Tomas Yeo

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Topics

Molecular Dynamics Simulations

Plasmodium Falciparum

Pluripotent Stem Cells

Top Venues

Nature communications

Research square

Proceedings of the National Academy of Sciences of the United States of America

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R Luth, Johanna Hoshizaki, Mukul Rawat, Richard D Pearson, Kyra A Schindler, Sachel Mok, Heekuk Park, Anne-Catrin Uhlemann, Gouranga P Jana, Bikash C Maity, Benoît Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Maria G Gomez-Lorenzo, Francisco Javier Gamo, Elizabeth A Winzeler, David A Fidock, Thanat Chookajorn, Marcus Chee San Lee
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum. Nature communications 14 (1) (2023)
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, Pamela Magistrado-Coxen, Kyra A Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S Nasamu, Allison R Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M Early, Amanda K Lukens, Danny Milner, Jeremy D Furtado, Francisco-Javier Gamo, Elizabeth A Winzeler, Sarah K Volkman, Maëlle Duffey, Benoît Laleu, David A Fidock, Susan Wyllie, Jacquin C Niles, Dyann F Wirth
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation. Nature communications 14 (1) (2023)
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, Pamela Magistrado-Coxen, Kyra A Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S Nasamu, Allison R Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M Early, Amanda K Lukens, Danny Milner, Jeremy D Furtado, Francisco-Javier Gamo, Elizabeth A Winzeler, Sarah K Volkman, Maëlle Duffey, Benoît Laleu, David A Fidock, Susan Wyllie, Jacquin C Niles, Dyann F Wirth
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation. Nature communications 14 (1) (2023)
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, Pamela Magistrado-Coxen, Kyra A Schindler, Victoriano Corpas-Lopez, Tomas Yeo, Sachel Mok, Sumanta Dey, Sebastian Smick, Armiyaw S Nasamu, Allison R Demas, Rachel Milne, Natalie Wiedemar, Victoria Corey, Maria De Gracia Gomez-Lorenzo, Virginia Franco, Angela M Early, Amanda K Lukens, Danny Milner, Jeremy D Furtado, Francisco-Javier Gamo, Elizabeth A Winzeler, Sarah K Volkman, Maëlle Duffey, Benoît Laleu, David A Fidock, Susan Wyllie, Jacquin C Niles, Dyann F Wirth
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation. Nature communications 14 (1) (2023)
Sachel Mok, Tomas Yeo, Davin Hong, Melanie J Shears, Leila S Ross, Kurt E Ward, Satish K Dhingra, Mariko Kanai, Jessica L Bridgford, Abhai K Tripathi, Godfree Mlambo, Anna Y Burkhard, Megan R Ansbro, Kate J Fairhurst, Eva Gil Iturbe, Heekuk Park, Felix D Rozenberg, Jonathan Kim, Filippo Mancia, Rick M Fairhurst, Matthias Quick, Anne-Catrin Uhlemann, Photini Sinnis, David A Fidock
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness. Science advances 9 (45) (2023)
Leann Tilley, Stanley C Xie, Yinuo Wang, Craig J Morton, Riley Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse Dunn, Madeline Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Katie Fairhurst, Tomas Yeo, Okan Yildirim, Mathamsanqa Bhebhe, Dana Klug, Peter J Rutledge, Luiz Godoy, Sumanta Dey, Mariana De Souza, Jair Siqueira-Neto, Nutpakal Ketprasit, Yawei Du, Mona Amini, Gerald J Shami, Shuai Nie, Nicholas A Williamson, Gouranga Jana, Bikash Maity, Patrick Thomson, Thomas Foley, Duangkamon Loesbanluechai, Tanya Puhalovich, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus Lee, Elizabeth Winzeler, Michael D W Griffin, Matthew H Todd
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Research square (2023)
