Martin Edward Kampmann (Martin Kampmann)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 65

Top Topics

Multiple Myeloma

Structural Basis

Top Venues

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Nature reviews. Neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Femke M Feringa, Sascha J Koppes-den Hertog, Lian Wang, Rico J E Derks, Iris Kruijff, Lena Erlebach, Jorin Heijneman, Ricardo Miramontes, Nadine Pömpner, Niek Blomberg, Damien Olivier-Jimenez, Lill Eva Johansen, Alexander J Cammack, Ashling Giblin, Christina E Toomey, Indigo V L Rose, Hebao Yuan, Michael Ward, Adrian M Isaacs, Martin Edward Kampmann, Deborah Kronenberg-Versteeg, Tammaryn Lashley, Leslie M Thompson, Alessandro Ori, Yassene Mohammed, Martin A Giera, Rik van der Kant
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4. bioRxiv : the preprint server for biology (2024)
Kevin M Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Kevin M Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Nawei Sun, Noam B Teyssier, Belinda Wang, Sam Drake, Meghan Seyler, Yefim Zaltsman, Amanda Everitt, Nia Teerikorpi, Helen Rankin Willsey, Hani Goodarzi, Ruilin Tian, Martin Edward Kampmann, A Jeremy Willsey
Autism genes converge on microtubule biology and RNA-binding proteins during excitatory neurogenesis. bioRxiv : the preprint server for biology (2024)
Martin Edward Kampmann
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases. Nature reviews. Neuroscience 25 (5) (2024)
Martin Edward Kampmann
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases. Nature reviews. Neuroscience 25 (5) (2024)
Femke M Feringa, Sascha J Koppes-den Hertog, Lian Wang, Rico J E Derks, Iris Kruijff, Lena Erlebach, Jorin Heijneman, Ricardo Miramontes, Nadine Pömpner, Niek Blomberg, Damien Olivier-Jimenez, Lill Eva Johansen, Alexander J Cammack, Ashling Giblin, Christina E Toomey, Indigo V L Rose, Hebao Yuan, Michael Ward, Adrian M Isaacs, Martin Edward Kampmann, Deborah Kronenberg-Versteeg, Tammaryn Lashley, Leslie M Thompson, Alessandro Ori, Yassene Mohammed, Martin A Giera, Rik van der Kant
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4. bioRxiv : the preprint server for biology (2024)
Martin Edward Kampmann
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases. Nature reviews. Neuroscience 25 (5) (2024)
Martin Edward Kampmann
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases. Nature reviews. Neuroscience 25 (5) (2024)
Gregory A Mohl, Gary Dixon, Emily Marzette, Justin McKetney, Avi J Samelson, Carlota Pereda Serras, Julianne Jin, Andrew Li, Steven C Boggess, Danielle L Swaney, Martin Edward Kampmann
The disease-causing tau V337M mutation induces tau hypophosphorylation and perturbs axon morphology pathways. bioRxiv : the preprint server for biology (2024)
Brandon Novy, Aleksandra Dagunts, Tatum Weishaar, Emily E Holland, Hayden Adoff, Emily Hutchinson, Monica De Maria, Martin Edward Kampmann, Nikoleta G Tsvetanova, Braden T Lobingier
An engineered trafficking biosensor reveals a role for DNAJC13 in DOR downregulation. Nature chemical biology (2024)
Gregory A Mohl, Gary Dixon, Emily Marzette, Justin McKetney, Avi J Samelson, Carlota Pereda Serras, Julianne Jin, Andrew Li, Steven C Boggess, Danielle L Swaney, Martin Edward Kampmann
The disease-causing tau V337M mutation induces tau hypophosphorylation and perturbs axon morphology pathways. bioRxiv : the preprint server for biology (2024)
