Kevin Litchfield

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 34

Top Venues

Nature communications

Research square

Cancer research

Nature ecology & evolution

University College London

Institute of Cancer Research (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University College London Mar 02 2020

United Kingdom

Group Leader :: Cancer Institute

Francis Crick Institute Jan 01 2017 - Feb 28 2020

United Kingdom

MRC Postdoctoral Skills Development Fellow (Bioinformatics) :: Translational Cancer Therapeutics Lab

Education History

Institute of Cancer Research Sep 01 2013

United Kingdom

PHD :: Genetics

University of Leeds Sep 01 2001 - Jul 01 2004

United Kingdom

BSC :: Mathematics

Publications

Alexander Coulton, Jun Murai, Danwen Qian, Krupa Thakkar, Claire E Lewis, Kevin Litchfield
Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response. Nature communications 15 (1) (2024)
Jesse Boumelha, Andrea de Castro, Nourdine Bah, Hongui Cha, Sophie de Carné Trécesson, Sareena Rana, Mona Tomaschko, Panayiotis Anastasiou, Edurne Mugarza, Christopher Moore, Robert Goldstone, Philip East, Kevin Litchfield, Se-Hoon Lee, Miriam Molina-Arcas, Julian Downward
CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer. Cancer research (2024)
Robert Edward Hynds, Ariana Huebner, David R Pearce, Mark S Hill, Ayse U Akarca, David Allan Moore, Sophia Ward, Kate H C Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A Wilson, Oriol Pich, Carlos Martínez-Ruiz, A S Md Mukarram Hossain, Simon P Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak P Chandrasekharan, Krishna K Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A J Crosbie, Caroline Dive, Sergio A Quezada, Samuel M Janes, Mariam Jamal-Hanjani, Teresa Marafioti, null null, Nicholas McGranahan, Charles Swanton
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature communications 15 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Alexander Coulton, Jun Murai, Danwen Qian, Krupa Thakkar, Claire E Lewis, Kevin Litchfield
Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response. Nature communications 15 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Richard Culliford, Samuel E D Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex J Cornish, Lisa Browning, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, null null, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic, Richard S Houlston
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Nature communications 15 (1) (2024)
Yue Zhao, Jian Gao, Jun Wang, Fanfan Fan, Chao Cheng, Danwen Qian, Ran Guo, Yang Zhang, Ting Ye, Marcellus Augustine, Yicong Lin, Jun Shang, Hang Li, Yunjian Pan, Qingyuan Huang, Haiqing Chen, Han Han, Zhendong Gao, Qiming Wang, Shiyue Zhang, Mou Zhang, Fangqiu Fu, Yueren Yan, Shanila Fernandez Patel, Roberto Vendramin, Hui Yuan, Yawei Zhang, Jiaqing Xiang, Hong Hu, Yihua Sun, Yuan Li, Kevin Litchfield, Zhiwei Cao, Haiquan Chen
Genomic and immune heterogeneity of multiple synchronous lung adenocarcinoma at different developmental stages. Nature communications 15 (1) (2024)
Jesse Boumelha, Andrea de Castro, Nourdine Bah, Hongui Cha, Sophie de Carné Trécesson, Sareena Rana, Mona Tomaschko, Panayiotis Anastasiou, Edurne Mugarza, Christopher Moore, Robert Goldstone, Philip East, Kevin Litchfield, Se-Hoon Lee, Miriam Molina-Arcas, Julian Downward
CRISPR-Cas9 Screening Identifies KRAS-Induced COX2 as a Driver of Immunotherapy Resistance in Lung Cancer. Cancer research 84 (14) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Richard Culliford, Samuel E D Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex J Cornish, Lisa Browning, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, null null, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic, Richard S Houlston
