Rita C Guedes

ResearcherID Scopus Author ID Ciência ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 25

Top Topics

Molecular Docking

Multiple Myeloma

Top Venues

International journal of molecular sciences

Molecules (Basel, Switzerland)

Pharmaceuticals (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Rita Manguinhas, Patrícia A Serra, Rita B Soares, Rafael Rosell, Nuno Gil, Nuno G Oliveira, Rita C Guedes
Unveiling Novel ERCC1-XPF Complex Inhibitors: Bridging the Gap from In Silico Exploration to Experimental Design. International journal of molecular sciences 25 (2) (2024)
Rita Manguinhas, Patrícia A Serra, Rita B Soares, Rafael Rosell, Nuno Gil, Nuno G Oliveira, Rita C Guedes
Unveiling Novel ERCC1-XPF Complex Inhibitors: Bridging the Gap from In Silico Exploration to Experimental Design. International journal of molecular sciences 25 (2) (2024)
Tiago Delgado, João Pedro Pais, David Pires, Filipe G A Estrada, Rita C Guedes, Elsa Anes, Luís Constantino
Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold. Pharmaceuticals (Basel, Switzerland) 17 (5) (2024)
Tiago Delgado, João Pedro Pais, David Pires, Filipe G A Estrada, Rita C Guedes, Elsa Anes, Luís Constantino
Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold. Pharmaceuticals (Basel, Switzerland) 17 (5) (2024)
Natália Aniceto, Tânia S Albuquerque, Vasco D B Bonifácio, Rita C Guedes, Nuno Martinho
Using Machine Learning and Molecular Docking to Leverage Urease Inhibition Data for Virtual Screening. International journal of molecular sciences 24 (9) (2023)
Romina A Guedes, Jorge H Grilo, Andreia Neves Carvalho, Pedro M P Fernandes, Ana S Ressurreição, Vanessa Brito, Adriana O Santos, Samuel M Silvestre, Eleonora Gallerani, Maria João Gama, Riccardo Gavioli, Jorge A R Salvador, Rita C Guedes
New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies. Pharmaceuticals (Basel, Switzerland) 16 (8) (2023)
Natália Aniceto, Tânia S Albuquerque, Vasco D B Bonifácio, Rita C Guedes, Nuno Martinho
Using Machine Learning and Molecular Docking to Leverage Urease Inhibition Data for Virtual Screening. International journal of molecular sciences 24 (9) (2023)
Natália Aniceto, Vasco D B Bonifácio, Rita C Guedes, Nuno Martinho
Exploring the Chemical Space of Urease Inhibitors to Extract Meaningful Trends and Drivers of Activity. Journal of chemical information and modeling 62 (15) (2022)
Natália Aniceto, Vanda Marques, Joana D Amaral, Patrícia A Serra, Rui Moreira, Cecília Maria Pereira Rodrigues, Rita C Guedes
Harnessing Protein-Ligand Interaction Fingerprints to Predict New Scaffolds of RIPK1 Inhibitors. Molecules (Basel, Switzerland) 27 (15) (2022)
Catarina Franco, Samina Kausar, Margarida F B Silva, Rita C Guedes, Andre O Falcao, Maria Alexandra Brito
Multi-Targeting Approach in Glioblastoma Using Computer-Assisted Drug Discovery Tools to Overcome the Blood-Brain Barrier and Target EGFR/PI3Kp110β Signaling. Cancers 14 (14) (2022)
Celso Alves, Joana Silva, Susete Pintéus, Romina A Guedes, Rita C Guedes, Rebeca Alvariño, Rafaela Freitas, Márcia I Goettert, Héléna A Gaspar, Amparo Alfonso, Maria C Alpoím, Luis M Botana, Rui Pedrosa
Bromoditerpenes from the Red Seaweed Sphaerococcus coronopifolius as Potential Cytotoxic Agents and Proteasome Inhibitors and Related Mechanisms of Action. Marine drugs 20 (10) (2022)
Rita C Acúrcio, Sabina Pozzi, Barbara Carreira, Marta Pojo, Nuria Gómez-Cebrián, Sandra Casimiro, Adelaide Fernandes, Andreia Barateiro, Vitor Farricha, Joaquim Brito, Ana Paula Leandro, Jorge A R Salvador, Luís Graça, Leonor Puchades-Carrasco, Luís Costa, Ronit Satchi-Fainaro, Rita C Guedes, Helena F Florindo
Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment. Journal for immunotherapy of cancer 10 (7) (2022)