Kevin M Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Femke M Feringa, Sascha J Koppes-den Hertog, Lian Wang, Rico J E Derks, Iris Kruijff, Lena Erlebach, Jorin Heijneman, Ricardo Miramontes, Nadine Pömpner, Niek Blomberg, Damien Olivier-Jimenez, Lill Eva Johansen, Alexander J Cammack, Ashling Giblin, Christina E Toomey, Indigo V L Rose, Hebao Yuan, Michael Ward, Adrian M Isaacs, Martin Edward Kampmann, Deborah Kronenberg-Versteeg, Tammaryn Lashley, Leslie M Thompson, Alessandro Ori, Yassene Mohammed, Martin A Giera, Rik van der Kant
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4. bioRxiv : the preprint server for biology (2024)
Kevin M Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Kevin M Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Martin Edward Kampmann
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases. Nature reviews. Neuroscience (2024)
Kevin M Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Jie Yang, Kelsey R Baron, Daniel E Pride, Anette Schneemann, Xiaoyan Guo, Wenqian Chen, Albert S Song, Giovanni Aviles, Martin Edward Kampmann, R Luke Wiseman, Gabriel C Lander
DELE1 oligomerization promotes integrated stress response activation. Nature structural & molecular biology (2023)
Biswarathan Ramani, Indigo V L Rose, Andrew Pan, Ruilin Tian, Keran Ma, Jorge J Palop, Martin Edward Kampmann
Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain. bioRxiv : the preprint server for biology (2023)
Kevin Rose, Tyler Jepson, Sankalp Shukla, Alex Maya-Romero, Martin Edward Kampmann, Ke Xu, James H Hurley
Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes. bioRxiv : the preprint server for biology (2023)
Vedagopuram Sreekanth, Max Jan, Kevin Tianmeng Zhao, Donghyun Lim, Jessie R Davis, Marie McConkey, Veronica Kovalcik, Sam Barkal, Benjamin K Law, James D Fife, Ruilin Tian, Michael E Vinyard, Basheer Becerra, Martin Edward Kampmann, Richard I Sherwood, Luca Pinello, David R Liu, Benjamin L Ebert, Amit Choudhary
A molecular glue approach to control the half-life of CRISPR-based technologies. bioRxiv : the preprint server for biology (2023)
Emmy Li, Camila Benitez, Steven C Boggess, Mark Koontz, Indigo V L Rose, Nina Draeger, Olivia M Teter, Avi J Samelson, Erik M Ullian, Martin Edward Kampmann
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions. bioRxiv : the preprint server for biology (2023)
Emmy Li, Camila Benitez, Steven C Boggess, Mark Koontz, Indigo V L Rose, Nina Draeger, Olivia M Teter, Avi J Samelson, Erik M Ullian, Martin Edward Kampmann
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions. bioRxiv : the preprint server for biology (2023)
Valerie Perea, Kelsey R Baron, Vivian Dolina, Giovanni Aviles, Jessica D Rosarda, Xiaoyan Guo, Martin Edward Kampmann, R Luke Wiseman
Pharmacologic Activation of an Integrated Stress Response Kinase Promotes Mitochondrial Remodeling. bioRxiv : the preprint server for biology (2023)
Emmy Li, Camila Benitez, Steven C Boggess, Mark Koontz, Indigo V L Rose, Nina Draeger, Olivia M Teter, Avi J Samelson, Erik M Ullian, Martin Edward Kampmann
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions. bioRxiv : the preprint server for biology (2023)
Adriano Aguzzi, Martin Edward Kampmann
Neurodegeneration enters the era of functional genomics. Science (New York, N.Y.) 381 (6662) (2023)
Avi J Samelson, Nabeela Ariqat, Justin McKetney, Gita Rohanitazangi, Celeste Parra Bravo, Darrin Goodness, Ruilin Tian, Parker Grosjean, Romany Abskharon, David Eisenberg, Nicholas M Kanaan, Li Gan, Carlo Condello, Danielle L Swaney, Martin Edward Kampmann
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. bioRxiv : the preprint server for biology (2023)
Emmy Li, Camila Benitez, Steven C Boggess, Mark Koontz, Indigo V L Rose, Nina Draeger, Olivia M Teter, Avi J Samelson, Erik M Ullian, Martin Edward Kampmann
