Jonathan M Elkins (Jon M Elkins)

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 21

Top Venues

Journal of medicinal chemistry

Scientific reports

ChemMedChem

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Fernando H de Souza Gama, Luiz A Dutra, Michael Hawgood, Caio Vinícius Dos Reis, Ricardo A M Serafim, Marcos A Ferreira, Bruno V M Teodoro, Jéssica Emi Takarada, André da Silva Santiago, Dimitrios-Ilias Balourdas, Ann-Sofie Nilsson, Bruno Urien, Vitor M Almeida, Carina Gileadi, Priscila Z Ramos, Anita Salmazo, Stanley N S Vasconcelos, Micael Rodrigues Cunha, Susanne Müller, Stefan Knapp, Katlin Brauer Massirer, Jonathan M Elkins, Opher Gileadi, Alessandra Mascarello, Bennie B L G Lemmens, Cristiano R W Guimarães, Hatylas Azevedo, Rafael Miguez Couñago
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε. Journal of medicinal chemistry 67 (11) (2024)
Esra Balıkçı, Anne-Sophie M C Marques, Ludwig G Bauer, Raina Seupel, James M Bennett, Brigitt Raux, Karly Buchan, Klemensas Simelis, Usha Singh, Catherine Rogers, Jennifer Ward, Carol Cheng, Tamas Szommer, Kira Schützenhofer, Jonathan M Elkins, David L Sloman, Ivan Ahel, Oleg Fedorov, Paul E Brennan, Kilian V M Huber
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist. Journal of medicinal chemistry 67 (9) (2024)
Esra Balıkçı, Anne-Sophie M C Marques, Ludwig G Bauer, Raina Seupel, James M Bennett, Brigitt Raux, Karly Buchan, Klemensas Simelis, Usha Singh, Catherine Rogers, Jennifer Ward, Carol Cheng, Tamas Szommer, Kira Schützenhofer, Jonathan M Elkins, David L Sloman, Ivan Ahel, Oleg Fedorov, Paul E Brennan, Kilian V M Huber
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist. Journal of medicinal chemistry 67 (9) (2024)
Fernando H de Souza Gama, Luiz A Dutra, Michael Hawgood, Caio Vinícius Dos Reis, Ricardo A M Serafim, Marcos A Ferreira, Bruno V M Teodoro, Jéssica Emi Takarada, André da Silva Santiago, Dimitrios-Ilias Balourdas, Ann-Sofie Nilsson, Bruno Urien, Vitor M Almeida, Carina Gileadi, Priscila Z Ramos, Anita Salmazo, Stanley N S Vasconcelos, Micael Rodrigues Cunha, Susanne Müller, Stefan Knapp, Katlin Brauer Massirer, Jonathan M Elkins, Opher Gileadi, Alessandra Mascarello, Bennie B L G Lemmens, Cristiano R W Guimarães, Hatylas Azevedo, Rafael Miguez Couñago
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε. Journal of medicinal chemistry (2024)
Esra Balıkçı, Anne-Sophie M C Marques, Ludwig G Bauer, Raina Seupel, James M Bennett, Brigitt Raux, Karly Buchan, Klemensas Simelis, Usha Singh, Catherine Rogers, Jennifer Ward, Carol Cheng, Tamas Szommer, Kira Schützenhofer, Jonathan M Elkins, David L Sloman, Ivan Ahel, Oleg Fedorov, Paul E Brennan, Kilian V M Huber
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist. Journal of medicinal chemistry (2024)
Esra Balıkçı, Anne-Sophie M C Marques, Ludwig G Bauer, Raina Seupel, James M Bennett, Brigitt Raux, Karly Buchan, Klemensas Simelis, Usha Singh, Catherine Rogers, Jennifer Ward, Carol Cheng, Tamas Szommer, Kira Schützenhofer, Jonathan M Elkins, David L Sloman, Ivan Ahel, Oleg Fedorov, Paul E Brennan, Kilian V M Huber
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist. Journal of medicinal chemistry 67 (9) (2024)
Ross J Collins, Hyunah Lee, D Heulyn Jones, Jonathan M Elkins, Jason A Gillespie, Carys Thomas, Alex G Baldwin, Kimberley Jones, Loren Waters, Marie Paine, John R Atack, Simon E Ward, Olivera Grubisha, David W Foley
Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity. Journal of medicinal chemistry 65 (20) (2022)
Ricardo A M Serafim, Fiona J Sorrell, Benedict-Tilmann Berger, Ross J Collins, Stanley N S Vasconcelos, Katlin B Massirer, Stefan Knapp, James Bennett, Oleg Fedorov, Hitesh Patel, William J Zuercher, Jonathan M Elkins
Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold. Journal of medicinal chemistry 64 (18) (2021)
Ricardo A M Serafim, Jonathan M Elkins, William J Zuercher, Stefan A Laufer, Alexander Titz
Chemical Probes for Understudied Kinases: Challenges and Opportunities. Journal of medicinal chemistry (2021)
Scott H Henderson, Fiona Sorrell, James Bennett, Oleg Fedorov, Marcus T Hanley, Paulo H Godoi, Roberta Ruela de Sousa, Sean W Robinson, Alexander Ashall-Kelly, Iva Hopkins Navratilova, Daryl S Walter, Jonathan M Elkins, Simon E Ward
Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors. Journal of medicinal chemistry 64 (15) (2021)