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Nature communications 15 (1) (2024)
Richard Culliford, Samuel E D Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex J Cornish, Lisa Browning, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, null null, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic, Richard S Houlston
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Nature communications 15 (1) (2024)
Richard Culliford, Samuel E D Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex J Cornish, Lisa Browning, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, null null, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic, Richard S Houlston
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Nature communications 15 (1) (2024)
Jesse Boumelha, Andrea de Castro, Nourdine Bah, Hongui Cha, Sophie de Carné Trécesson, Sareena Rana, Mona Tomaschko, Panayiotis Anastasiou, Edurne Mugarza, Christopher Moore, Robert Goldstone, Philip East, Kevin Litchfield, Se-Hoon Lee, Miriam Molina-Arcas, Julian Downward
CRISPR-Cas9 Screening Identifies KRAS-Induced COX2 as a Driver of Immunotherapy Resistance in Lung Cancer. Cancer research 84 (14) (2024)
Robert Edward Hynds, Ariana Huebner, David R Pearce, Mark S Hill, Ayse U Akarca, David Allan Moore, Sophia Ward, Kate H C Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A Wilson, Oriol Pich, Carlos Martínez-Ruiz, A S Md Mukarram Hossain, Simon P Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak P Chandrasekharan, Krishna K Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A J Crosbie, Caroline Dive, Sergio A Quezada, Samuel M Janes, Mariam Jamal-Hanjani, Teresa Marafioti, null null, Nicholas McGranahan, Charles Swanton
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature communications 15 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Jesse Boumelha, Andrea de Castro, Nourdine Bah, Hongui Cha, Sophie de Carné Trécesson, Sareena Rana, Mona Tomaschko, Panayiotis Anastasiou, Edurne Mugarza, Christopher Moore, Robert Goldstone, Philip East, Kevin Litchfield, Se-Hoon Lee, Miriam Molina-Arcas, Julian Downward
CRISPR-Cas9 Screening Identifies KRAS-Induced COX2 as a Driver of Immunotherapy Resistance in Lung Cancer. Cancer research 84 (14) (2024)
Kevin W Ng, Jesse Boumelha, Katey S S Enfield, Jorge Almagro, Hongui Cha, Oriol Pich, Takahiro Karasaki, David A Moore, Roberto Salgado, Monica Sivakumar, George R Young, Miriam Molina-Arcas, Sophie de Carné Trécesson, Panayiotis Anastasiou, Annika Fendler, Lewis Au, Scott T C Shepherd, Carlos Martínez-Ruiz, Clare Puttick, James R M Black, Thomas B K Watkins, Hyemin Kim, Seohee Shim, Nikhil Faulkner, Jan Attig, Selvaraju Veeriah, Neil Magno, Sophia Ward, Alexander M Frankell, Maise Al Bakir, Emilia L Lim, Mark S Hill, Gareth A Wilson, Daniel E Cook, Nicolai Juul Birkbak, Axel Behrens, Nadia Yousaf, Sanjay Popat, Allan Hackshaw, null null, null null, Crispin T Hiley, Kevin Litchfield, Nicholas McGranahan, Mariam Jamal-Hanjani, James Larkin, Se-Hoon Lee, Samra Turajlic, Charles Swanton, Julian Downward, George Kassiotis
Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature (2023)