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions. bioRxiv : the preprint server for biology (2023)
Celeste Parra Bravo, Alice Maria Giani, Jesus Madero Perez, Zeping Zhao, Avi Samelson, Man Ying Wong, Alessandro Evangelisti, Li Fan, Tatyana Pozner, Maria Mercedes, Pearly Ye, Tark Patel, Allan Yarahmady, Gillian K Carling, Virginia M Y Lee, Manu Sharma, Sue-Ann Mok, Wenjie Luo, Mingrui Zhao, Martin Edward Kampmann, Shiaoching Gong, Li Gan
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. bioRxiv : the preprint server for biology (2023)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Gregory J Krause, Antonio Diaz, Maryam Jafari, Rabia R Khawaja, Esperanza Agullo-Pascual, Olaya Santiago-Fernández, Alicia L Richards, Kuei-Ho Chen, Phillip Dmitriev, Yan Sun, Stephanie K See, Kotb Abdelmohsen, Krystyna Mazan-Mamczarz, Nevan J Krogan, Myriam Gorospe, Danielle L Swaney, Simone Sidoli, Jose Javier Bravo-Cordero, Martin Edward Kampmann, Ana Maria Cuervo
Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion. Aging cell 21 (10) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Robert G Bristow, Joanne Engel, Isuru D Jayasinghe, Martin Edward Kampmann, Owen James Sansom, David M Bryant Editor
Conversations with LGBT+ scientists about visibility, leadership and climbing the career ladder. Journal of cell science 135 (4) (2022)
Avi J Samelson, Quang Dinh Tran, Rémy Robinot, Lucia Carrau, Veronica V Rezelj, Alice Mac Kain, Merissa Chen, Gokul N Ramadoss, Xiaoyan Guo, Shion An Lim, Irene Lui, James K Nuñez, Sarah J Rockwood, Jianhui Wang, Na Liu, Jared Carlson-Stevermer, Jennifer Oki, Travis Maures, Kevin Holden, Jonathan S Weissman, James A Wells, Bruce R Conklin, Benjamin R tenOever, Lisa A Chakrabarti, Marco Vignuzzi, Ruilin Tian, Martin Edward Kampmann
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. Nature cell biology 24 (1) (2022)
Yonatan A Cooper, Noam Teyssier, Nina M Dräger, Qiuyu Guo, Jessica E Davis, Sydney M Sattler, Zhongan Yang, Abdulsamie Patel, Sarah Wu, Sriram Kosuri, Giovanni Coppola, Martin Edward Kampmann, Daniel H Geschwind
Functional regulatory variants implicate distinct transcriptional networks in dementia. Science (New York, N.Y.) 377 (6608) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Hyosung Kim, Kun Leng, Jinhee Park, Alexander G Sorets, Suil Kim, Alena Shostak, Rebecca J Embalabala, Kate Mlouk, Ketaki A Katdare, Indigo V L Rose, Sarah M Sturgeon, Emma H Neal, Yan Ao, Shinong Wang, Michael V Sofroniew, Jonathan M Brunger, Douglas G McMahon, Matthew S Schrag, Martin Edward Kampmann, Ethan S Lippmann
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Nature communications 13 (1) (2022)
Marcus Y Chin, Kean-Hooi Ang, Julia Davies, Carolina Alquezar, Virginia G Garda, Brendan Rooney, Kun Leng, Martin Edward Kampmann, Michelle R Arkin, Aimee W Kao
Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model. ACS chemical neuroscience 13 (10) (2022)
Nina M Dräger, Sydney M Sattler, Cindy Tzu-Ling Huang, Olivia M Teter, Kun Leng, Sayed Hadi Hashemi, Jason Hong, Giovanni Aviles, Claire Dudley Clelland, Lihong Zhan, Joe C Udeochu, Lay Kodama, Andrew B Singleton, Mike A Nalls, Justin Ichida, Michael Emmerson Ward, Faraz Faghri, Li Gan, Martin Edward Kampmann
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states. Nature neuroscience 25 (9) (2022)
Kun Leng, Indigo V L Rose, Hyosung Kim, Wenlong Xia, Wilber Romero-Fernandez, Brendan Rooney, Mark Koontz, Emmy Li, Yan Ao, Shinong Wang, Mitchell Krawczyk, Julia Tcw, Alison Mary Goate, Ye Zhang, Erik M Ullian, Michael V Sofroniew, Stephen P J Fancy, Matthew S Schrag, Ethan S Lippmann, Martin Edward Kampmann
