Leann Tilley

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Topics

Pluripotent Stem Cells

Plasmodium Falciparum

Top Venues

Nature communications

Cellular microbiology

Communications biology

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Jiahong Li, Gerald J Shami, Benjamin Liffner, Ellie H-J Cho, Filip Braet, Manoj T Duraisingh, Sabrina Absalon, Matthew W A Dixon, Leann Tilley
Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Jiahong Li, Gerald J Shami, Benjamin Liffner, Ellie H-J Cho, Filip Braet, Manoj T Duraisingh, Sabrina Absalon, Matthew W A Dixon, Leann Tilley
Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus. Nature communications 15 (1) (2024)
Jiahong Li, Gerald J Shami, Benjamin Liffner, Ellie H-J Cho, Filip Braet, Manoj T Duraisingh, Sabrina Absalon, Matthew W A Dixon, Leann Tilley
Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus. Nature communications 15 (1) (2024)
Sophie Collier, Emma Pietsch, Madeline Dans, Dawson B Ling, Tatyana A Tavella, Sash Lopaticki, Danushka S Marapana, Mohini A Shibu, Dean Andrew, Snigdha Tiash, Paul J McMillan, Paul R Gilson, Leann Tilley, Matthew W A Dixon
Plasmodium falciparum formins are essential for invasion and sexual stage development. Communications biology 6 (1) (2023)
Leann Tilley, Stanley C Xie, Yinuo Wang, Craig J Morton, Riley Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse Dunn, Madeline Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Katie Fairhurst, Tomas Yeo, Okan Yildirim, Mathamsanqa Bhebhe, Dana Klug, Peter J Rutledge, Luiz Godoy, Sumanta Dey, Mariana De Souza, Jair Siqueira-Neto, Nutpakal Ketprasit, Yawei Du, Mona Amini, Gerald J Shami, Shuai Nie, Nicholas A Williamson, Gouranga Jana, Bikash Maity, Patrick Thomson, Thomas Foley, Duangkamon Loesbanluechai, Tanya Puhalovich, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus Lee, Elizabeth Winzeler, Michael D W Griffin, Matthew H Todd
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Research square (2023)
Benjamin Liffner, Juan Miguel Balbin, Gerald J Shami, Ghizal Siddiqui, Jan Strauss, Sonja Frolich, Gary K Heinemann, Ella May Edwards, Arne Alder, Jan Stephan Wichers-Misterek, Darren J Creek, Leann Tilley, Matthew W A Dixon, Tim-Wolf Gilberger, Danny W Wilson
Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites. Communications biology 5 (1) (2022)
Stanley C Xie, Riley D Metcalfe, Elyse A Dunn, Craig J Morton, Shih-Chung Huang, Tanya Puhalovich, Yawei Du, Sergio Wittlin, Shuai Nie, Madeline R Luth, Liting Ma, Mi-Sook Kim, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Carlo Giannangelo, Fiona J Houghton, Alisje Churchyard, Mufuliat T Famodimu, Daniel C Barry, David L Gillett, Sumanta Dey, Clara C Kosasih, William Newman, Jacquin C Niles, Marcus Chee San Lee, Jake Baum, Sabine Ottilie, Elizabeth A Winzeler, Darren John Creek, Nicholas A Williamson, Michael W Parker, Stephen Brand, Steven P Langston, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy. Science (New York, N.Y.) 376 (6597) (2022)
Jiahong Li, Gerald J Shami, Ellie H-J Cho, Boyin Liu, Eric Hanssen, Matthew W A Dixon, Leann Tilley
Repurposing the mitotic machinery to drive cellular elongation and chromatin reorganisation in Plasmodium falciparum gametocytes. Nature communications 13 (1) (2022)
Yawei Du, Carlo Giannangelo, Wei He, Gerald J Shami, Wenya Zhou, Tuo Yang, Darren John Creek, Con Dogovski, Xinsong Li, Leann Tilley
Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance. Antimicrobial agents and chemotherapy 66 (5) (2022)
Simon A Cobbold, Madel V Tutor, Philip M Frasse, Emma McHugh, Markus Karnthaler, Darren J Creek, Audrey R Odom John, Leann Tilley, Stuart A Ralph, Malcolm J McConville
Non-canonical metabolic pathways in the malaria parasite detected by isotope-tracing metabolomics. Molecular systems biology 17 (4) (2021)
Lydia Mata-Cantero, Stanley C Xie, Mercedes García, Joanne Coyle, Raquel Fernandez, Alvaro Cortes Cabrera, David L Gillett, Benigno Crespo, Francisco Javier Gamo, Esther Fernandez, Leann Tilley, Maria G Gomez-Lorenzo