Mahmood M Alam, Ana Sanchez-Azqueta, Omar Janha, Erika L Flannery, Amit Mahindra, Kopano Mapesa, Aditya B Char, Dev Sriranganadane, Nicolas M B Brancucci, Yevgeniya Antonova-Koch, Kathryn Crouch, Nelson Victor Simwela, Scott B Millar, Jude Akinwale, Deborah Mitcheson, Lev Solyakov, Kate Dudek, Carolyn Jones, Cleofé Zapatero, Christian Doerig, Davis C Nwakanma, Maria Jesús Vázquez, Gonzalo Colmenarejo, Maria Jose Lafuente-Monasterio, Maria Luisa Leon, Paulo H C Godoi, Jonathan M Elkins, Andrew P Waters, Andrew G Jamieson, Elena Fernández Álvaro, Lisa C Ranford-Cartwright, Matthias Marti, Elizabeth A Winzeler, Francisco Javier Gamo, Andrew B Tobin
Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science (New York, N.Y.) 365 (6456) (2020)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Carrow I Wells, Jonathan M Elkins, William J Zuercher, Graham J Tizzard, Antti Poso
Design and Analysis of the 4-Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure-Activity Relationships. ChemMedChem 15 (1) (2019)
Gerson S Profeta, Caio V Dos Reis, André da Silva Santiago, Paulo H C Godoi, Angela M Fala, Carrow I Wells, Roger Sartori, Anita P T Salmazo, Priscila Zonzini Ramos, Katlin B Massirer, Jonathan M Elkins, David Harold Drewry, Opher Gileadi, Rafael M Couñago
Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors. Scientific reports 9 (1) (2019)
Kamal R Abdul Azeez, Sneha Chatterjee, Channing Yu, Todd R Golub, Frank Sobott, Jonathan M Elkins
Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP. Nature communications 10 (1) (2019)
Fiona J Sorrell, Lena Marie Kilian, Jonathan M Elkins
Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis. The Biochemical journal 476 (7) (2019)
André da Silva Santiago, Rafael M Couñago, Priscila Zonzini Ramos, Paulo H C Godoi, Katlin B Massirer, Opher Gileadi, Jonathan M Elkins
Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors. Scientific reports 8 (1) (2018)
Susanne Müller, Suzanne Ackloo, Cheryl H Arrowsmith, Marcus Bauser, Jeremy L Baryza, Julian Blagg, Jark Böttcher, Chas Bountra, Peter J Brown, Mark E Bunnage, Adrian J Carter, David Damerell, Volker Dötsch, David H Drewry, Aled M Edwards, James Edwards, Jonathan M Elkins, Christian Fischer, Stephen V Frye, Andreas Gollner, Charles E Grimshaw, Adriaan IJzerman, Thomas Hanke, Ingo V Hartung, Steve Hitchcock, Trevor Howe, Terry V Hughes, Stefan Laufer, Volkhart Mj Li, Spiros Liras, Brian D Marsden, Hisanori Matsui, John Mathias, Ronan C O'Hagan, Dafydd R Owen, Vineet Pande, Daniel Rauh, Saul H Rosenberg, Bryan L Roth, Natalie S Schneider, Cora Scholten, Kumar Singh Saikatendu, Anton Simeonov, Masayuki Takizawa, Chris Tse, Paul R Thompson, Daniel K Treiber, Amélia Yi Viana, Carrow I Wells, Timothy M Willson, William J Zuercher, Stefan Knapp, Anke Mueller-Fahrnow
Donated chemical probes for open science. eLife 7 (2018)
Supojjanee Sansook, Cory A Ocasio, Iain J Day, Graham J Tizzard, Simon J Coles, Oleg Fedorov, James M Bennett, Jonathan M Elkins, John Spencer
Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety. Organic & biomolecular chemistry 15 (40) (2018)
Talita D Melo-Hanchuk, Priscila Ferreira Slepicka, Gabriela Vaz Meirelles, Fernanda Luisa Basei, Diogo Ventura Lovato, Daniela Campos Granato, Bianca Alves Pauletti, Romenia Ramos Domingues, Adriana Franco Paes Leme, Alessandra Luiza Pelegrini, Guido Lenz, Stefan Knapp, Jonathan M Elkins, Jörg Kobarg
NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin. Scientific reports 7 (1) (2017)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Paulo H Godoi, Michael P East, Graham J Tizzard, Lee M Graves, Gary L Johnson, Ronna E Dornsife, Carrow I Wells, Jonathan M Elkins, Timothy M Willson, William J Zuercher
Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem 13 (1) (2017)
Tinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, Sarah E Dixon-Clarke, Brian J Abraham, Ann K Greifenberg, Scott B Ficarro, Jonathan M Elkins, Yanke Liang, Nancy M Hannett, Theresa Manz, Mingfeng Hao, Bartlomiej Bartkowiak, Arno L Greenleaf, Jarrod A Marto, Matthias Geyer, Alex N Bullock, Richard A Young, Nathanael S Gray
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nature chemical biology 12 (10) (2016)
Jonathan M Elkins, Vita Fedele, Marta Szklarz, Kamal R Abdul Azeez, Eidarus Salah, Jowita Mikolajczyk, Sergei Romanov, Nikolai Sepetov, Xi-Ping Huang, Bryan L Roth, Ayman Al Haj Zen, Denis Fourches, Eugene Muratov, Alex Tropsha, Joel Morris, Beverly A Teicher, Mark Kunkel, Eric Polley, Karen E Lackey, Francis L Atkinson, John P Overington, Paul Bamborough, Susanne Müller, Daniel J Price, Timothy M Willson, David H Drewry, Stefan Knapp, William J Zuercher
Comprehensive characterization of the Published Kinase Inhibitor Set. Nature biotechnology 34 (1) (2015)

Jonathan M Elkins.css-eqlu8i{font-size:small;padding-left:4px;} (Jon M Elkins)

Publication Activity (10 Years)

Top Topics

Top Venues

Jonathan M Elkins (Jon M Elkins)