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states. Nature neuroscience 25 (11) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Kun Leng, Martin Edward Kampmann
Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics. Genome medicine 14 (1) (2022)
Ruilin Tian, Anthony Abarientos, Jason Hong, Sayed Hadi Hashemi, Rui Yan, Nina Dräger, Kun Leng, Mike A Nalls, Andrew B Singleton, Ke Xu, Faraz Faghri, Martin Edward Kampmann
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis. Nature neuroscience 24 (7) (2021)
Kun Leng, Emmy Li, Rana A Eser, Antonia Piergies, Rene Sit, Michelle Tan, Norma F Neff, Song Hua Li, Roberta Diehl Rodriguez, Claudia Kimie Suemoto, Renata Elaine Paraizo Leite, Alexander J Ehrenberg, Carlos A Pasqualucci, William W Seeley, Salvatore Spina, Helmut Heinsen, Lea Tenenholz Grinberg, Martin Edward Kampmann
Molecular characterization of selectively vulnerable neurons in Alzheimer's disease. Nature neuroscience 24 (2) (2021)
Maxence Le Vasseur, Jonathan R Friedman, Marco Jost, Jiawei Xu, Justin Yamada, Martin Edward Kampmann, Max A Horlbeck, Michelle R Salemi, Brett S Phinney, Jonathan S Weissman, Jodi Nunnari
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. eLife 10 (2021)
Xiaoyan Guo, Giovanni Aviles, Yi Liu, Ruilin Tian, Bret A Unger, Yu-Hsiu Tony Lin, Arun P Wiita, Ke Xu, M Almira Correia, Martin Edward Kampmann
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature 579 (7799) (2020)
Robert W Newberry, Taylor Arhar, Jean Costello, George C Hartoularos, Alison M Maxwell, Zun Zar Chi Naing, Maureen Pittman, Nishith R Reddy, Daniel M C Schwarz, Douglas R Wassarman, Taia S Wu, Daniel Barrero, Christa Caggiano, Adam Catching, Taylor B Cavazos, Laurel S Estes, Bryan Faust, Elissa A Fink, Miriam A Goldman, Yessica K Gomez, M Grace Gordon, Laura M Gunsalus, Nick Hoppe, Maru Jaime-Garza, Matthew C Johnson, Matthew G Jones, Andrew F Kung, Kyle E Lopez, Jared Lumpe, Calla Martyn, Elizabeth E McCarthy, Lakshmi E Miller-Vedam, Erik J Navarro, Aji Palar, Jenna Pellegrino, Wren Saylor, Christina A Stephens, Jack Strickland, Hayarpi Torosyan, Stephanie A Wankowicz, Daniel R Wong, Garrett Wong, Sy Redding, Eric D Chow, William F DeGrado, Martin Edward Kampmann
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding. ACS chemical biology 15 (8) (2020)
Martin Edward Kampmann
CRISPR-based functional genomics for neurological disease. Nature reviews. Neurology 16 (9) (2020)
Neal K Bennett, Mai K Nguyen, Maxwell A Darch, Hiroki J Nakaoka, Derek Cousineau, Johanna Ten Hoeve, Thomas Glen Graeber, Markus Schuelke, Emin Maltepe, Martin Edward Kampmann, Bryce A Mendelsohn, Jean L Nakamura, Ken Nakamura
Defining the ATPome reveals cross-optimization of metabolic pathways. Nature communications 11 (1) (2020)
Robert W Newberry, Jaime T Leong, Eric D Chow, Martin Edward Kampmann, William F DeGrado
Deep mutational scanning reveals the structural basis for α-synuclein activity. Nature chemical biology 16 (6) (2020)
Jennifer N Rauch, Gabriel Luna, Elmer Guzman, Morgane Audouard, Collin Challis, Youssef E Sibih, Carolina Leshuk, Israel Hernandez, Susanne Wegmann, Bradley T Hyman, Viviana Gradinaru, Martin Edward Kampmann, Kenneth S Kosik
LRP1 is a master regulator of tau uptake and spread. Nature 580 (7803) (2020)
Coralie Poulard, Hye Na Kim, Mimi Fang, Karina Kruth, Celine Gagnieux, Daniel S Gerke, Deepa Bhojwani, Yong-Mi Kim, Martin Edward Kampmann, Michael R Stallcup, Miles A Pufall
Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America 116 (8) (2019)
