Jeremy Adam Ryan (Jeremy Ryan, Jeremy A Ryan)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Venues

Blood advances

Blood cancer discovery

eLife

Proceedings of the National Academy of Sciences of the United States of America

Dana Farber Cancer Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dana Farber Cancer Institute

United States

Staff Scientist :: Medical Oncology

Publications

Elyse A Olesinski, Karanpreet Singh Bhatia, Chuqi Wang, Marissa S Pioso, Xiao Xian Lin, Ahmed M Mamdouh, Shu Xuan Ng, Vedant Sandhu, Shaista Shabbir Jasdanwala, Binyam Yilma, Stephan Bohl, Jeremy Adam Ryan, Disha Malani, Marlise R Luskin, Olli Kallioniemi, Kimmo Porkka, Sophia Adamia, Wee-Joo Chng, Motomi Osato, David M Weinstock, Jacqueline S Garcia, Anthony G Letai, Shruti Bhatt
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts. Blood cancer discovery (2024)
Jacqueline S Garcia, Haesook T Kim, H Moses Murdock, Michela Ansuinelli, Jennifer Brock, Corey S Cutler, Mahasweta Gooptu, Vincent T Ho, John Koreth, Sarah Nikiforow, Rizwan Romee, Roman Shapiro, Daniel J DeAngelo, Richard M Stone, Denbaa Bat-Erdene, Jeremy Adam Ryan, Manuel E Contreras, Geoffrey G Fell, Anthony Letai, Jerome Ritz, R Coleman Lindsley, Robert J Soiffer, Joseph H Antin
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML. Blood advances 8 (4) (2024)
Jacqueline S Garcia, Haesook T Kim, H Moses Murdock, Michela Ansuinelli, Jennifer Brock, Corey S Cutler, Mahasweta Gooptu, Vincent T Ho, John Koreth, Sarah Nikiforow, Rizwan Romee, Roman Shapiro, Daniel J DeAngelo, Richard M Stone, Denbaa Bat-Erdene, Jeremy Adam Ryan, Manuel E Contreras, Geoffrey G Fell, Anthony Letai, Jerome Ritz, R Coleman Lindsley, Robert J Soiffer, Joseph H Antin
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML. Blood advances 8 (4) (2024)
Elyse A Olesinski, Karanpreet Singh Bhatia, Chuqi Wang, Marissa S Pioso, Xiao Xian Lin, Ahmed M Mamdouh, Shu Xuan Ng, Vedant Sandhu, Shaista Shabbir Jasdanwala, Binyam Yilma, Stephan Bohl, Jeremy Adam Ryan, Disha Malani, Marlise R Luskin, Olli Kallioniemi, Kimmo Porkka, Sophia Adamia, Wee-Joo Chng, Motomi Osato, David M Weinstock, Jacqueline S Garcia, Anthony G Letai, Shruti Bhatt
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts. Blood cancer discovery 5 (3) (2024)
Elyse A Olesinski, Karanpreet Singh Bhatia, Chuqi Wang, Marissa S Pioso, Xiao Xian Lin, Ahmed M Mamdouh, Shu Xuan Ng, Vedant Sandhu, Shaista Shabbir Jasdanwala, Binyam Yilma, Stephan Bohl, Jeremy Adam Ryan, Disha Malani, Marlise R Luskin, Olli Kallioniemi, Kimmo Porkka, Sophia Adamia, Wee-Joo Chng, Motomi Osato, David M Weinstock, Jacqueline S Garcia, Anthony G Letai, Shruti Bhatt
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts. Blood cancer discovery 5 (3) (2024)
Jacqueline S Garcia, Haesook T Kim, H Moses Murdock, Michela Ansuinelli, Jennifer Brock, Corey S Cutler, Mahasweta Gooptu, Vincent T Ho, John Koreth, Sarah Nikiforow, Rizwan Romee, Roman Shapiro, Daniel J DeAngelo, Richard M Stone, Denbaa Bat-Erdene, Jeremy Adam Ryan, Manuel E Contreras, Geoffrey G Fell, Anthony Letai, Jerome Ritz, R Coleman Lindsley, Robert J Soiffer, Joseph H Antin
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML. Blood advances 8 (4) (2024)
