Dalia Barsyte-Lovejoy

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 30

Top Venues

Nature communications

Nature chemical biology

Communications biology

RSC medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Lei Shen, Xiaokuang Ma, Yuanyuan Wang, Zhihao Wang, Yi Zhang, Hoang Quoc Hai Pham, Xiaoqun Tao, Yuehua Cui, Jing Wei, Dimitri Lin, Tharindumala Abeywanada, Swanand Hardikar, Levon Halabelian, Noah Smith, Jiameng Dan, Dalia Barsyte-Lovejoy, Shenfeng Qiu, Yi Xing, Yanzhong Yang
Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing. Nature communications 15 (1) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology 20 (9) (2024)
Germanna Lima Righetto, Yanting Yin, David M Duda, Victoria Vu, Magdalena M Szewczyk, Hong Zeng, Yanjun Li, Peter Loppnau, Tony Mei, Yen-Yen Li, Alma Seitova, Aaron N Patrick, Jean-Francois Brazeau, Charu Chaudhry, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Levon Halabelian
Probing the CRL4 DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons. PNAS nexus 3 (4) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology 20 (9) (2024)
Lei Shen, Xiaokuang Ma, Yuanyuan Wang, Zhihao Wang, Yi Zhang, Hoang Quoc Hai Pham, Xiaoqun Tao, Yuehua Cui, Jing Wei, Dimitri Lin, Tharindumala Abeywanada, Swanand Hardikar, Levon Halabelian, Noah Smith, Jiameng Dan, Dalia Barsyte-Lovejoy, Shenfeng Qiu, Yi Xing, Yanzhong Yang
Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing. Nature communications 15 (1) (2024)
Aliakbar Khalili Yazdi, Sumera Perveen, Cheng Dong, Xiaosheng Song, Aiping Dong, Magdalena M Szewczyk, Matthew F Calabrese, Agustin Casimiro-Garcia, Subramanyam Chakrapani, Matthew S Dowling, Emel Ficici, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Grzegorz J Skrzypek, Tuan P Tran, Matthew D Troutman, Feng Wang, Jennifer A Young, Jinrong Min, Dalia Barsyte-Lovejoy, Peter J Brown, Vijayaratnam Santhakumar, Cheryl H Arrowsmith, Masoud Vedadi, Dafydd R Owen
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex. RSC medicinal chemistry 15 (3) (2024)
Germanna Lima Righetto, Yanting Yin, David M Duda, Victoria Vu, Magdalena M Szewczyk, Hong Zeng, Yanjun Li, Peter Loppnau, Tony Mei, Yen-Yen Li, Alma Seitova, Aaron N Patrick, Jean-Francois Brazeau, Charu Chaudhry, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Levon Halabelian
Probing the CRL4 DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons. PNAS nexus 3 (4) (2024)
Dominic D G Owens, Matthew E R Maitland, Aliakbar Khalili Yazdi, Xiaosheng Song, Viviane Reber, Martin Peter Schwalm, Raquel Arminda Carvalho Machado, Nicolas Bauer, Xu Wang, Magdalena M Szewczyk, Cheng Dong, Aiping Dong, Peter Loppnau, Matthew F Calabrese, Matthew S Dowling, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Chakrapani Subramanyam, Feng Wang, Ella C Adamson, Matthieu Schapira, Matthias Gstaiger, Stefan Knapp, Masoud Vedadi, Jinrong Min, Gilles A Lajoie, Dalia Barsyte-Lovejoy, Dafydd R Owen, Caroline Schild-Poulter, Cheryl H Arrowsmith
A chemical probe to modulate human GID4 Pro/N-degron interactions. Nature chemical biology (2024)