Lavinia Spain, Alexander Coulton, Irene Lobon, Andrew Rowan, Desiree Schnidrig, Scott T C Shepherd, Benjamin Shum, Fiona Byrne, Maria Goicoechea, Elisa Piperni, Lewis Au, Kim Edmonds, Eleanor Carlyle, Nikki Hunter, Alexandra Renn, Christina Messiou, Peta Hughes, Jaime Nobbs, Floris Foijer, Hilda van den Bos, Rene Wardenaar, Diana Carolina Johanna Spierings, Charlotte Spencer, Andreas Michael Schmitt, Zayd Tippu, Karla Lingard, Lauren Grostate, Kema Peat, Kayleigh Kelly, Sarah Sarker, Sarah Vaughan, Mary Mangwende, Lauren Terry, Denise Kelly, Jennifer Biano, Aida Murra, Justine Korteweg, Charlotte Lewis, Molly OFlaherty, Anne-Laure Cattin, Max Emmerich, Camille L Gerard, Husayn Ahmed Pallikonda, Joanna Lynch, Robert Mason, Aljosja Rogiers, Hang Xu, Ariana Huebner, Nicholas McGranahan, Maise Al Bakir, Jun Murai, Cristina Naceur-Lombardelli, Elaine Borg, Miriam Mitchison, David Allan Moore, Mary Falzon, Ian Proctor, Gordon W H Stamp, Emma L Nye, Kate Young, Andrew J S Furness, Lisa M Pickering, Ruby Stewart, Ula Mahadeva, Anna C Green, James M G Larkin, Kevin Litchfield, Charles Swanton, Mariam Jamal-Hanjani, Samra Turajlic
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways. Cancer discovery (2023)
Richard S Houlston, Richard Culliford, Sam Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex Cornish, Lisa Browining, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Research square (2023)
Georges Bedran, Hans-Christof Gasser, Kenneth Weke, Tongjie Wang, Dominika Bedran, Alexander Laird, Christophe Battail, Fabio Massimo Zanzotto, Catia Pesquita, Håkan Axelson, Ajitha Rajan, David J Harrison, Aleksander Palkowski, Maciej Pawlik, Maciej Parys, J Robert O'Neill, Paul M Brennan, Stefan N Symeonides, David R Goodlett, Kevin Litchfield, Robin Fahraeus, Theodore Hupp, Sachin Kote, Javier Antonio Alfaro
The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I-associated peptides. Cancer immunology research (2023)
Richard S Houlston, Richard Culliford, Sam Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex Cornish, Lisa Browining, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Research square (2023)
Aaron Javitt, Merav D Shmueli, Matthias P Kramer, Aleksandra A Kolodziejczyk, Ivan J Cohen, Lihi Radomir, Daoud Sheban, Iris Kamer, Kevin Litchfield, Elizabeta Bab-Dinitz, Oranit Zadok, Vanessa Neiens, Adi Ulman, Hila Wolf-Levy, Avital Eisenberg-Lerner, Assaf Kacen, Michal Alon, Ana Toste Rêgo, Elvira Stacher-Priehse, Michael Lindner, Ina Koch, Jair Bar, Charles Swanton, Yardena Sameuls, Yishai Levin, Paula C A da Fonseca, Eran Elinav, Nir Friedman, Silke Meiners, Yifat Merbl
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC. Nature cancer (2023)
Richard S Houlston, Richard Culliford, Sam Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex Cornish, Lisa Browining, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Research square (2023)
William Hill, Emilia L Lim, Clare E Weeden, Claudia S Y Lee, Marcellus Augustine, Kezhong Chen, Feng-Che Kuan, Fabio Marongiu, Edward J Evans, David Allan Moore, Felipe S Rodrigues, Oriol Pich, Bjorn Bakker, Hongui Cha, Renelle Myers, Febe van Maldegem, Jesse Boumelha, Selvaraju Veeriah, Andrew Rowan, Cristina Naceur-Lombardelli, Takahiro Karasaki, Monica Sivakumar, Swapnanil De, Deborah R Caswell, Ai Nagano, James R M Black, Carlos Martínez-Ruiz, Min Hyung Ryu, Ryan D Huff, Shijia Li, Marie-Julie Favé, Alastair Magness, Alejandro Suarez-Bonnet, Simon Lawrence Priestnall, Margreet Lüchtenborg, Katrina Lavelle, Joanna Pethick, Steven Hardy, Fiona E McRonald, Meng-Hung Lin, Clara I Troccoli, Moumita Ghosh, York E Miller, Daniel T Merrick, Robert L Keith, Maise Al Bakir, Chris Bailey, Mark S Hill, Lao H Saal, Yilun Chen, Anthony M George, Christopher Abbosh, Nnennaya Kanu, Se-Hoon Lee, Nicholas McGranahan, Christine D Berg, Peter D Sasieni, Richard S Houlston, Clare Turnbull, Stephen Lam, Phillip Awadalla, Eva Grönroos, Julian Downward, Tyler Jacks, Christopher Carlsten, Ilaria Malanchi, Allan Hackshaw, Kevin Litchfield, null null, James DeGregori, Mariam Jamal-Hanjani, Charles Swanton
Lung adenocarcinoma promotion by air pollutants. Nature 616 (7955) (2023)