Elyse A Olesinski, Karanpreet Singh Bhatia, Chuqi Wang, Marissa S Pioso, Xiao Xian Lin, Ahmed M Mamdouh, Shu Xuan Ng, Vedant Sandhu, Shaista Shabbir Jasdanwala, Binyam Yilma, Stephan Bohl, Jeremy Adam Ryan, Disha Malani, Marlise R Luskin, Olli Kallioniemi, Kimmo Porkka, Sophia Adamia, Wee-Joo Chng, Motomi Osato, David M Weinstock, Jacqueline S Garcia, Anthony G Letai, Shruti Bhatt
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts. Blood cancer discovery 5 (3) (2024)
Elyse A Olesinski, Karanpreet Singh Bhatia, Chuqi Wang, Marissa S Pioso, Xiao Xian Lin, Ahmed M Mamdouh, Shu Xuan Ng, Vedant Sandhu, Shaista Shabbir Jasdanwala, Binyam Yilma, Stephan Bohl, Jeremy Adam Ryan, Disha Malani, Marlise R Luskin, Olli Kallioniemi, Kimmo Porkka, Sophia Adamia, Wee-Joo Chng, Motomi Osato, David M Weinstock, Jacqueline S Garcia, Anthony G Letai, Shruti Bhatt
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts. Blood cancer discovery 5 (3) (2024)
Jacqueline S Garcia, Haesook T Kim, H Moses Murdock, Michela Ansuinelli, Jennifer Brock, Corey S Cutler, Mahasweta Gooptu, Vincent T Ho, John Koreth, Sarah Nikiforow, Rizwan Romee, Roman M Shapiro, Daniel J DeAngelo, Richard M Stone, Denbaa Bat-Erdene, Jeremy Adam Ryan, Manuel E Contreras, Geoffrey G Fell, Anthony Letai, Jerome Ritz, R Coleman Lindsley, Robert J Soiffer, Joseph H Antin
Prophylactic maintenance with venetoclax/azacitidine after reduced intensity conditioning allo-transplant for high risk MDS and AML. Blood advances (2024)
Jacqueline S Garcia, Haesook T Kim, H Moses Murdock, Michela Ansuinelli, Jennifer Brock, Corey S Cutler, Mahasweta Gooptu, Vincent T Ho, John Koreth, Sarah Nikiforow, Rizwan Romee, Roman Shapiro, Daniel J DeAngelo, Richard M Stone, Denbaa Bat-Erdene, Jeremy Adam Ryan, Manuel E Contreras, Geoffrey G Fell, Anthony Letai, Jerome Ritz, R Coleman Lindsley, Robert J Soiffer, Joseph H Antin
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML. Blood advances 8 (4) (2024)
Emmalyn Lecky, Atreyi Mukherji, Rebecca German, Gabriella Antonellis, Jia-Ren Lin, Michael Yorsz, Kelley E McQueeney, Jeremy Adam Ryan, Kimmie Ng, Ewa Sicinska, Peter Karl Sorger, Anthony G Letai, Patrick D Bhola
Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells. Science advances 9 (25) (2023)
Alexandra L Pourzia, Michael L Olson, Stefanie R Bailey, Angela C Boroughs, Aditi Aryal, Jeremy Adam Ryan, Marcela V Maus, Anthony G Letai
Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells. Cell death & disease 14 (4) (2023)
Jacob M Winter, Heidi L Fresenius, Corey N Cunningham, Peng Wei, Heather R Keys, Jordan A Berg, Alex J Bott, Tarun Yadav, Jeremy Adam Ryan, Deepika Sirohi, Sheryl R Tripp, Paige Barta, Neeraj Agarwal, Anthony Letai, David M Sabatini, Matthew L Wohlever, Jared Rutter
Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction. eLife 11 (2022)
Ruth Flümann, Tim Rehkämper, Pascal Nieper, Pauline Pfeiffer, Alessandra Holzem, Sebastian Klein, Sanil Bhatia, Moritz Kochanek, Ilmars Kisis, Benedikt W Pelzer, Heinz Ahlert, Julia Hauer, Alexandra da Palma Guerreiro, Jeremy Adam Ryan, Maurice Reimann, Arina Riabinska, Janica Wiederstein, Marcus Krüger, Martina Deckert, Janine Altmüller, Andreas R Klatt, Lukas P Frenzel, Laura Pasqualucci, Wendy Béguelin, Ari M Melnick, Sandrine Sander, Manuel Montesinos-Rongen, Anna Brunn, Philipp Lohneis, Reinhard Büttner, Hamid Kashkar, Arndt Borkhardt, Anthony Letai, Thorsten Persigehl, Martin Peifer, Clemens A Schmitt, Hans Christian Reinhardt, Gero Knittel