David Y Nie, John R Tabor, Jianping Li, Maria Kutera, Jonathan St-Germain, Ronan P Hanley, Esther Wolf, Ethan Paulakonis, Tristan M G Kenney, Shili Duan, Suman Shrestha, Dominic D G Owens, Matthew E R Maitland, Ailing Pon, Magdalena Szewczyk, Anthony Joseph Lamberto, Michael Menes, Fengling Li, Linda Z Penn, Dalia Barsyte-Lovejoy, Nicholas G Brown, Anthony M Barsotti, Andrew W Stamford, Jon L Collins, Derek J Wilson, Brian Raught, Jonathan D Licht, Lindsey I James, Cheryl H Arrowsmith
Recruitment of FBXO22 for targeted degradation of NSD2. Nature chemical biology (2024)
Lei Shen, Xiaokuang Ma, Yuanyuan Wang, Zhihao Wang, Yi Zhang, Hoang Quoc Hai Pham, Xiaoqun Tao, Yuehua Cui, Jing Wei, Dimitri Lin, Tharindumala Abeywanada, Swanand Hardikar, Levon Halabelian, Noah Smith, Jiameng Dan, Dalia Barsyte-Lovejoy, Shenfeng Qiu, Yi Xing, Yanzhong Yang
Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing. Nature communications 15 (1) (2024)
David Y Nie, John R Tabor, Jianping Li, Maria Kutera, Jonathan St-Germain, Ronan P Hanley, Esther Wolf, Ethan Paulakonis, Tristan M G Kenney, Shili Duan, Suman Shrestha, Dominic D G Owens, Matthew E R Maitland, Ailing Pon, Magdalena Szewczyk, Anthony Joseph Lamberto, Michael Menes, Fengling Li, Linda Z Penn, Dalia Barsyte-Lovejoy, Nicholas G Brown, Anthony M Barsotti, Andrew W Stamford, Jon L Collins, Derek J Wilson, Brian Raught, Jonathan D Licht, Lindsey I James, Cheryl H Arrowsmith
Recruitment of FBXO22 for targeted degradation of NSD2. Nature chemical biology (2024)
Aliakbar Khalili Yazdi, Sumera Perveen, Cheng Dong, Xiaosheng Song, Aiping Dong, Magdalena M Szewczyk, Matthew F Calabrese, Agustin Casimiro-Garcia, Subramanyam Chakrapani, Matthew S Dowling, Emel Ficici, Jisun Lee, Justin I Montgomery, Thomas N O'Connell, Grzegorz J Skrzypek, Tuan P Tran, Matthew D Troutman, Feng Wang, Jennifer A Young, Jinrong Min, Dalia Barsyte-Lovejoy, Peter J Brown, Vijayaratnam Santhakumar, Cheryl H Arrowsmith, Masoud Vedadi, Dafydd R Owen
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex. RSC medicinal chemistry 15 (3) (2024)
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Anne E Carpenter, Jonathan H Shrimp, Evelyne Lima-Fernandes, Mathias J Wawer, Lawrence P W Chung, Ayushi Agrawal, Mary O'Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew E Cuellar, Philip A Cole, Jordan L Meier, Tim Thomas, Jonathan B Baell, Peter J Brown, Michael A Walters, Paul A Clemons, Stuart L Schreiber, Bridget K Wagner
Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature communications 14 (1) (2023)
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Anne E Carpenter, Jonathan H Shrimp, Evelyne Lima-Fernandes, Mathias J Wawer, Lawrence P W Chung, Ayushi Agrawal, Mary O'Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew E Cuellar, Philip A Cole, Jordan L Meier, Tim Thomas, Jonathan B Baell, Peter J Brown, Michael A Walters, Paul A Clemons, Stuart L Schreiber, Bridget K Wagner
Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature communications 14 (1) (2023)
Serah W Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Communications biology 6 (1) (2023)
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Anne E Carpenter, Jonathan H Shrimp, Evelyne Lima-Fernandes, Mathias J Wawer, Lawrence P W Chung, Ayushi Agrawal, Mary O'Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew E Cuellar, Philip A Cole, Jordan L Meier, Tim Thomas, Jonathan B Baell, Peter J Brown, Michael A Walters, Paul A Clemons, Stuart L Schreiber, Bridget K Wagner
Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature communications 14 (1) (2023)
Serah W Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Communications biology 6 (1) (2023)
Serah W Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Communications biology 6 (1) (2023)
Serah W Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Communications biology 6 (1) (2023)
Qin Wu, David Y Nie, Wail Ba-Alawi, YiShuai Ji, ZiWen Zhang, Jennifer Cruickshank, Jillian Haight, Felipe E Ciamponi, Jocelyn Chen, Shili Duan, Yudao Shen, Jing Liu, Sajid A Marhon, Parinaz Mehdipour, Magdalena M Szewczyk, Nergiz Dogan-Artun, WenJun Chen, Lan Xin Zhang, Genevieve Deblois, Panagiotis Prinos, Katlin B Massirer, Dalia Barsyte-Lovejoy, Jian Jin, Daniel D De Carvalho, Benjamin Haibe-Kains, XiaoJia Wang, David W Cescon, Mathieu Lupien, Cheryl H Arrowsmith
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer. Nature chemical biology 18 (8) (2022)
Patty Sachamitr, Jolene Caifeng Ho, Felipe E Ciamponi, Wail Ba-Alawi, Fiona J Coutinho, Paul Guilhamon, Michelle M Kushida, Florence M G Cavalli, Lilian Lee, Naghmeh Rastegar, Victoria Vu, Maria Sánchez-Osuna, Jasmin Coulombe-Huntington, Evgeny Kanshin, Heather Whetstone, Mathieu Durand, Philippe Thibault, Kirsten Hart, Maria Mangos, Joseph Veyhl, Wenjun Chen, Nhat Tran, Bang-Chi Duong, Ahmed M Aman, Xinghui Che, Xiaoyang Lan, Owen Whitley, Olga Zaslaver, Dalia Barsyte-Lovejoy, Laura M Richards, Ian J Restall, Amy A Caudy, Hannes L Röst, Zahid Quyoom Bonday, Mark Bernstein, Sunit Das, Michael D Cusimano, Julian Spears, Gary D Baider, Trevor J Pugh, Mike Tyers, Mathieu Lupien, Benjamin Haibe-Kains, H Artee Luchman, Samuel Weiss, Katlin B Massirer, Panagiotis Prinos, Cheryl H Arrowsmith, Peter B Dirks
PRMT5 inhibition disrupts splicing and stemness in glioblastoma. Nature communications 12 (1) (2021)
David Dilworth, Ronan P Hanley, Renato Ferreira de Freitas, Abdellah Allali-Hassani, Mengqi Zhou, Naimee Mehta, Matthew R Marunde, Suzanne Ackloo, Raquel Arminda Carvalho Machado, Aliakbar Khalili Yazdi, Dominic D G Owens, Victoria Vu, David Y Nie, Mona Alqazzaz, Edyta Marcon, Fengling Li, Irene Chau, Albina Bolotokova, Su Qin, Ming Lei, Yanli Liu, Magdalena M Szewczyk, Aiping Dong, Sina Kazemzadeh, Tigran Abramyan, Irina K Popova, Nathan W Hall, Matthew J Meiners, Marcus A Cheek, Elisa Gibson, Dmitri B Kireev, Jack F Greenblatt, Michael-Christopher Keogh, Jinrong Min, Peter J Brown, Masoud Vedadi, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy, Lindsey I James, Matthieu Schapira
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization. Nature chemical biology (2021)
Levon Halabelian, Dalia Barsyte-Lovejoy
Structure and Function of Protein Arginine Methyltransferase PRMT7. Life (Basel, Switzerland) 11 (8) (2021)
Qin Wu, Matthieu Schapira, Cheryl H Arrowsmith, Dalia Barsyte-Lovejoy
Protein arginine methylation: from enigmatic functions to therapeutic targeting. Nature reviews. Drug discovery 20 (7) (2021)
Magdalena M Szewczyk, Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian, Suzanne Ackloo, Amber L Couzens, Mohammad Eram, David Dilworth, Hideto Fukushi, Rachel Harding, Carlo C Dela Seña, Tsukasa Sugo, Kozo Hayashi, David A McLeod, Carlos Zepeda, Ahmed Aman, Maria Sánchez-Osuna, Éric Bonneil, Shinji Takagi, Rima Al-Awar, Mike Tyers, Stephane Richard, Masayuki Takizawa, Anne-Claude Gingras, Cheryl H Arrowsmith, Masoud Vedadi, Peter J Brown, Hiroshi Nara, Dalia Barsyte-Lovejoy
Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nature communications 11 (1) (2020)
Magdalena M Szewczyk, Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian, Suzanne Ackloo, Amber L Couzens, Mohammad Eram, David Dilworth, Hideto Fukushi, Rachel Harding, Carlo C Dela Seña, Tsukasa Sugo, Kozo Hayashi, David A McLeod, Carlos Zepeda, Ahmed Aman, Maria Sánchez-Osuna, Éric Bonneil, Shinji Takagi, Rima Al-Awar, Mike Tyers, Stephane Richard, Masayuki Takizawa, Anne-Claude Gingras, Cheryl H Arrowsmith, Masoud Vedadi, Peter J Brown, Hiroshi Nara, Dalia Barsyte-Lovejoy
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nature communications 11 (1) (2020)
Sebastian Scheer, Suzanne Ackloo, Tiago S Medina, Matthieu Schapira, Fengling Li, Jennifer A Ward, Andrew M Lewis, Jeffrey P Northrop, Paul L Richardson, Husnu Ümit Kaniskan, Yudao Shen, Jing Liu, David Smil, David A McLeod, Carlos A Zepeda-Velazquez, Minkui Luo, Jian Jin, Dalia Barsyte-Lovejoy, Kilian V M Huber, Daniel D De Carvalho, Masoud Vedadi, Colby Zaph, Peter J Brown, Cheryl H Arrowsmith
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nature communications 10 (1) (2019)
Jark Böttcher, David Dilworth, Ulrich Reiser, Ralph A Neumüller, Michael Schleicher, Mark Petronczki, Markus Zeeb, Nikolai Mischerikow, Abdellah Allali-Hassani, Magdalena M Szewczyk, Fengling Li, Steven Kennedy, Masoud Vedadi, Dalia Barsyte-Lovejoy, Peter J Brown, Kilian V M Huber, Catherine M Rogers, Carrow I Wells, Oleg Fedorov, Klaus Rumpel, Andreas Zoephel, Moriz Mayer, Tobias Wunberg, Dietrich Böse, Stephan Zahn, Heribert Arnhof, Helmut Berger, Christoph Reiser, Alexandra Hörmann, Teresa Krammer, Maja Corcokovic, Bernadette Sharps, Sandra Winkler, Daniela Häring, Xiao-Ling Cockcroft, Julian E Fuchs, Barbara Müllauer, Alexander Weiss-Puxbaum, Thomas Gerstberger, Guido Boehmelt, Christopher R Vakoc, Cheryl H Arrowsmith, Mark Pearson, Darryl B McConnell
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nature chemical biology 15 (8) (2019)
Abdellah Allali-Hassani, Magdalena M Szewczyk, Danton Ivanochko, Shawna L Organ, Jabez Bok, Jessica Sook Yuin Ho, Florence P H Gay, Fengling Li, Levi Blazer, Mohammad S Eram, Levon Halabelian, David Dilworth, Genna M Luciani, Evelyne Lima-Fernandes, Qin Wu, Peter Loppnau, Nathan Palmer, S Zakiah A Talib, Peter J Brown, Matthieu Schapira, Philipp Kaldis, Ronan C O'Hagan, Ernesto Guccione, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, John M Sanders, Solomon D Kattar, David Jonathan Bennett, Benjamin Nicholson, Masoud Vedadi
Discovery of a chemical probe for PRDM9. Nature communications 10 (1) (2019)
Evelyne Lima-Fernandes, Alex Murison, Tiago da Silva Medina, Yadong Wang, Anqi Ma, Cherry Leung, Genna M Luciani, Jennifer Haynes, Aaron Pollett, Constanze Zeller, Shili Duan, Antonija Kreso, Dalia Barsyte-Lovejoy, Bradly G Wouters, Jian Jin, Daniel D De Carvalho, Mathieu Lupien, Cheryl H Arrowsmith, Catherine A O'Brien
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells. Nature communications 10 (1) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Dalia Barsyte-Lovejoy