High Throughput Screening to Identify Selective and Nonpeptidomimetic Proteasome Inhibitors As Antimalarials. ACS infectious diseases 7 (6) (2021)
Stanley C Xie, Riley D Metcalfe, Hirotake Mizutani, Tanya Puhalovich, Eric Hanssen, Craig J Morton, Yawei Du, Con Dogovski, Shih-Chung Huang, Jeffrey Ciavarri, Paul Hales, Robert J Griffin, Lawrence H Cohen, Bei-Ching Chuang, Sergio Wittlin, Ioanna Deni, Tomas Yeo, Kurt E Ward, Daniel C Barry, Boyin Liu, David L Gillett, Benigno F Crespo-Fernandez, Sabine Ottilie, Nimisha Mittal, Alisje Churchyard, Daniel Ferguson, Anna Caroline Campos Aguiar, Rafael Victorio Carvalho Guido, Jake Baum, Kirsten K Hanson, Elizabeth A Winzeler, Francisco Javier Gamo, David A Fidock, Delphine Baud, Michael W Parker, Stephen Brand, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America 118 (39) (2021)
Tatyana Almeida Tavella, Noeli Soares Melo da Silva, Natalie Spillman, Ana Carolina Andrade Vitor Kayano, Gustavo Capatti Cassiano, Adrielle Ayumi Vasconcelos, Antônio Pedro Camargo, Djane Clarys Baia da Silva, Diana Fontinha, Luis Carlos Salazar Alvarez, Letícia Tiburcio Ferreira, Kaira Cristina Peralis Tomaz, Bruno Junior Neves, Ludimila Dias Almeida, Daniel Youssef Bargieri, Marcus Vinicius Guimarães de Lacerda, Pedro Vitor Lemos Cravo, Per Sunnerhagen, Miguel Prudêncio, Carolina Horta Andrade, Stefanie Costa Pinto Lopes, Marcelo Falsarella Carazzolle, Leann Tilley, Elizabeth Bilsland, Júlio César Borges, Fabio Trindade Maranhão Costa
Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity. ACS infectious diseases 7 (4) (2021)
Arman Namvar, Adam J Blanch, Matthew W Dixon, Olivia M S Carmo, Boyin Liu, Snigdha Tiash, Oliver Looker, Dean Andrew, Li-Jin Chan, Wai-Hong Tham, Peter V S Lee, Vijayaraghavan Rajagopal, Leann Tilley
Surface area-to-volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels. Cellular microbiology 23 (1) (2020)
Oliver Looker, Adam J Blanch, Boyin Liu, Juan Nunez-Iglesias, Paul J McMillan, Leann Tilley, Matthew W A Dixon
The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly. PLoS pathogens 15 (5) (2019)
Laure Dumont, Mark B Richardson, Phillip van der Peet, Danushka S Marapana, Tony Triglia, Matthew W A Dixon, Alan F Cowman, Spencer J Williams, Leann Tilley, Malcolm J McConville, Simon A Cobbold
The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum. mBio 10 (6) (2019)
Boyin Liu, Adam J Blanch, Arman Namvar, Olivia Carmo, Snigdha Tiash, Dean Andrew, Eric Hanssen, Vijay Rajagopal, Matthew W A Dixon, Leann Tilley
Multimodal analysis of Plasmodium knowlesi-infected erythrocytes reveals large invaginations, swelling of the host cell, and rheological defects. Cellular microbiology 21 (5) (2019)
Kit Kennedy, Simon A Cobbold, Eric Hanssen, Jakob Birnbaum, Natalie J Spillman, Emma McHugh, Hannah J Brown, Leann Tilley, Tobias Spielmann, Malcolm J McConville, Stuart A Ralph
Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking. PLoS biology 17 (7) (2019)
Stanley C Xie, Riley D Metcalfe, Eric Hanssen, Tuo Yang, David L Gillett, Andrew P Leis, Craig J Morton, Michael J Kuiper, Michael W Parker, Natalie J Spillman, Wilson Wong, Christopher Tsu, Lawrence R Dick, Michael D W Griffin, Leann Tilley
The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nature microbiology 4 (11) (2019)
Stanley C Xie, David L Gillett, Natalie J Spillman, Christopher Tsu, Madeline R Luth, Sabine Ottilie, Sandra Duffy, Alexandra E Gould, Paul Hales, Benjamin A Seager, Carlie L Charron, Frank Bruzzese, Xiaofeng Yang, Xiansi Zhao, Shih-Chung Huang, Craig A Hutton, Jeremy N Burrows, Elizabeth A Winzeler, Vicky M Avery, Lawrence R Dick, Leann Tilley
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome. Journal of medicinal chemistry 61 (22) (2018)
Hong Ming Huang, Denis Carolin Bauer, Patrick M Lelliott, Matthew W A Dixon, Leann Tilley, Brendan J McMorran, Simon J Foote, Gaetan Burgio
Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria. G3 (Bethesda, Md.) 7 (9) (2017)