Carlota Leonardo-Sousa, Andreia Neves Carvalho, Romina A Guedes, Pedro M P Fernandes, Natália Aniceto, Jorge A R Salvador, Maria João Gama, Rita C Guedes
Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance. Molecules (Basel, Switzerland) 27 (7) (2022)
Sónia Rocha, Natália Aniceto, Rita C Guedes, Hélio M T Albuquerque, Vera L M Silva, Carlos F M Silva, Maria Luísa Corvo, Eduarda Fernandes, Marisa Freitas
An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles. Nutrients 14 (2) (2022)
Filipe G A Estrada, Silvia Miccoli, Natália Aniceto, Alfonso T García-Sosa, Rita C Guedes
Exploring EZH2-Proteasome Dual-Targeting Drug Discovery through a Computational Strategy to Fight Multiple Myeloma. Molecules (Basel, Switzerland) 26 (18) (2021)
Rafael T Aroso, Rita C Guedes, Mariette M Pereira
Synthesis of Computationally Designed 2,5(6)-Benzimidazole Derivatives via Pd-Catalyzed Reactions for Potential E. coli DNA Gyrase B Inhibition. Molecules (Basel, Switzerland) 26 (5) (2021)
Raquel R Lopes, Catarina S Tomé, Roberto Russo, Roberta Paterna, João Leandro, Nuno R Candeias, Lidia Maria Goncalves, Miguel Teixeira, Pedro M F Sousa, Rita C Guedes, João B Vicente, Pedro M P Gois, António J Almeida
Modulation of Human Phenylalanine Hydroxylase by 3-Hydroxyquinolin-2(1H)-One Derivatives. Biomolecules 11 (3) (2021)
Patrícia A Serra, Nuno Taveira, Rita C Guedes
Computational Modulation of the V3 Region of Glycoprotein gp125 of HIV-2. International journal of molecular sciences 22 (4) (2021)
Luís A R Carvalho, Vanessa T Almeida, José A Brito, Kenneth M Lum, Tânia F Oliveira, Rita C Guedes, Lidia Maria Goncalves, Susana D Lucas, Benjamin F Cravatt, Margarida Archer, Rui Moreira
3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling. ACS chemical biology 15 (4) (2020)
Hugo Brito, Vanda Marques, Marta B Afonso, Dean G Brown, Ulf Börjesson, Nidhal Selmi, David M Smith, Ieuan O Roberts, Martina Fitzek, Natália Aniceto, Rita C Guedes, Rui Moreira, Cecília Maria Pereira Rodrigues
Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibition. Cell death discovery 6 (2020)
Rita C Acúrcio, Carlota Leonardo-Sousa, Alfonso T García-Sosa, Jorge A Salvador, Helena F Florindo, Rita C Guedes
Structural insights and binding analysis for determining the molecular bases for programmed cell death protein ligand-1 inhibition. MedChemComm 10 (10) (2019)
Jean Jacques Vanden Eynde, Arduino Aleksander Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A C Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Gennaro Chiappetta, Jean Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, Francisco Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, Maria Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdieroa, Hong Liu, Peter J H Scott, Cristóbal de Los Ríos, Luigi A Agrofoglio, Simona Collina, Rita C Guedes, Diego Muñoz-Torrero
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6. Molecules (Basel, Switzerland) 25 (1) (2019)
Romina A Guedes, Natália Aniceto, Marina A P Andrade, Jorge A R Salvador, Rita C Guedes
Chemical Patterns of Proteasome Inhibitors: Lessons Learned from Two Decades of Drug Design. International journal of molecular sciences 20 (21) (2019)
Susana Proença, Bernardo Antunes, Rita C Guedes, Filipa Ramilo-Gomes, M Fátima Cabral, Judite Costa, Ana Fátima Carvalho Fernandes, Matilde Castro, Nuno G Oliveira, Joana P Miranda
Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models. International journal of molecular sciences 20 (20) (2019)
Rita C Acúrcio, Anna Scomparin, João Conniot, Jorge A R Salvador, Ronit Satchi-Fainaro, Helena F Florindo, Rita C Guedes
Structure-Function Analysis of Immune Checkpoint Receptors to Guide Emerging Anticancer Immunotherapy. Journal of medicinal chemistry 61 (24) (2018)