfeld, Uladzimir Barayeu, Thomas Klintzsch, Markus Kurth, Dirk Grimm, Tobias P Dick, Johannes G Rebelein, Ilka B Bischofs, Frank Keppler
Methane formation driven by reactive oxygen species across all living organisms. Nature 603 (7901) (2022)
Alice Rovai, BoMee Chung, Qingluan Hu, Sebastian Hook, Qinggong Yuan, Tibor Kempf, Florian Schmidt, Dirk Grimm, Steven R Talbot, Lars Steinbrück, Jasper Götting, Jens Bohne, Simon A Krooss, Michael Ott
In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Nature communications 13 (1) (2022)
Felix Bubeck, Dirk Grimm
'Hit and run' therapy averts macular degeneration. Nature biomedical engineering 5 (2) (2021)
Chady H Hakim, Sandeep R P Kumar, Dennis O Pérez-López, Nalinda B Wasala, Dong Zhang, Yongping Yue, James Teixeira, Xiufang Pan, Keqing Zhang, Emily D Million, Christopher E Nelson, Samantha Metzger, Jin Han, Jacqueline A Louderman, Florian Schmidt, Feng Feng, Dirk Grimm, Bruce F Smith, Gang Yao, N Nora Yang, Charles A Gersbach, Shi-Jie Chen, Roland W Herzog, Dongsheng Duan
Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models. Nature communications 12 (1) (2021)
Jonas Weinmann, Sabrina Weis, Josefine Sippel, Warut Tulalamba, Anca Remes, Jihad El Andari, Anne-Kathrin Herrmann, Quang H Pham, Christopher Borowski, Susanne Hille, Tanja Schönberger, Norbert Frey, Martin Lenter, Thierry VandenDriessche, Oliver J Müller, Marinee K Chuah, Thorsten Lamla, Dirk Grimm
Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants. Nature communications 11 (1) (2020)
Jan Mathony, Zander Harteveld, Carolin Schmelas, Julius Upmeier Zu Belzen, Sabine Aschenbrenner, Wei Sun, Mareike D Hoffmann, Christina Stengl, Andreas Scheck, Sandrine Georgeon, Stéphane Rosset, Yanli Wang, Dirk Grimm, Roland Eils, Bruno E Correia, Dominik Niopek
Computational design of anti-CRISPR proteins with improved inhibition potency. Nature chemical biology 16 (7) (2020)
Jihad El Andari, Dirk Grimm
Production, Processing, and Characterization of Synthetic AAV Gene Therapy Vectors. Biotechnology journal 16 (1) (2020)
Anne-Kathrin Herrmann, Christian Bender, Eike Kienle, Stefanie Grosse, Jihad El Andari, Julia Botta, Nina Schürmann, Ellen Wiedtke, Dominik Niopek, Dirk Grimm
A Robust and All-Inclusive Pipeline for Shuffling of Adeno-Associated Viruses. ACS synthetic biology 8 (1) (2019)
Warut Tulalamba, Jonas Weinmann, Quang Hong Pham, Jihad El Andari, Thierry VandenDriessche, Marinee K Chuah, Dirk Grimm
Distinct transduction of muscle tissue in mice after systemic delivery of AAVpo1 vectors. Gene therapy 27 (3-4) (2019)
Leonela Amoasii, Chengzu Long, Hui Li, Alex A Mireault, John M Shelton, Efrain Sanchez-Ortiz, John R McAnally, Samadrita Bhattacharyya, Florian Schmidt, Dirk Grimm, Stephen D Hauschka, Rhonda Bassel-Duby, Eric N Olson
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. Science translational medicine 9 (418) (2018)
Jonas Weinmann, Dirk Grimm
Next-generation AAV vectors for clinical use: an ever-accelerating race. Virus genes 53 (5) (2017)
Thomas Michler, Stefanie Große, Stefan Mockenhaupt, Natalie Röder, Ferdinand Stückler, Bettina Knapp, Chunkyu Ko, Mathias Heikenwalder, Ulrike Protzer, Dirk Grimm
Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA. EMBO molecular medicine 8 (9) (2016)