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood cancer discovery 2 (1) (2022)
Jing Deng, Aneel Paulus, Douglas D Fang, Alak Manna, Guangfeng Wang, Hengbang Wang, Saijie Zhu, Jianyong Chen, Ping Min, Yan Yin, Navnita Dutta, Nabanita Halder, Gina Ciccio, John A Copland Iii, James L Miller, Bing Han, Longchuan Bai, Liu Liu, Mi Wang, Donna McEachern, Sally Przybranowski, Chao-Yie Yang, Jeanne A Stuckey, De-Pei Wu, Caixia Li, Jeremy Adam Ryan, Anthony G Letai, Sikandar Ailawadhi, Dajun Yang, Shaomeng Wang, Asher A Chanan-Khan, Yifan Zhai
Lisaftoclax (APG-2575) is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N Konoplev, Shannon R Sweeney, Jeremy Adam Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata Lokesh Battula, Yingchang Mi, Jing Wang, Courtney D DiNardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony G Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. Signal transduction and targeted therapy 7 (1) (2022)
Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N Konoplev, Shannon R Sweeney, Jeremy Adam Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata Lokesh Battula, Yingchang Mi, Jing Wang, Courtney D DiNardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony G Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. Signal transduction and targeted therapy 7 (1) (2022)
Jacqueline S Garcia, Haesook T Kim, H Moses Murdock, Corey S Cutler, Jennifer Brock, Mahasweta Gooptu, Vincent T Ho, John Koreth, Sarah Nikiforow, Rizwan Romee, Roman M Shapiro, Fiona Loschi, Jeremy Adam Ryan, Geoffrey Fell, Hannah Q Karp, Jennifer A Woyach, Annette S Kim, Danielle Sinead Potter, Thelma Mashaka, Richard M Stone, Daniel J DeAngelo, Anthony Letai, R Coleman Lindsley, Robert J Soiffer, Joseph H Antin
Adding venetoclax to fludarabine/busulfan RIC transplant for high risk MDS and AML is feasible, safe, and active. Blood advances (2021)
Francisco J Sánchez Rivera, Jeremy Adam Ryan, Yadira M Soto-Feliciano, Mary Clare Beytagh, Lucius Xuan, David M Feldser, Michael T Hemann, Jesse Zamudio, Nadya Dimitrova, Anthony G Letai, Tyler Jacks
Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration. Proceedings of the National Academy of Sciences of the United States of America 118 (23) (2021)
Shan Lin, Clement Larrue, Nastassja K Scheidegger, Bo Kyung Alex Seong, Neekesh V Dharia, Miljan Kuljanin, Caroline S Wechsler, Guillaume Kugener, Amanda L Robichaud, Amy Saur Conway, Thelma Mashaka, Sarah Mouche, Biniam Adane, Jeremy Adam Ryan, Joseph D Mancias, Scott T Younger, Frederica Piccioni, Lynn H Lee, Mark Wunderlich, Anthony G Letai, Jerome Tamburini, Kimberly Stegmaier
An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML. Cancer discovery (2021)
Ryan N Rys, Claudia M Wever, Dominique Geoffrion, Christophe Goncalves, Artin Ghassemian, Eugene Brailovski, Jeremy Adam Ryan, Liliana Stoica, Josée Hébert, Tina Petrogiannis-Haliotis, Svetlana Dmitrienko, Saul Frenkiel, Annette M Staiger, German Ott, Christian Steidl, David W Scott, Pierre Sesques, Sonia Del Rincon, Koren K Mann, Anthony G Letai, Nathalie A Johnson
Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling. Cancers 13 (5) (2021)
Patrick D Bhola, Eman Ahmed, Jennifer L Guerriero, Ewa Sicinska, Emily Su, Elizaveta Lavrova, Jing Ni, Otari Chipashvili, Timothy Hagan, Marissa S Pioso, Kelley McQueeney, Kimmie Ng, Andrew J Aguirre, James M Cleary, David Cocozziello, Alaba Sotayo, Jeremy Adam Ryan, Jean J Zhao, Anthony G Letai