Deyun Qiu, Jinxin V Pei, James E O Rosling, Vandana Thathy, Dongdi Li, Yi Xue, John D Tanner, Jocelyn Sietsma Penington, Yi Tong Vincent Aw, Jessica Yi Han Aw, Guoyue Xu, Abhai K Tripathi, Nina F Gnadig, Tomas Yeo, Kate J Fairhurst, Barbara H Stokes, James M Murithi, Krittikorn Kümpornsin, Heath Hasemer, Adelaide S M Dennis, Melanie C Ridgway, Esther K Schmitt, Judith Straimer, Anthony T Papenfuss, Marcus Chee San Lee, Ben Corry, Photini Sinnis, David A Fidock, Giel G van Dooren, Kiaran Kirk, Adele M Lehane
A G358S mutation in the Plasmodium falciparum Na + pump PfATP4 confers clinically-relevant resistance to cipargamin. Nature communications 13 (1) (2022)
Laura E de Vries, Patrick A M Jansen, Catalina Barcelo, Justin Munro, Julie M J Verhoef, Charisse Flerida A Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M Bolscher, Claudia Demarta-Gatsi, Rob W M Henderson, Tonnie Huijs, Karin M J Koolen, Patrick K Tumwebaze, Tomas Yeo, Anna C C Aguiar, Inigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael Victorio Carvalho Guido, María Belén Jiménez-Diaz, Dhelio Batista Pereira, Rosemary Rochford, Camille Roesch, Laura Maria Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A Cooper, Philip J Rosenthal, Robert W Sauerwein, Joost Schalkwijk, Pedro H H Hermkens, Roger V Bonnert, Brice Campo, David A Fidock, Manuel Llinás, Jacquin C Niles, Taco W A Kooij, Koen J Dechering
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature communications 13 (1) (2022)
Barbara H Stokes, Satish K Dhingra, Kelly Rubiano, Sachel Mok, Judith Straimer, Nina F Gnädig, Ioanna Deni, Kyra A Schindler, Jade R Bath, Kurt E Ward, Josefine Striepen, Tomas Yeo, Leila S Ross, Eric Legrand, Frédéric Ariey, Clark H Cunningham, Issa M Souleymane, Adama Gansané, Romaric Nzoumbou-Boko, Claudette Ndayikunda, Abdunoor M Kabanywanyi, Aline Uwimana, Samuel J Smith, Olimatou Kolley, Mathieu Ndounga, Marian Warsame, Rithea Leang, Francois H Nosten, Timothy Jc Anderson, Philip J Rosenthal, Didier Ménard, David A Fidock
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness. eLife 10 (2021)
Sachel Mok, Barbara H Stokes, Nina F Gnädig, Leila S Ross, Tomas Yeo, Chanaki Amaratunga, Erik Allman, Lev Solyakov, Andrew R Bottrill, Jaishree Tripathi, Rick M Fairhurst, Manuel Llinás, Zbynek Bozdech, Andrew B Tobin, David A Fidock
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival. Nature communications 12 (1) (2021)
Stanley C Xie, Riley D Metcalfe, Hirotake Mizutani, Tanya Puhalovich, Eric Hanssen, Craig J Morton, Yawei Du, Con Dogovski, Shih-Chung Huang, Jeffrey Ciavarri, Paul Hales, Robert J Griffin, Lawrence H Cohen, Bei-Ching Chuang, Sergio Wittlin, Ioanna Deni, Tomas Yeo, Kurt E Ward, Daniel C Barry, Boyin Liu, David L Gillett, Benigno F Crespo-Fernandez, Sabine Ottilie, Nimisha Mittal, Alisje Churchyard, Daniel Ferguson, Anna Caroline Campos Aguiar, Rafael Victorio Carvalho Guido, Jake Baum, Kirsten K Hanson, Elizabeth A Winzeler, Francisco Javier Gamo, David A Fidock, Delphine Baud, Michael W Parker, Stephen Brand, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America 118 (39) (2021)
James M Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F Gnädig, Charisse Flerida A Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Melanie Rouillier, Mohammed H Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Richard N Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A Cooper, Philip J Rosenthal, Laura M Sanz, Francisco Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Inigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudie, Jacquin C Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A Fidock, Didier Leroy
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance. Science translational medicine 13 (603) (2021)
Leila S Ross, Satish K Dhingra, Sachel Mok, Tomas Yeo, Kathryn J Wicht, Krittikorn Kumpornsin, Shannon Takala-Harrison, Benoit Witkowski, Rick M Fairhurst, Frederic Ariey, Didier Menard, David A Fidock
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine. Nature communications 9 (1) (2018)