Richard S Houlston, Richard Culliford, Sam Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex Cornish, Lisa Browining, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Research square (2023)
Richard S Houlston, Richard Culliford, Sam Lawrence, Charlie Mills, Zayd Tippu, Daniel Chubb, Alex Cornish, Lisa Browining, Ben Kinnersley, Robert Bentham, Amit Sud, Husayn Ahmed Pallikonda, Anna Frangou, Andreas J Gruber, Kevin Litchfield, David C Wedge, James Larkin, Samra Turajlic
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma. Research square (2023)
Filipe Correia Martins, Dominique-Laurent Couturier, Ines de Santiago, Carolin Margarethe Sauer, Maria Vias, Mihaela Angelova, Deborah Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa S Carnevalli, Barry R Davies, Thomas B K Watkins, Ionut-Gabriel Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew D Eldridge, Bristi Basu, Mercedes Jimenez-Linan, Andrew W Mcpherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P Shah, Iain A McNeish, Carlos Caldas, Gerard I Evan, Charles Swanton, James D Brenton
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer. Nature communications 13 (1) (2022)
Xiao Fu, Yue Zhao, Jose I Lopez, Andrew Rowan, Lewis Au, Annika Fendler, Steve Hazell, Hang Xu, Stuart Horswell, Scott T C Shepherd, Charlotte E Spencer, Lavinia Spain, Fiona Byrne, Gordon W H Stamp, Tim O'Brien, David Nicol, Marcellus Augustine, Ashish Chandra, Sarah Rudman, Antonia Toncheva, Andrew J S Furness, Lisa M Pickering, Santosh Kumar, Dow-Mu Koh, Christina Messiou, Derfel Ap Dafydd, Matthew R Orton, Simon J Doran, James Larkin, Charles Swanton, Erik Sahai, Kevin Litchfield, Samra Turajlic, null null, Paul A Bates
Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study. Nature ecology & evolution 6 (1) (2021)
Yue Zhao, Xiao Fu, Jose Ignacio López, Andrew Rowan, Lewis Au, Annika Fendler, Steve Hazell, Hang Xu, Stuart Horswell, Scott T C Shepherd, Lavinia Spain, Fiona Byrne, Gordon Stamp, Tim O'Brien, David Nicol, Marcellus Augustine, Ashish Chandra, Sarah Rudman, Antonia Toncheva, Lisa M Pickering, Erik Sahai, James Larkin, Paul A Bates, Charles Swanton, Samra Turajlic, null null, Kevin Litchfield
Selection of metastasis competent subclones in the tumour interior. Nature ecology & evolution 5 (7) (2021)
Eleonora Ottina, Veera Panova, Laura Doglio, Anastasiya Kazachenka, Georgina Cornish, Joanna Kirkpatrick, Jan Attig, George R Young, Kevin Litchfield, Tom Lesluyes, Peter Van Loo, Charles Swanton, James I MacRae, Thomas Tüting, George Kassiotis
E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion. Oncogene 40 (37) (2021)
Guangchun Han, Guoliang Yang, Dapeng Hao, Yang Lu, Kyaw Zin Thein, Benjamin Scott S Simpson, Jianfeng Chen, Ryan Sun, Omar Alhalabi, Ruiping Wang, Minghao Dang, Enyu Dai, Shaojun Zhang, Fengqi Nie, Shuangtao Zhao, Charles Guo, Ameer Hamza, Bogdan Czerniak, Chao Cheng, Arlene Siefker-Radtke, Krishna P Bhat, P Andrew Futreal, Guang Peng, Jennifer A Wargo, Weiyi Peng, Humam Kadara, Jaffer A Ajani, Charles Swanton, Kevin Litchfield, Jordi Rodon Ahnert, Jianjun Gao, Linghua Wang
9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy. Nature communications 12 (1) (2021)
Kevin Litchfield, James L Reading, Emilia L Lim, Hang Xu, Po Liu, Maise Al-Bakir, Yien Ning Sophia Wong, Andrew Rowan, Samuel A Funt, Taha Merghoub, David Perkins, Martin Lauss, Inge Marie Svane, Göran Jönsson, Javier Herrero, James Larkin, Sergio A Quezada, Matthew D Hellmann, Samra Turajlic, Charles Swanton
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity. Nature communications 11 (1) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kevin Litchfield