High-throughput dynamic BH3 profiling may quickly and accurately predict effective therapies in solid tumors. Science signaling 13 (636) (2020)
John Michael Replogle, Wen Zhou, Adrianna E Amaro, James M McFarland, Mariana Villalobos-Ortiz, Jeremy Adam Ryan, Anthony Letai, Omer Yilmaz, Jason Sheltzer, Stephen J Lippard, Uri Ben-David, Angelika Amon
Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Marcel A Dammert, Johannes Brägelmann, Rachelle R Olsen, Stefanie Böhm, Niloufar Monhasery, Christopher P Whitney, Milind D Chalishazar, Hannah L Tumbrink, Matthew R Guthrie, Sebastian Klein, Abbie S Ireland, Jeremy Adam Ryan, Anna Schmitt, Annika Marx, Luka Ozretić, Roberta Castiglione, Carina Lorenz, Ron D Jachimowicz, Elmar Wolf, Roman K Thomas, John T Poirier, Reinhard Büttner, Triparna Sen, Lauren A Byers, H Christian Reinhardt, Anthony G Letai, Trudy G Oliver, Martin L Sos
MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer. Nature communications 10 (1) (2019)
Felix Seyfried, Salih Demir, Rebecca Louise Hörl, Felix Uli Stirnweiß, Jeremy Adam Ryan, Annika Scheffold, Mariana Villalobos-Ortiz, Elena Boldrin, Julia Zinngrebe, Stefanie Enzenmüller, Silvia Jenni, Yi-Chien Tsai, Beat Bornhauser, Axel Fürstberger, Johann Michael Kraus, Hans Armin Kestler, Jean-Pierre Bourquin, Stephan Stilgenbauer, Anthony Letai, Klaus-Michael Debatin, Lüder Hinrich Meyer
Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling. Cell death & disease 10 (8) (2019)
Mariana Villalobos-Ortiz, Jeremy Adam Ryan, Thelma N Mashaka, Joseph T Opferman, Anthony Letai
BH3 profiling discriminates on-target small molecule BH3 mimetics from putative mimetics. Cell death and differentiation 27 (3) (2019)
Elizabeth H Stover, Maria B Baco, Ofir Cohen, Yvonne Y Li, Elizabeth L Christie, Mukta Bagul, Amy Goodale, Yenarae Lee, Sasha Pantel, Matthew G Rees, Guo Wei, Adam G Presser, Maya K Gelbard, Weiqun Zhang, Ioannis K Zervantonakis, Patrick D Bhola, Jeremy Adam Ryan, Jennifer L Guerriero, Joan Montero, Felice J Liang, Andrew D Cherniak, Federica Piccioni, Ursula A Matulonis, David D L Bowtell, Kristopher A Sarosiek, Anthony Letai, Levi A Garraway, Cory M Johannessen, Matthew Meyerson
Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer. Molecular cancer research : MCR 17 (11) (2019)
David Lagares, Alba Santos, Paula E Grasberger, Fei Liu, Clemens K Probst, Rod A Rahimi, Norihiko Sakai, Tobias Kuehl, Jeremy Adam Ryan, Patrick Bhola, Joan Montero, Mohit Kapoor, Murray Baron, Xaralabos Varelas, Daniel J Tschumperlin, Anthony Letai, Andrew M Tager
Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis. Science translational medicine 9 (420) (2018)
Justin M Jenson, Jeremy Adam Ryan, Robert A Grant, Anthony Letai, Amy E Keating
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1. eLife 6 (2017)
Jeremy Adam Ryan, Joan Montero, James Rocco, Anthony Letai
iBH3: simple, fixable BH3 profiling to determine apoptotic priming in primary tissue by flow cytometry. Biological chemistry 397 (7) (2017)

Jeremy Adam Ryan.css-eqlu8i{font-size:small;padding-left:4px;} (Jeremy Ryan, Jeremy A Ryan)

Publication Activity (10 Years)

Top Topics

Top Venues

Jeremy Adam Ryan (Jeremy Ryan, Jeremy A Ryan)