Philip E Thompson (Philip Thompson)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 29

Top Topics

Multiple Myeloma

Molecular Dynamics Simulations

Multidrug Resistant

Acinetobacter Baumannii

Top Venues

Journal of medicinal chemistry

Antibiotics (Basel, Switzerland)

ACS chemical biology

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Wenxiao K Yue, Tianxia Zhang, Rekha Shandre Mugan, Nicholas Barlow, David K Chalmers, Colin W Pouton, Philip E Thompson
Targeting Melanocortin Receptors Using S N Ar-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates. Journal of medicinal chemistry 66 (5) (2023)
Mengyao Li, Mohammad A K Azad, Philip E Thompson, Kade D Roberts, Xukai Jiang, Yan Zhu, Jian Li
Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells. Antibiotics (Basel, Switzerland) 12 (2) (2023)
Wenxiao K Yue, Tianxia Zhang, Rekha Shandre Mugan, Nicholas Barlow, David K Chalmers, Colin W Pouton, Philip E Thompson
Targeting Melanocortin Receptors Using S N Ar-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates. Journal of medicinal chemistry 66 (5) (2023)
Nitin A Patil, Wendong Ma, Xukai Jiang, Xiaoji He, Heidi H Yu, Hasini Wickremasinghe, Jiping Wang, Philip E Thompson, Xukai Jiang, Kade D Roberts, Hsin-Hui Shen
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity. Journal of medicinal chemistry (2023)
Danielle H Oh, Xiao Ma, Simon J Hogg, Jackson He, Conor Kearney, Daniella Brasacchio, Olivia Susanto, Belinda Maher, Ian G Jennings, Andrea Newbold, Peter Fraser, Emily Gruber, Lev M Kats, Gareth P Gregory, Ricky W Johnstone, Philip E Thompson, Jake Shortt
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma. Proceedings of the National Academy of Sciences of the United States of America 120 (36) (2023)
Wenxiao K Yue, Tianxia Zhang, Rekha Shandre Mugan, Nicholas Barlow, David K Chalmers, Colin W Pouton, Philip E Thompson
Targeting Melanocortin Receptors Using S N Ar-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates. Journal of medicinal chemistry 66 (5) (2023)
Wenxiao K Yue, Tianxia Zhang, Rekha Shandre Mugan, Nicholas Barlow, David K Chalmers, Colin W Pouton, Philip E Thompson
Targeting Melanocortin Receptors Using S N Ar-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates. Journal of medicinal chemistry (2023)
Mengyao Li, Mohammad A K Azad, Philip E Thompson, Kade D Roberts, Xukai Jiang, Yan Zhu, Jian Li
Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells. Antibiotics (Basel, Switzerland) 12 (2) (2023)
Nitin A Patil, Wendong Ma, Xukai Jiang, Xiaoji He, Heidi H Yu, Hasini Wickremasinghe, Jiping Wang, Philip E Thompson, Xukai Jiang, Kade D Roberts, Hsin-Hui Shen
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity. Journal of medicinal chemistry 66 (4) (2023)
Xukai Jiang, Nitin A Patil, Yuwen Xu, Hasini Wickremasinghe, Qi Tony Zhou, Fanfan Zhou, Philip E Thompson, Lushan Wang, Min Xiao, Kade D Roberts, Xukai Jiang, Hsin-Hui Shen
Structure-Interaction Relationship of Polymyxins with Lung Surfactant. Journal of medicinal chemistry (2023)
Baolong Pan, Harshini Weerasinghe, Aysha Sezmis, Michael J McDonald, Ana Traven, Philip E Thompson, Claudia Simm
Leveraging the MMV Pathogen Box to Engineer an Antifungal Compound with Improved Efficacy and Selectivity against Candida auris . ACS infectious diseases (2023)
Nitin A Patil, Wendong Ma, Xukai Jiang, Xiaoji He, Heidi H Yu, Hasini Wickremasinghe, Jiping Wang, Philip E Thompson, Xukai Jiang, Kade D Roberts, Hsin-Hui Shen
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity. Journal of medicinal chemistry 66 (4) (2023)
Alicia Corlett, Jo-Anne Pinson, Marwa N Rahimi, Jessica Van Zuylekom, Carleen Cullinane, Benjamin Blyth, Philip E Thompson, Craig A Hutton, Peter D Roselt, Mohammad B Haskali
Development of Highly Potent Clinical Candidates for Theranostic Applications against Cholecystokinin-2 Receptor Positive Cancers. Journal of medicinal chemistry (2023)
Mengyao Li, Mohammad A K Azad, Philip E Thompson, Kade D Roberts, Xukai Jiang, Yan Zhu, Jian Li
Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells. Antibiotics (Basel, Switzerland) 12 (2) (2023)
Nitin A Patil, Wendong Ma, Xukai Jiang, Xiaoji He, Heidi H Yu, Hasini Wickremasinghe, Jiping Wang, Philip E Thompson, Xukai Jiang, Kade D Roberts, Hsin-Hui Shen
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity. Journal of medicinal chemistry 66 (4) (2023)
Desmarini Desmarini, Daniel Truong, Lorna Wilkinson-White, Chandrika Desphande, Mario Torrado, Joel P Mackay, Jacqueline M Matthews, Tania C Sorrell, Sophie Lev, Philip E Thompson, Julianne Teresa Djordjevic
