Martin J Scanlon

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 22

Top Venues

ChemMedChem

The Journal of biological chemistry

RSC medicinal chemistry

ACS medicinal chemistry letters

Monash Institute of Pharmaceutical Sciences

University of Nottingham (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Monash Institute of Pharmaceutical Sciences

Australia

Professor :: Medicinal Chemistry

Biomolecular Research Institute

Australia

Postdoctoral Scientist :: Structural Biology

Education History

University of Nottingham

United Kingdom

PHD

Publications

Bradley C Doak, Rebecca L Whitehouse, Kieran Rimmer, Martin Williams, Begoña Heras, Sofia Caria, Olga Ilyichova, Mansha Vazirani, Biswaranjan Mohanty, Jason B Harper, Martin J Scanlon, Jamie S Simpson
Fluoromethylketone-Fragment Conjugates Designed as Covalent Modifiers of EcDsbA are Atypical Substrates. ChemMedChem (2024)
Bradley C Doak, Rebecca L Whitehouse, Kieran Rimmer, Martin Williams, Begoña Heras, Sofia Caria, Olga Ilyichova, Mansha Vazirani, Biswaranjan Mohanty, Jason B Harper, Martin J Scanlon, Jamie S Simpson
Fluoromethylketone-Fragment Conjugates Designed as Covalent Modifiers of EcDsbA are Atypical Substrates. ChemMedChem 19 (16) (2024)
Michelle Q Phan, Indu R Chandrashekaran, Naureen Akhtar, Evgenia Konstantinidou, Shane M Devine, Bradley C Doak, Thomas Nebl, Darren John Creek, Martin J Scanlon, Raymond S Norton
Multiplexed Native Mass Spectrometry Determination of Ligand Selectivity for Fatty Acid-Binding Proteins. ACS medicinal chemistry letters 15 (7) (2024)
Michelle Q Phan, Indu R Chandrashekaran, Naureen Akhtar, Evgenia Konstantinidou, Shane M Devine, Bradley C Doak, Thomas Nebl, Darren John Creek, Martin J Scanlon, Raymond S Norton
Multiplexed Native Mass Spectrometry Determination of Ligand Selectivity for Fatty Acid-Binding Proteins. ACS medicinal chemistry letters 15 (7) (2024)
Luke A Adams, Lorna E Wilkinson-White, Menachem J Gunzburg, Stephen J Headey, Biswaranjan Mohanty, Martin J Scanlon, Ben Capuano, Joel P Mackay, Bradley C Doak
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain. Journal of medicinal chemistry (2023)
Rebecca L Whitehouse, Wesam S Alwan, Olga V Ilyichova, Ashley J Taylor, Indu R Chandrashekaran, Biswaranjan Mohanty, Bradley C Doak, Martin J Scanlon
Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores. RSC medicinal chemistry 14 (1) (2022)
Geqing Wang, Biswaranjan Mohanty, Martin L Williams, Bradley C Doak, Rabeb Dhouib, Makrina Totsika, Róisín M McMahon, Gaurav Sharma, Dan Zheng, Matthew R Bentley, Yanni Ka-Yan Chin, James Horne, David K Chalmers, Begoña Heras, Martin J Scanlon
Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials. ChemMedChem 17 (6) (2022)
Guillaume A Petit, Biswaranjan Mohanty, Róisín M McMahon, Stefan Nebl, David Hugh Hilko, Karyn L Wilde, Martin J Scanlon, Jennifer H Martin, Maria A Halili
Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta crystallographica. Section D, Structural biology 78 (Pt 1) (2022)
Rebecca L Whitehouse, Wesam S Alwan, Olga V Ilyichova, Ashley J Taylor, Indu R Chandrashekaran, Biswaranjan Mohanty, Bradley C Doak, Martin J Scanlon
Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores. RSC medicinal chemistry 14 (1) (2022)
Matthew R Bentley, Olga V Ilyichova, Geqing Wang, Martin L Williams, Gaurav Sharma, Wesam S Alwan, Rebecca L Whitehouse, Biswaranjan Mohanty, Peter J Scammells, Begoña Heras, Jennifer L Martin, Makrina Totsika, Ben Capuano, Bradley C Doak, Martin J Scanlon
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX). Journal of medicinal chemistry 63 (13) (2020)
Stefan Nebl, Wesam S Alwan, Martin L Williams, Gaurav Sharma, Ashley Taylor, Bradley C Doak, Karyn L Wilde, Róisín M McMahon, Maria A Halili, Jennifer L Martin, Ben Capuano, R Bryn Fenwick, Biswaranjan Mohanty, Martin J Scanlon
NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide-dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei. Journal of biomolecular NMR 74 (10-11) (2020)
Luke F Duncan, Geqing Wang, Olga V Ilyichova, Martin J Scanlon, Begoña Heras, Belinda M Abbott
The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors. Molecules (Basel, Switzerland) 24 (20) (2019)
Mansura Akter, Nyssa Drinkwater, Shane M Devine, Simon C Drew, Bankala Krishnarjuna, Cael O Debono, Geqing Wang, Martin J Scanlon, Peter J Scammells, Sheena McGowan, Christopher A MacRaild, Raymond S Norton
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe. ChemMedChem 14 (5) (2019)
Roxanne P Smith, Biswaranjan Mohanty, Shakeel Mowlaboccus, Jason J Paxman, Martin L Williams, Stephen J Headey, Geqing Wang, Pramod Subedi, Bradley C Doak, Charlene M Kahler, Martin J Scanlon, Begoña Heras
Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens. The Journal of biological chemistry 293 (43) (2018)
Roxanne P Smith, Andrew E Whitten, Jason J Paxman, Charlene M Kahler, Martin J Scanlon, Begoña Heras
Production, biophysical characterization and initial crystallization studies of the N- and C-terminal domains of DsbD, an essential enzyme in Neisseria meningitidis. Acta crystallographica. Section F, Structural biology communications 74 (Pt 1) (2018)
Dane D Jensen, TinaMarie Lieu, Michelle L Halls, Nicholas A Veldhuis, Wendy L Imlach, Quynh N Mai, Daniel P Poole, Tim Quach, Luigi Aurelio, Joshua W Conner, Carmen Klein Herenbrink, Nicholas Barlow, Jamie S Simpson, Martin J Scanlon, Bimbil Graham, Adam McCluskey, Phillip J Robinson, Virginie Escriou, Romina Nassini, Serena Materazzi, Pierangelo Geppetti, Gareth A Hicks, Macdonald J Christie, Christopher J H Porter, Meritxell Canals, Nigel W Bunnett
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief. Science translational medicine 9 (392) (2018)
Rahul Patil, Biswaranjan Mohanty, Bonan Liu, Indu R Chandrashekaran, Stephen J Headey, Martin L Williams, Craig S Clements, Olga Ilyichova, Bradley C Doak, Patrick Genissel, Richard J Weaver, Laurent Vuillard, Michelle L Halls, Christopher J H Porter, Martin J Scanlon
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists. The Journal of biological chemistry 294 (10) (2018)
Zorik Chilingaryan, Stephen J Headey, Allen T Y Lo, Zhi-Qiang Xu, Gottfried Otting, Nicholas E Dixon, Martin J Scanlon, Aaron J Oakley
Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction. Antibiotics (Basel, Switzerland) 7 (1) (2018)
Mitchell R Silk, Biswaranjan Mohanty, Joanne B Sampson, Martin J Scanlon, Philip E Thompson, David K Chalmers
Controlled Construction of Cyclic d / l Peptide Nanorods. Angewandte Chemie (International ed. in English) 58 (2) (2018)
Yijun Pan, Jennifer L Short, Kwok H C Choy, Annie X Zeng, Philip J Marriott, Yuji Owada, Martin J Scanlon, Christopher J H Porter, Joseph A Nicolazzo
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function. The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (46) (2017)
Biswaranjan Mohanty, Kieran Rimmer, Róisín M McMahon, Stephen J Headey, Mansha Vazirani, Stephen R Shouldice, Mathieu Coinçon, Stephanie Tay, Craig J Morton, Jamie S Simpson, Jennifer L Martin, Martin J Scanlon
Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PloS one 12 (3) (2017)
Roxanne P Smith, Biswaranjan Mohanty, Martin L Williams, Martin J Scanlon, Begoña Heras
HN, N, Cα and Cβ assignments of the two periplasmic domains of Neisseria meningitidis DsbD. Biomolecular NMR assignments 11 (2) (2017)

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Publication Activity (10 Years)

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Martin J Scanlon