John J Chen, Diane L Nathaniel, Preethi Raghavan, Maxine Nelson, Ruilin Tian, Eric Tse, Jason Y Hong, Stephanie K See, Sue-Ann Mok, Marco Y Hein, Daniel R Southworth, Lea T Grinberg, Jason E Gestwicki, Manuel D Leonetti, Martin Edward Kampmann
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation. The Journal of biological chemistry 294 (50) (2019)
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F Gendron, Yanwei Wu, Karen Jansen-West, Aliesha D O'Raw, Sarah R Pickles, Mercedes Prudencio, Yari Carlomagno, Mariam A Gachechiladze, Connor Ludwig, Ruilin Tian, Jeannie Chew, Michael A DeTure, Wen-Lang Lin, Jimei Tong, Lillian M Daughrity, Mei Yue, Yuping Song, Jonathan W Andersen, Monica Castanedes Casey, Aishe Kurti, Abhishek Datta, Giovanna Antognetti, Alexander McCampbell, Rosa Rademakers, Björn E Oskarsson, Gourisankar Ghosh, Martin Edward Kampmann, Michael Emmerson Ward, John D Fryer, Christopher D Link, James Shorter, Leonard Petrucelli
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity. Science (New York, N.Y.) 363 (6428) (2019)
Sandra Elizabeth Torres, Ciara M Gallagher, Lars Plate, Meghna Gupta, Christina R Liem, Xiaoyan Guo, Ruilin Tian, Robert M Stroud, Martin Edward Kampmann, Jonathan S Weissman, Peter Walter
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. eLife 8 (2019)
Michael Boettcher, Ruilin Tian, James A Blau, Evan Markegard, Ryan T Wagner, David Wu, Xiulei Mo, Anne Biton, Noah Zaitlen, Haian Fu, Frank McCormick, Martin Edward Kampmann, Michael T McManus
Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nature biotechnology 36 (2) (2018)
Jennifer N Rauch, John J Chen, Alexander W Sorum, Gregory M Miller, Tal Sharf, Stephanie K See, Linda C Hsieh-Wilson, Martin Edward Kampmann, Kenneth S Kosik
Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs). Scientific reports 8 (1) (2018)
Tamas Nagy, Martin Edward Kampmann
CRISPulator: a discrete simulation tool for pooled genetic screens. BMC bioinformatics 18 (1) (2017)
Martin Edward Kampmann
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine. ACS chemical biology 13 (2) (2017)
Karina A Kruth, Mimi Fang, Dawne N Shelton, Ossama Abu-Halawa, Ryan Mahling, Hongxing Yang, Jonathan S Weissman, Mignon L Loh, Markus Müschen, Sarah K Tasian, Michael C Bassik, Martin Edward Kampmann, Miles A Pufall
Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood 129 (22) (2017)
Richard M Deans, David W Morgens, Ayşe Ökesli, Sirika Pillay, Max A Horlbeck, Martin Edward Kampmann, Luke A Gilbert, Amy Li, Roberto Mateo, Mark Smith, Jeffrey S Glenn, Jan E Carette, Chaitan Khosla, Michael C Bassik
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. Nature chemical biology 12 (5) (2016)
Max A Horlbeck, Luke A Gilbert, Jacqueline E Villalta, Britt Adamson, Ryan A Pak, Yuwen Chen, Alexander P Fields, Chong Yon Park, Jacob E Corn, Martin Edward Kampmann, Jonathan S Weissman
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. eLife 5 (2016)
Carmela Sidrauski, Jordan C Tsai, Martin Edward Kampmann, Brian R Hearn, Punitha Vedantham, Priyadarshini Jaishankar, Masaaki Sokabe, Aaron S Mendez, Billy W Newton, Edward L Tang, Erik Verschueren, Jeffrey R Johnson, Nevan J Krogan, Christopher S Fraser, Jonathan S Weissman, Adam R Renslo, Peter Walter
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. eLife 4 (2015)
Diego Acosta-Alvear, Min Y Cho, Thomas Wild, Tonia J Buchholz, Alana G Lerner, Olga Simakova, Jamie Hahn, Neha Korde, Ola Landgren, Irina Maric, Chunaram Choudhary, Peter Walter, Jonathan S Weissman, Martin Edward Kampmann
Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. eLife 4 (2015)