TNP Analogues Inhibit the Virulence Promoting IP<sub>3-4</sub> Kinase Arg1 in the Fungal Pathogen <i>Cryptococcus neoformans</i>. Biomolecules 12 (10) (2022)
Kade D Roberts, Yan Zhu, Mohammad A K Azad, Mei-Ling Han, Jiping Wang, Lynn Wang, Heidi H Yu, Andrew S Horne, Jo-Anne Pinson, David Rudd, Nicolas Hans Voelcker, Nitin A Patil, Jinxin Zhao, Xukai Jiang, Jing Lu, Ke Chen, Olga Lomovskaya, Scott J Hecker, Philip E Thompson, Roger L Nation, Michael N Dudley, David C Griffith, Xukai Jiang, Hsin-Hui Shen
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens. Nature communications 13 (1) (2022)
Billy J Williams-Noonan, Melissa N Speer, Tu C Le, Maiada M Sadek, Philip E Thompson, Raymond S Norton, Elizabeth Yuriev, Nicholas Barlow, David K Chalmers, Irene Yarovsky
Membrane Permeating Macrocycles: Design Guidelines from Machine Learning. Journal of chemical information and modeling 62 (19) (2022)
Matteo Costacurta, Jackson He, Philip E Thompson, Jake Shortt
Molecular Mechanisms of Cereblon-Interacting Small Molecules in Multiple Myeloma Therapy. Journal of personalized medicine 11 (11) (2021)
Xukai Jiang, Nitin A Patil, Mohammad A K Azad, Hasini Wickremasinghe, Heidi Yu, Jinxin Zhao, Xinru Zhang, Mengyao Li, Bin Gong, Lin Wan, Wendong Ma, Philip E Thompson, Kai Yang, Bing Yuan, Falk Schreiber, Lushan Wang, Tony Velkov, Kade D Roberts, Hsin-Hui Shen
A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii. Chemical science 12 (36) (2021)
Maria V Selvadurai, Mitchell J Moon, Simon J Mountford, Xiao Ma, Zhaohua Zheng, Ian G Jennings, Natasha M Setiabakti, Rizani P Iman, Rose J Brazilek, Nurul Aisha Z Abidin, Gaëtan Chicanne, Sonia Severin, Alyce J Nicholls, Connie H Y Wong, Jean-Yves Rinckel, Anita Eckly, Christian Gachet, Warwick S Nesbitt, Philip E Thompson, Justin R Hamilton
Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation. Science translational medicine 12 (553) (2021)
Alicia Corlett, Marc-Antoine Sani, Jessica Van Zuylekom, Ching-Seng Ang, Elisabeth von Guggenberg, Carleen Cullinane, Benjamin Blyth, Rodney J Hicks, Peter D Roselt, Philip E Thompson, Craig A Hutton, Mohammad B Haskali
A New Turn in Peptide-Based Imaging Agents: Foldamers Afford Improved Theranostics Targeting Cholecystokinin-2 Receptor-Positive Cancer. Journal of medicinal chemistry 64 (8) (2021)
Nicholas Barlow, David K Chalmers, Billy J Williams-Noonan, Philip E Thompson, Raymond S Norton
Improving Membrane Permeation in the Beyond Rule-of-Five Space by Using Prodrugs to Mask Hydrogen Bond Donors. ACS chemical biology 15 (8) (2020)
Xukai Jiang, Shuo Zhang, Mohammad A K Azad, Kade D Roberts, Lin Wan, Bin Gong, Kai Yang, Bing Yuan, Hemayet Uddin, Jingliang Li, Philip E Thompson, Tony Velkov, Jing Fu, Lushan Wang, Hsin-Hui Shen
Structure-Interaction Relationship of Polymyxins with the Membrane of Human Kidney Proximal Tubular Cells. ACS infectious diseases 6 (8) (2020)
Simon J Mountford, Bethany M Anderson, Bangyan Xu, Elean S V Tay, Monika Szabo, My-Linh Hoang, Jiayin Diao, Luigi Aurelio, Rhiannon I Campden, Erik Lindström, Erica K Sloan, Robin M Yates, Nigel W Bunnett, Philip E Thompson, Laura E Edgington-Mitchell
Application of a Sulfoxonium Ylide Electrophile to Generate Cathepsin X-Selective Activity-Based Probes. ACS chemical biology 15 (3) (2020)
Rachel R Richardson, Marleen Groenen, Mengjie Liu, Simon J Mountford, Stephen J Briddon, Nicholas D Holliday, Philip E Thompson
Heterodimeric Analogues of the Potent Y1R Antagonist 1229U91, Lacking One of the Pharmacophoric C-Terminal Structures, Retain Potent Y1R Affinity and Show Improved Selectivity over Y4R. Journal of medicinal chemistry 63 (10) (2020)
Nicholas Barlow, Sudarsana Reddy Vanga, Jonas Sävmarker, Anja Sandström, Peta Burns, Anders Hallberg, Johan Åqvist, Hugo Gutiérrez-de-Terán, Mathias Hallberg, Mats Larhed, Siew Yeen Chai, Philip E Thompson
Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP). RSC medicinal chemistry 11 (2) (2020)
Susan E Northfield, Jerome Wielens, Stephen J Headey, Billy J Williams-Noonan, Mark Mulcair, Martin G Scanlon, Michael W Parker, Philip E Thompson, David K Chalmers
Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV-1 Integrase. ChemMedChem 13 (15) (2018)
Mitchell R Silk, Biswaranjan Mohanty, Joanne B Sampson, Martin J Scanlon, Philip E Thompson, David K Chalmers
Controlled Construction of Cyclic d / l Peptide Nanorods. Angewandte Chemie (International ed. in English) 58 (2) (2018)