Alexander Titz (Matthias Gehringer)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 30

Top Topics

Fluorescent Probe

Top Venues

Journal of medicinal chemistry

Drug design, development and therapy

Pharmaceuticals (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Laura Hillebrand, Xiaojun Julia Liang, Ricardo A M Serafim, Alexander Titz
Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update. Journal of medicinal chemistry 67 (10) (2024)
Laura Hillebrand, Xiaojun Julia Liang, Ricardo A M Serafim, Alexander Titz
Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update. Journal of medicinal chemistry 67 (10) (2024)
Laura Hillebrand, Xiaojun Julia Liang, Ricardo A M Serafim, Alexander Titz
Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update. Journal of medicinal chemistry (2024)
David E Heppner, Blessing C Ogboo, Daniel A Urul, Earl W May, Erik M Schaefer, Andrew S Murkin, Alexander Titz
Demystifying Functional Parameters for Irreversible Enzyme Inhibitors. Journal of medicinal chemistry (2024)
Theresa Klett, Martin Schwer, Larissa N Ernst, Marc U Engelhardt, Simon J Jaag, Benedikt Masberg, Cornelius Knappe, Michael Lämmerhofer, Alexander Titz, Frank M Boeckler
Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53. Drug design, development and therapy 18 (2024)
Theresa Klett, Martin Schwer, Larissa N Ernst, Marc U Engelhardt, Simon J Jaag, Benedikt Masberg, Cornelius Knappe, Michael Lämmerhofer, Alexander Titz, Frank M Boeckler
Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53. Drug design, development and therapy 18 (2024)
Stefan A Laufer, Alexander Titz, Alexander Titz
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany. Journal of medicinal chemistry (2024)
Moritz Schwarz, Maksym Kurkunov, Florian Wittlinger, Ramona Rudalska, Guiqun Wang, Martin Peter Schwalm, Alexander Rasch, Benedikt Wagner, Stefan A Laufer, Stefan Knapp, Daniel Dauch, Alexander Titz
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S N Ar Electrophiles. Journal of medicinal chemistry (2024)
Stefan A Laufer, Alexander Titz, Alexander Titz
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany. Journal of medicinal chemistry 67 (4) (2024)
Ricardo A M Serafim, Alexander Titz, Chiara Borsari
Targeted Covalent Inhibitors in Drug Discovery, Chemical Biology and Beyond. Pharmaceuticals (Basel, Switzerland) 17 (2) (2024)
Stefan A Laufer, Alexander Titz, Alexander Titz
Journal of Medicinal Chemistry Collection: Drug Discovery in Germany. Journal of medicinal chemistry 67 (4) (2024)
David E Heppner, Blessing C Ogboo, Daniel A Urul, Earl W May, Erik M Schaefer, Andrew S Murkin, Alexander Titz
Demystifying Functional Parameters for Irreversible Enzyme Inhibitors. Journal of medicinal chemistry (2024)
Ricardo A M Serafim, Alexander Titz, Chiara Borsari
Targeted Covalent Inhibitors in Drug Discovery, Chemical Biology and Beyond. Pharmaceuticals (Basel, Switzerland) 17 (2) (2024)
Moritz Schwarz, Maksym Kurkunov, Florian Wittlinger, Ramona Rudalska, Guiqun Wang, Martin Peter Schwalm, Alexander Rasch, Benedikt Wagner, Stefan A Laufer, Stefan Knapp, Daniel Dauch, Alexander Titz
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S N Ar Electrophiles. Journal of medicinal chemistry 67 (8) (2024)
Matthias Schiedel, Philipp Barbie, Felix Pape, Marta Pinto, Andrea Unzue Lopez, María Méndez, Gerhard Hessler, Daniel Merk, Alexander Titz, Christina Lamers
We are MedChem: The Frontiers in Medicinal Chemistry 2024. ChemMedChem (2024)
Theresa Klett, Martin Schwer, Larissa N Ernst, Marc U Engelhardt, Simon J Jaag, Benedikt Masberg, Cornelius Knappe, Michael Lämmerhofer, Alexander Titz, Frank M Boeckler
Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53. Drug design, development and therapy 18 (2024)
Alexander Titz, Felix Pape, María Méndez, Philipp Barbie, Andrea Unzue Lopez, Julien Lefranc, Franca-Maria Klingler, Gerhard Hessler, Thierry Langer, Eleonora Diamanti, Matthias Schiedel
Back in Person: Frontiers in Medicinal Chemistry 2023. ChemMedChem (2023)
Stefan A Laufer, Jürgen Bajorath, Alexander Titz, Nathanael S Gray, Stephen V Frye, Dennis C Liotta
Publication Criteria and Requirements for Studies on Protein Kinase Inhibitors─What Is Expected? Journal of medicinal chemistry 65 (10) (2022)
Carine M Abdelmalek, Zexi Hu, Thales Kronenberger, Jenni Küblbeck, Franziska J M Kinnen, Salma S Hesse, Afsin Malik, Mark Kudolo, Raimund Niess, Alexander Titz, Lars Zender, Paula A Witt-Enderby, Darius P Zlotos, Stefan A Laufer
Gefitinib-Tamoxifen Hybrid Ligands as Potent Agents against Triple-Negative Breast Cancer. Journal of medicinal chemistry 65 (6) (2022)
Ricardo A M Serafim, André da Silva Santiago, Martin P Schwalm, Zexi Hu, Caio V Dos Reis, Jessica E Takarada, Priscila Mezzomo, Katlin B Massirer, Mark Kudolo, Stefan Gerstenecker, Apirat Chaikuad, Lars Zender, Stefan Knapp, Stefan A Laufer, Rafael Miguez Couñago, Alexander Titz
Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor. Journal of medicinal chemistry 65 (4) (2022)
Eleonora Diamanti, María Méndez, Tatjana Ross, Christian A Kuttruff, Julien Lefranc, Franca-Maria Klingler, Franz von Nussbaum, Manfred Jung, Alexander Titz
Frontiers in Medicinal Chemistry 2022 Goes Virtual. ChemMedChem 17 (21) (2022)
Ricardo A M Serafim, Jonathan M Elkins, William J Zuercher, Stefan A Laufer, Alexander Titz
Chemical Probes for Understudied Kinases: Challenges and Opportunities. Journal of medicinal chemistry (2021)
Louisa Warryn, Jean-Pierre Dangy, Philipp Gersbach, Alexander Titz, Karl-Heinz Altmann, Gerd Pluschke
An Antigen Capture Assay for the Detection of Mycolactone, the Polyketide Toxin of Mycobacterium ulcerans. Journal of immunology (Baltimore, Md. : 1950) 206 (11) (2021)
Stefan Gerstenecker, Lisa Haarer, Martin Schröder, Mark Kudolo, Martin Peter Schwalm, Valentin Wydra, Ricardo A M Serafim, Apirat Chaikuad, Stefan Knapp, Stefan A Laufer, Alexander Titz
Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2). Cancers 13 (20) (2021)
Alexander Titz
Covalent inhibitors: back on track? Future medicinal chemistry 12 (15) (2020)
Michael Forster, Xiaojun Julia Liang, Martin Schröder, Stefan Gerstenecker, Apirat Chaikuad, Stefan Knapp, Stefan A Laufer, Alexander Titz
Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK. International journal of molecular sciences 21 (23) (2020)
Alexander Titz, Stefan A Laufer
Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology. Journal of medicinal chemistry 62 (12) (2019)
Alexander Titz, Patrick Mäder, Philipp Gersbach, Bernhard Pfeiffer, Nicole Scherr, Jean-Pierre Dangy, Gerd Pluschke, Karl-Heinz Altmann
Configurationally Stabilized Analogs of M. ulcerans Exotoxins Mycolactones A and B Reveal the Importance of Side Chain Geometry for Mycolactone Virulence. Organic letters 21 (15) (2019)
Dan Chen, Alexander Titz, Sonja Lorenz
Developing Small-Molecule Inhibitors of HECT-Type Ubiquitin Ligases for Therapeutic Applications: Challenges and Opportunities. Chembiochem : a European journal of chemical biology 19 (20) (2018)
Michael Forster, Apirat Chaikuad, Teodor Dimitrov, Eva Döring, Julia Holstein, Benedict-Tilman Berger, Alexander Titz, Kamran Ghoreschi, Susanne Müller, Stefan Knapp, Stefan A Laufer
Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold. Journal of medicinal chemistry 61 (12) (2018)